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Author: Publisher: Wiley ISBN: 9781118180037 Category : Medical Languages : en Pages : 0
Book Description
The ideal place to begin researching any question involving drug metabolism and interactions The Encyclopedia of Drug Metabolism and Interactions provides essential support during all phases of drug development, from drug design to drug action and interaction within the human body. This six-volume work covers both preclinical and clinical aspects of drug metabolism and interactions. It also provides a wealth of toxicological, regulatory, and marketing information, all written and edited by leading international experts in the field. By collecting and reviewing the current literature in the field in one expertly organized work, this encyclopedia is the ideal place to begin researching any question involving drug metabolism and interactions. Readers will find such important topics and working tools as: Inhibited or induced enzymes and their impact on drug toxicity and altered response in both animal and human models Effects of both genetic and non-genetic factors on drug metabolism Relationships between a drug metabolism, its activation or inactivation, and a drug's potential toxicity/safety Examples demonstrating all aspects of drug metabolism and interactions in silico, in vitro, in laboratory animals, and in humans Methods and protocols enabling readers to perform seamless studies of metabolism and drug interactions All articles are based on recent findings and standards of practice. By reviewing and contextualizing the current literature, the authors offer new perspectives on our current state of knowledge as well as future directions for research in drug metabolism and interactions. References at the end of each article serve as a gateway to the literature. The Encyclopedia of Drug Metabolism and Interactions is recommended for researchers, physicians, and students at all levels. It introduces the basics to novices and explores the latest science and applications for more experienced investigators.
Author: Publisher: Wiley ISBN: 9781118180037 Category : Medical Languages : en Pages : 0
Book Description
The ideal place to begin researching any question involving drug metabolism and interactions The Encyclopedia of Drug Metabolism and Interactions provides essential support during all phases of drug development, from drug design to drug action and interaction within the human body. This six-volume work covers both preclinical and clinical aspects of drug metabolism and interactions. It also provides a wealth of toxicological, regulatory, and marketing information, all written and edited by leading international experts in the field. By collecting and reviewing the current literature in the field in one expertly organized work, this encyclopedia is the ideal place to begin researching any question involving drug metabolism and interactions. Readers will find such important topics and working tools as: Inhibited or induced enzymes and their impact on drug toxicity and altered response in both animal and human models Effects of both genetic and non-genetic factors on drug metabolism Relationships between a drug metabolism, its activation or inactivation, and a drug's potential toxicity/safety Examples demonstrating all aspects of drug metabolism and interactions in silico, in vitro, in laboratory animals, and in humans Methods and protocols enabling readers to perform seamless studies of metabolism and drug interactions All articles are based on recent findings and standards of practice. By reviewing and contextualizing the current literature, the authors offer new perspectives on our current state of knowledge as well as future directions for research in drug metabolism and interactions. References at the end of each article serve as a gateway to the literature. The Encyclopedia of Drug Metabolism and Interactions is recommended for researchers, physicians, and students at all levels. It introduces the basics to novices and explores the latest science and applications for more experienced investigators.
