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Study Design and Statistical Analysis

Study Design and Statistical Analysis PDF Author: Mitchell Katz
Publisher: Cambridge University Press
ISBN: 1139643738
Category : Medical
Languages : en
Pages : 229

Book Description
This book takes the reader through the entire research process: choosing a question, designing a study, collecting the data, using univariate, bivariate and multivariable analysis, and publishing the results. It does so by using plain language rather than complex derivations and mathematical formulae. It focuses on the nuts and bolts of performing research by asking and answering the most basic questions about doing research studies. Making good use of numerous tables, graphs and tips, this book helps to demystify the process. A generous number of up-to-date examples from the clinical literature give an illustrated and practical account of how to use multivariable analysis.

Optimal Design of Experiments

Optimal Design of Experiments PDF Author: Peter Goos
Publisher: John Wiley & Sons
ISBN: 1119976162
Category : Science
Languages : en
Pages : 249

Book Description
"This is an engaging and informative book on the modern practice of experimental design. The authors' writing style is entertaining, the consulting dialogs are extremely enjoyable, and the technical material is presented brilliantly but not overwhelmingly. The book is a joy to read. Everyone who practices or teaches DOE should read this book." - Douglas C. Montgomery, Regents Professor, Department of Industrial Engineering, Arizona State University "It's been said: 'Design for the experiment, don't experiment for the design.' This book ably demonstrates this notion by showing how tailor-made, optimal designs can be effectively employed to meet a client's actual needs. It should be required reading for anyone interested in using the design of experiments in industrial settings." —Christopher J. Nachtsheim, Frank A Donaldson Chair in Operations Management, Carlson School of Management, University of Minnesota This book demonstrates the utility of the computer-aided optimal design approach using real industrial examples. These examples address questions such as the following: How can I do screening inexpensively if I have dozens of factors to investigate? What can I do if I have day-to-day variability and I can only perform 3 runs a day? How can I do RSM cost effectively if I have categorical factors? How can I design and analyze experiments when there is a factor that can only be changed a few times over the study? How can I include both ingredients in a mixture and processing factors in the same study? How can I design an experiment if there are many factor combinations that are impossible to run? How can I make sure that a time trend due to warming up of equipment does not affect the conclusions from a study? How can I take into account batch information in when designing experiments involving multiple batches? How can I add runs to a botched experiment to resolve ambiguities? While answering these questions the book also shows how to evaluate and compare designs. This allows researchers to make sensible trade-offs between the cost of experimentation and the amount of information they obtain.

Case Study Research

Case Study Research PDF Author: John Gerring
Publisher: Cambridge University Press
ISBN: 1316857808
Category : Social Science
Languages : en
Pages : 441

Book Description
Case Study Research: Principles and Practices provides a general understanding of the case study method as well as specific tools for its successful implementation. These tools are applicable in a variety of fields including anthropology, business and management, communications, economics, education, medicine, political science, psychology, social work, and sociology. Topics include: a survey of case study approaches; a methodologically tractable definition of 'case study'; strategies for case selection, including random sampling and other algorithmic approaches; quantitative and qualitative modes of case study analysis; and problems of internal and external validity. The second edition of this core textbook is designed to be accessible to readers who are new to the subject and is thoroughly revised and updated, incorporating recent research, numerous up-to-date studies and comprehensive lecture slides.

Study Design and Statistical Analysis

Study Design and Statistical Analysis PDF Author: Mitchell Katz
Publisher: Cambridge University Press
ISBN: 1139643738
Category : Medical
Languages : en
Pages : 229

Book Description
This book takes the reader through the entire research process: choosing a question, designing a study, collecting the data, using univariate, bivariate and multivariable analysis, and publishing the results. It does so by using plain language rather than complex derivations and mathematical formulae. It focuses on the nuts and bolts of performing research by asking and answering the most basic questions about doing research studies. Making good use of numerous tables, graphs and tips, this book helps to demystify the process. A generous number of up-to-date examples from the clinical literature give an illustrated and practical account of how to use multivariable analysis.

Design Representation

Design Representation PDF Author: Gabriela Goldschmidt
Publisher: Springer Science & Business Media
ISBN: 1852338636
Category : Technology & Engineering
Languages : en
Pages : 232

Book Description
"...there is a global network of academics, researchers and methodologists who will buy this book or want it in their institute libraries.” Prof. John Harbraken "As the field of human computer interaction grows, this book is likely to be a basic resource.” Prof. Chuck Eastman Design representation is necessary for all design activity. You will gain a guide to both theory and practical application in this discussion of representation as it occurs during the process of design. Goldschmidt and Porter give you perspectives on representational issues in design that are both informative and evocative of further inquiry. The unique interdisciplinary approach brings a new dimension to the study of representation, benefiting the global network of researchers, students and practitioners in all areas of design. Rather than addressing the larger framework directly, a series of smaller case studies are presented, each dealing with aspects of representation in architecture and engineering. Binding together historical-cultural, cognitive-social and technological perspectives eliminates the need for further reading. Innovative research methods based on numerous well-illustrated examples will leave you with new ideas to build on. International contributors focus on worldwide research activities, offering you more than just an expansion of a single viewpoint. Design Representation delves into the common roots of representation in all design disciplines through case studies, historical investigations, theoretical constructs and programming. If you are involved in any design activity, this will be a truly exciting addition to your bookshelf.

