Electrochemistry of Nucleic Acids and Proteins PDF Download

Author: E. Palecek
Publisher: Elsevier
ISBN: 0080457452
Category : Science
Languages : en
Pages : 809

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Book Description
DNA (sometimes referred to as the molecule of life), is the most interesting and most important of all molecules. Electrochemistry of Nucleic Acids and Proteins: Towards Electrochemical Sensors for Genomics and Proteomics is devoted to the electrochemistry of DNA and RNA and to the development of sensors for detecting DNA damage and DNA hybridization. Volume 1, in the brand new series Perspectives in Bioanalysis, looks at the electroanalytical chemistry of nucleic acids and proteins, development of electrochemical sensors and their application in biomedicine and in the new fields of genomics and proteomics. The authors have expertly formatted the information for a wide variety of readers, including new developments that will inspire students and young scientists to create new tools for science and medicine in the 21st century. * Covers highly sophisticated methods of electrochemical analysis of nucleic acids and proteins * Summarises the present state of electrochemical analysis of nucleic acids and proteins * Includes future trends in the electrochemical analysis in genomics and proteomics

Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 172

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Book Description

Author: Mehmet Sengun Ozsoz
Publisher: CRC Press
ISBN: 9814241776
Category : Science
Languages : en
Pages : 568

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Book Description
This book focuses on the basic electrochemical applications of DNA in various areas, from basic principles to the most recent discoveries. The book comprises theoretical and experimental analysis of various properties of nucleic acids, research methods, and some promising applications. The topics discussed in the book include electrochemical detection of DNA hybridization based on latex/gold nanoparticle and nanotubes; nanomaterial-based electrochemical DNA detection; electrochemical detection of microorganism-based DNA biosensors; gold nanoparticle-based electrochemical DNA biosensors; electrochemical detection of the aptamer-target interaction; nanoparticle-induced catalysis for DNA biosensing; basic terms regarding electrochemical DNA (nucleic acids) biosensors; screen-printed electrodes for electrochemical DNA detection; application of field-effect transistors to label free electrical DNA biosensor arrays; and electrochemical detection of nucleic acids using branched DNA amplifiers.

Author: Ali A. Ensafi
Publisher: Elsevier
ISBN: 0128164921
Category : Science
Languages : en
Pages : 388

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Book Description
Electrochemical Biosensors summarizes fundamentals and trends in electrochemical biosensing. It introduces readers to the principles of transducing biological information to measurable electrical signals to identify and quantify organic and inorganic substances in samples. The complexity of devices related to biological matrices makes this challenging, but this measurement and analysis are critically valuable in biotechnology and medicine. Electrochemical biosensors combine the sensitivity of electroanalytical methods with the inherent bioselectivity of the biological component. Some of these sensor devices have reached the commercial stage and are routinely used in clinical, environmental, industrial and agricultural applications. Describes several electrochemical methods used as detection techniques with biosensors Discusses different modifiers, including nanomaterials, for preparing suitable pathways for immobilizing biomaterials at the sensor Explains various types of signal monitoring, along with several recognition systems, including antibodies/antigens, DNA-based biosensors, aptamers (protein-based), and more

Author: Miroslav Fojta
Publisher: Springer
ISBN: 9783540699316
Category : Science
Languages : en
Pages : 350

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Book Description
This first monograph dedicated to the electrochemistry of nucleic acids offers complete coverage of the field. Modern electrochemical methods, in connection with different electrode types, are able to detect DNA, RNA or their synthetics analogues at attomole or even lower levels. In recent years, significant progress was achieved in the development of electrochemical techniques and sensors for DNA hybridization, DNA damage, interactions of nucleic acids with drugs, genotoxic species and other small molecules, as well as DNA-protein interactions. These sensors are expected to become important tools in biomedicine and other areas of practical life of the 21st century. Here, the authors describe the necessary experimental setup for electrochemical studies of nucleic acids, the properties and behavior of nucleic acids at electrode surfaces as well as the analytical applications of nucleic acid electrochemistry. All this information is presented with numerous worked examples and color figures.

