Author: Orlena Hsin Cheng
Publisher:
ISBN:
Category :
Languages : en
Pages : 218
Book Description
Effects of Estradiol Administration on Nitrogen Metabolism and Insulin-like Growth Factor-I Gene Expression in Growing Ruminants
Regulation of the Growth Hormone Receptor, Insulin-like Growth Factor (IGF) I and IGF Binding Protein 2 in Reproductive Tissues of Dairy Cattle During Lactation and Associated Effects on Fertility
Author: Michelle Lynn Bode-Rhoads
Publisher:
ISBN:
Category : Somatomedin
Languages : en
Pages : 376
Book Description
The components of the growth hormone (GH)/insulin-like growth factor (IGF) system play critical reproductive and metabolic roles in dairy cattle. In liver, GH receptor (GHR) and IGF-I are dynamically regulated by lactation and energy balance. Less is known about the regulation of GHR and IGF-I mRNA in reproductive tissues. The objective of these studies was to measure the expression of total GHR (tGHR), IGF-I and IGF binding protein (IGFBP) 2 mRNA in reproductive tissues during several stages of lactation and around the time of artificial insemination. Changes in gene expression were then evaluated for potential effects on fertility. The expression of tGHR, IGF-I and IGFBP-2 was measured in uterine, luteal, follicular and hepatic tissue three times during the early postpartum period. Expression of tGHR and IGFBP-2 mRNA in the reproductive tissues did not change during early lactation. Luteal and follicular expression of IGF-I changed in an inverse manner from the second sample collection to the third (luteal expression decreased and follicular expression increased). Further research is needed to elucidate the implications these changes have for fertility in dairy cattle. The expression of tGHR, IGF-I and IGFBP-2 was also measured in uterine and hepatic tissue at several stages of lactation around the time of insemination. Uterine tGHR mRNA, uterine IGF-I mRNA and plasma IGF-I concentrations increased at estrus. The timing of these changes suggests that uterine IGF-I does not directly affect early embryonic development, but may enhance the uterine environment for early embryonic development. The cows that became pregnant had higher liver tGHR and IGFBP-2 mRNA concentrations. The cows that became pregnant may have been metabolically distinct from the cows that did not become pregnant, resulting in different levels of hepatic gene expression and providing a reproductive advantage.
Publisher:
ISBN:
Category : Somatomedin
Languages : en
Pages : 376
Book Description
The components of the growth hormone (GH)/insulin-like growth factor (IGF) system play critical reproductive and metabolic roles in dairy cattle. In liver, GH receptor (GHR) and IGF-I are dynamically regulated by lactation and energy balance. Less is known about the regulation of GHR and IGF-I mRNA in reproductive tissues. The objective of these studies was to measure the expression of total GHR (tGHR), IGF-I and IGF binding protein (IGFBP) 2 mRNA in reproductive tissues during several stages of lactation and around the time of artificial insemination. Changes in gene expression were then evaluated for potential effects on fertility. The expression of tGHR, IGF-I and IGFBP-2 was measured in uterine, luteal, follicular and hepatic tissue three times during the early postpartum period. Expression of tGHR and IGFBP-2 mRNA in the reproductive tissues did not change during early lactation. Luteal and follicular expression of IGF-I changed in an inverse manner from the second sample collection to the third (luteal expression decreased and follicular expression increased). Further research is needed to elucidate the implications these changes have for fertility in dairy cattle. The expression of tGHR, IGF-I and IGFBP-2 was also measured in uterine and hepatic tissue at several stages of lactation around the time of insemination. Uterine tGHR mRNA, uterine IGF-I mRNA and plasma IGF-I concentrations increased at estrus. The timing of these changes suggests that uterine IGF-I does not directly affect early embryonic development, but may enhance the uterine environment for early embryonic development. The cows that became pregnant had higher liver tGHR and IGFBP-2 mRNA concentrations. The cows that became pregnant may have been metabolically distinct from the cows that did not become pregnant, resulting in different levels of hepatic gene expression and providing a reproductive advantage.
Effect of Exogenous Administration of Bovine Somatotropin on Protein Turnover and Nutrient Utilization in the Hindlimb of Growing Cattle
Author: Yves Rejean Boisclair
Publisher: Ann Arbor, Mich. : University Microfilms International
ISBN:
Category :
Languages : en
Pages : 496
Book Description
Publisher: Ann Arbor, Mich. : University Microfilms International
ISBN:
Category :
Languages : en
Pages : 496
Book Description
The Insulin-like Growth Factor-I Gene Expression Response to Source of Supplemental Protein and Dose-dependent Effect of Exogenous Bovine Somatotropin Administration in Ovine Liver
Dissertation Abstracts International
Author:
Publisher:
ISBN:
Category : Dissertations, Academic
Languages : en
Pages : 1044
Book Description
Publisher:
ISBN:
Category : Dissertations, Academic
Languages : en
Pages : 1044
Book Description
Effect of Undegradable Intake Protein and Estradiol-17 Beta on Nitrogen Metabolism and Circulating Hormones in Growing Holstein Steers
Author: Kathleen Debra Finnerty
Publisher:
ISBN:
Category :
Languages : en
Pages : 150
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 150
Book Description
Cumulated Index Medicus
Metabolic Modifiers
Author: National Research Council
Publisher: National Academies
ISBN: 0309049970
Category : Technology & Engineering
Languages : en
Pages : 94
Book Description
In the past decade, animal scientists have learned that administering recombinantly derived somatotropin (growth hormone) to cows improves milk production and that giving beta-adrenergic agonists to meat animals improves productivity and leanness. In order for these metabolic modifiers to yield benefits, however, sound management of the animals' nutrition is necessary. This volume reports on how these substances work in the animals' metabolism, what effects they might have on nutrient requirements of domestic livestock, and what information should be developed further by investigators. The book explores the current understanding of the biology, structure, mechanisms of action, and treatment effects of somatotropin, beta-adrenergic agonists, and anabolic steroids. A companion volume to the Nutrient Requirements of Domestic Animals series, this authoritative volume will be required reading for animal scientists, researchers, veterinarians, livestock farmers, and faculty and students in university animal veterinary science programs.
Publisher: National Academies
ISBN: 0309049970
Category : Technology & Engineering
Languages : en
Pages : 94
Book Description
In the past decade, animal scientists have learned that administering recombinantly derived somatotropin (growth hormone) to cows improves milk production and that giving beta-adrenergic agonists to meat animals improves productivity and leanness. In order for these metabolic modifiers to yield benefits, however, sound management of the animals' nutrition is necessary. This volume reports on how these substances work in the animals' metabolism, what effects they might have on nutrient requirements of domestic livestock, and what information should be developed further by investigators. The book explores the current understanding of the biology, structure, mechanisms of action, and treatment effects of somatotropin, beta-adrenergic agonists, and anabolic steroids. A companion volume to the Nutrient Requirements of Domestic Animals series, this authoritative volume will be required reading for animal scientists, researchers, veterinarians, livestock farmers, and faculty and students in university animal veterinary science programs.
American Doctoral Dissertations
Author:
Publisher:
ISBN:
Category : Dissertation abstracts
Languages : en
Pages : 816
Book Description
Publisher:
ISBN:
Category : Dissertation abstracts
Languages : en
Pages : 816
Book Description
Index Medicus
Author:
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1956
Book Description
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1956
Book Description
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.