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Author: Ian Hughes Publisher: John Hunt Publishing ISBN: 1785358812 Category : Psychology Languages : en Pages : 208
Book Description
Disordered Minds offers a compelling and timely account of the dangers posed by narcissistic leaders, and provides a stark warning that the conditions in which this psychopathy flourishes - extremes of social inequality and a culture of hyper-individualism - are the hallmarks of our present age. 'An excellent account of how malignant narcissism is evident in the lives of the great dictators, and how the conditions in which this psychopathy flourishes have returned to haunt us.' Dr Kieran Keohane, editor of The Social Pathologies of Contemporary Civilization
Author: Ian Hughes Publisher: John Hunt Publishing ISBN: 1785358812 Category : Psychology Languages : en Pages : 208
Book Description
Disordered Minds offers a compelling and timely account of the dangers posed by narcissistic leaders, and provides a stark warning that the conditions in which this psychopathy flourishes - extremes of social inequality and a culture of hyper-individualism - are the hallmarks of our present age. 'An excellent account of how malignant narcissism is evident in the lives of the great dictators, and how the conditions in which this psychopathy flourishes have returned to haunt us.' Dr Kieran Keohane, editor of The Social Pathologies of Contemporary Civilization
Author: Robert Harris Publisher: Routledge ISBN: 1134679882 Category : Medical Languages : en Pages : 192
Book Description
Managing the Mentally Disordered Offender presses the case for better health care of mentally disturbed law breakers, and the need to divert them from unnecessary imprisonment. Mentally disordered offenders present particular problems in our society, which wants both to sympathise and to punish. How do we get the balance right between sympathy towards their illness and genuine worries about their offending behaviour? What do we do for - and about - people wo have been released from prison yet we suspect continue to pose risks to the safety of others? With specialist contributors from criminology, criminal justice, social work, probation practice and the law, Managing the Mentally Disordered Offender stresses the importance of professional cooperation in community-based services, whilst acknowledgin the psychologically demanding nature of working with mentally disordered people, and ther very real challenges of attempting to contain their wrongdoing without recourse to the repressiveness of imprisonment.
Author: Peter Tompa Publisher: CRC Press ISBN: 1420078933 Category : Science Languages : en Pages : 362
Book Description
The existence and functioning of intrinsically disordered proteins (IDPs) challenge the classical structure-function paradigm that equates function with a well-defined 3D structure. Uncovering the disordered complement of proteomes and understanding their functioning can extend the structure-function paradigm to herald new breakthroughs in drug dev
Author: Nicola Salvi Publisher: Academic Press ISBN: 0128167327 Category : Science Languages : en Pages : 355
Book Description
Intrinsically Disordered Proteins: Dynamics, Binding, and Function thoroughly examines and ties together the fundamental biochemical functions of intrinsically disordered proteins (IDPs) and intrinsically disordered regions (IDRs), including signaling, binding, and regulation, with the methodology for study and the associated pathways for drug design and therapeutic intervention. The role of new mechanistic, computational, and experimental approaches in IDP study are explored in depth, with methods for the characterization of IDP dynamics; models, simulations, and mechanisms of IDP and IDR binding; and biological and medical implications of IDP dynamics prominently featured. Written and edited by leading scientists in the field, this book explores groundbreaking areas such as ensemble descriptions of IDPs and IDRs, single-molecule studies of IDPs and IDRs, IDPs and IDRs in membraneless organelles, and molecular mechanisms of fibrillation of IDPs. Intrinsically Disordered Proteins provides students and researchers in biochemistry, molecular biology, and applied microbiology with a comprehensive and updated discussion of the complex dynamics of IDPs and IDRs. Provides in-depth discussion of fundamental IDP and IDR dynamics, function, and binding, with mechanistic insight to support new drug development Describes the role of new computational and experimental approaches in characterizing the binding of IDPs to their functional targets Features chapter contributions from international experts in IDP and IDR biochemical function and methods of study
Author: Vladimir N. Uversky Publisher: Springer ISBN: 3319089218 Category : Science Languages : en Pages : 73
Book Description
In this brief, Vladimir Uversky discusses the paradigm-shifting phenomenon of intrinsically disordered proteins (IDPs) and hybrid proteins containing ordered domains and functional IDP regions (IDPRs). Beginning with an introduction to the concept of protein intrinsic disorder, Uversky then goes on to describe the peculiar amino acid sequences of IDPs, their structural heterogeneity, typical functions and disorder-based binding modes. In the final sections, Uversky discusses IDPs in human diseases and as potential drug targets. This volume provides a snapshot to researchers entering the field as well as providing a current overview for more experienced scientists in related areas.
