Epigenetic pathways in PTSD: how traumatic experiences leave their signature on the genome PDF Download

Author: Tania L Roth
Publisher: Frontiers Media SA
ISBN: 2889194582
Category : Epigenetics
Languages : en
Pages : 159

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Book Description
This research topic focuses on epigenetic components of PTSD. Epigenetic mechanisms are a class of molecular mechanisms by which environmental influences, including stress, can interact with the genome to have long-term consequences for brain plasticity and behavior. Articles herein include empirical reports and reviews that link stress and trauma with epigenetic alterations in humans and animal models of early- or later-life stress. Themes present throughout the collection include: DNA methylation is a useful biomarker of stress and treatment outcome in humans; epigenetic programming of stress-sensitive physiological systems early in development confers an enhanced risk on disease development upon re-exposure to trauma or stress; and, long-lived fear memories are associated with epigenetic alterations in fear memory and extinction brain circuitry.

Author: Claus Kreß
Publisher:
ISBN: 0197537375
Category : Law
Languages : en
Pages : 527

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Book Description
There are legal limits on the circumstances under which states may use military force to address a perceived or actual threat. The concepts of necessity and proportionality are central to these limitations imposed by the law. Necessity and Proportionality in International Peace and Security Law explores the many ways in which necessity and proportionality arise in the law on the modern battlefield, which is rapidly changing, complex, and ambiguous.

Author: Matthew Tull
Publisher: Academic Press
ISBN: 0128162899
Category : Psychology
Languages : en
Pages : 654

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Book Description
Emotion in Posttraumatic Stress Disorder provides an up-to-date review of the empirical research on the relevance of emotions, such as fear, anxiety, shame, guilt, and disgust to posttraumatic stress disorder (PTSD). It also covers emerging research on the psychophysiology and neurobiological underpinnings of emotion in PTSD, as well as the role of emotion in the behavioral, cognitive, and affective difficulties experienced by individuals with PTSD. It concludes with a review of evidence-based treatment approaches for PTSD and their ability to mitigate emotion dysfunction in PTSD, including prolonged exposure, cognitive processing therapy, and acceptance-based behavioral therapy. - Identifies how emotions are central to understanding PTSD. - Explore the neurobiology of emotion in PTSD. - Discusses emotion-related difficulties in relation to PTSD, such as impulsivity and emotion dysregulation. - Provides a review of evidence-based PTSD treatments that focus on emotion.

Author: Victor G. Carrión
Publisher: Oxford University Press
ISBN: 0190201967
Category : Health & Fitness
Languages : en
Pages : 201

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Book Description
Drs Carrion and Weems present the first book to be published on the neuroscience of pediatric PTSD. Children who experience traumatic stress early in life are at risk of developing scholastic, social, emotional and cognitive difficulties. In this work, the authors present a compelling story on how neuroscience findings explain the difficulties these children are challenged with

Author: Peter Meineck
Publisher: Taylor & Francis
ISBN: 1315466562
Category : Art
Languages : en
Pages : 239

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Book Description
This book examines classical Greek theatre, asking how ancient drama operated in performance and became such an influential social, cultural and political force. Meineck approaches Greek theatre from the perspective of the cognitive sciences as an embodied live enacted event, and analyses how different performative elements acted upon audiences to create absorbing narrative action, emotional intensity, intellectual reflection and empathy. This was the key to the transformative artistic and social power that enabled Greek drama to advance alternate viewpoints. He also explores what the model of Greek drama can reveal about live theatre's value in cultural, social and political discourse today.

Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 030944070X
Category : Law
Languages : en
Pages : 362

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Book Description
Bullying has long been tolerated as a rite of passage among children and adolescents. There is an implication that individuals who are bullied must have "asked for" this type of treatment, or deserved it. Sometimes, even the child who is bullied begins to internalize this idea. For many years, there has been a general acceptance and collective shrug when it comes to a child or adolescent with greater social capital or power pushing around a child perceived as subordinate. But bullying is not developmentally appropriate; it should not be considered a normal part of the typical social grouping that occurs throughout a child's life. Although bullying behavior endures through generations, the milieu is changing. Historically, bulling has occurred at school, the physical setting in which most of childhood is centered and the primary source for peer group formation. In recent years, however, the physical setting is not the only place bullying is occurring. Technology allows for an entirely new type of digital electronic aggression, cyberbullying, which takes place through chat rooms, instant messaging, social media, and other forms of digital electronic communication. Composition of peer groups, shifting demographics, changing societal norms, and modern technology are contextual factors that must be considered to understand and effectively react to bullying in the United States. Youth are embedded in multiple contexts and each of these contexts interacts with individual characteristics of youth in ways that either exacerbate or attenuate the association between these individual characteristics and bullying perpetration or victimization. Recognizing that bullying behavior is a major public health problem that demands the concerted and coordinated time and attention of parents, educators and school administrators, health care providers, policy makers, families, and others concerned with the care of children, this report evaluates the state of the science on biological and psychosocial consequences of peer victimization and the risk and protective factors that either increase or decrease peer victimization behavior and consequences.

