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Effects of Heat Stress and Fescue Toxicosis on the Immune System and Other Physiological Parameters

Effects of Heat Stress and Fescue Toxicosis on the Immune System and Other Physiological Parameters PDF Author: Deepan Kirubaharan Kishore
Publisher:
ISBN:
Category : Electronic dissertations
Languages : en
Pages : 188

Book Description
Tall fescue is widely used as pasture grass in the United States, and is the most important cool season grass for grazing animals. Certain fungi also grow on these grasses which produce toxins, resulting in reduced feed intake (FI), body weight (BW) and a compromised thermoregulatory system when consumed by animals . Our first study showed that sensitizing rats helped them adapt to the toxin by maintaining a lower core body temperature on subsequent exposure. The short-term study showed an increased proinflammatory response to stimulation with bacterial toxins. In the long-term study, the proinflammatory response was less severe with adaptation. However, cell mediated immunity was compromised, which makes animals susceptible to invading pathogens. This research identified adaptive responses to fescue toxicosis that highlighted shifts in immune function.

Effects of Heat Stress and Fescue Toxicosis on the Immune System and Other Physiological Parameters

Effects of Heat Stress and Fescue Toxicosis on the Immune System and Other Physiological Parameters PDF Author: Deepan Kirubaharan Kishore
Publisher:
ISBN:
Category : Electronic dissertations
Languages : en
Pages : 188

Book Description
Tall fescue is widely used as pasture grass in the United States, and is the most important cool season grass for grazing animals. Certain fungi also grow on these grasses which produce toxins, resulting in reduced feed intake (FI), body weight (BW) and a compromised thermoregulatory system when consumed by animals . Our first study showed that sensitizing rats helped them adapt to the toxin by maintaining a lower core body temperature on subsequent exposure. The short-term study showed an increased proinflammatory response to stimulation with bacterial toxins. In the long-term study, the proinflammatory response was less severe with adaptation. However, cell mediated immunity was compromised, which makes animals susceptible to invading pathogens. This research identified adaptive responses to fescue toxicosis that highlighted shifts in immune function.

Temporal Effects of Fescue Toxicosis and Heat Stress on Rat Physiology and Hepatic Gene Expression

Temporal Effects of Fescue Toxicosis and Heat Stress on Rat Physiology and Hepatic Gene Expression PDF Author: Raja Sekhar Settivari
Publisher:
ISBN:
Category : Electronic dissertations
Languages : en
Pages :

Book Description
Fescue toxicosis results from intake of toxins in fescue containing an endophytic fungus, Neotyphodium coenophialum. Time-related changes in rats associated with intake of an endophyte-infected fescue diet (E+) were evaluated under thermoneutral (TN), and both short- and long-term heat stress (HS) conditions. Short-term E+ intake decreased feed intake and growth rate under both conditions, whereas rats exhibited signs of adaptation during long-term exposure with better recovery occurring under TN conditions. Rats fed an E+ diet did not change core temperature during TN, but under HS conditions they exhibited a short-term increase in core temperature above control level. However, there was adaptive return of this temperature to TN level with long-term exposure. Short-term E+ intake at TN decreased serum glucose, urea nitrogen, alkaline phosphatase, and cholesterol; whereas long-term E+ intake under these conditions resulted in complete adaptation. In contrast, short-term E+ intake at HS did not affect serum biochemistry, while long-term intake decreased all the above mentioned serum parameters. Serum prolactin level was decreased during both short- or long-term TN and HS conditions. The E+ diet decreased hepatic antioxidant gene expression, with even greater reduction as a result of HS. Long-term E+ intake and HS increased expression of cytochrome P450 and detoxification pathways, respectively. Genes associated with immune response increased with long-term E+ at TN, but decreased with E+ diet at HS. Similarly, genes coding for chaperone and DNA repair decreased with long-term E+ at TN, but increased with E+ and HS. Recovery observed in E+ rats at TN could be attributed to increased gene expression for detoxification and immune response, whereas decreased antioxidant and immune response associated genes could contribute to distress associated with E+ at HS. Fescue toxicosis results from intake of toxins in fescue containing an endophytic fungus, Neotyphodium coenophialum. Time-related changes in rats associated with intake of an endophyte-infected fescue diet (E+) were evaluated under thermoneutral (TN), and both short- and long-term heat stress (HS) conditions. Short-term E+ intake decreased feed intake and growth rate under both conditions, whereas rats exhibited signs of adaptation during long-term exposure with better recovery occurring under TN conditions. Rats fed an E+ diet did not change core temperature during TN, but under HS conditions they exhibited a short-term increase in core temperature above control level. However, there was adaptive return of this temperature to TN level with long-term exposure. Short-term E+ intake at TN decreased serum glucose, urea nitrogen, alkaline phosphatase, and cholesterol; whereas long-term E+ intake under these conditions resulted in complete adaptation. In contrast, short-term E+ intake at HS did not affect serum biochemistry, while long-term intake decreased all the above mentioned serum parameters. Serum prolactin level was decreased during both short- or long-term TN and HS conditions. The E+ diet decreased hepatic antioxidant gene expression, with even greater reduction as a result of HS. Long-term E+ intake and HS increased expression of cytochrome P450 and detoxification pathways, respectively. Genes associated with immune response increased with long-term E+ at TN, but decreased with E+ diet at HS. Similarly, genes coding for chaperone and DNA repair decreased with long-term E+ at TN, but increased with E+ and HS. Recovery observed in E+ rats at TN could be attributed to increased gene expression for detoxification and immune response, whereas decreased antioxidant and immune response associated genes could contribute to distress associated with E+ at HS.

