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Author: Dirk Tischler Publisher: MDPI ISBN: 3039437836 Category : Science Languages : en Pages : 130
Book Description
Marine habitats are promising sources to identify novel organisms and compounds. A total of 70% of the planet’s surface is covered by ocean, and little is known about the biosphere within these habitats. In the last few years, numerous novel bioactive compounds or secondary metabolites from marine environments have been described. This is, and will be, a promising source of candidate compounds in pharma research and chemical biology. In recent years, a number of novel techniques have been introduced to the field and it has become easier to actually (bio-)prospect compounds such as enzyme inhibitors. Those novel compounds then need to be characterized and evaluated in comparison to well-known representatives. This Special Issue focuses on the description of novel enzyme inhibitors of marine origin, including bioprospecting, omic approaches, and structural and mechanistic aspects.
Author: Dirk Tischler Publisher: MDPI ISBN: 3039437836 Category : Science Languages : en Pages : 130
Book Description
Marine habitats are promising sources to identify novel organisms and compounds. A total of 70% of the planet’s surface is covered by ocean, and little is known about the biosphere within these habitats. In the last few years, numerous novel bioactive compounds or secondary metabolites from marine environments have been described. This is, and will be, a promising source of candidate compounds in pharma research and chemical biology. In recent years, a number of novel techniques have been introduced to the field and it has become easier to actually (bio-)prospect compounds such as enzyme inhibitors. Those novel compounds then need to be characterized and evaluated in comparison to well-known representatives. This Special Issue focuses on the description of novel enzyme inhibitors of marine origin, including bioprospecting, omic approaches, and structural and mechanistic aspects.
Author: Paula B. Andrade Publisher: John Wiley & Sons ISBN: 3527342052 Category : Medical Languages : en Pages : 348
Book Description
The past decade has seen the reappearance of natural products as a valuable source of potent therapeutics. Here, experts on bioactive natural products cover the full spectrum of clinically relevant enzymes that are known to be targeted by natural products. Key enzymes include acetylcholine esterase, angiotensin-I-converting enzyme, cyclooxygenase, dihydrofolate reductase, phospholipase A2, respiratory complexes, and many more. By connecting the diversity of medicinal natural product sources with their potential clinical applications, this volume serves as a companion for the medicinal chemist looking for innovative small molecule compounds as well as for pharmacologist interested in the clinical effects and mode of action of herbal and traditional medicines.
Author: Murat Şentürk Publisher: BoD – Books on Demand ISBN: 9535130579 Category : Science Languages : en Pages : 270
Book Description
Over the recent years, medicinal chemistry has become responsible for explaining interactions of chemical molecule processes such that many scientists in the life sciences from agronomy to medicine are engaged in medicinal research. This book contains an overview focusing on the research area of enzyme inhibitor and activator, enzyme-catalyzed biotransformation, usage of microbial enzymes, enzymes associated with programmed cell death, natural products as potential enzyme inhibitors, protease inhibitors from plants in insect pest management, peptidases, and renin-angiotensin system. The book provides an overview on basic issues and some of the recent developments in medicinal science and technology. Especially, emphasis is devoted to both experimental and theoretical aspect of modern medicine. The primary target audience for the book includes students, researchers, chemists, molecular biologists, medical doctors, pharmacologists, and professionals who are interested in associated areas. The textbook is written by international scientists with expertise in biochemistry, enzymology, molecular biology, and genetics, many of which are active in biochemical and pharmacological research. I would like to acknowledge the authors for their contribution to the book. We hope that the textbook will enhance the knowledge of scientists in the complexities of some medical approaches; it will stimulate both professionals and students to dedicate part of their future research in understanding relevant mechanisms and applications of pharmacology.
Author: Tatiana V. Ovchinnikova Publisher: MDPI ISBN: 3039215329 Category : Medical Languages : en Pages : 442
Book Description
This Special Issue Book, “Marine Bioactive Peptides: Structure, Function, and Therapeutic Potential" includes up-to-date information regarding bioactive peptides isolated from marine organisms. Marine peptides have been found in various phyla, and their numbers have grown in recent years. These peptides are diverse in structure and possess broad-spectrum activities that have great potential for medical applications. Various marine peptides are evolutionary ancient molecular factors of innate immunity that play a key role in host defense. A plethora of biological activities, including antibacterial, antifungal, antiviral, anticancer, anticoagulant, endotoxin-binding, immune-modulating, etc., make marine peptides an attractive molecular basis for drug design. This Special Issue Book presents new results in the isolation, structural elucidation, functional characterization, and therapeutic potential evaluation of peptides found in marine organisms. Chemical synthesis and biotechnological production of marine peptides and their mimetics is also a focus of this Special Issue Book.