Author: Frank-Michael Matysik
Publisher: Springer
ISBN: 3319484850
Category : Science
Languages : en
Pages : 348

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Book Description
This volume offers a careful selection of trend-setting topics in the field. In-depth review articles illustrate current trends in the field. Experienced experts present a comprehensive overview concerning the electrochemical biosensing of glucose for diabetes care from an industrial research and development perspective a survey of bioassay applications for individually addressable electrochemical arrays, focusing on liquid-phase bioanalytical assays a review of recent advances in the development of electronic tongues based on the use of biosensor arrays coupled with advanced chemometric data analysis novel strategies of DNA biosensor development and corresponding applications for studies of DNA damage a survey of recent trends in the electrochemistry of redox proteins, including the increasing diversity of redox proteins used in electrochemical studies, novel immobilization strategies, and biosensor / biofuel cell applications an overview of electrochemical sensing of blood gases with advanced sensor concepts a survey of recent bioelectroanalytical studies with high spatial resolution using scanning electrochemical microscopy with a wide range of applications covering imaging of living cells, studies of metabolic activity, imaging of local enzyme activity, and studies of transport through biolayers This timely collection will be of interest not only for experts in the field, but also to students and their teachers in disciplines that include analytical chemistry, biology, electrochemistry, and various interdisciplinary research areas.

Author: E. Palecek
Publisher: Elsevier
ISBN: 044452150X
Category : Science
Languages : en
Pages : 809

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Book Description
"This book is concerned with the electron transfer between electrodes on one hand and DNA, RNA and proteins on the other hand and with the use of electrochemistry and electrochemical sensors in DNA and protein analyses. Electrochemical bioassays involve newly emerging fields of genomic, proteomics, biomedicine and biotechnology. DNA and protein chips with electrochemical detection represent new tools of science, medicine and other areas of practical life in this century."--BOOK JACKET.

Author: Serge Cosnier
Publisher: CRC Press
ISBN: 9814411477
Category : Science
Languages : en
Pages : 405

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Book Description
Since four decades, rapid detection and monitoring in clinical and food diagnostics and in environmental and biodefense have paved the way for the elaboration of electrochemical biosensors. Thanks to their adaptability, ease of use in relatively complex samples, and their portability, electrochemical biosensors now are one of the mainstays of analy

Author: Navanita Sarma
Publisher:
ISBN:
Category : Bioelectrochemistry
Languages : en
Pages : 0

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Book Description
The research objective of this thesis was to develop aptamer (nucleic acid receptor) -based electrochemical sensors for molecular analytes that are of biomedical importance. Three different experimental approaches for the characterization of DNA-modified surfaces have been explored. First, cyclic voltammetric (CV) responses of redox cations, such as [Ru(NH3)6]3+, were analyzed to monitor the binding of lysozyme to aptamer-modified gold electrodes. It has been found that the decrease in the integrated charge of the electrostatically bound [Ru(NH3)6]3+ is proportional to the analyte concentration. The second part of the thesis briefly describes the application of an intercalator, 9,10-anthraquinone-2,6-disulfonic acid, as an alternative redox label for studying DNA-modified surfaces. The last part describes the synthesis and characterization of ferrocene tethered oligonucleotides (Fc-DNA). The electrochemical behavior of gold electrodes modified with Fc-DNA-strands has been evaluated.

Author:
Publisher: BoD – Books on Demand
ISBN: 1839624310
Category : Medical
Languages : en
Pages : 256

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Book Description
This book covers novel and current strategies for biosensing, from the use of nanomaterials and biological functionalized surfaces to the mathematical assessment of novel biosensors and their potential use as wearable devices for continuous monitoring. Biosensing technologies can be used in the medical field for the early detection of disease, monitoring effectiveness of treatments, detecting nervous system signals for controlling robotic prosthesis, and much more. This book includes eleven chapters that examine and discuss several strategies of biosensing, proposing mathematical designs that address the latest reported technologies.