Endogenous opioids in systems neuroscience PDF Download

Author: Hugo Tejeda
Publisher: Frontiers Media SA
ISBN: 2832528449
Category : Science
Languages : en
Pages : 176

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Author: Patrick L. Kerr
Publisher: Springer Nature
ISBN: 3031454936
Category :
Languages : en
Pages : 456

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Author: Ulrich F. Lanius, PhD
Publisher: Springer Publishing Company
ISBN: 0826106315
Category : Medical
Languages : en
Pages : 537

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Author: Osborne F.X. Almeida
Publisher: Springer Science & Business Media
ISBN: 3642466605
Category : Medical
Languages : en
Pages : 453

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Book Description
Dedicated to Professor Albert Herz, a leading investigator in opioid research, this book provides comprehensive information on the biology of exogenous and endogenous opioids. Contributions by experts in the field discuss recent advances and provide systematic, up-to-date reviews of the physiology and pharmacology of opioids, as well as on the cellular and molecular mechanisms underlying opioid actions. In recognition of the diverse methodologies now available to researchers, each chapter details the approaches used to address a specific issue and provides an in-depth analysis of the data obtained by these various experimental approaches. The clinical relevance of recent findings, as well as future directions, in opioid research are also discussed. This volume thus represents a timely and invaluable sourcebook for researchers, clinicians, and students interested in opioids and peptidergic systems.

Author:
Publisher: Academic Press
ISBN: 0444641688
Category : Medical
Languages : en
Pages : 268

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Book Description
The Opioid System as the Brain’s Interface between Cognition and Motivation, Volume 239, focuses on the opioid system as the interface between the brain’s cognitive and motivational systems. As the opioid system is widely distributed through the brain, particularly in areas implicated in cognition (hippocampus, prefrontal cortex, claustrum, thalamus) and motivation (hypothalamus, amygdala, pontine nuclei, periaqueductal gray and medulla), this book provides chapters that address ongoing research on topics such as the Brain’s cognitive system, the Brain’s motivational system, Antidepressant prescription patterns, Antidepressant-like effects of opioid receptor modulators, the Behavioral effects of antidepressant and anxiolytic drugs, and more. Contains contributions from both academia and industry to maximize the cross-fertilization of differing perspectives on opioid system function in health and disease Studies the opioid system as the interface between the brain’s cognitive and motivational systems

Author: Ronald P. Hammer, Jr.
Publisher: CRC Press
ISBN: 9780849379321
Category : Science
Languages : en
Pages : 440

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Book Description
This collection of reports by eminent researchers provides a complete description of the effects of opiates on the central nervous system of developing and adult animals. The work is useful to investigators interested in opiate neurobiology and clinicians seeking to understand opiate abuse. The Neurobiology of Opiates is organized into sections which describe the wide diversity of opiate actions from cellular and molecular to developmental and behavioral. Normal functions of endogenous opioid peptides and functional effects of exogenous opiate exposure are examined using the latest in vivo and in vitro methods. Particular emphasis is placed on the physiological and pharmacological effects of opiate dependence and withdrawal, in addition to the mechanism of opiate reinforcement and molecular mechanisms of opiate regulation. Opiate actions on the developing brain and in the hypothalamo-pituitary-adrenal axis are also discussed. This comprehensive text provides readers with the latest results and challenges them with new directions for opiate research.

Author: L F Tseong
Publisher: CRC Press
ISBN: 9783718656325
Category : Medical
Languages : en
Pages : 542

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Book Description
This book is being published at a time when opioid receptors have recently been cloned. The structural characteristics of opioid receptors and the recent advances in their molecular cloning and expression are explicated. Connecting these cloned opioid receptors with the pharmacology of opioid receptor actions is of particular importance. The use of antisense oligodeoxynucleotides to opioid receptors to elucidate the neural mechanisms of opioid action is detailed. As analgesia is one of the most important clinical functions for opioids and opioid peptides, this book concentrates on the detailed mechanisms of action of opioids and opioid peptides for the production of analgesia. The significant pharmacologic actions of opioids and opioid peptides in gastrointestinal function, immune function, cardiovascular and respiratory regulation, addiction and the cellular mechanisms involved in tolerance and dependence of opioids are also described. The book will be of interest both to researchers investigating the neural mechanisms of the pharmacologic and physiologic functions of the endogenous opioid system and to clinicians who are involved in pain management and assessment.

Author: Ying Xia
Publisher: Springer Science & Business Media
ISBN: 3642108571
Category : Medical
Languages : en
Pages : 490

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Book Description
Acupuncture therapy has been practiced in China and other Asian countries for more than two thousand years. Modern clinical research has confirmed the impressive therapeutic effect of acupuncture on numerous human ailments, such as controlling pain, nausea, and vomiting. However, the biological mechanisms of acupuncture are still under debate. In Traditional Chinese Medicine (TCM), the mechanism of acupuncture therapy is explained by a meridian model. According to this model, acupuncture is believed to treat the diseased organs by modulating two conditions known as Yin and Yang, which represent all the opposite principles that people find in the universe, both inside and outside the human body. Yin and Yang complement each other, and are subjected to changes between each other. The balance of Yin and Yang is thought to be maintained by Qi, an energy substance flowing constantly through the meridian, a network connecting all the organs of the body. The illness, according to this theory, is the temporary dominance of one principle over the other, owing to the blockade of the Qi from flowing through the meridian under certain circumstance. The axiom of “No stagnation, No pain” in TCM summarizes this concept. Thus, the goal of acupuncture treatment is to restore the balance of Yin and Yang conditions in the diseased organ(s). This theory has been considered to be useful to guide this ancient therapy, such as carrying out diagnosis, deciding on the principle, and selecting the acupoints.

Author: Howard L. Fields
Publisher: Elsevier Publishing Company
ISBN: 9780444809841
Category : Medical
Languages : en
Pages : 454

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Book Description
This volume represents edited material that was presented at a conference on brainstem modulation of spinal nociception held in Beaune, France during July, 1987. Pain Modulation, Volume 77 in the series Progress in Brain Research reviews, analyses and suggests new research strategies on several relevant topics including: the endogenous opioid peptides; sites of action of opiates; the role of biogenic animes and non-opioid peptides in analgesia; dorsal horn circuitry; behavioural factors in the activation of pain modulating networks and clinical studies of nociceptive modulation.

Author: Reginald Dean
Publisher: Springer Science & Business Media
ISBN: 1597451975
Category : Medical
Languages : en
Pages : 767

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Book Description
Comprehensive and authoritative, Opioid Receptors and Antagonists: From Bench to Clinic offers neuroscientists, pharmacologists and interested clinicians a unique survey of the extensive and diverse research efforts currently employed with opioid antagonists to develop novel innovative drug therapies. Summarizes the present understanding of the chemistry, pharmacology and molecular biology of opioid receptors and their subtypes Highlights differences and similarities between the opioid pharmacology of animals and human Describes current and potential therapeutic areas for opioid antagonists, including substance abuse, alcohol and ingestive behaviors, behavioral disorders and other medical indications, supported by nonclinical and clinical evidence Focuses on the development of exciting and innovative drug delivery approaches that are being used with opioid antagonists for the above medical indications