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Evolution in Health and Disease

Evolution in Health and Disease PDF Author: Stephen C. Stearns
Publisher: Oxford University Press, USA
ISBN:
Category : Adaptation (Physiology)
Languages : en
Pages : 352

Book Description
Have you ever wondered how the disparity between the life experiences of our ancestors and ourselves might affect our health? For the majority of our evolutionary history, humans lived in small hunter- gatherer groups whose diet, lifestyle, living conditions, and environmental pressures werevery different to the experiences of most humans today. The adaptations making us uniquely human - height, brain size, body proportions, metabolic rate, day range - were established during the Pleistocene - some 200 times as long as our recent evolutionary history - and may not fit us as well atthe end of the 20th Century. This fascinating book explores and analyses the ways in which our ancient genes contend with, and influence, human life in the space age. It offers the first broad, in-depth coverage of the many points of contact between evolutionary biology and medical science.Evolutionary biology is not a standard part of medical education, but it offers many important insights into central problems of human health and disease. These include the evolution of antibiotic resistance, the evolution of pathogen virulence, the evolution of ageing, the design of vaccines, andpopulation- and genotype-specific reactions to drugs and susceptibility to disease. They also include new insights into mother-offspring conflict during pregnancy, menstruation, menopause, child abuse, homicide, depression, schizophrenia, and many chronic degenerative diseases, such as cancer andosteoporosis. This book, written by a team of world experts in evolutionary medicine, describes the state of the art, and provides easy, clear access to the primary literature. Addressed to medical students, medical researchers, and evolutionary biologists, it provides compelling arguments for whythe tools of evolutionary biology - both its ideas and its methods - belong in every doctor's tool-kit.

Evolution in Health and Disease

Evolution in Health and Disease PDF Author: Stephen C. Stearns
Publisher: Oxford University Press, USA
ISBN:
Category : Adaptation (Physiology)
Languages : en
Pages : 352

Book Description
Have you ever wondered how the disparity between the life experiences of our ancestors and ourselves might affect our health? For the majority of our evolutionary history, humans lived in small hunter- gatherer groups whose diet, lifestyle, living conditions, and environmental pressures werevery different to the experiences of most humans today. The adaptations making us uniquely human - height, brain size, body proportions, metabolic rate, day range - were established during the Pleistocene - some 200 times as long as our recent evolutionary history - and may not fit us as well atthe end of the 20th Century. This fascinating book explores and analyses the ways in which our ancient genes contend with, and influence, human life in the space age. It offers the first broad, in-depth coverage of the many points of contact between evolutionary biology and medical science.Evolutionary biology is not a standard part of medical education, but it offers many important insights into central problems of human health and disease. These include the evolution of antibiotic resistance, the evolution of pathogen virulence, the evolution of ageing, the design of vaccines, andpopulation- and genotype-specific reactions to drugs and susceptibility to disease. They also include new insights into mother-offspring conflict during pregnancy, menstruation, menopause, child abuse, homicide, depression, schizophrenia, and many chronic degenerative diseases, such as cancer andosteoporosis. This book, written by a team of world experts in evolutionary medicine, describes the state of the art, and provides easy, clear access to the primary literature. Addressed to medical students, medical researchers, and evolutionary biologists, it provides compelling arguments for whythe tools of evolutionary biology - both its ideas and its methods - belong in every doctor's tool-kit.

Diseases and Human Evolution

Diseases and Human Evolution PDF Author: Ethne Barnes
Publisher: UNM Press
ISBN: 0826330673
Category : Medical
Languages : en
Pages : 500

Book Description
Urgent interest in new diseases, such as the coronavirus, and the resurgence of older diseases like tuberculosis has fostered questions about the history of human infectious diseases. How did they evolve? Where did they originate? What natural factors have stalled the progression of diseases or made them possible? How does a microorganism become a pathogen? How have infectious diseases changed through time? What can we do to control their occurrence? ; Ethne Barnes offers answers to these questions, using information from history and medicine as well as from anthropology. She focuses on changes in the patterns of human behavior through cultural evolution and how they have affected the development of human diseases. ; Writing in a clear, lively style, Barnes offers general overviews of every variety of disease and their carriers, from insects and worms through rodent vectors to household pets and farm animals. She devotes whole chapters to major infectious diseases such as leprosy, syphilis, smallpox, and influenza. Other chapters concentrate on categories of diseases ("gut bugs," for example, including cholera, typhus, and salmonella). The final chapters cover diseases that have made headlines in recent years, among them mad cow disease, West Nile virus, and Lyme disease. ; In the tradition of Berton Roueché, Hans Zinsser, and Sherwin Nuland, Ethne Barnes answers questions you never knew you had about the germs that have threatened us throughout human history.

Genetics and Evolution of Infectious Diseases

Genetics and Evolution of Infectious Diseases PDF Author: Michel Tibayrenc
Publisher: Elsevier
ISBN: 0123848903
Category : Medical
Languages : en
Pages : 773

Book Description
Genetics and Evolution of Infectious Diseases is at the crossroads between two major scientific fields of the 21st century: evolutionary biology and infectious diseases. The genomic revolution has upset modern biology and has revolutionized our approach to ancient disciplines such as evolutionary studies. In particular, this revolution is profoundly changing our view on genetically driven human phenotypic diversity, and this is especially true in disease genetic susceptibility. Infectious diseases are indisputably the major challenge of medicine. When looking globally, they are the number one killer of humans and therefore the main selective pressure exerted on our species. Even in industrial countries, infectious diseases are now far less under control than 20 years ago. The first part of this book covers the main features and applications of modern technologies in the study of infectious diseases. The second part provides detailed information on a number of the key infectious diseases such as malaria, SARS, avian flu, HIV, tuberculosis, nosocomial infections and a few other pathogens that will be taken as examples to illustrate the power of modern technologies and the value of evolutionary approaches. Takes an integrated approach to infectious diseases Includes contributions from leading authorities Provides the latest developments in the field

Evolution and Disease

Evolution and Disease PDF Author: James Thomas Charles Nash
Publisher:
ISBN:
Category : Diseases
Languages : en
Pages : 90

Book Description


Evolution in Health and Disease

Evolution in Health and Disease PDF Author: Stephen C. Stearns
Publisher: Oxford University Press
ISBN: 9780199207459
Category : Medical
Languages : en
Pages : 398

Book Description
This work explores and analyses the ways in which our ancient genes contend with, and influence, modern human life. It offers coverage of the points of contact between evolutionary biology and medical science.

