Disposition of Toxic Drugs and Chemicals in Man PDF Download

Author: Randall Clint Baselt
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 944

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Author: Randall C. Baselt
Publisher:
ISBN:
Category : Drug metabolism
Languages : en
Pages : 826

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Author: Randall Baselt
Publisher:
ISBN: 9780692774991
Category : Drugs
Languages : en
Pages : 0

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Book Description
The purpose of this work is to present in a single convenient source the current essential information on the disposition of the chemicals and drugs most frequently encountered in episodes of human poisoning. The data included relate to the body fluid concentrations of substances in normal or therapeutic situations, concentrations in fluids and tissues in instances of toxicity and the known metabolic fate of these substances in man. It is expected that such information will be of particular interest and use to toxicologists, pharmacologists, clinical chemists and clinicians who have need either to conduct an analytical search for these materials in specimens of human origin

Author: Randall Clint Baselt
Publisher:
ISBN:
Category : Drugs
Languages : en
Pages : 320

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Author: Randall Clint Baselt
Publisher: Biomedical Pubilcations
ISBN: 9780962652363
Category : Medical
Languages : en
Pages : 1254

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Discussions include occurrence and usage, blood concentrations, metabolism and excretion, toxicity, analysis and bibliographic references.

Author: Randall C. Baselt
Publisher:
ISBN: 9780931890017
Category : Drugs
Languages : en
Pages : 306

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Author: Randall C. Baselt
Publisher:
ISBN: 9780931890024
Category :
Languages : en
Pages : 0

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Author: B. Levine
Publisher:
ISBN:
Category : Drugs
Languages : en
Pages : 1

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Book Description
It has been over 15 years since the first edition of Baselt's "Disposition of Toxic Drugs and Chemicals in Man" was published and it is hard to imagine the practice of forensic toxicology without this valuable resource. Over the years, from the first edition to the current fourth edition, several changes have occurred. The organization of the book has changed, from a two volume set divided into centrally acting drugs and peripherally acting/other toxicants to its current alphabetical listing of toxicants. Beginning with the third edition and continuing with this edition, Robert Cravey has joined Dr. Baselt as a co-editor. Most dramatically, the number of toxic substances has more than doubled, from less than 200 in the first edition to over 400 in the fourth edition.

Author: Robert J. Flanagan
Publisher: John Wiley & Sons
ISBN: 0470319348
Category : Science
Languages : en
Pages : 605

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Book Description
The analytical toxicologist may be required to detect, identify, and in many cases measure a wide variety of compounds in samples from almost any part of the body or in related materials such as residues in syringes or in soil. This book gives principles and practical information on the analysis of drugs and poisons in biological specimens, particularly clinical and forensic specimens. After providing some background information the book covers aspects of sample collection, transport, storage and disposal, and sample preparation. Analytical techniques - colour tests and spectrophotometry, chromatography and electro­phoresis, mass spectrometry, and immunoassay – are covered in depth, and a chapter is devoted to the analysis of trace elements and toxic metals. General aspects of method implementation/validation and laboratory operation are detailed, as is the role of the toxicology laboratory in validating and monitoring the performance of point of care testing (POCT) devices. The book concludes with reviews of xenobiotic absorption, distribution and metabolism, pharmacokinetics, and general aspects of the interpretation of analytical toxicology results. A clearly written, practical, integrated approach to the basics of analytical toxicology. Focuses on analytical, statistical and pharmacokinetic principles rather than detailed applications. Assumes only a basic knowledge of analytical chemistry. An accompanying website provides additional material and links to related sites. Written by an experienced team of authors,Fundamentals of Analytical Toxicology is an invaluable resource for those starting out in a career in analytical toxicology across a wide range of disciplines including clinical and forensic science, food safety, and pharmaceutical development. Praise from the reviews: “This is an ambitious effort to describe in detail the many and varied aspects of the science of toxicological analysis. The 17 chapters cover every foreseeable aspect, from specimen collection through analytical techniques and quality control to pharmacological principles and interpretation of results. The authors bring together a great deal of experience in the field and have succeeded admirably in achieving their goal: "to give principles and practical information on the analysis of drugs, poisons and other relevant analytes in biological specimens...". The book is very readable and quite up-to-date, and contains many illustrative figures, charts and tables. Both the student and the practicing professional would do well to study this material carefully, as there is something here for every conceivable level of interest.” Review from Randall Baselt "This text comes highly recommended for any analytical toxicology trainee." The Bulletin of the Royal College of Pathologists “Overall, this book provides a comprehensive, thorough, clear, up to date and practical treatment of analytical toxicology at a high standard. Understanding of the text is enhanced by the use of many illustrations. Specifications, guidelines, and methods are highlighted in grey background “Boxes”. The many and up to date literature references in each chapter demonstrate the authors’ thorough work and permit easy access to deeper information. Therefore this book can be highly recommended as a valuable source of knowledge in analytical toxicology both as an introduction and for the advanced reader.” GTFCh Bulletin “Toxichem + Krimtech”, May 2008 (translated, original review in German) “Many toxicologists will add this important reference to their libraries because it competently fills a need ...” International Journal of Toxicology “The book is very well illustrated, easy to understand and pleasant to read, and contains a wealth of dedicated information.” International Journal of Environmental Analytical Chemistry

Author: RH. Cravey
Publisher:
ISBN:
Category : Drugs
Languages : en
Pages : 1

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Book Description
This second edition of Disposition of Toxic Drugs and Chemicals in Man will be a welcome addition to the reference library of those involved in the analytical and interpretative aspects of forensic toxicology. It has been four years since the first edition and during that time an overwhelming number of studies have appeared in the literature on the fate of drugs and other toxic chemicals in man as well as on new methods for the analysis of these substances and their metabolites from biofluids. Dr. Baselt has thoroughly reviewed the literature and critically selected the essential information to include in each monograph.