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Empirical Bayes Methods with Applications

Empirical Bayes Methods with Applications PDF Author: J.S. Maritz
Publisher: CRC Press
ISBN: 1351080113
Category : Mathematics
Languages : en
Pages : 296

Book Description
The second edition of Empirical Bayes Methods details are provided of the derivation and the performance of empirical Bayes rules for a variety of special models. Attention is given to the problem of assessing the goodness of an empirical Bayes estimator for a given set of prior data. A chapter is devoted to a discussion of alternatives to the empirical Bayes approach and there is also a chapter giving details of several actual applications of empirical Bayes method.

Empirical Bayes Methods with Applications

Empirical Bayes Methods with Applications PDF Author: J.S. Maritz
Publisher: CRC Press
ISBN: 1351088564
Category : Mathematics
Languages : en
Pages : 360

Book Description
The second edition of Empirical Bayes Methods details are provided of the derivation and the performance of empirical Bayes rules for a variety of special models. Attention is given to the problem of assessing the goodness of an empirical Bayes estimator for a given set of prior data. A chapter is devoted to a discussion of alternatives to the empirical Bayes approach and there is also a chapter giving details of several actual applications of empirical Bayes method.

Empirical Bayes Methods

Empirical Bayes Methods PDF Author: J. S. Maritz
Publisher:
ISBN:
Category : Mathematics
Languages : en
Pages : 176

Book Description


Revisiting Empirical Bayes Methods and Applications to Special Types of Data

Revisiting Empirical Bayes Methods and Applications to Special Types of Data PDF Author: Xiuwen Duan
Publisher:
ISBN:
Category :
Languages : en
Pages :

Book Description
Empirical Bayes methods have been around for a long time and have a wide range of applications. These methods provide a way in which historical data can be aggregated to provide estimates of the posterior mean. This thesis revisits some of the empirical Bayesian methods and develops new applications. We first look at a linear empirical Bayes estimator and apply it on ranking and symbolic data. Next, we consider Tweedie's formula and show how it can be applied to analyze a microarray dataset. The application of the formula is simplified with the Pearson system of distributions. Saddlepoint approximations enable us to generalize several results in this direction. The results show that the proposed methods perform well in applications to real data sets.

Large-Scale Inference

Large-Scale Inference PDF Author: Bradley Efron
Publisher: Cambridge University Press
ISBN: 1139492136
Category : Mathematics
Languages : en
Pages :

Book Description
We live in a new age for statistical inference, where modern scientific technology such as microarrays and fMRI machines routinely produce thousands and sometimes millions of parallel data sets, each with its own estimation or testing problem. Doing thousands of problems at once is more than repeated application of classical methods. Taking an empirical Bayes approach, Bradley Efron, inventor of the bootstrap, shows how information accrues across problems in a way that combines Bayesian and frequentist ideas. Estimation, testing and prediction blend in this framework, producing opportunities for new methodologies of increased power. New difficulties also arise, easily leading to flawed inferences. This book takes a careful look at both the promise and pitfalls of large-scale statistical inference, with particular attention to false discovery rates, the most successful of the new statistical techniques. Emphasis is on the inferential ideas underlying technical developments, illustrated using a large number of real examples.

Empirical Bayes and Likelihood Inference

Empirical Bayes and Likelihood Inference PDF Author: S.E. Ahmed
Publisher: Springer Science & Business Media
ISBN: 9780387950181
Category : Mathematics
Languages : en
Pages : 260

Book Description
Bayesian and such approaches to inference have a number of points of close contact, especially from an asymptotic point of view. Both emphasize the construction of interval estimates of unknown parameters. In this volume, researchers present recent work on several aspects of Bayesian, likelihood and empirical Bayes methods, presented at a workshop held in Montreal, Canada. The goal of the workshop was to explore the linkages among the methods, and to suggest new directions for research in the theory of inference.

Large-scale Inference

Large-scale Inference PDF Author: Bradley Efron
Publisher:
ISBN: 9780511918575
Category : Mathematics
Languages : en
Pages : 263

Book Description
We live in a new age for statistical inference, where modern scientific technology such as microarrays and fMRI machines routinely produce thousands and sometimes millions of parallel data sets, each with its own estimation or testing problem. Doing thousands of problems at once is more than repeated application of classical methods. Taking an empirical Bayes approach, Bradley Efron, inventor of the bootstrap, shows how information accrues across problems in a way that combines Bayesian and frequentist ideas. Estimation, testing and prediction blend in this framework, producing opportunities for new methodologies of increased power. New difficulties also arise, easily leading to flawed inferences. This book takes a careful look at both the promise and pitfalls of large-scale statistical inference, with particular attention to false discovery rates, the most successful of the new statistical techniques. Emphasis is on the inferential ideas underlying technical developments, illustrated using a large number of real examples.

