Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Memory Reconsolidation PDF full book. Access full book title Memory Reconsolidation by Michelle H. Lonergan. Download full books in PDF and EPUB format.
Author: Michelle H. Lonergan Publisher: Elsevier Inc. Chapters ISBN: 0128057971 Category : Psychology Languages : en Pages : 32
Book Description
Background: Considering the pivotal role of negative emotional experiences in the development and persistence of mental disorders, effectively interfering with the consolidation/reconsolidation of such experiences would open the door to a novel treatment approach in psychiatry. Objective: We assessed the current evidence regarding the capacity of the β-blocker propranolol to block the consolidation/reconsolidation of emotional memories by means of a meta-analytic review. Data sources: An extensive multilingual literature search from 1994 to 2011 yielded 189 potential articles. Study selection: Selected studies consisted of randomized, double-blind experiments assessing long-term memory for emotional material in adults and involving at least one propranolol and one placebo condition. Of 189 potential studies, 13 consolidation ( n = 310) and 9 reconsolidation ( n = 327) experiments with adults met inclusion criteria for statistical analysis. Data extraction: Two independent reviewers extracted outcome and descriptive data from each study. Effect sizes were calculated using a random effects model. Data synthesis: Compared to placebo, propranolol given before memory consolidation reduced subsequent recall for negatively valenced stories, pictures, word lists, and the expression of cue-elicited fear responses: Hedge’s g = 0.47, 95% CI = 0.22–0.72. Moreover, compared to placebo, propranolol before memory reconsolidation reduced subsequent recall for negatively valenced emotional words, as well as the expression of cue-elicited fear responses, g = 0.59, 95% CI = 0.16–1.01. Splitting the results according to episodic retention and physiological responding did not yield a significant difference in effect size for consolidation or reconsolidation blockade. Removing the clinical studies from the larger group of nonclinical studies did not impact the statistical significance of the results either. Conclusions: Propranolol shows promise in reducing subsequent memory for new or recalled emotional material in healthy subjects. Studies of clinical populations, however, have yet to independently demonstrate that such findings can translate into powerful clinical effects.
Author: Federico Bermudez-Rattoni Publisher: CRC Press ISBN: 1420008412 Category : Psychology Languages : en Pages : 368
Book Description
A comprehensive, multidisciplinary review, Neural Plasticity and Memory: From Genes to Brain Imaging provides an in-depth, up-to-date analysis of the study of the neurobiology of memory. Leading specialists share their scientific experience in the field, covering a wide range of topics where molecular, genetic, behavioral, and brain imaging techniq
Author: National Academy of Sciences Publisher: National Academies Press ISBN: 0309045290 Category : Medical Languages : en Pages : 195
Book Description
The brain ... There is no other part of the human anatomy that is so intriguing. How does it develop and function and why does it sometimes, tragically, degenerate? The answers are complex. In Discovering the Brain, science writer Sandra Ackerman cuts through the complexity to bring this vital topic to the public. The 1990s were declared the "Decade of the Brain" by former President Bush, and the neuroscience community responded with a host of new investigations and conferences. Discovering the Brain is based on the Institute of Medicine conference, Decade of the Brain: Frontiers in Neuroscience and Brain Research. Discovering the Brain is a "field guide" to the brainâ€"an easy-to-read discussion of the brain's physical structure and where functions such as language and music appreciation lie. Ackerman examines: How electrical and chemical signals are conveyed in the brain. The mechanisms by which we see, hear, think, and pay attentionâ€"and how a "gut feeling" actually originates in the brain. Learning and memory retention, including parallels to computer memory and what they might tell us about our own mental capacity. Development of the brain throughout the life span, with a look at the aging brain. Ackerman provides an enlightening chapter on the connection between the brain's physical condition and various mental disorders and notes what progress can realistically be made toward the prevention and treatment of stroke and other ailments. Finally, she explores the potential for major advances during the "Decade of the Brain," with a look at medical imaging techniquesâ€"what various technologies can and cannot tell usâ€"and how the public and private sectors can contribute to continued advances in neuroscience. This highly readable volume will provide the public and policymakersâ€"and many scientists as wellâ€"with a helpful guide to understanding the many discoveries that are sure to be announced throughout the "Decade of the Brain."
Author: Michelle H. Lonergan Publisher: Elsevier Inc. Chapters ISBN: 0128057971 Category : Psychology Languages : en Pages : 32
Book Description
Background: Considering the pivotal role of negative emotional experiences in the development and persistence of mental disorders, effectively interfering with the consolidation/reconsolidation of such experiences would open the door to a novel treatment approach in psychiatry. Objective: We assessed the current evidence regarding the capacity of the β-blocker propranolol to block the consolidation/reconsolidation of emotional memories by means of a meta-analytic review. Data sources: An extensive multilingual literature search from 1994 to 2011 yielded 189 potential articles. Study selection: Selected studies consisted of randomized, double-blind experiments assessing long-term memory for emotional material in adults and involving at least one propranolol and one placebo condition. Of 189 potential studies, 13 consolidation ( n = 310) and 9 reconsolidation ( n = 327) experiments with adults met inclusion criteria for statistical analysis. Data extraction: Two independent reviewers extracted outcome and descriptive data from each study. Effect sizes were calculated using a random effects model. Data synthesis: Compared to placebo, propranolol given before memory consolidation reduced subsequent recall for negatively valenced stories, pictures, word lists, and the expression of cue-elicited fear responses: Hedge’s g = 0.47, 95% CI = 0.22–0.72. Moreover, compared to placebo, propranolol before memory reconsolidation reduced subsequent recall for negatively valenced emotional words, as well as the expression of cue-elicited fear responses, g = 0.59, 95% CI = 0.16–1.01. Splitting the results according to episodic retention and physiological responding did not yield a significant difference in effect size for consolidation or reconsolidation blockade. Removing the clinical studies from the larger group of nonclinical studies did not impact the statistical significance of the results either. Conclusions: Propranolol shows promise in reducing subsequent memory for new or recalled emotional material in healthy subjects. Studies of clinical populations, however, have yet to independently demonstrate that such findings can translate into powerful clinical effects.