Author: Publisher: Wiley ISBN: 9780470450154 Category : Medical Languages : en Pages : 0
Book Description
“This one-stop reference brings together information scattered throughout the literature, and it involved the efforts of 270 expert authors from 16 countries — a global endeavor accomplished under the leadership of editor Alexander Lyubimov.” –Book News Inc., February 2013 The Encyclopedia of Drug Metabolism and Interactions provides essential support during all phases of drug development, from drug design to drug action and interaction in patients. This multivolume work covers both preclinical and clinical aspects of drug metabolism and interactions. It also provides a wealth of toxicological, regulatory, and marketing information, all written by leading international experts in the field. Using this reference you’ll discover: • Enzymes that can be inhibited or induced and their impact on drug toxicity and altered response in both animal and human models • Effect of genetic differences and non-genetic factors on drug metabolism • Balance among drug metabolism, its inactivation/activation, and its potential toxicity • Examples demonstrating all aspects of drug metabolism and interactions in silico, in laboratory animals, and in humans • Methods and detailed protocols enabling you to perform seamless studies of metabolism and drug interactions This reference is essential for researchers interested in all aspects of drug development, and chemists, pharmacologists, pharmaceutical specialists, toxicologists, molecular toxicologists, and clinicians, including practitioners and physicians. Enjoy the Online Advantage... The Encyclopedia of Drug Metabolism and Interactions is available online now. For further information visit wileyonlinelibrary.com/ref/lyubimov
Author: Alexander Lyubimov Publisher: Anchor Books ISBN: 9781118149799 Category : Drug interactions Languages : en Pages : 808
Book Description
The ideal place to begin researching any question involving drug metabolism and interactions The Encyclopedia of Drug Metabolism and Interactions provides essential support during all phases of drug development, from drug design to drug action and interaction within the human body. This six-volume work covers both preclinical and clinical aspects of drug metabolism and interactions. It also provides a wealth of toxicological, regulatory, and marketing information, all written and edited by leading international experts in the field. By collecting and reviewing the current literature in the field in one expertly organized work, this encyclopedia is the ideal place to begin researching any question involving drug metabolism and interactions. Readers will find such important topics and working tools as: Inhibited or induced enzymes and their impact on drug toxicity and altered response in both animal and human models Effects of both genetic and non-genetic factors on drug metabolism Relationships between a drug metabolism, its activation or inactivation, and a drug's potential toxicity/safety Examples demonstrating all aspects of drug metabolism and interactions in silico, in vitro, in laboratory animals, and in humans Methods and protocols enabling readers to perform seamless studies of metabolism and drug interactions All articles are based on recent findings and standards of practice. By reviewing and contextualizing the current literature, the authors offer new perspectives on our current state of knowledge as well as future directions for research in drug metabolism and interactions. References at the end of each article serve as a gateway to the literature. The Encyclopedia of Drug Metabolism and Interactions is recommended for researchers, physicians, and students at all levels. It introduces the basics to novices and explores the latest science and applications for more experienced investigators.
Author: Publisher: Wiley ISBN: 9781118180013 Category : Medical Languages : en Pages : 836
Book Description
"This multi-volume encyclopedia discusses all preclinical, clinical, toxicological, regulatory and marketing perspectives of drug metabolism and interactions. The various types of enzymes that can be inhibited or induced and their impact on drug toxicity and altered response are covered both for animal models and humans"--Provided by publisher.
Author: Iris F. F. Benzie Publisher: CRC Press ISBN: 1439807167 Category : Health & Fitness Languages : en Pages : 500
Book Description
The global popularity of herbal supplements and the promise they hold in treating various disease states has caused an unprecedented interest in understanding the molecular basis of the biological activity of traditional remedies. Herbal Medicine: Biomolecular and Clinical Aspects focuses on presenting current scientific evidence of biomolecular ef
Author: Alan Talevi Publisher: Springer Nature ISBN: 3030848604 Category : Medical Languages : en Pages : 1209
Book Description
