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Disease and Discovery

Disease and Discovery PDF Author: Elizabeth Fee
Publisher: Johns Hopkins University Press+ORM
ISBN: 1421421127
Category : Medical
Languages : en
Pages : 480

Book Description
The story of a world-renowned institution and “a broad investigation of early twentieth-century public health ideology in America” (Journal of the American Medical Association). At the end of the nineteenth century, public health was the province of part-time political appointees and volunteer groups of every variety. Public health officers were usually physicians, but they could also be sanitary engineers, lawyers, or chemists—there was little agreement about the skills and knowledge necessary for practice. In Disease and Discovery, Elizabeth Fee examines the conflicting ideas about public health’s proper subject and scope and its search for a coherent professional unity and identity. She draws on the debates and decisions surrounding the establishment of what was initially known as the Johns Hopkins School of Hygiene and Public Health, the first independent institution for public health research and education, to crystallize the fundamental questions of the field. Many of the issues of public health education in the early twentieth century are still debated today. What is the proper relationship of public health to medicine? What is the relative importance of biomedical, environmental, and sociopolitical approaches to public health? Should schools of public health emphasize research skills over practical training? Should they provide advanced training and credentials for the few or simpler educational courses for the many? Fee explores the many dimensions of these issues in the context of the founding of the Johns Hopkins school. She details the efforts to define the school’s structure and purpose, select faculty and students, and organize the curriculum, and she follows the school’s growth and adaptation to the changing social environment through the beginning of World War II. As Fee demonstrates, not simply in its formation but throughout its history, the School of Hygiene served as a crucible for the forces shaping the public health profession as a whole.

Disease and Discovery

Disease and Discovery PDF Author: Elizabeth Fee
Publisher: Johns Hopkins University Press+ORM
ISBN: 1421421127
Category : Medical
Languages : en
Pages : 480

Book Description
The story of a world-renowned institution and “a broad investigation of early twentieth-century public health ideology in America” (Journal of the American Medical Association). At the end of the nineteenth century, public health was the province of part-time political appointees and volunteer groups of every variety. Public health officers were usually physicians, but they could also be sanitary engineers, lawyers, or chemists—there was little agreement about the skills and knowledge necessary for practice. In Disease and Discovery, Elizabeth Fee examines the conflicting ideas about public health’s proper subject and scope and its search for a coherent professional unity and identity. She draws on the debates and decisions surrounding the establishment of what was initially known as the Johns Hopkins School of Hygiene and Public Health, the first independent institution for public health research and education, to crystallize the fundamental questions of the field. Many of the issues of public health education in the early twentieth century are still debated today. What is the proper relationship of public health to medicine? What is the relative importance of biomedical, environmental, and sociopolitical approaches to public health? Should schools of public health emphasize research skills over practical training? Should they provide advanced training and credentials for the few or simpler educational courses for the many? Fee explores the many dimensions of these issues in the context of the founding of the Johns Hopkins school. She details the efforts to define the school’s structure and purpose, select faculty and students, and organize the curriculum, and she follows the school’s growth and adaptation to the changing social environment through the beginning of World War II. As Fee demonstrates, not simply in its formation but throughout its history, the School of Hygiene served as a crucible for the forces shaping the public health profession as a whole.

Scurvy

Scurvy PDF Author: Jonathan Lamb
Publisher: Princeton University Press
ISBN: 0691182930
Category : History
Languages : en
Pages : 322

Book Description
An intellectual history of scurvy in the eighteenth century Scurvy—a disease usually associated with long stretches of maritime travel—generated extraordinary sensations. Eyes dazzled, skin was morbidly sensitive, emotions veered between disgust and delight. In this book, Jonathan Lamb presents an intellectual history of scurvy unlike any other, probing its cultural impact during the eighteenth-century age of geographic and scientific discovery. Drawing on historical accounts from scientists and voyagers as well as major literary works, Lamb explains the medical knowledge surrounding scurvy and the debates about its cause, prevention, and attempted cures. He argues that a “culture” of scurvy arose in the colony of Australia, which was prey to the disease in its early years, and identifies a literature of scurvy in the works of such figures as Herman Melville, Samuel Taylor Coleridge, Francis Bacon, and Jonathan Swift. Masterful and illuminating, Scurvy shows how eighteenth-century journeys of discovery not only ventured outward to the ends of the earth, but were also an inward voyage into the realms of sensation and passion.