Author: Publisher: Academic Press ISBN: 0128156503 Category : Science Languages : en Pages : 754
Book Description
Intrinsically Disordered Proteins, Volume 611, the latest release in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on topics of interest, including the Characterization of Structure-Function relationships in the intrinsically disordered protein complexin, Distances, distance distributions, and ensembles of IDPs from single-molecule FRET, Biophysical characterization of disordered protein liquid phases, The Use of Mass Spectrometry to Examine IDPs – Unique Insights and Caveats, Fluorescence Depolarization Kinetics to Study Conformational Preference, Structural Plasticity and Membrane Binding of Intrinsically Disordered Proteins, Characterizing the Function of Intrinsically Disordered Proteins in the Circadian Clock, and more. Breadth of experimental approaches and systems that will be covered The expertise of the contributors writing the articles
Author: David C. S. Richard Publisher: John Wiley & Sons ISBN: 0470710713 Category : Psychology Languages : en Pages : 485
Book Description
The Wiley-Blackwell Handbook of Disordered Gambling is a complete guide to the current empirical literature relating to the conceptualization, assessment, and treatment of disordered gambling. The international contributors are all experienced, practicing clinicians who discuss gambling within a global context. Best-practice guidelines for the clinical management of problem and disordered gambling Contains empirically derived findings that translate research into practical clinical applications that clinicians and counselors can use in understanding and treating problem gamblers Brings together a distinguished international group of scholars whose contributions discuss gambling as it occurs around the globe Clearly organized into sections that cover conceptualization, research, assessment, treatment, and special topics
Author: S. K. Tripathi Publisher: Alpha Science Int'l Ltd. ISBN: 9788173194634 Category : Science Languages : en Pages : 292
Book Description
Proceedings of the National Conference on "Recent Developments on Disordered Materials", held in Dept. of Physics, Panjab University, Chandigarh, on 15-16 March, 2001; contributed papers.
Author: Sheilagh Hodgins Publisher: John Wiley & Sons ISBN: 0471977276 Category : Psychology Languages : en Pages : 260
Book Description
The mentally disordered criminal is a public nightmare, and themanagement of these offenders can be driven as much by politicaland economic concerns as by scientific evidence and professionaljudgement within the fields of mental health and correctionservices. This book aims to provide a critical and focused reviewof knowledge and best practice in this field for mental health andcorrection professionals and for those concerned with policy andmanagement of services for these offenders. Mentally disordered offenders include offenders who suffer fromschizophrenia, major affective disorders, personality disorders(including psychopathy), brain damage, and mental retardation. Thetopic is of increasing importance because of the growth ofcommunity psychiatry, and the growing community programmes foroffenders, and also because of the growing pressures on thoseinstitutions which deal with offenders and care for the mentallydisordered or disabled. Professionals in these fields will welcomethis book which: * Provides a review of approaches to treatment, accessible to awide mental health and forensic readership * Relates treatment approaches to specific mental problems, andreviews evidence of effectiveness * features a truly international group of authors bringing togethera wide variety of approaches, scientific research, and practicalexperience of important programmes for treatment and prevention "Few recent texts provide both the depth and breadth necessary tounderstand the vexing behaviour of mentally disordered offenders.Drs Hodgins and Muller-Isberner, a remarkable pairing of researchand clinical expertise, have put together a highly readable andsuperb resource for anyone interested in this interface of seriousmental illness and criminal behavior. The authors of theconstituent chapters are leading authorities in their respectiveareas and have provided thoughtful commentary on the most recentinternational literature. This is a first-rate treatment of arapidly growing and fascinating field." Marvin Swartz, DukeUniversity, USA
Author: Ian Hughes
Author: Ian Hughes
Author: Robert Harris
Author: Peter Tompa
Author: Joseph Sciambra
Author: Nicola Salvi
Author: Vladimir N. Uversky
Author: 
Author: David C. S. Richard
Author: S. K. Tripathi
Author: Sheilagh Hodgins