Effects of Device Type and Liquid Composition on Characteristics of Aerosols Generated from Tank-style E-cigarette and JUUL Pod PDF Download

Author: Yuening Guo
Publisher:
ISBN:
Category :
Languages : en
Pages : 33

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Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 030946837X
Category : Medical
Languages : en
Pages : 775

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Book Description
Millions of Americans use e-cigarettes. Despite their popularity, little is known about their health effects. Some suggest that e-cigarettes likely confer lower risk compared to combustible tobacco cigarettes, because they do not expose users to toxicants produced through combustion. Proponents of e-cigarette use also tout the potential benefits of e-cigarettes as devices that could help combustible tobacco cigarette smokers to quit and thereby reduce tobacco-related health risks. Others are concerned about the exposure to potentially toxic substances contained in e-cigarette emissions, especially in individuals who have never used tobacco products such as youth and young adults. Given their relatively recent introduction, there has been little time for a scientific body of evidence to develop on the health effects of e-cigarettes. Public Health Consequences of E-Cigarettes reviews and critically assesses the state of the emerging evidence about e-cigarettes and health. This report makes recommendations for the improvement of this research and highlights gaps that are a priority for future research.

Author: Yinping Zhang
Publisher: Springer Nature
ISBN: 9811676801
Category : Science
Languages : en
Pages : 2182

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Book Description
People live in indoor environment about 90% of lifetime and an adult inhales about 15 kg air each day, over 75% of the human body’s daily mass intake (air, food, water). Therefore, indoor air quality (IAQ) is very important to human health. This book provides the basic knowledge of IAQ and highlights the research achievements in the past two decades. It covers the following 12 sections: introduction, indoor air chemicals, indoor air particles, measurement and evaluation, source/sink characteristics, indoor chemistry, human exposure to indoor pollutants, health effects and health risk assessment, IAQ and cognitive performance, standards and guidelines, IAQ control, and air quality in various indoor environments. It provides a combination of an introduction to various aspects on IAQ studies, the current state-of-knowledge, various advances and the perspective of IAQ studies. It will be very helpful for the researchers and technicians in the IAQ and the related fields. It is also useful for experts in other fields and general readers who want to obtain a basic understanding of and research advances in the field of IAQ. A group of experts in IAQ research have been recruited to write the chapters. Their research interests and experience cover the scope of the book. In addition, some experienced experts in IAQ field have been invited as advisors or reviewers to give their comments, suggestions and revisions on the handbook framework and the chapter details. Their contribution guarantees the quality of the book. We are very grateful to them. Last but not least, we express our heartfelt thanks to Prof. Spengler, Harvard University, for writing the foreword of the current Handbook of Indoor Air Quality both as a pioneer scientist who contributed greatly to indoor air science and as an Editor-in-chief of Handbook of Indoor Air Quality 2001, 1st ed. New York: McGraw-Hill. In addition to hard copies, the book is also published online and will be updated by the authors as needed to keep it aligned with current knowledge. These salient features can make the handbook fresh with the research development.

Author: United States. Public Health Service. Office of the Surgeon General
Publisher:
ISBN:
Category : Government publications
Languages : en
Pages : 728

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This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.

Author: Chamodhi Ravihansi Polgampola Ralalage
Publisher:
ISBN:
Category : Aerosols
Languages : en
Pages : 0

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"Electronic cigarettes (e-cigarettes) generate aerosol (particles in a gas matrix) by vaporizing the e-liquid, consisting of propylene glycol (PG), glycerol (GL), nicotine, and other additives. Aerosol enters the respiratory tract (RT) of the user, where part of it is deposited, while the rest is exhaled. Compounds in the gas and particle phase have different deposition mechanisms in the RT, thus determining the location of deposition. The location of deposition and amount of a compound will influence the biological response in the body. Identifying the composition of each constituent in the gas phase and particle phase would enhance the understanding of their deposition in the RT, thus absorption into the body. Study 1: assess the composition difference in aerosol particle phase (PP) from its e-liquid, and identify the mechanism associated with the composition difference. Gas chromatography analysis was conducted on e-liquid and aerosol PP for PG, GL, and nicotine. Experiments were designed to isolate the mechanism for composition difference by testing evaporation, aging, vaporization, and condensation. Study 2: streamline a methodology to study impact of user-specific parameters on aerosol deposition in e-cigarette users. A pilot study was conducted with participation of e-cigarette consumers to test the usability of exhale breath collection device. Feasibility of quantifying yield, exhale breath, puff and respiratory topographies were evaluated. Salivary cotinine boost was quantified to measure nicotine uptake. PG in aerosol PP showed a significant reduction from the e-liquid. Nicotine composition difference between e-liquid and the PP for non-acidified e-liquid was greater from acidified e-liquids. Study data is in agreement with the condensation model to explain the composition change of aerosol PP vs the initial e-liquid. The pilot study successfully quantified exhale breath composition, deposition efficiencies, salivary cotinine boost, puff and respiratory topographies. Findings confirmed the composition of aerosol PP to be different from its e-liquid and identified the mechanism for the difference. Pilot study successfully demonstrated the proof of concept to study the impact of user-specific parameters in e-cigarette users."--Abstract.