Genomics

Genomics PDF Author: Hans C. Andersson, MD
Publisher: Millbrook Press
ISBN: 1728411580
Category : Young Adult Nonfiction
Languages : en
Pages : 139

Book Description
Over the past 50 years, scientists have made incredible progress in the application of genetic research to human health care and disease treatment. Innovative tools and techniques, including gene therapy and CRISPR-Cas9 editing, can treat inherited disorders that were previously untreatable, or prevent them from happening in the first place. You can take a DNA test to learn where your ancestors are from. Police officers can use genetic evidence to identify criminals—or innocents. And some doctors are using new medical techniques for unprecedented procedures. Genomics: A Revolution in Health and Disease Discovery delves into the history, science, and ethics behind recent breakthroughs in genetic research. Authors Whitney Stewart and Hans Andersson, MD, present fascinating case studies that show how real people have benefitted from genetic research. Though the genome remains full of mysteries, researchers and doctors are working hard to uncover its secrets and find the best ways to treat patients and cure diseases. The discoveries to come will inform how we target disease treatment, how we understand our health, and how we define our very identities.

Scurvy

Scurvy PDF Author: Jonathan Lamb
Publisher: Princeton University Press
ISBN: 0691182930
Category : History
Languages : en
Pages : 322

Book Description
An intellectual history of scurvy in the eighteenth century Scurvy—a disease usually associated with long stretches of maritime travel—generated extraordinary sensations. Eyes dazzled, skin was morbidly sensitive, emotions veered between disgust and delight. In this book, Jonathan Lamb presents an intellectual history of scurvy unlike any other, probing its cultural impact during the eighteenth-century age of geographic and scientific discovery. Drawing on historical accounts from scientists and voyagers as well as major literary works, Lamb explains the medical knowledge surrounding scurvy and the debates about its cause, prevention, and attempted cures. He argues that a “culture” of scurvy arose in the colony of Australia, which was prey to the disease in its early years, and identifies a literature of scurvy in the works of such figures as Herman Melville, Samuel Taylor Coleridge, Francis Bacon, and Jonathan Swift. Masterful and illuminating, Scurvy shows how eighteenth-century journeys of discovery not only ventured outward to the ends of the earth, but were also an inward voyage into the realms of sensation and passion.

Disease and Discovery

Disease and Discovery PDF Author: Eva Bailey
Publisher: Trafalgar Square Publishing
ISBN: 9780713446333
Category : Diseases
Languages : en
Pages : 72

Book Description


The Deep Places

The Deep Places PDF Author: Ross Douthat
Publisher: Convergent Books
ISBN: 0593237366
Category : Biography & Autobiography
Languages : en
Pages : 225

Book Description
NEW YORK TIMES EDITORS’ CHOICE • In this vulnerable, insightful memoir, the New York Times columnist tells the story of his five-year struggle with a disease that officially doesn’t exist, exploring the limits of modern medicine, the stories that we unexpectedly fall into, and the secrets that only suffering reveals. “A powerful memoir about our fragile hopes in the face of chronic illness.”—Kate Bowler, bestselling author of Everything Happens for a Reason In the summer of 2015, Ross Douthat was moving his family, with two young daughters and a pregnant wife, from Washington, D.C., to a sprawling farmhouse in a picturesque Connecticut town when he acquired a mysterious and devastating sickness. It left him sleepless, crippled, wracked with pain--a shell of himself. After months of seeing doctors and descending deeper into a physical inferno, he discovered that he had a disease which according to CDC definitions does not actually exist: the chronic form of Lyme disease, a hotly contested condition that devastates the lives of tens of thousands of people but has no official recognition--and no medically approved cure. From a rural dream house that now felt like a prison, Douthat's search for help takes him off the map of official medicine, into territory where cranks and conspiracies abound and patients are forced to take control of their own treatment and experiment on themselves. Slowly, against his instincts and assumptions, he realizes that many of the cranks and weirdos are right, that many supposed "hypochondriacs" are victims of an indifferent medical establishment, and that all kinds of unexpected experiences and revelations lurk beneath the surface of normal existence, in the places underneath. The Deep Places is a story about what happens when you are terribly sick and realize that even the doctors who are willing to treat you can only do so much. Along the way, Douthat describes his struggle back toward health with wit and candor, portraying sickness as the most terrible of gifts. It teaches you to appreciate the grace of ordinary life by taking that life away from you. It reveals the deep strangeness of the world, the possibility that the reasonable people might be wrong, and the necessity of figuring out things for yourself. And it proves, day by dreadful day, that you are stronger than you ever imagined, and that even in the depths there is always hope.

