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Author: Subash Chandra Gupta Publisher: Springer ISBN: 3319413422 Category : Medical Languages : en Pages : 410
Book Description
Second comprehensive volume focuses on anti-inflammatory nutraceuticals and their role in prevention and therapy of various chronic diseases. Food and drug administration (FDA) approved drugs such as steroids, non-steroidal anti-inflammatory drugs (NSAIDS), statins and metformin have been shown to modulate inflammatory pathways, but their long-term intake has been associated with numerous side effects. Thus dietary agents which can modulate inflammatory pathways in humans, are likely to exhibit enormous potential. Leading experts describe the latest results of anti-inflammatory nutraceuticals and their role in prevention and therapy of various chronic diseases.
Author: Subash Chandra Gupta Publisher: Springer ISBN: 3319413422 Category : Medical Languages : en Pages : 410
Book Description
Second comprehensive volume focuses on anti-inflammatory nutraceuticals and their role in prevention and therapy of various chronic diseases. Food and drug administration (FDA) approved drugs such as steroids, non-steroidal anti-inflammatory drugs (NSAIDS), statins and metformin have been shown to modulate inflammatory pathways, but their long-term intake has been associated with numerous side effects. Thus dietary agents which can modulate inflammatory pathways in humans, are likely to exhibit enormous potential. Leading experts describe the latest results of anti-inflammatory nutraceuticals and their role in prevention and therapy of various chronic diseases.
Author: Frank Petersen Publisher: Springer Science & Business Media ISBN: 3764381175 Category : Medical Languages : en Pages : 380
Book Description
In a real tour de force of pharmacological literature, this edited volume’s chapters highlight the biodiversity-driven approaches which are now of eminent importance in natural products research. It addresses the question why natural products display such complex chemical information, what makes them unique, as they often are, and what their characteristics are. Practical questions such as supply of natural substances and production optimization strategies are also covered.
Author: S. Grabley Publisher: Springer ISBN: 9783642602504 Category : Medical Languages : en Pages : 0
Book Description
This book is unique in covering the present status and future potential of natural products in drug discovery. It provides readers with recent information regarding the impact on drug discovery, development and strategies, technical and automation aspects, and methods based on biochemistry as well as molecular biology, highlighting compounds from natural sources. Special emphasis is placed on the various strategies to gain access to natural compounds and combinatorial approaches by making use of both synthetic and biological methods.
Author: Goutam Brahmachari Publisher: World Scientific ISBN: 9814335371 Category : Science Languages : en Pages : 695
Book Description
Bioactive natural products are a rich source of novel therapeutics. Thus, the search for bioactive molecules from nature continues to play an important role in fashioning new medicinal agents. This volume, which comprises sixteen chapters written by active researchers and leading experts in natural products chemistry, brings together an overview of current discoveries in this remarkable field. It also provides information on the industrial application of natural products for medicinal purposes. This book will serve as a valuable resource for researchers to predict promising leads for developing pharmaceuticals to treat various ailments and disease manifestations.
Author: Ramarao Poduri Publisher: Springer Nature ISBN: 9811555346 Category : Medical Languages : en Pages : 522
Book Description
This book describes the processes that are involved in the development of new drugs. The authors discuss the history, role of natural products and concept of receptor interactions with regard to the initial stages of drug discovery. In a single, highly readable volume, it outlines the basics of pharmacological screening, drug target identification, and genetics involved in early drug discovery. The final chapters introduce readers to stem therapeutics, pharmacokinetics, pharmacovigilance, and toxicological testing. Given its scope, the book will enable research scholars, professionals and young scientists to understand the key fundamentals of drug discovery, including stereochemistry, pharmacokinetics, clinical trials, statistics and toxicology.
