Author: M. A. Epstein Publisher: Springer Science & Business Media ISBN: 3642672361 Category : Medical Languages : en Pages : 467
Book Description
The Epstein-Barr virus was discovered 15 years ago. Since that time an immense body of information has been accumu lated on this agent which has come to assume great signifi cance in many different fields of biological science. Thus, the virus has very special relevance in human medicine and oncology, in tumor virology, in immunology, and in mole cular virology, since it is the cause of infectious mononu cleosis and also the first human cancer virus, etiologically related to endemic Burkitt's lymphoma and probably to nasopharyngeal carcinoma. In addition, continuous human lymphoid cell lines initiated and maintained by the transform ing function of the virus genome provide a laboratory tool with wide and ever-growing applications. Innumerable papers on the Epstein-Barr virus have ap peared over recent years and reports of work with this agent now constitute a veritable flood. The present book provides the first and only comprehensive, authoritative over-view of all aspects of the virus by authors who have been the original and major contributors in their particular disciplines. A complete and up-to-date survey of this unique and important agent is thus provided which should be of great interest to experts, teachers, and students engaged in cancer research, virology, immunology, molecular biology, epide miology, and cell culture. Where topics have been dealt with from more than one of these viewpoints, some inevitable overlap and duplication has resulted; although this has been kept to a minimum, it has been retained in some places because of positive usefulness.
Author: Ann Arvin Publisher: Cambridge University Press ISBN: 1139461648 Category : Medical Languages : en Pages : 1325
Book Description
This comprehensive account of the human herpesviruses provides an encyclopedic overview of their basic virology and clinical manifestations. This group of viruses includes human simplex type 1 and 2, Epstein–Barr virus, Kaposi's Sarcoma-associated herpesvirus, cytomegalovirus, HHV6A, 6B and 7, and varicella-zoster virus. The viral diseases and cancers they cause are significant and often recurrent. Their prevalence in the developed world accounts for a major burden of disease, and as a result there is a great deal of research into the pathophysiology of infection and immunobiology. Another important area covered within this volume concerns antiviral therapy and the development of vaccines. All these aspects are covered in depth, both scientifically and in terms of clinical guidelines for patient care. The text is illustrated generously throughout and is fully referenced to the latest research and developments.
Author: Christian Münz Publisher: Springer ISBN: 331922834X Category : Medical Languages : en Pages : 493
Book Description
Epstein Barr virus (EBV) was discovered as the first human tumor virus around 50 years ago. Since its discovery in Burkitt’s lymphoma it has been associated with various other malignancies, infectious mononucleosis and even autoimmune diseases. The two book volumes on EBV summarize the first 50 years of research on this tumor virus, starting with historical perspectives on discovery, oncogenicity and immune control, reviewing the role that the virus plays in the various associated diseases and concluding with a discussion on how the immune system keeps persistent EBV infection under control in healthy EBV carriers and can be used to treat EBV associated diseases. The respective 32 chapters are written by international experts from three continents for health care providers, biomedical researchers and patients that are affected by EBV. The assembled knowledge should help to understand EBV associated diseases better and to develop EBV specific vaccination in the near future.
Author: Institute of Medicine Publisher: National Academies Press ISBN: 0309174988 Category : Medical Languages : en Pages : 472
Book Description
Vaccines have made it possible to eradicate the scourge of smallpox, promise the same for polio, and have profoundly reduced the threat posed by other diseases such as whooping cough, measles, and meningitis. What is next? There are many pathogens, autoimmune diseases, and cancers that may be promising targets for vaccine research and development. This volume provides an analytic framework and quantitative model for evaluating disease conditions that can be applied by those setting priorities for vaccine development over the coming decades. The committee describes an approach for comparing potential new vaccines based on their impact on morbidity and mortality and on the costs of both health care and vaccine development. The book examines: Lessons to be learned from the polio experience. Scientific advances that set the stage for new vaccines. Factors that affect how vaccines are used in the population. Value judgments and ethical questions raised by comparison of health needs and benefits. The committee provides a way to compare different forms of illness and set vaccine priorities without assigning a monetary value to lives. Their recommendations will be important to anyone involved in science policy and public health planning: policymakers, regulators, health care providers, vaccine manufacturers, and researchers.
