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Author: Pierre Capy Publisher: Springer Science & Business Media ISBN: 9780792346906 Category : Science Languages : en Pages : 366
Book Description
During the last 50 years, the perception oftransposable elements (TEs) has changed considerably from selfish DNA to sequences that may contribute significantly to genome function and evolution. The recent increased interest in TEs is based on the realization that they are a major genetic component (at least 10--20%) of all organisms and a major contributor to the mutation process. It is currently estimated that 70--80% of spontaneous mutations are the result of TE-mediated insertions, deletions, or chromosomal rearrangements. Thus, it seems at least plausible that TEs may playa significant role in the adaptation and evolution of natural populations and species. The ubiquity of TEs suggests that they are an old component of genomes which have been vertically transmitted through generations over evolutionary time. However, detailed analyses carried out over the last 20 years have revealed several unusual features of TE evolution: (i) TEs can be horizontally transferred between species; (ii) TE evolutionary rates can be dramatically increased by specific inactivation processes, such as the RIP (Repeat Induced Point mutation) mechanism in fungi; (iii) TEs can influence the regulation of other TEs by insertion or deletion; (iv) different classes of TEs in even distantly related species can be remarkably similar in both structure and function.
Author: Pierre Capy Publisher: Springer Science & Business Media ISBN: 9780792346906 Category : Science Languages : en Pages : 366
Book Description
During the last 50 years, the perception oftransposable elements (TEs) has changed considerably from selfish DNA to sequences that may contribute significantly to genome function and evolution. The recent increased interest in TEs is based on the realization that they are a major genetic component (at least 10--20%) of all organisms and a major contributor to the mutation process. It is currently estimated that 70--80% of spontaneous mutations are the result of TE-mediated insertions, deletions, or chromosomal rearrangements. Thus, it seems at least plausible that TEs may playa significant role in the adaptation and evolution of natural populations and species. The ubiquity of TEs suggests that they are an old component of genomes which have been vertically transmitted through generations over evolutionary time. However, detailed analyses carried out over the last 20 years have revealed several unusual features of TE evolution: (i) TEs can be horizontally transferred between species; (ii) TE evolutionary rates can be dramatically increased by specific inactivation processes, such as the RIP (Repeat Induced Point mutation) mechanism in fungi; (iii) TEs can influence the regulation of other TEs by insertion or deletion; (iv) different classes of TEs in even distantly related species can be remarkably similar in both structure and function.
Author: W.R. Knorr Publisher: Springer Science & Business Media ISBN: 9789027705099 Category : Mathematics Languages : en Pages : 402
Book Description
The present work has three principal objectives: (1) to fix the chronology of the development of the pre-Euclidean theory of incommensurable magnitudes beginning from the first discoveries by fifth-century Pythago reans, advancing through the achievements of Theodorus of Cyrene, Theaetetus, Archytas and Eudoxus, and culminating in the formal theory of Elements X; (2) to correlate the stages of this developing theory with the evolution of the Elements as a whole; and (3) to establish that the high standards of rigor characteristic of this evolution were intrinsic to the mathematicians' work. In this third point, we wish to counterbalance a prevalent thesis that the impulse toward mathematical rigor was purely a response to the dialecticians' critique of foundations; on the contrary, we shall see that not until Eudoxus does there appear work which may be described as purely foundational in its intent. Through the examination of these problems, the present work will either alter or set in a new light virtually every standard thesis about the fourth-century Greek geometry. I. THE PRE-EUCLIDEAN THEORY OF INCOMMENSURABLE MAGNITUDES The Euclidean theory of incommensurable magnitudes, as preserved in Book X of the Elements, is a synthetic masterwork. Yet there are detect able seams in its structure, seams revealed both through terminology and through the historical clues provided by the neo-Platonist commentator Proclus.
Author: Stephen Finney Mason Publisher: Oxford University Press, USA ISBN: Category : Language Arts & Disciplines Languages : en Pages : 344
Book Description
This fascinating survey takes chemistry as the central science of all materials at the molecular level, and brings together both organic and inorganic aspects in a clear account of the development of ideas of chemical evolution.
Author: Bernd Markert Publisher: Springer ISBN: 3319143557 Category : Science Languages : en Pages : 295
Book Description
This book is written for researchers and students interested in the function and role of chemical elements in biological or environmental systems. Experts have long known that the Periodic System of Elements (PSE) provides only an inadequate chemical description of elements of biological, environmental or medicinal importance. This book explores the notion of a Biological System of the Elements (BSE) established on accurate and precise multi-element data, including evolutionary aspects, representative sampling procedures, inter-element relationships, the physiological function of elements and uptake mechanisms. The book further explores the concept Stoichiometric Network Analysis (SNA) to analyze the biological roles of chemical species. Also discussed is the idea of ecotoxicological identity cards which give a first-hand description of properties relevant for biological and toxicological features of a certain chemical element and its geo biochemically plausible speciation form. The focus of this book goes beyond both classical bioinorganic chemistry and toxicology.
Author: J. F. McDonald Publisher: Springer Science & Business Media ISBN: 9780792363064 Category : Medical Languages : en Pages : 314
Book Description
Once considered merely `selfish' or `parasitic' DNA, transposable elements are today recognized as being of major biological significance. Not only are these elements a major source of mutation, they have contributed both directly and indirectly to the evolution of genome structure and function. On October 8-10, 1999, 100 molecular biologists and evolutionists representing 11 countries met on the campus of The University of Georgia in Athens for the inaugural Georgia Genetics Symposium. The topics of presentations ranged from how the elements themselves have evolved to the impact transposable elements have had on the evolution of their host genomes. The papers in this volume therefore represent state-of-the-art thinking, by leading world experts in the field, on the evolutionary significance of transposable elements.