Author: Edward D. Levin Publisher: CRC Press ISBN: 1420004336 Category : Medical Languages : en Pages : 395
Book Description
The costs associated with a drug's clinical trials are so significant that it has become necessary to validate both its safety and efficacy in animal models prior to the continued study of the drug in humans. Featuring contributions from distinguished researchers in the field of cognitive therapy research, Animal Models of Cognitive Impairmen
Author: Elizabeth A. Phelps Publisher: Elsevier Inc. Chapters ISBN: 0128057947 Category : Psychology Languages : en Pages : 41
Book Description
This chapter provides a comprehensive review of research on reconsolidation in humans to date. It examines the different techniques that have been used to explore memory reconsolidation in humans and highlights some of the unique challenges that arise when investigating reconsolidation in human participants. Through this survey of existing studies, we explore some of the reasons why this science has been slow to emerge, and we suggest some potential avenues for future research.
Author: David Appelbaum Publisher: State University of New York Press ISBN: 0791495094 Category : Philosophy Languages : en Pages : 204
Book Description
This book is about the disruption of the intellect that awakens consciousness to its wholeness and purpose. When consciousness is fractured, its world-making powers are momentarily disrupted. In the gap, during which spatio-temporal categories of thought cease to apply, consciousness realigns with that which it is meant to serve. The moment of self-remembering—shocking, unique, and truthful—leaves a call to obedience in its wake. To refuse to respond is to cease to be human.
Author: Thomas J. Anastasio Publisher: MIT Press ISBN: 0262544008 Category : Science Languages : en Pages : 347
Book Description
An argument that individuals and collectives form memories by analogous processes and a case study of collective retrograde amnesia. We form individual memories by a process known as consolidation: the conversion of immediate and fleeting bits of information into a stable and accessible representation of facts and events. These memories provide a version of the past that helps us navigate the present and is critical to individual identity. In this book, Thomas Anastasio, Kristen Ann Ehrenberger, Patrick Watson, and Wenyi Zhang propose that social groups form collective memories by analogous processes. Using facts and insights from neuroscience, psychology, anthropology, and history, they describe a single process of consolidation with analogous—not merely comparable—manifestations on any level, whether brain, family, or society. They propose a three-in-one model of memory consolidation, composed of a buffer, a relator, and a generalizer, all within the consolidating entity, that can explain memory consolidation phenomena on individual and collective levels. When consolidation is disrupted by traumatic injury to a brain structure known as the hippocampus, memories in the process of being consolidated are lost. In individuals, this is known as retrograde amnesia. The authors hypothesize a "social hippocampus" and argue that disruption at the collective level can result in collective retrograde amnesia. They offer the Chinese Cultural Revolution (1966–1976) as an example of trauma to the social hippocampus and present evidence for the loss of recent collective memory in mainland Chinese populations that experienced the Cultural Revolution.
Author: Viviana Beatriz MacManus Publisher: University of Illinois Press ISBN: 0252052412 Category : Social Science Languages : en Pages : 295
Book Description
The histories of the Dirty Wars in Mexico and Argentina (1960s–1980s) have largely erased how women experienced and remember the gendered violence during this traumatic time. Viviana Beatriz MacManus restores women to the revolutionary struggle at the heart of the era by rejecting both state projects and the leftist accounts focused on men. Using a compelling archival blend of oral histories, interviews, human rights reports, literature, and film, MacManus illuminates complex narratives of loss, violence, and trauma. The accounts upend dominant histories by creating a feminist-centered body of knowledge that challenges the twinned legacies of oblivion for the victims and state-sanctioned immunity for the perpetrators. A new Latin American feminist theory of justice emerges—one that acknowledges women's strength, resistance, and survival during and after a horrific time in their nations' histories. Haunting and methodologically innovative, Disruptive Archives attests to the power of women's storytelling and memory in the struggle to reclaim history.
Author: Michelle H. Lonergan
Author: Federico Bermudez-Rattoni
Author: National Academy of Sciences
Author: Michelle H. Lonergan
Author: Edward D. Levin
Author: Elizabeth A. Phelps
Author: David Appelbaum
Author: Neir Eshel
Author: Thomas J. Anastasio
Author: Viviana Beatriz MacManus
Author: Mark A. Krause