Author: Charles L. Chavis Jr.
Publisher: JHU Press
ISBN: 1421442930
Category : History
Languages : en
Pages : 305

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Book Description
The definitive account of the lynching of twenty-three-year-old Matthew Williams in Maryland, the subsequent investigation, and the legacy of "modern-day" lynchings. On December 4, 1931, a mob of white men in Salisbury, Maryland, lynched and set ablaze a twenty-three-year-old Black man named Matthew Williams. His gruesome murder was part of a wave of silent white terrorism in the wake of the stock market crash of 1929, which exposed Black laborers to white rage in response to economic anxieties. For nearly a century, the lynching of Matthew Williams has lived in the shadows of the more well-known incidents of racial terror in the deep South, haunting both the Eastern Shore and the state of Maryland as a whole. In The Silent Shore, author Charles L. Chavis Jr. draws on his discovery of previously unreleased investigative documents to meticulously reconstruct the full story of one of the last lynchings in Maryland. Bringing the painful truth of anti-Black violence to light, Chavis breaks the silence that surrounded Williams's death. Though Maryland lacked the notoriety for racial violence of Alabama or Mississippi, he writes, it nonetheless was the site of at least 40 spectacle lynchings after the abolition of slavery in 1864. Families of lynching victims rarely obtained any form of actual justice, but Williams's death would have a curious afterlife: Maryland's politically ambitious governor Albert C. Ritchie would, in an attempt to position himself as a viable challenger to FDR, become one of the first governors in the United States to investigate the lynching death of a Black person. Ritchie tasked Patsy Johnson, a member of the Pinkerton detective agency and a former prizefighter, with going undercover in Salisbury and infiltrating the mob that murdered Williams. Johnson would eventually befriend a young local who admitted to participating in the lynching and who also named several local law enforcement officers as ringleaders. Despite this, a grand jury, after hearing 124 witness statements, declined to indict the perpetrators. But this denial of justice galvanized Governor Ritchie's Interracial Commission, which would become one of the pioneering forces in the early civil rights movement in Maryland. Complicating historical narratives associated with the history of lynching in the city of Salisbury, The Silent Shore explores the immediate and lingering effect of Williams's death on the politics of racism in the United States, the Black community in Salisbury, the broader Eastern Shore, the state of Maryland, and the legacy of "modern-day lynchings."

Author: Arlene Vetere
Publisher: Routledge
ISBN: 1317417011
Category : Psychology
Languages : en
Pages : 515

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Book Description
Narrative Therapies with Children and their Families introduces and develops the principles of narrative approaches to systemic therapeutic work, and shows how they can provide a powerful framework for engaging troubled children and their families. Written by eminent and leading clinicians, known nationally and internationally for their research and theory development in the field of child and family mental health, the book covers a broad range of difficult and sensitive topics, including trauma, abuse and youth offending. It illustrates the wide application of these principles in the context of the particular issues and challenges presented when working with children and families. Since publication of the first edition, the importance of narrative therapy has continued to grow, and this new edition provides an updated and revised overview of the field, along with three new chapters to keep apace with developments in child mental health trauma work. This book remains a key text in the field of systemic narrative training and practice. With clinical examples throughout, this practical book will be welcomed by family and systemic therapists and other professionals in the field of child, adolescent and family mental health.

Author: Emily J. Hogg
Publisher: Bloomsbury Publishing
ISBN: 1350166715
Category : Literary Criticism
Languages : en
Pages : 225

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Book Description
The contemporary moment is characterized by precarity – an expanding and intensifying vulnerability conditioned by political and economic structures. Using literary and cultural texts to develop a nuanced and critical exploration of the concept of precarity that emphasizes its contemporary manifestations while also attending to its historical roots and existential dimensions, this book examines the vulnerabilities which characterize our anxious existence, including unemployment, environmental crisis, temporary contracts and patterns of migration. Broken down into three key themes of feelings, bodies and time, Precarity in Contemporary Literature and Culture asks whether precarity can be considered a new phenomenon; explores the relationship between precarity and traditional class politics; analyses precarity's global dimensions; and reflects on the links between contemporary crisis and underlying existential human vulnerability. With reference to a wide range of forms such as contemporary, realist, science fiction and modernist novels, film, theatre, and the lyric poem, this book goes beyond one national context to consider texts from the US, UK, Germany and South Africa.

Author: Jeroen Lauwers
Publisher: Walter de Gruyter GmbH & Co KG
ISBN: 3110482207
Category : Literary Criticism
Languages : en
Pages : 334

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Book Description
While the field of classics has informed and influenced the early developments of the field of psychology, these two disciplines presently enjoy fewer fruitful cross-fertilizations than one would expect. This book shows how the study of classics can help psychologists anchor their scientific findings in a historical, literary and philosophical framework, while insights of contemporary psychology offer new hermeneutic methods and explanations to classicists. This book is the first to date to offer a wide-ranging overview of the possibilities of marrying contemporary trends in psychology and classical studies. Advocating a critical dialogue between both disciplines, it offers novel reflections on psychotherapy, ancient philosophy, social psychology, literature and its theory, historiography, psychoanalysis, tragedy, the philosophy of mind, linguistics and reception. With twenty contributions by specialists in different fields, it promotes the combination of classical and psychological perspectives, and demonstrates the methods and rewards of such an endeavour through concrete case studies. This pioneering book is thus intended for all readers who seek inspiration for their readings, research, or therapeutic practice.