Current Trends in Bayesian Methodology with Applications

Current Trends in Bayesian Methodology with Applications PDF Author: Satyanshu K. Upadhyay
Publisher: CRC Press
ISBN: 1482235129
Category : Mathematics
Languages : en
Pages : 674

Book Description
Collecting Bayesian material scattered throughout the literature, Current Trends in Bayesian Methodology with Applications examines the latest methodological and applied aspects of Bayesian statistics. The book covers biostatistics, econometrics, reliability and risk analysis, spatial statistics, image analysis, shape analysis, Bayesian computation, clustering, uncertainty assessment, high-energy astrophysics, neural networking, fuzzy information, objective Bayesian methodologies, empirical Bayes methods, small area estimation, and many more topics. Each chapter is self-contained and focuses on a Bayesian methodology. It gives an overview of the area, presents theoretical insights, and emphasizes applications through motivating examples. This book reflects the diversity of Bayesian analysis, from novel Bayesian methodology, such as nonignorable response and factor analysis, to state-of-the-art applications in economics, astrophysics, biomedicine, oceanography, and other areas. It guides readers in using Bayesian techniques for a range of statistical analyses.

Bayesian Methods for Data Analysis, Third Edition

Bayesian Methods for Data Analysis, Third Edition PDF Author: Bradley P. Carlin
Publisher: CRC Press
ISBN: 9781584886983
Category : Mathematics
Languages : en
Pages : 552

Book Description
Broadening its scope to nonstatisticians, Bayesian Methods for Data Analysis, Third Edition provides an accessible introduction to the foundations and applications of Bayesian analysis. Along with a complete reorganization of the material, this edition concentrates more on hierarchical Bayesian modeling as implemented via Markov chain Monte Carlo (MCMC) methods and related data analytic techniques. New to the Third Edition New data examples, corresponding R and WinBUGS code, and homework problems Explicit descriptions and illustrations of hierarchical modeling—now commonplace in Bayesian data analysis A new chapter on Bayesian design that emphasizes Bayesian clinical trials A completely revised and expanded section on ranking and histogram estimation A new case study on infectious disease modeling and the 1918 flu epidemic A solutions manual for qualifying instructors that contains solutions, computer code, and associated output for every homework problem—available both electronically and in print Ideal for Anyone Performing Statistical Analyses Focusing on applications from biostatistics, epidemiology, and medicine, this text builds on the popularity of its predecessors by making it suitable for even more practitioners and students.

Bayes and Empirical Bayes Methods for Data Analysis

Bayes and Empirical Bayes Methods for Data Analysis PDF Author: Bradley P. Carlin
Publisher:
ISBN:
Category : Analysis of variance
Languages : en
Pages : 399

Book Description


Genomics Data Analysis

Genomics Data Analysis PDF Author: David R. Bickel
Publisher: CRC Press
ISBN: 1000706915
Category : Mathematics
Languages : en
Pages : 141

Book Description
Statisticians have met the need to test hundreds or thousands of genomics hypotheses simultaneously with novel empirical Bayes methods that combine advantages of traditional Bayesian and frequentist statistics. Techniques for estimating the local false discovery rate assign probabilities of differential gene expression, genetic association, etc. without requiring subjective prior distributions. This book brings these methods to scientists while keeping the mathematics at an elementary level. Readers will learn the fundamental concepts behind local false discovery rates, preparing them to analyze their own genomics data and to critically evaluate published genomics research. Key Features: * dice games and exercises, including one using interactive software, for teaching the concepts in the classroom * examples focusing on gene expression and on genetic association data and briefly covering metabolomics data and proteomics data * gradual introduction to the mathematical equations needed * how to choose between different methods of multiple hypothesis testing * how to convert the output of genomics hypothesis testing software to estimates of local false discovery rates * guidance through the minefield of current criticisms of p values * material on non-Bayesian prior p values and posterior p values not previously published