Author: Andrew G. Mtewa Publisher: John Wiley & Sons ISBN: 1119650232 Category : Science Languages : en Pages : 444
Book Description
Focusing on phytochemicals and their potential for drug discovery, this book offers a comprehensive resource on poisonous plants and their applications in chemistry and in pharmacology. Provides a comprehensive resource on phytotoxins, covering historical perspectives, modern applications, and their potential in drug discovery Covers the mechanisms, benefits, risks and management protocols of phytotoxins in a scientific laboratory and the usefulness in drug discovery Presents chapters in a carefully designed, clear order, making it an ideal resource for the academic researcher or the industry professional at any stage in their career
Author: Jan Vilcek Publisher: Seven Stories Press ISBN: 1609806697 Category : Science Languages : en Pages : 272
Book Description
Long before he became one of the world's most celebrated immunologists, Jan Vilcek began life in Slovakia as the child of Jewish parents at a time when Jews were being exterminated all across Europe. He owes his and his mother’s survival to the courage of brave people and good luck. As a young man growing up in Czechoslovakia in the aftermath of the Second World War, Vilcek went to medical school and chose a career in virology and immunology at a time when these fields were still in their infancy. While still in his twenties he published a paper in the prestigious journal Nature, and he hosted the first international conference on interferon. Fleeing Communist Czechoslovakia with his wife Marica, Vilcek continued his research at NYU School of Medicine, going on to establish a highly successful career in biomedical research, and creating one of the most important and trailblazing medicines of our age. After his arrival in the US in 1965 as a penniless refugee, he soon went on to spearhead some of the key advances in the research of interferon that enabled its therapeutic application, and through his research into tumor necrosis factor (TNF) made advances that led to the discovery of new genes and proteins and signaling pathways, opening up previously uncharted areas of medical innovation that have led to important new treatments for a wide range of autoimmune and inflammatory diseases. Along the way Vilcek acquired material wealth he had never aspired to, catapulting him into the world of philanthropy. Love and Science shows how advances in science sometimes result from the greatest disappointments, and how achievement in medical research is usually a team effort, where ideas are shared, where friendship and love sometimes matter most and serendipity is as important as a will to succeed—and where, over time, the least expected thing sometimes becomes the most important. In Vilcek's case the vaunted cure for cancer that many saw in TNF never materialized. However, out of the ashes of that hope came many related treatments that have changed countless lives and alleviated much suffering.
Author: Victor E. Marquez Publisher: CRC Press ISBN: 1000462943 Category : Medical Languages : en Pages : 566
Book Description
The Ups and Downs in Drug Design: Adventures in Medicinal Chemistry highlights the necessity for an integrative approach in medicinal chemistry and chemical biology. As medicinal chemistry is not a monolithic science, it is important to emphasize the other various disciplines that are required for successful drug design. This book presents the author’s own personal experience in this field and describes the "ups" and "downs" that come with drug discovery. It is an excellent companion text for graduate and postgraduate students who would like further insight into the parameters of drug design, including the challenges that come with the project. Key Features Illustrates "real-life" examples in medicinal chemistry Integrates the use of physical, chemical, and biological concepts that are important in drug design Highlights the "ups" and "downs" that come with drug discovery Aims to inspire students who may be struggling with the challenges and thought process in drug design Intends to be an excellent companion text for graduate and postgraduate students
Author: Publisher: Academic Press ISBN: 012820186X Category : Medical Languages : en Pages : 364
Book Description
Pharmacological Advances in Natural Product Drug Discovery, Volume 87 in the Advances in Pharmacology series, presents the latest pharmacological research progresses of 8 medicinal compounds from natural products, including salvianolic acid, tanshinone, paeonol, chlorogenic acid, astragaloside, icariin, ganoderan, and febrifugine. Specific chapters to this new release include Potential Role of Paeonol on Atherosclerosis Related Cells, A Review on Salvianolic Acid, Pharmacological Advances of Tanshinones, the Natural Product of Salvia Miltiorrhiza, Pharmacological Action and Potential Targets Analysis of Major Pharmacological Effects of Chlorogenic Acid, Modern TCM: Identifying and Defining the "Medicinal Mix", Pharmacological Advances in Astragaloside IV Derived from Astragalus Membranaceus, and much more. Includes the authority and expertise of leading contributors in natural product pharmacology Provides the latest pharmacological research progresses of eight medicinal compounds from natural products Presents a thorough discussion on the compatibility of traditional medicines
Author: Sean B. Carroll Publisher: Princeton University Press ISBN: 140088554X Category : Science Languages : en Pages : 285
Book Description
Now the subject of an Emmy Award–winning film the New York Times calls "spellbinding" How does life work? How does nature produce the right numbers of zebras and lions on the African savanna, or fish in the ocean? How do our bodies produce the right numbers of cells in our organs and bloodstream? In The Serengeti Rules, award-winning biologist and author Sean Carroll tells the stories of the pioneering scientists who sought the answers to such simple yet profoundly important questions, and shows how their discoveries matter for our health and the health of the planet we depend upon. One of the most important revelations about the natural world is that everything is regulated—there are rules that regulate the amount of every molecule in our bodies and rules that govern the numbers of every animal and plant in the wild. And the most surprising revelation about the rules that regulate life at such different scales is that they are remarkably similar—there is a common underlying logic of life. Carroll recounts how our deep knowledge of the rules and logic of the human body has spurred the advent of revolutionary life-saving medicines, and makes the compelling case that it is now time to use the Serengeti Rules to heal our ailing planet. A bold and inspiring synthesis by one of our most accomplished biologists and gifted storytellers, The Serengeti Rules is the first book to illuminate how life works at vastly different scales. Read it and you will never look at the world the same way again.
Author: Subash Chandra Gupta
Author: Subash Chandra Gupta
Author: Frank Petersen
Author: S. Grabley
Author: Goutam Brahmachari
Author: Ramarao Poduri
Author: Andrew G. Mtewa
Author: Jan Vilcek
Author: Victor E. Marquez
Author: 
Author: Sean B. Carroll