Madness and Memory

Madness and Memory PDF Author: Stanley B. Prusiner
Publisher: Yale University Press
ISBN: 0300191146
Category : Science
Languages : en
Pages : 344

Book Description
The author, a 1997 recipient of the Noble Prize in medicine, describes the years he spent researching and demonstrating how the infectious proteins known as prions were responsible for brain diseases and how his theory has now become widely accepted in the science establishment.

Drug Design and Discovery in Alzheimer’s Disease

Drug Design and Discovery in Alzheimer’s Disease PDF Author: Atta-ur Rahman
Publisher: Elsevier
ISBN: 0128039604
Category : Medical
Languages : en
Pages : 785

Book Description
Drug Design and Discovery in Alzheimer’s Disease includes expert reviews of recent developments in Alzheimer's disease (AD) and neurodegenerative disease research. Originally published by Bentham as Frontiers in Drug Design and Discovery, Volume 6and now distributed by Elsevier, this compilation of the sixteen articles, written by leading global researchers, focuses on key developments in the understanding of the disease at molecular levels, identification and validation of molecular targets, as well as innovative approaches towards drug discovery, development, and delivery. Beginning with an overview of AD pharmacotherapy and existing blockbuster drugs, the reviews cover the potential of both natural and synthetic small molecules; the role of cholinesterases in the on-set and progression of AD and their inhibition; the role of beta-site APP clearing enzyme-1 (BACE-1) in the production of ß-amyloid proteins, one of the key reasons of the progression of AD; and other targets identified for AD drug discovery. Edited and written by leading experts in Alzheimer’s disease (AD) and other neurodegenerative disease drug development Describes existing drugs for AD and current molecular understanding of the condition Reviews recent advances in the field, including coverage of cholinesterases, BACE-1, and other drug development targets

Parasites and Infectious Disease

Parasites and Infectious Disease PDF Author: Gerald Esch
Publisher: Cambridge University Press
ISBN: 9780521675390
Category : Medical
Languages : en
Pages : 372

Book Description
Engaging introduction to the key discoveries that have shaped the field of parasitology.

Discovery and Development of Therapeutics from Natural Products Against Neglected Tropical Diseases

Discovery and Development of Therapeutics from Natural Products Against Neglected Tropical Diseases PDF Author: Goutam Brahmachari
Publisher: Elsevier
ISBN: 0128157240
Category : Medical
Languages : en
Pages : 458

Book Description
Discovery and Development of Therapeutics from Natural Products against Neglected Tropical Diseases draws together research on medicinal agents from natural sources as starting points for the design of drugs against Neglected Tropical Diseases (NTDs). From the prediction of promising leads and identification of active agents, to the extraction of complex molecules, the book explores novel, economical and efficacious therapeutics for these diseases. It describes current research and the role of natural products, antimalarial compounds from marine natural products and sesquiterpene lactones, natural antileprotic agents, natural products with potential against Leishmaniasis, Trypanosomiasis and Dengue, and more. In addition, Quinoline and Isoquinoline alkaloids for developing new antiprotozoal agents are discussed, alongside anti-trypanosomatid heterocyclic compounds as structures for development. Combining the expertise of specialists from around the world, this volume aims to support and encourage researchers in the investigation of natural sources as starting points for the development of novel, safe and effective agents for use against neglected tropical diseases. Includes chapters written by active researchers and leading global experts deeply engaged in the research field of natural product chemistry for drug discovery Draws together cutting-edge research advances in natural product chemistry that are targeted at neglected tropical diseases Highlights the future potential of natural products as sources of novel medicinal compounds against neglected tropical diseases