Author: Brian Flannigan
Publisher: CRC Press
ISBN: 0203302931
Category : Science
Languages : en
Pages : 555

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Despite the large amount of money spent on research into pollution of the indoor environment, the problem remains complex with major gaps in our knowledge of the identities and sources of pollutants and of the effects of prolonged exposure to indoor pollutants on health. Microorganisms in Home and Indoor Work Environments considers one such group o

Author: Ramesh C Gupta
Publisher: Academic Press
ISBN: 0323915604
Category : Medical
Languages : en
Pages : 1558

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Book Description
**Selected for Doody's Core Titles® 2024 in Toxicology** Reproductive and Developmental Toxicology, Third Edition is a comprehensive and authoritative resource, providing the latest literature on this complex subject by focusing on three core components - parent, placenta and fetus - and the continuous changes that occur in each. Enriched with relevant references describing every aspect of reproductive toxicology, this revised and updated resource addresses the totality of the subject, discussing a broad range of topics including nanoparticles and radiation, gases and solvents, smoking, alcohol and drugs of abuse, and metals, among others. In addition, it is the only resource to include reproductive and developmental toxicity in domestic animals, fish and wildlife With a special focus on placental toxicity, this book is the only available reference to connect the three key risk stages. Completely revised and updated to include the most recent developments in the field, this book is an essential resource for advanced students and researchers in toxicology, as well as biologists, pharmacologists and teratologists from academia, industry and regulatory agencies. - Provides a complete, up-to-date, integrated source of information on the key risk stages during reproduction and development - Offers diverse and unique in vitro and in vivo toxicity models for reproductive and developmental toxicity testing in a user-friendly format that assists in comparative analysis - Includes new chapters on developments in systems toxicology and predictive modeling of male developmental toxicity, adverse outcome pathways in reproductive and developmental toxicology, ovarian and endometrial toxicity, developmental neurotoxicity of air pollution, and more

Author: Roger O McClellan
Publisher: CRC Press
ISBN: 9780367401580
Category :
Languages : en
Pages : 648

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Recent developments have provided new data on the subject of inhalation toxicology, requiring an update of the previous edition of this popular text. Like the first, this second edition explains the basic concepts and quantitative approaches in inhalation toxicology, and it gives a comprehensive treatment of evaluations of respiratory responses to inhaled particles and gases. The author here explores new understanding of the role of cytokines in pulmonary inflammation and risk assessment. Immunologists, oncologists, respiratory specialists and students in those fields will find Concepts In Inhalation Toxicology to be essential to their practice.

Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309316278
Category : Medical
Languages : en
Pages : 341

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Tobacco use by adolescents and young adults poses serious concerns. Nearly all adults who have ever smoked daily first tried a cigarette before 26 years of age. Current cigarette use among adults is highest among persons aged 21 to 25 years. The parts of the brain most responsible for cognitive and psychosocial maturity continue to develop and change through young adulthood, and adolescent brains are uniquely vulnerable to the effects of nicotine. At the request of the U.S. Food and Drug Administration, Public Health Implications of Raising the Minimum Age of Legal Access to Tobacco Products considers the likely public health impact of raising the minimum age for purchasing tobacco products. The report reviews the existing literature on tobacco use patterns, developmental biology and psychology, health effects of tobacco use, and the current landscape regarding youth access laws, including minimum age laws and their enforcement. Based on this literature, the report makes conclusions about the likely effect of raising the minimum age to 19, 21, and 25 years on tobacco use initiation. The report also quantifies the accompanying public health outcomes based on findings from two tobacco use simulation models. According to the report, raising the minimum age of legal access to tobacco products, particularly to ages 21 and 25, will lead to substantial reductions in tobacco use, improve the health of Americans across the lifespan, and save lives. Public Health Implications of Raising the Minimum Age of Legal Access to Tobacco Products will be a valuable reference for federal policy makers and state and local health departments and legislators.

Author:
Publisher:
ISBN:
Category : Glycols
Languages : en
Pages : 126

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