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Author: Thomas E. Barman Publisher: Springer Science & Business Media ISBN: 3642866026 Category : Science Languages : en Pages : 508
Book Description
I t is a pleasure to write a few lines to welcome this labour of Iove. I t is always dangeraus to draw sharp divisions between the interests of different scientists. However, in the present stage of progress in enzymology, there are those who are primarily interested in the molecular mechanisms of the reactions of a few selected enzymes, while others are involved in the grand scheme of the chemical metabolism of cells or whole organisms. Fortunately Dr. Barman has had experience in both the molecular and the metabolic aspects of enzymology. He therefore knows the require ments of research workers interested in enzymes from many different points of view. It would be foolish to hope that a handbook of this kind will provide all the information about enzymes which different specialists would wish to find. The author has attempted to help users in the following way. If one Iooks up a particular enzyme one will find all the basic data and a very good Iist of references for more specialized information. Apart from selection of the type of information provided, the author's judgement on the reliability of data is, of course, of critical importance in a handbook. If contradicting published information about some property of an enzyme has to be sorted out, it is often neither possible to teil the whole story nor to give an objective judgement.
Author: Thomas E. Barman Publisher: Springer Science & Business Media ISBN: 3642866026 Category : Science Languages : en Pages : 508
Book Description
I t is a pleasure to write a few lines to welcome this labour of Iove. I t is always dangeraus to draw sharp divisions between the interests of different scientists. However, in the present stage of progress in enzymology, there are those who are primarily interested in the molecular mechanisms of the reactions of a few selected enzymes, while others are involved in the grand scheme of the chemical metabolism of cells or whole organisms. Fortunately Dr. Barman has had experience in both the molecular and the metabolic aspects of enzymology. He therefore knows the require ments of research workers interested in enzymes from many different points of view. It would be foolish to hope that a handbook of this kind will provide all the information about enzymes which different specialists would wish to find. The author has attempted to help users in the following way. If one Iooks up a particular enzyme one will find all the basic data and a very good Iist of references for more specialized information. Apart from selection of the type of information provided, the author's judgement on the reliability of data is, of course, of critical importance in a handbook. If contradicting published information about some property of an enzyme has to be sorted out, it is often neither possible to teil the whole story nor to give an objective judgement.
Author: Alan J. Barrett Publisher: Elsevier ISBN: 0080984150 Category : Science Languages : en Pages : 1182
Book Description
Handbook of Proteolytic Enzymes, Second Edition, Volume 1: Aspartic and Metallo Peptidases is a compilation of numerous progressive research studies on proteolytic enzymes. This edition is organized into two main sections encompassing 328 chapters. This handbook is organized around a system for the classification of peptidases, which is a hierarchical one built on the concepts of catalytic type, clan, family and peptidase. The concept of catalytic type of a peptidase depends upon the chemical nature of the groups responsible for catalysis. The recognized catalytic types are aspartic, cysteine, metallo, serine, threonine, and the unclassified enzymes, while clans and families are groups of homologous peptidases. Homology at the level of a family of peptidases is shown by statistically significant relationship in amino acid sequence to a representative member called the type example, or to another member of the family that has already been shown to be related to the type example. Each chapter discusses the history, activity, specificity, structural chemistry, preparation, and biological aspects of the enzyme. This book will prove useful to enzyme chemists and researchers.
Author: Dietmar Schomburg Publisher: Springer Science & Business Media ISBN: 9783540005193 Category : Science Languages : en Pages : 660
Book Description
The Springer Handbook of Enzymes provides concise data on some 5,000 enzymes sufficiently well characterized – and here is the second, updated edition. Their application in analytical, synthetic and biotechnology processes as well as in food industry, and for medicinal treatments is added. Data sheets are arranged in their EC-Number sequence. The new edition reflects considerable progress in enzymology: the total material has more than doubled, and the complete 2nd edition consists of 39 volumes plus Synonym Index. Starting in 2009, all newly classified enzymes are treated in Supplement Volumes.
Author: Robert A. Copeland Publisher: John Wiley & Sons ISBN: 0471461857 Category : Science Languages : en Pages : 416
Book Description
Fully updated and expanded-a solid foundation for understandingexperimental enzymology. This practical, up-to-date survey is designed for a broadspectrum of biological and chemical scientists who are beginning todelve into modern enzymology. Enzymes, Second Editionexplains the structural complexities of proteins and enzymes andthe mechanisms by which enzymes perform their catalytic functions.The book provides illustrative examples from the contemporaryliterature to guide the reader through concepts and data analysisprocedures. Clear, well-written descriptions simplify the complexmathematical treatment of enzyme kinetic data, and numerouscitations at the end of each chapter enable the reader to accessthe primary literature and more in-depth treatments of specifictopics. This Second Edition of Enzymes: A Practical Introductionto Structure, Mechanism, and Data Analysis features refinedand expanded coverage of many concepts, while retaining theintroductory nature of the book. Important new featuresinclude: A new chapter on protein-ligand binding equilibria Expanded coverage of chemical mechanisms in enzyme catalysisand experimental measurements of enzyme activity Updated and refined discussions of enzyme inhibitors andmultiple substrate reactions Coverage of current practical applications to the study ofenzymology Supplemented with appendices providing contact information forsuppliers of reagents and equipment for enzyme studies, as well asa survey of useful Internet sites and computer software forenzymatic data analysis, Enzymes, Second Edition isthe ultimate practical guide for scientists and students inbiochemical, pharmaceutical, biotechnical, medicinal, andagricultural/food-related research.