Malaria

Malaria PDF Author: Krishna R. Dronamraju
Publisher: Springer Science & Business Media
ISBN: 0387282955
Category : Science
Languages : en
Pages : 198

Book Description
This book was originally conceived at a conference at the University of Turin in Italy. The conference was organized to examine the so-called “Malaria Hypothesis”, that is to say, the higher fitness of t- lassemia heterozygotes in a malarial environment, and to pay tribute to the proponent of that hypothesis, J.B.S. Haldane. Contributors to this book examine certain genetic and evolutionary aspects of malaria which is a major killer of human populations, especially in Africa and Asia. There were attempts to discredit Haldane’s contribution from two directions: (a) it has been suggested that the “Malaria Hypothesis” was known long before Haldane and that there was nothing original about his idea (Lederberg 1999), and that (b) the hypothesis of heterozygote su- riority was first suggested by the Italian biologist Giuseppe Montalenti who communicated his idea to Haldane (Allison 2004). Surely, both c- not be right. In fact, the evidence presented in this book clearly indicates that both are wrong. Haldane’s malaria hypothesis has stimulated a great deal of research on the genetic, evolutionary and epidemiological aspects of malaria d- ing the last 50 years. It has opened up a whole new chapter in the study of infectious diseases. It deserves serious consideration. For helpful discussions we thank Lucio Luzzatto, Alberto Piazza, Guido Modiano and David Roberts.

The Story of the Human Body

The Story of the Human Body PDF Author: Daniel Lieberman
Publisher: Vintage
ISBN: 030774180X
Category : Science
Languages : en
Pages : 482

Book Description
A landmark book of popular science that gives us a lucid and engaging account of how the human body evolved over millions of years—with charts and line drawings throughout. “Fascinating.... A readable introduction to the whole field and great on the making of our physicality.”—Nature In this book, Daniel E. Lieberman illuminates the major transformations that contributed to key adaptations to the body: the rise of bipedalism; the shift to a non-fruit-based diet; the advent of hunting and gathering; and how cultural changes like the Agricultural and Industrial Revolutions have impacted us physically. He shows how the increasing disparity between the jumble of adaptations in our Stone Age bodies and advancements in the modern world is occasioning a paradox: greater longevity but increased chronic disease. And finally—provocatively—he advocates the use of evolutionary information to help nudge, push, and sometimes even compel us to create a more salubrious environment and pursue better lifestyles.

Genetics and Evolution of Infectious Diseases

Genetics and Evolution of Infectious Diseases PDF Author: Michel Tibayrenc
Publisher: Elsevier
ISBN: 0443288194
Category : Medical
Languages : en
Pages : 1002

Book Description
Genetics and Evolution of Infectious Diseases, Third Edition discusses the evolving field of infectious diseases and their continued impact on the health of populations, especially in resource-limited areas of the world where they must confront the dual burden of death and disability due to infectious and chronic illnesses. Although substantial gains have been made in public health interventions for the treatment, prevention, and control of infectious diseases, in recent decades the world has witnessed the emergence of the human immunodeficiency virus (HIV) and the COVID-19 pandemic, increasing antimicrobial resistance, and the emergence of many new bacterial, fungal, parasitic, and viral pathogens. Fully updated and revised, this new edition presents the consequences of such diseases, the evolution of infectious diseases, the genetics of host-pathogen relationship, and the control and prevention strategies that are, or can be, developed. This book offers valuable information to biomedical researchers, clinicians, public health practitioners, decisions-makers, and students and postgraduates studying infectious diseases, microbiology, medicine, and public health that is relevant to the control and prevention of neglected and emerging worldwide diseases. Takes an integrated approach to infectious diseases Provides the latest developments in the field of infectious diseases Focuses on the contribution of evolutionary and genomic studies for the study and control of transmissible diseases Includes updated and revised contributions from leading authorities, along with six new chapters

Principles of Evolutionary Medicine

Principles of Evolutionary Medicine PDF Author: Peter D. Gluckman
Publisher: Oxford University Press
ISBN: 0199663939
Category : Medical
Languages : en
Pages : 401

Book Description
A new updated edition of the first integrated and comprehensive textbook to explain the principles of evolutionary biology from a medical perspective and to focus on how medicine and public health might utilise evolutionary biology.

Disease Selection

Disease Selection PDF Author: Roger Webber
Publisher: CABI
ISBN: 1780646828
Category : Medical
Languages : en
Pages : 193

Book Description
Disease Selection: The way disease changed the world explores the host-pathogen relationship and the way communicable diseases have evolved often to stay one step ahead of interventions. From sexually transmitted disease through to ancient and modern great plagues, parasites, food, zoonoses, climate change and populations, this book explores the way disappeared and emergent diseases have shaped our world just as much as nature has. This book provides key information and is a valuable resource for students, practitioners and researchers working in global health and anyone interested in understanding of the basis of disease.