Environmental Stress and Amelioration in Livestock Production

Environmental Stress and Amelioration in Livestock Production PDF Author: Veerasamy Sejian
Publisher: Springer Science & Business Media
ISBN: 3642292054
Category : Science
Languages : en
Pages : 577

Book Description
Given the importance of livestock to the global economy, there is a substantial need for world-class reference material on the sustainable management of livestock in diverse eco-regions. With uncertain climates involving unpredictable extreme events (e.g., heat, drought, infectious disease), environmental stresses are becoming the most crucial factors affecting livestock productivity. By systematically and comprehensively addressing all aspects of environmental stresses and livestock productivity, this volume is a useful tool for understanding the various intricacies of stress physiology. With information and case studies collected and analyzed by professionals working in diversified ecological zones, this book explores the influence of the environment on livestock production across global biomes. The challenges the livestock industry faces in maintaining the delicate balance between animal welfare and production are also highlighted.

Tall Fescue for the Twenty-first Century

Tall Fescue for the Twenty-first Century PDF Author: Henry A. Fribourg
Publisher: ASA-CSSA-SSSA
ISBN: 9780891181729
Category : Nature
Languages : en
Pages : 574

Book Description
"Book and Multimedia Publishing Committee; David Baltensperger, chair ... [et al.]."

Heat Stress and Animal Productivity

Heat Stress and Animal Productivity PDF Author: Anjali Aggarwal
Publisher: Springer Science & Business Media
ISBN: 813220879X
Category : Science
Languages : en
Pages : 200

Book Description
Dr. Anjali Aggarwal is working as a Senior Scientist at National Dairy Research Institute, Karnal (India). She holds a PhD degree in Animal Physiology and is involved in research and teaching at post-graduate level. Her area of research work is stress and environmental physiology. She has more than 50 publications, two technical bulletins, four manuals and many book chapters to her credit. She has successfully guided many post-graduate and PhD students. Her major research accomplishments are on microclimatic modification for alleviation of heat and cold stress, mist and fan cooling systems for cows and buffaloes, and use of wallowing tank in buffaloes. Her work involves the use of technology of supplementing micronutrients during dry period and early lactation to crossbred and indigenous cows for alleviating metabolic and oxidative stress and improved health and productivity. Studies are also done in her lab on partitioning of heat loss from skin and pulmonary system of cattle and buffaloes as a result of exercise or exposure to heat stress. Dr. R.C. Upadhyay is working as Head, Dairy Cattle Physiology Division at National Dairy Research Institute, Karnal (India). He graduated in Veterinary Sciences and obtained his PhD degree in Animal Physiology. His area of recent research is climate change, stress, and environmental physiology. His major research accomplishment is on climate change impact assessment of milk production and growth in livestock. His work also involves studying methane conversion and emission factors for Indian livestock and use of IPCC methodology of methane inventory of Indian livestock. Heat shock protein-70 expression studies in cattle and buffaloes are also done in his lab. Draught animal power evaluation, fatigue assessment, work-rest cycle and work limiting factors form the highlights of his work. Studies on partitioning of heat loss from skin and pulmonary system of cattle and buffaloes and electrocardiographic studies in cattle, buffalo, sheep and goat are also undertaken in his lab. He has more than 75 research papers, four books and several book chapters to his credit. Technologies developed and research done by him include methodology of methane measurement: open and closed circuit for cattle and buffaloes; inventory of methane emission from livestock using IPCC methodology; livestock stress index: thermal stress measurement based on physiological functions; and draught power evaluation system and large animal treadmill system. He received training in Radio-nuclides in medicine at Australian School of Nuclear Technology, Lucas heights, NSW, Australia in 1985 and Use of radioisotopes in cardiovascular investigations at CSIRO, Prospect, NSW, Australia, during 1985-86. He has guided several post-graduate and PhD students. He is recipient of Hari Om Ashram Award-1990 (ICAR) for outstanding research in animal sciences.