Author: J. Arvid Ågren Publisher: Oxford University Press ISBN: 0198862261 Category : Science Languages : en Pages : 257
Book Description
"To many evolutionary biologists, the central challenge of their discipline is to explain adaptation, the appearance of design in the living world. With the theory of evolution by natural selection, Charles Darwin elegantly showed how a purely mechanistic process can achieve this striking feature of nature. Since then, the way many biologists have thought about evolution and natural selection is as a theory about individual organisms. Over a century later, a subtle but radical shift in perspective emerged with the gene's-eye view of evolution in which natural selection was conceptualized as a struggle between genes for replication and transmission to the next generation. This viewpoint culminated with the publication of The Selfish Gene by Richard Dawkins (Oxford University Press, 1976) and is now commonly referred to as selfish gene thinking. The gene's-eye view has subsequently played a central role in evolutionary biology, although it continues to attract controversy. The central aim of this accessible book is to show how the gene's-eye view differs from the traditional organismal account of evolution, trace its historical origins, clarify typical misunderstandings and, by using examples from contemporary experimental work, show why so many evolutionary biologists still consider it an indispensable heuristic. The book concludes by discussing how selfish gene thinking fits into ongoing debates in evolutionary biology, and what they tell us about the future of the gene's-eye view of evolution."--
Author: Design Associates Chen Publisher: Simon and Schuster ISBN: 1440320802 Category : Design Languages : en Pages : 223
Book Description
For many designers, creating things by hand is a reaction to too much computer-based design. Since the first Fingerprint was published, ideas that were once on the fringe have begun to thrive in the mainstream. From typography and illustration to book-making and film titles, elements of handcraft have soaked into everyday life. Fingerprint No. 2 reflects the evolution of those ideas. In this second volume, you’ll still find plenty of projects created entirely without the aid of computer technology. But you’ll also discover how designers are beginning to incorporate the two aesthetics—handmade and digital—in order to best communicate their message. A third, hybrid aesthetic is emerging, one that marries the technologies of the past and future into a vibrant, exciting present. Look inside to discover 133 projects and exclusive visual essays from leading designers, including Robynne Raye, Stefan Bucher and Christian Helms. These pieces of work prove that handmade elements are not only vital to excellent design, but often result in exceptional design. Listen for the pulse, which cannot be faked, forged, or falsified. Look for the finger print. It is the key to design’s success.
Author: National Academy of Sciences Publisher: ISBN: Category : Science Languages : en Pages : 388
Book Description
The Arthur M. Sackler Colloquia of the National Academy of Sciences address scientific topics of broad and current interest, cutting across the boundaries of traditional disciplines. Each year, four or five such colloquia are scheduled, typically two days in length and international in scope. Colloquia are organized by a member of the Academy, often with the assistance of an organizing committee, and feature presentations by leading scientists in the field and discussions with a hundred or more researchers with an interest in the topic. Colloquia presentations are recorded and posted on the National Academy of Sciences Sackler colloquia website and published on CD-ROM. These Colloquia are made possible by a generous gift from Mrs. Jill Sackler, in memory of her husband, Arthur M. Sackler.
Author: Michael Chandler Publisher: John Wiley & Sons ISBN: 1555819214 Category : Science Languages : en Pages : 1347
Book Description
An exploration of the raw power of genetic material to refashion itself to any purpose... Virtually all organisms contain multiple mobile DNAs that can move from place to place, and in some organisms, mobile DNA elements make up a significant portion of the genome. Mobile DNA III provides a comprehensive review of recent research, including findings suggesting the important role that mobile elements play in genome evolution and stability. Editor-in-Chief Nancy L. Craig assembled a team of multidisciplinary experts to develop this cutting-edge resource that covers the specific molecular mechanisms involved in recombination, including a detailed structural analysis of the enzymes responsible presents a detailed account of the many different recombination systems that can rearrange genomes examines the tremendous impact of mobile DNA in virtually all organisms Mobile DNA III is valuable as an in-depth supplemental reading for upper level life sciences students and as a reference for investigators exploring new biological systems. Biomedical researchers will find documentation of recent advances in understanding immune-antigen conflict between host and pathogen. It introduces biotechnicians to amazing tools for in vivo control of designer DNAs. It allows specialists to pick and choose advanced reviews of specific elements and to be drawn in by unexpected parallels and contrasts among the elements in diverse organisms. Mobile DNA III provides the most lucid reviews of these complex topics available anywhere.
Author: J. F. McDonald Publisher: Springer Science & Business Media ISBN: 9401120285 Category : Medical Languages : en Pages : 355
Book Description
In the summer of 1992 a distinguished group of molecular, population and evolutionary geneticists assembled on the campus of the University of Georgia in Athens, USA to discuss the relevance of their research to the role played by transposable elements (TEs) in evolution. The meeting consisted of a series of informal discussions of issues brought up in papers written by the participants and distributed among them prior to the meeting. These papers and the transcripts of the ensuing discussions are presented in this volume.
Author: Pierre Capy
Author: Pierre Capy
Author: W.R. Knorr
Author: Stephen Finney Mason
Author: Bernd Markert
Author: J. F. McDonald
Author: J. Arvid Ågren
Author: Design Associates Chen
Author: National Academy of Sciences
Author: Michael Chandler
Author: J. F. McDonald