Author: Norman F. Haard Publisher: CRC Press ISBN: 1482289911 Category : Technology & Engineering Languages : en Pages : 708
Book Description
"Reviews specific enzymes and enzyme groups studied in recent years, delves into the relationship between enzymes and seafood quality, covers the application of enzymes as seafood processing aids, and focuses on the recovery of useful enzymes as by-products from seafood waste. Details the control of enzyme activity in seafood products."
Author: A.M. Martin Publisher: Springer Science & Business Media ISBN: 1461553032 Category : Technology & Engineering Languages : en Pages : 509
Book Description
The fish processing industry is still far from the levels of scientific and technological development that characterize other food processing oper ations. It has also been slow in finding uses for by-products and processing wastes, compared with the meat and poultry industries. The utilization of fisheries by-products or wastes constitutes an area in which the application of modern techniques could potentially improve profitability. At present, increased attention is being focused on the application of new biotechnological methods to operations related to the seafood industry, with the objective of increasing its general efficiency. Because fish processing operations are commonly carried out in the vicinity of the sea, most of the resulting fish wastes have been disposed of by returning them to it. Pollution control measures and a better understanding of the valuable composition of the products extracted from the sea are expected to encourage their recovery and the develop ment of new products from them. In the past, fisheries wastes and species not used for food have been generally utilized through techno logical processes with a low level of sophistication, such as those for the production of animal feed and fertilizer. Limited economic success has accompanied the application of physi cal and chemical processes for the recovery of non-utilized fisheries biomass and for the production of quality products from them.
Author: James B. McClintock Publisher: CRC Press ISBN: 1420036602 Category : Science Languages : en Pages : 626
Book Description
The interdisciplinary field of marine chemical ecology is an expanding and dynamic science. It is no surprise that the breadth of marine organisms studied expanded in concert with developments in underwater technology. With its up-to-date subject reviews by experts, Marine Chemical Ecology is the most current, comprehensive book on the subject. The
Author: Herminia Domínguez Publisher: MDPI ISBN: 3036502645 Category : Science Languages : en Pages : 230
Book Description
Phenolic compounds are an extremely diverse class of ubiquitous secondary metabolites produced by a variety of organisms playing different biological roles. They have numerous types of demonstrated bioactivities, including antioxidant, antimicrobial, anti-inflammatory, antitumoral, immunomodulator, neuroprotective, cardioprotective, and antidiabetic activities. Marine organisms produce a vast collection of unique phenolic structures, some of them not found in terrestrial habitats. Progress in different aspects is rapidly advancing, and this Special Issue will provide updated information and recent studies on marine phenolics. Specially, this issue is focused on their chemical characterization, elucidation of their structures, evaluation of their biological properties and mechanisms of action, efficient extraction and purification technologies, development of value-added applications, as well as formulation of novel products.
Author: Paula B. Andrade Publisher: John Wiley & Sons ISBN: 3527805931 Category : Medical Languages : en Pages : 418
Book Description
The past decade has seen the reappearance of natural products as a valuable source of potent therapeutics. Here, experts on bioactive natural products cover the full spectrum of clinically relevant enzymes that are known to be targeted by natural products. Key enzymes include acetylcholine esterase, angiotensin-I-converting enzyme, cyclooxygenase, dihydrofolate reductase, phospholipase A2, respiratory complexes, and many more. By connecting the diversity of medicinal natural product sources with their potential clinical applications, this volume serves as a companion for the medicinal chemist looking for innovative small molecule compounds as well as for pharmacologist interested in the clinical effects and mode of action of herbal and traditional medicines.
Author: Dirk Tischler
Author: Dirk Tischler
Author: Paula B. Andrade
Author: 
Author: Murat Şentürk
Author: Tatiana V. Ovchinnikova 
Author: Norman F. Haard
Author: A.M. Martin
Author: James B. McClintock
Author: Herminia Domínguez
Author: Paula B. Andrade