Harm and Benefit of Plant and Fungal Secondary Metabolites in Food Animal Production

Harm and Benefit of Plant and Fungal Secondary Metabolites in Food Animal Production PDF Author: Michael D. Flythe
Publisher: Frontiers Media SA
ISBN: 2889455068
Category :
Languages : en
Pages : 100

Book Description
Livestock species are either herbivores or omnivores that are maintained largely on plant-based diets. We have long appreciated the importance of understanding dietary plants from both nutritional and agronomic perspectives. However, it is increasingly clear that the fungi, bacteria and other microorganisms that live in the plants and animals are also significant factors in the ecology of agricultural animals. Many of the effects exerted on animals by dietary plants are attributable to secondary metabolites produced by the plants themselves or commensal microorganisms. Some fungal and plant secondary metabolites have multiple biological effects. We must be careful not to categorize a plant as strictly beneficial or harmful. Furthermore, we must be careful not to categorize even a particular plant or fungal compound as strictly beneficial or harmful. Rather, the harm or benefit of secondary metabolites are often dependent on the metabolic status of the animal, the interaction with other dietary factors including other secondary metabolites, and the dose received through the diet. This collection examines a range of agriculturally important plant and fungal products including essential oils, alkaloids, isoflavones and nitrates.

Nitric Oxide in Developing Plant Stress Resilience

Nitric Oxide in Developing Plant Stress Resilience PDF Author: M. Iqbal R Khan
Publisher: Academic Press
ISBN: 0323916260
Category : Science
Languages : en
Pages : 348

Book Description
Nitric Oxide in Developing Plant Stress Resilience presents a strong focus on genetics and molecular mechanisms, examining crosstalk with other signaling molecules and the role this plays in the alleviation of oxidative damage. Abiotic stress negatively impacts plants productivity and alters the metabolism at the cellular or whole plant level, disturbing the mineral nutrients status, enzyme activities and osmotic homeostasis. Beginning with the biosynthesis of NO and its mode of action, chapters review various molecular interactions, including phytohormonal crosstalk, ROS metabolism, post-translational modification, and nutrients homeostasis. In addition, the book also highlights genome editing and proteomic approaches that can be used to manipulate NO responses. This is an essential resource for students and researchers interested in plant physiology, biochemistry and genetics. - Highlights how Nitric Oxide acts as a signaling molecule and the ways in which this can help plants develop stress tolerance - Discusses how NO interacts with other signaling molecules, including crosstalk - Considers the advances and future implications of NO in agriculture

Abstracts - American Society of Animal Science

Abstracts - American Society of Animal Science PDF Author:
Publisher:
ISBN:
Category : Animal culture
Languages : en
Pages : 562

Book Description
Consists of abstracts of papers presented at the national and sectional meetings of the American Society of Animal Science.

Journal of Animal Science

Journal of Animal Science PDF Author:
Publisher:
ISBN:
Category : Livestock
Languages : en
Pages : 558

Book Description


Index Medicus

Index Medicus PDF Author:
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1508

Book Description
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.