Electrophysiological Analysis of Synaptic Transmission PDF Download

Author: Nicholas Graziane
Publisher: Springer Nature
ISBN: 1071625896
Category : Medical
Languages : en
Pages : 283

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Book Description
This second edition volume expands on the previous edition with discussions on the latest techniques used to study synaptic transmissions. The chapters in this book are organized into six parts. Part One looks at the basic concepts, such as extracellular and intracellular recordings, and spatiotemporal effects of synaptic currents. Part Two describes the recording of synaptic currents, such as measuring kinetics of synaptic current and measuring reversal potentials. Part Three discusses basic experimentations of synaptic transmission and covers run-up and run-down, and amplitude. Parts Four and Five cover experimentations with computational components and molecular and visual components, such as measurement of a single synapse and electrophysiological and visual tags. Part Six explores in vivo recordings and talks about general considerations for in vivo exploration of synaptic plasticity. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Authoritative and thorough, Electrophysiological Analysis of Synaptic Transmission, Second Edition is a valuable resource that introduces graduate students and postdoctoral fellows to important topics in this field and also expands these topics to practical electrophysiological approaches.

Author: John I. Hubbard
Publisher:
ISBN:
Category : Electrophysiology
Languages : en
Pages : 390

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Book Description

Author: John I. Hubbard
Publisher: Hodder Education
ISBN:
Category : Medical
Languages : en
Pages : 444

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Book Description

Author: Neurosciences Institute (New York, N.Y.)
Publisher: Wiley-Interscience
ISBN:
Category : Medical
Languages : en
Pages : 808

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Book Description
This book consists of five sections. The first section details methods for analyzing both presynaptic and postsynaptic function and emphasizes the molecular aspects of synapses. It describes ongoing studies of neurotransmitter release, voltage- sensitive ion channels, and electronic transmission at gap junctions. The second section focuses on the growing menagerie of neurotransmitters: their catagorization into chemical families, their relation to ion channels, their modulation by second messenger systems and their role in pharmacologic action. The third section considers the important relationship of transmitter diversity and synaptic types to the behavior of actual cellular networks. All of the studies described in these sections point to the necessity of considering interactions between anatomy, chemistry, physiology and pharmacology if synaptic function is to be understood at any one of these levels of analysis.

Author: Hugo J. Bellen
Publisher: Oxford University Press, USA
ISBN:
Category : Medical
Languages : en
Pages : 466

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Book Description
This book provides the reader with background information on neurotransmitter release. Emphasis is placed on the rationale by which proteins are assigned specific functions rather than just providing facts about function.

Author: Rodolfo Riascos Llinás
Publisher:
ISBN: 9780195116526
Category : Medical
Languages : en
Pages : 234

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Book Description
The squid giant synapse is the single most important model for investigating the transmitter release mechanism in chemical junctions. This unique book, by a leading expert in the field, gives a concise overview of all that has been learned about synaptic transmission in this superb model system. It covers in detail the biophysics of the voltage-dependent calcium currents, calcium concentration microdomains, and much of the molecular basis for the triggering of the secretory event. Ideal for graduate and undergraduate courses, the book includes PC and Macintosh versions of two programs for simulating and manipulating any aspect of synaptic transmission. One program is a modeling tool designed for working neuroscientists, and the other teaches the basic principles of synaptic transmission by allowing students to alter the parameters, essentially without limits, and see the effects on the action potential over time. Anyone studying this central topic of neuroscience will find this book an invaluable resource.

Author: Jeffrey Noebels
Publisher: OUP USA
ISBN: 0199746540
Category : Medical
Languages : en
Pages : 1258

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Book Description
Jasper's Basic Mechanisms, Fourth Edition, is the newest most ambitious and now clinically relevant publishing project to build on the four-decade legacy of the Jasper's series. In keeping with the original goal of searching for "a better understanding of the epilepsies and rational methods of prevention and treatment.", the book represents an encyclopedic compendium neurobiological mechanisms of seizures, epileptogenesis, epilepsy genetics and comordid conditions. Of practical importance to the clinician, and new to this edition are disease mechanisms of genetic epilepsies and therapeutic approaches, ranging from novel antiepileptic drug targets to cell and gene therapies.

Author: Thomas C. Südhof
Publisher: Springer Science & Business Media
ISBN: 3540748059
Category : Medical
Languages : en
Pages : 582

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Book Description
It has been known for half a century that neurotransmitters are released in preformed quanta, that the quanta represent transmitter-storing vesicles, and that release occurs by exocytosis. The focus of this book is twofold. In the first part, the molecular events of exocytosis are analysed. In the second part of the book, the presynaptic receptors for endogenous chemical signals are presented that make neurotransmitter release a highly regulated process.

Author: R. Wayne Albers
Publisher: Academic Press
ISBN: 0080959016
Category : Science
Languages : en
Pages : 1121

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Book Description
Basic Neurochemistry, Eighth Edition, is the updated version of the outstanding and comprehensive classic text on neurochemistry. For more than forty years, this text has been the worldwide standard for information on the biochemistry of the nervous system, serving as a resource for postgraduate trainees and teachers in neurology, psychiatry, and basic neuroscience, as well as for medical, graduate, and postgraduate students and instructors in the neurosciences. The text has evolved, as intended, with the science. This new edition continues to cover the basics of neurochemistry as in the earlier editions, along with expanded and additional coverage of new research from intracellular trafficking, stem cells, adult neurogenesis, regeneration, and lipid messengers. It contains expanded coverage of all major neurodegenerative and psychiatric disorders, including the neurochemistry of addiction, pain, and hearing and balance; the neurobiology of learning and memory; sleep; myelin structure, development, and disease; autism; and neuroimmunology. - Completely updated text with new authors and material, and many entirely new chapters - Over 400 fully revised figures in splendid color - 61 chapters covering the range of cellular, molecular and medical neuroscience - Translational science boxes emphasizing the connections between basic and clinical neuroscience - Companion website at http://elsevierdirect.com/companions/9780123749475

Author: A.G. Brown
Publisher: Springer Science & Business Media
ISBN: 9783540760900
Category : Medical
Languages : en
Pages : 276

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Book Description
It is now about 10 years since the first edition of Nerve Cells and Nervous Systems was published. There have been many important advances across the whole field of neuro science since 1990 and it was obvious that the first edition had become much less useful than when it was published. Hence this new edition. I have attempted to keep to the aims of the first edition by presenting the general principles of neuroscience in the context of experimental evidence. As with the first edition, the selection of material to include, or exclude, has been difficult and invariably reflects my personal biases. I hope that not too many readers will be disappointed with the selections. I have unashamedly retained material, and, in particular, illustrations where I think they remain of importance to an understanding of the field and to its historical development. As before, I have attempted as reasonable a coverage as possible within the confines of a book that should be easy to carry around, to handle and, I hope, to read. The book should be useful for anyone studying the nervous system at both undergraduate and immediate postgraduate levels. In particular, under graduates reading neuroscience or any course containing a neuroscience component, such as physiology, pharmacology, biomedical sciences or psychology, as well as medicine and veterinary medicine should find the book helpful.