The ADME Encyclopedia covers pharmacokinetic phenomena (Absorption, Distribution, Metabolism and Excretion processes) and their relationship with the design of pharmaceutical carriers and the success of drug therapies. It covers both basic and advanced knowledge, serving as introductory material for students of biomedical careers and also as reference, updated material for graduates and professionals working in any field related to pharmaceutical sciences (medicine, pharmaceutical technology, materials science, medicinal chemistry). Structured as alphabetically ordered entries with cross-references, the Encyclopedia not only provides basic knowledge on ADME processes, but also detailed entries on some advanced subjects such as drug transporters, last generation pharmaceutical carriers, pharmacogenomics, personalized medicine, bioequivalence studies, biowaivers, biopharmaceuticals, gene delivery, pharmacometrics, pharmacokinetic drug interactions or in silico and in vitro assessment of ADME properties
Author: Publisher: Academic Press ISBN: 0123851580 Category : Medical Languages : en Pages : 4744
Book Description
The Encyclopedia of the Neurological Sciences, Second Edition, Four Volume Set develops from the first edition, covering all areas of neurological sciences through over 1000 entries focused on a wide variety of topics in neurology, neurosurgery, psychiatry and other related areas of neuroscience. The contributing authors represent all aspects of neurology from many viewpoints and disciplines to provide a complete overview of the field. Entries are designed to be understandable without detailed background knowledge in the subject matter, and cross-referencing and suggested further reading lead the reader from a basic knowledge of the subject to more advanced understanding. The easy-to-use 'encyclopedic-dictionary' format of the Encyclopedia of the Neurological Sciences, Second Edition features alphabetic entries, extensive cross-referencing, and a thorough index for quick reference. The wealth of information provided by these four volumes makes this reference work a trusted source of valuable information for a wide range of researchers, from undergraduate students to academic researchers. Provides comprehensive coverage of the field of neurological science in over 1,000 entries in 4 volumes "Encyclopedic-dictionary" format provides for concise, readable entries and easy searching Presents complete, up-to-date information on 32 separate areas of neurology Entries are supplemented with extensive cross-referencing, useful references to primary research articles, and an extensive index
Author: Publisher: Wiley ISBN: 9780470450154 Category : Medical Languages : en Pages : 4736
Book Description
“This one-stop reference brings together information scattered throughout the literature, and it involved the efforts of 270 expert authors from 16 countries — a global endeavor accomplished under the leadership of editor Alexander Lyubimov.” –Book News Inc., February 2013 The Encyclopedia of Drug Metabolism and Interactions provides essential support during all phases of drug development, from drug design to drug action and interaction in patients. This multivolume work covers both preclinical and clinical aspects of drug metabolism and interactions. It also provides a wealth of toxicological, regulatory, and marketing information, all written by leading international experts in the field. Using this reference you’ll discover: • Enzymes that can be inhibited or induced and their impact on drug toxicity and altered response in both animal and human models • Effect of genetic differences and non-genetic factors on drug metabolism • Balance among drug metabolism, its inactivation/activation, and its potential toxicity • Examples demonstrating all aspects of drug metabolism and interactions in silico, in laboratory animals, and in humans • Methods and detailed protocols enabling you to perform seamless studies of metabolism and drug interactions This reference is essential for researchers interested in all aspects of drug development, and chemists, pharmacologists, pharmaceutical specialists, toxicologists, molecular toxicologists, and clinicians, including practitioners and physicians. Enjoy the Online Advantage... The Encyclopedia of Drug Metabolism and Interactions is available online now. For further information visit wileyonlinelibrary.com/ref/lyubimov
Author: Pablo Muriel Publisher: Academic Press ISBN: 0128043210 Category : Science Languages : en Pages : 917
Book Description
Liver Pathophysiology: Therapies and Antioxidants is a complete volume on morphology, physiology, biochemistry, molecular biology and treatment of liver diseases. It uses an integral approach towards the role of free radicals in the pathogenesis of hepatic injury, and how their deleterious effects may be abrogated by the use of antioxidants. Written by the most prominent authors in the field, this book will be of use to basic and clinical scientists and clinicians working in the biological sciences, especially those dedicated to the study and treatment of liver pathologies. Presents the most recent advances in hepatology, with a special focus on the role of oxidative stress in liver injury. Provides in vivo and in vitro models to study human liver pathology. Explains the beneficial effects of antioxidants on liver diseases. Contains the most recent and modern treatments of hepatic pathologies, including, but not limited to, stem cells repopulation, gene therapy and liver transplantation.
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Author: Alexander Lyubimov
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Author: Iris F. F. Benzie
Author: Alan Talevi
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Author: Pablo Muriel
Author: L. Meyler