Author: Richard R Burgess Publisher: Academic Press ISBN: 0080923178 Category : Science Languages : en Pages : 915
Book Description
Guide to Protein Purification, Second Edition provides a complete update to existing methods in the field, reflecting the enormous advances made in the last two decades. In particular, proteomics, mass spectrometry, and DNA technology have revolutionized the field since the first edition's publication but through all of the advancements, the purification of proteins is still an indispensable first step in understanding their function. This volume examines the most reliable, robust methods for researchers in biochemistry, molecular and cell biology, genetics, pharmacology and biotechnology and sets a standard for best practices in the field. It relates how these traditional and new cutting-edge methods connect to the explosive advancements in the field. This "Guide to" gives imminently practical advice to avoid costly mistakes in choosing a method and brings in perspective from the premier researchers while presents a comprehensive overview of the field today. - Gathers top global authors from industry, medicine, and research fields across a wide variety of disciplines, including biochemistry, genetics, oncology, pharmacology, dermatology and immunology - Assembles chapters on both common and less common relevant techniques - Provides robust methods as well as an analysis of the advancements in the field that, for an individual investigator, can be a demanding and time-consuming process
Author: Ronald E. Wrolstad Publisher: John Wiley & Sons ISBN: 0471709093 Category : Science Languages : en Pages : 1397
Book Description
Emphasizing effective, state-of-the art methodology and written by recognized experts in the field, the Handbook of Food Analytical Chemistry is an indispensable reference for food scientists and technologists to enable successful analysis. * Provides detailed reports on experimental procedures * Includes sections on background theory and troubleshooting * Emphasizes effective, state-of-the art methodology, written by recognized experts in the field * Includes detailed instructions with annotated advisory comments, key references with annotation, time considerations and anticipated results
Author: Andreas Vogel Publisher: John Wiley & Sons ISBN: 3527343857 Category : Science Languages : en Pages : 430
Book Description
This reference is a "must-read": It explains how an effective and economically viable enzymatic process in industry is developed and presents numerous successful examples which underline the efficiency of biocatalysis.
Author: Daniel L. Purich Publisher: Elsevier ISBN: 0123809258 Category : Science Languages : en Pages : 915
Book Description
Far more than a comprehensive treatise on initial-rate and fast-reaction kinetics, this one-of-a-kind desk reference places enzyme science in the fuller context of the organic, inorganic, and physical chemical processes occurring within enzyme active sites. Drawing on 2600 references, Enzyme Kinetics: Catalysis & Control develops all the kinetic tools needed to define enzyme catalysis, spanning the entire spectrum (from the basics of chemical kinetics and practical advice on rate measurement, to the very latest work on single-molecule kinetics and mechanoenzyme force generation), while also focusing on the persuasive power of kinetic isotope effects, the design of high-potency drugs, and the behavior of regulatory enzymes. - Historical analysis of kinetic principles including advanced enzyme science - Provides both theoretical and practical measurements tools - Coverage of single molecular kinetics - Examination of force generation mechanisms - Discussion of organic and inorganic enzyme reactions
Author: Dietmar Schomburg Publisher: Springer Science & Business Media ISBN: 3642589480 Category : Science Languages : en Pages : 711
Book Description
Today, as the large international genome sequence projects are gaining a great amount of public atte_ntion and huge sequence data bases are created it be comes more and more obvious that we are very limited in our ability to access functional data for the gene products - the proteins, in particular for enzymes. Those data are inherently very difficult to collect, interpret and standardize as they are highly distributed among journals from different fields and are often sub ject to experimental conditions. Nevertheless a systematic collection is essential for our interpretation of the genome information and more so for possible appli cations of this knowledge in the fields of medicine, agriculture, etc .. Recent pro gress on enzyme immobilization, enzyme production, enzyme inhibition, coen zyme regeneration and enzyme engineering has opened up fascinating new fields for the potential application of enzymes in a large range of different areas. It is the functional profile of an enzyme that enables a biologist or physician to analyse a metabolic pathway and its disturbance; it is the substrate specificity of an enzyme which tells an analytical biochemist how to design an assay; it is the stability, specificity and efficiency of an enzyme which determines its usefulness in the biotechnical transformation of a molecule. And the sum of all these data will have to be considered when the deSigner of artificial biocatalysts has to choose the optimum prototype to start with.
Author: Thomas E. Barman
Author: Thomas E. Barman
Author: Alan J. Barrett
Author: Dietmar Schomburg
Author: Robert A. Copeland
Author: Richard R Burgess
Author: Howard F. Loomis
Author: Ronald E. Wrolstad
Author: Andreas Vogel
Author: Daniel L. Purich
Author: Dietmar Schomburg