Author: Dorothy H. Crawford Publisher: Oxford University Press, USA ISBN: 0199653119 Category : Health & Fitness Languages : en Pages : 219
Book Description
This is the story of the discovery of the first human cancer virus. Through intriguing accounts that include some remarkable characters and individual stories from around the globe - including the UK, Africa, USA, and China - it tells the story of the Epstein-Barr virus and the understanding of its connections to a variety of other diseases.
Author: R.C. Kennedy Publisher: Elsevier ISBN: 0080534430 Category : Medical Languages : en Pages : 557
Book Description
This is the most comprehensive review of the idiotypic network available. All the current knowledge of idiotypes of the various antibodies is incorporated in this volume. The pathogenic role of idiotypes in autoimmunity and cancer is reviewed in depth. The therapeutic part focusses on harnessing anti-idiotypes for treating autoimmunological disorders, and on the employment of idiotypes for vaccines in cancer and infectious diseases, as well as explaining the manipulation of the idiotypic network in autoimmunity and cancer idiotypes and vaccines.
Author: Christian Münz Publisher: Springer ISBN: 9783319228211 Category : Medical Languages : en Pages : 0
Book Description
Epstein Barr virus (EBV) was discovered as the first human tumor virus around 50 years ago. Since its discovery in Burkitt’s lymphoma it has been associated with various other malignancies, infectious mononucleosis and even autoimmune diseases. The two book volumes on EBV summarize the first 50 years of research on this tumor virus, starting with historical perspectives on discovery, oncogenicity and immune control, reviewing the role that the virus plays in the various associated diseases and concluding with a discussion on how the immune system keeps persistent EBV infection under control in healthy EBV carriers and can be used to treat EBV associated diseases. The respective 32 chapters are written by international experts from three continents for health care providers, biomedical researchers and patients that are affected by EBV. The assembled knowledge should help to understand EBV associated diseases better and to develop EBV specific vaccination in the near future.
Author: S.H. Oertel Publisher: Springer Science & Business Media ISBN: 364256352X Category : Medical Languages : en Pages : 436
Book Description
This book covers lymphoproliferative disorders in patients with congenital or acquired immunodeficiencies. Acquired immunodeficiencies are caused by infections with the human immunodeficiency virus or arise following immunosuppressive therapy administered after organ transplantation or to treat connective tissue diseases such as rheumatoid arthritis. It was recently discovered that various diseases or therapeutic modalities that induce a state of immunosuppression may cause virally driven lymphoproliferations. This book summarizes for the first time this group of immunodeficiency-associated lymphoproliferations.
Author: P. H. Levine Publisher: Springer Science & Business Media ISBN: 1461245907 Category : Medical Languages : en Pages : 494
Book Description
Since its discovery as the cause of infectious mononucleosis in 1964, the Epstein-Barr virus (EBV) has been etiologically implicated in an increasing number of human diseases. Generally considered the first human oncogenic virus because of a number of studies linking it with Burkitt's lymphoma and nasopharyngeal carcinoma (NPC), as well as its documented oncogenicity in nonhuman primates, EBVhas served as a model for identifying subsequent candidate oncogenic viruses and the stimulus for Evans' revision of the Henle-Koch postulates to accommodate the problems in proving viral oncogenicity in humans. Research on the role of EBV in human cancer was particularly en hanced (a) by the pioneering work of Werner and Gertrude Henle, and (b) by the coordinated efforts of the Special Virus Leukemia Program and its successors, the Special Virus Cancer Program and the Virus Cancer Program of the National Cancer Institute (NCI). Initiated by Dr. Frank J. Rauscher, who subsequently became director of the Ncr and is now Vice-President of the American Cancer Society, and expanded by Dr. John B. Moloney, whose contributions to cancer research were honored at this Second International Symposium on EBV and Associated Malignant Diseases, these NCI contract-sup ported programs brought together investigators from all over the world to participate in a joint effort to unravel the mystery of EBV behavior and pathogenicity. It was these programs that gave us the opportunity to work with such outstanding people as Professor Yohei Ito, to whom this book is dedicated.
