Ehlers-Danlos syndrome: From bedside to bench PDF Download

Author: Tomoki Kosho
Publisher: Frontiers Media SA
ISBN: 2832545572
Category : Science
Languages : en
Pages : 105

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Author: Kelly M. Cordoro
Publisher: Elsevier Health Sciences
ISBN: 0323897398
Category : Medical
Languages : en
Pages : 129

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In this issue of Dermatologic Clinics, Guest Editor Kelly M. Cordoro brings considerable expertise to the topic of Pediatric Dermatology. Top experts in the field cover key topics such as Epidermal Nevi in Children, Pigmented Lesions in Children, Normal Skin Findings in Pediatric Patients with Skin of Color, and more. - Provides in-depth, clinical reviews on pediatric dermatology, providing actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field; Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews. - Contains 11 relevant, practice-oriented topics including Presentation of common skin disorders in pediatric patients with skin of color; Tips, Tricks and Pearls to Expertly Treating Common Skin Conditions in Pediatric Patients; Climate and Environmental Health as it Relates to Pediatric Dermatology; and more.

Author: Susmita Chowdhuri
Publisher: CRC Press
ISBN: 1000573273
Category : Medical
Languages : en
Pages : 497

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This book describes control of ventilation during sleep in both health and disease states. The topics are presented in a fashion that can be easily comprehended with many figures to illustrate complex concepts. Thus, a wide range of topics, starting from the site of normal respiratory rhythm generation to chemoreceptor control of sleep apnea, description of the apneic threshold, pathophysiology of upper airway closure, novel techniques to measure control of breathing, effect of cerebral blood flow on breathing, effect of opioids on ventilation, effect of heart failure on ventilation, genetic aspects of breathing disorders, age and gender differences, and various therapies are discussed. Key Features • Helps to bridge the gap between straight forward physiology and clinical practice through a range of topics and use of case vignettes • Explores various aspects of clinical management and control which is beneficial to sleep clinicians, respiratory physiologists, intensivists, trainees, and researchers. • Distills complex concepts into understandable language and figures, providing helping resource to the clinicians, that transforms a dry topic vis a viz control of ventilation into an exciting understandable ‘clinician’ language.

Author: Christophe Tribouilloy
Publisher: Frontiers Media SA
ISBN: 2832531644
Category : Medical
Languages : en
Pages : 153

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Mitral valve prolapse (MVP), consisting of an abnormal protrusion of mitral leaflets into the left atrium, is the main cause of severe mitral regurgitation and it often requires surgical or interventional correction. It mainly represents a typical adult disease with an average prevalence in industrialized countries ranging from 2 to 8%, but even the pediatric population may be affected showing specific features concerning both anatomy and treatment. Although its existence and clinical characteristics are known for several decades, every aspect of this pathological condition is in continuous evolution, being the subject of biologists’, cardiologists’ and surgeons’ active research. The aim of the present Research Topic is to address the MVP entity in its completeness, trying to describe all actual knowledge concerning molecular mechanisms, different clinical presentations (fibroelastic degeneration in elderly people or Barlow disease in young patients), diagnostic findings and tools (mainly represented by echocardiography and Nuclear Magnetic Resonance), their specific application to newly developed transcatheter and minimally invasive treatments, indications, surgical management and interventional strategies. For all these big chapters, special attention will be addressed to show temporal knowledge evolution and new elements acquisition, since the central message is that MVP is in flux and far from full comprehension.

Author: Anish Bhardwaj
Publisher: CRC Press
ISBN: 1420021044
Category : Medical
Languages : en
Pages : 549

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As the third leading cause of death in the United States, stroke accounts for one in every fifteen deaths and is the major cause of disability in the country. Compiled by a renowned editorial team, this reference bridges the gap between basic science and patient care protocols, and collects 43 expertly written chapters that range from laboratory-ba

Author: Morten Karsdal
Publisher: Academic Press
ISBN: 0128170697
Category : Science
Languages : en
Pages : 436

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There are 28 different collagens, with 46 unique chains, which allows for a collagen for each time and place. Some collagens are specialized for basement membrane, whereas others are the central structural component of the interstitial matrix. There are eight collagens among the 20 most abundant proteins in the body, which makes these molecules essential building blocks of tissues. In addition, lessons learned from monogenomic mutations in these proteins result in grave pathologies, exemplifying their importance in development. These molecules, and their post-translationally modified products serve as biomarkers of diseases in a range of pathologies associated with the extracellular matrix. Biochemistry of Collagens, Laminins, and Elastin: Structure, Function, and Biomarkers, Second Edition provides researchers and students current data on key structural proteins (collagens, laminins, and elastin), reviews on how these molecules affect pathologies, and information on how selected modifications of proteins can result in altered signaling properties of the original extracellular matrix component. Further, it discusses the novel concept that an increasing number of components of the extracellular matrix harbor cryptic signaling functions that may be viewed as endocrine function, and it highlights how this knowledge can be exploited to modulate fibrotic disease. - Provides an updated comprehensive introduction to collagen and structural proteins - Gives insight into emerging analytical technologies that can detect biomarkers of extracellular matrix degradation - Includes seven new chapters, including one on how collagen biomarkers are used in clinical research to support drug development and in precision medicine - Contains insights into the biochemical interactions and changes to structural composition of proteins in disease states - Proves the importance of proteins for collagen assembly, function, and durability

Author: Linda Elsegood
Publisher: Chelsea Green Publishing
ISBN: 1603589902
Category : Health & Fitness
Languages : en
Pages : 289

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A drug that is simultaneously affordable, devoid of severe side effects, and applicable to a wide range of diseases is one not often found in the modern pharmaceutical landscape. But as medical professionals and researchers alike have found, Low Dose Naltrexone (LDN) boasts this remarkable combination. LDN, originally prescribed in higher doses as a treatment for opioid addiction, works by blocking opioid receptors, thereby stimulating the production of endorphins, mitigating the inflammatory process, and stabilizing the immune response. Prescribed off-label and administered in small daily doses, this generic drug has proven useful in treating many different ailments. Expanding on the information presented in The LDN Book, Volume 1—which showcased LDN’s efficacy in treating conditions such as lupus, thyroiditis, autism spectrum disorder, and chronic fatigue—Volume 2 highlights the latest clinical trials, case studies, and research on LDN. More than a dozen medical professionals explain how they are using LDN to help patients suffering from chronic pain, Parkinson’s disease, dermatologic conditions, traumatic brain injury, Lyme disease, and more. The LDN Book, Volume 2 is both a resource for practitioners, pharmacists, and patients, and a renewed call for further research on a little-known drug with big potential.

Author: Kim Midwood
Publisher: Frontiers Media SA
ISBN: 2889744302
Category : Medical
Languages : en
Pages : 250

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Author: Bikram Kumar Gupta
Publisher: Jaypee Brothers Medical Publishers
ISBN: 935465889X
Category : Medical
Languages : en
Pages : 680

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Section 1 - General Critical Care Section 2 - Respiratory Critical Care Section 3 - Hepatic, Gastrointestinal & Endocrine Emergencies in ICU Section 4 - Neuro Critical Care Section 5 - Nephro Critical Care Section 6- Infections & Antibiotics Section 7- Obstetric Critical Care Section 8 - Trauma Critical Care Section 9 - Cardiac Critical Care Section 10- Poisoning Section 11- Onco Critical care

Author: Ming Xia
Publisher: Springer Nature
ISBN: 9819991676
Category :
Languages : en
Pages : 326

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