Author: Kasia Kines Publisher: ISBN: 9781722895365 Category : Languages : en Pages : 586
Book Description
From the Best Selling author Dr. Kasia Kines. Take your life back! For anyone suffering from Epstein-Barr Virus (EBV), chronic fatigue, autoimmune disorders, Infectious Mononucleosis, or other mystery illnesses, this is a must read!Do you feel lost and hopeless, living a life of illness with no answers? Do you feel unsupported by your medical team, left to suffer alone with no guidance? Are you searching for solutions to get your health and life back on track?Finally, a book that speaks to both the medical community and people inflicted by both mono and chronic conditions caused by EBV!The expanse of this pivotal book is far reaching - many people may not yet know they have been infected with EBV (commonly known as the "kissing disease"), but yet they struggle every day with chronic symptoms such as severe brain fog, debilitating fatigue, headaches, fever, chills, sore throat, body aches, and abdominal discomfort and can't seem to find a successful treatment solution.Eventually, some go on to develop autoimmune disorders, e.g. Lupus, Multiple Sclerosis, or Hashimoto's Thyroiditis and even cancer and are told that their immune system is simply confused and is now attacking itself, left with no solutions or hope for recovery.Alarmingly, chronic EBV infection is almost completely missed in medical practice, and as a result of never being tested, misinterpreting the test results, not being diagnosed, or being mis-diagnosed by their doctors, millions of people suffer debilitating conditions for many years with no answers.But this suffering can be avoided. And with this book, answers can be found.Author Dr. Kasia Kines is considered by her colleagues to be "one of the most brilliant, and importantly, clinically experienced functional nutritionists in the world." In Epstein-Barr Virus Solution, Dr. Kines provides a groundbreaking examination of EBV and not only how it causes chronic fatigue, autoimmune disorders, and even cancer but also how recovery is possible. This book was written in hopes that it will globally change the way EBV is understood, diagnosed, and treated.The deep journey into the existing research sheds light on the EBV virus for both the seasoned medical community and the layperson. Along with the validated research, Epstein-Barr Virus Solution presents practical, time-tested, and evidence-based clinical solutions for the testing and medical nutrition therapy for EBV, testing and lab interpretation, unique supplementation protocols, recovery strategies for stress, insomnia, fatigue, and toxicity, pantry and kitchen rehab for EBV, and delicious anti-EBV recipes. Through Dr. Kines' compassionate guidance, readers will feel confident to discuss their concerns with their doctor, to ask for testing, and to take their lives back from EBV. Epstein-Barr Virus Solution urges medical providers to hear their clients' concerns and provides the medical community with the research and insights needed to avoid misdiagnosis and common problems with testing for EBV.Epstein-Barr Virus Solution was made possible because of Dr. Kines' long-standing expertise as a functional clinical nutritionist who has dedicated her practice to working with clients inflicted by EBV. Dr. Kines tells readers in easy-to-understand language that recovery and hope for better health are possible through targeted nutrition and lifestyle changes. Readers are given a toolkit full of practical advice and guidance, including exclusive materials from Dr. Kines' life-changing 30-Day Detox Program that she has taught successfully for over 10 years.The research is out there, and Dr. Kasia Kines has found it, synthesized it, and utilized it to implement successful treatment protocols in her own clinic. Clients who had suffered years with chronic EBV infection symptoms are now recovering and living their lives.This book will provide those infected with EBV everything they need to finally take control of their health and take their life and happiness back.
Author: M. A. Epstein
Author: Ann Arvin
Author: Christian Münz
Author: Institute of Medicine
Author: Dorothy H. Crawford
Author: R.C. Kennedy
Author: Christian Münz
Author: S.H. Oertel
Author: P. H. Levine
Author: Kasia Kines