Designing Your Life

Designing Your Life PDF Author: Bill Burnett
Publisher: Knopf
ISBN: 110187533X
Category : Self-Help
Languages : en
Pages : 274

Book Description
#1 NEW YORK TIMES BEST SELLER • At last, a book that shows you how to build—design—a life you can thrive in, at any age or stage • “Life has questions. They have answers.” —The New York Times Designers create worlds and solve problems using design thinking. Look around your office or home—at the tablet or smartphone you may be holding or the chair you are sitting in. Everything in our lives was designed by someone. And every design starts with a problem that a designer or team of designers seeks to solve. In this book, Bill Burnett and Dave Evans show us how design thinking can help us create a life that is both meaningful and fulfilling, regardless of who or where we are, what we do or have done for a living, or how young or old we are. The same design thinking responsible for amazing technology, products, and spaces can be used to design and build your career and your life, a life of fulfillment and joy, constantly creative and productive, one that always holds the possibility of surprise.

Design Study

Design Study PDF Author: J. F. Cage
Publisher:
ISBN:
Category : Sodium cooled reactors
Languages : en
Pages : 786

Book Description
This study was undertaken for the USAEC under Contract AT(04-3)-189, Project Agreement No. 6, to investigate desirable features of a sodium cooled, graphite moderated uranium fueled power reactor using the modular concept, and, based on this investigation, evaluate the economic potential of this reactor type.

Clinical Trials

Clinical Trials PDF Author: Tom Brody
Publisher: Academic Press
ISBN: 0123919134
Category : Medical
Languages : en
Pages : 673

Book Description
Clinical Trials: Study Design, Endpoints and Biomarkers, Drug Safety, and FDA and ICH Guidelines is a practical guidebook for those engaged in clinical trial design. This book details the organizations and content of clinical trials, including trial design, safety, endpoints, subgroups, HRQoL, consent forms and package inserts. It provides extensive information on both US and international regulatory guidelines and features concrete examples of study design from the medical literature. This book is intended to orient those new to clinical trial design and provide them with a better understanding of how to conduct clinical trials. It will also act as a guide for the more experienced by detailing endpoint selection and illustrating how to avoid unnecessary pitfalls. This book is a straightforward and valuable reference for all those involved in clinical trial design. - Provides extensive coverage of the "study schema" and related features of study design - Offers a "hands-on" reference that contains an overview of the process, but more importantly details a step-by-step account of clinical trial design - Features examples from the medical literature to highlight how investigators choose the most suitable endpoint(s) for clinical trial and includes graphs from real clinical trials to help explain each concept in study design - Integrates clinical trial design, pharmacology, biochemistry, cell biology and legal aspects to provide readers with a comprehensive look at all aspects of clinical trials - Includes chapters on core material and important ancillary topics, such as package inserts, consent forms, and safety reporting forms used in the United States, England and Europe - For complimentary access to our sample chapter (chapter 24), please copy and paste this link into your browser: http://tinyurl.com/awwutvn

Understanding by Design

Understanding by Design PDF Author: Grant P. Wiggins
Publisher: ASCD
ISBN: 1416600353
Category : Education
Languages : en
Pages : 383

Book Description
What is understanding and how does it differ from knowledge? How can we determine the big ideas worth understanding? Why is understanding an important teaching goal, and how do we know when students have attained it? How can we create a rigorous and engaging curriculum that focuses on understanding and leads to improved student performance in today's high-stakes, standards-based environment? Authors Grant Wiggins and Jay McTighe answer these and many other questions in this second edition of Understanding by Design. Drawing on feedback from thousands of educators around the world who have used the UbD framework since its introduction in 1998, the authors have greatly revised and expanded their original work to guide educators across the K-16 spectrum in the design of curriculum, assessment, and instruction. With an improved UbD Template at its core, the book explains the rationale of backward design and explores in greater depth the meaning of such key ideas as essential questions and transfer tasks. Readers will learn why the familiar coverage- and activity-based approaches to curriculum design fall short, and how a focus on the six facets of understanding can enrich student learning. With an expanded array of practical strategies, tools, and examples from all subject areas, the book demonstrates how the research-based principles of Understanding by Design apply to district frameworks as well as to individual units of curriculum. Combining provocative ideas, thoughtful analysis, and tested approaches, this new edition of Understanding by Design offers teacher-designers a clear path to the creation of curriculum that ensures better learning and a more stimulating experience for students and teachers alike.

The Study of Architectural Design

The Study of Architectural Design PDF Author: John Frederick Harbeson
Publisher: New York : Pencil Points Press
ISBN:
Category : Architectural design
Languages : en
Pages : 336

Book Description


Epidemiology

Epidemiology PDF Author: Mark Woodward
Publisher: CRC Press
ISBN: 1482243202
Category : Mathematics
Languages : en
Pages : 844

Book Description
Highly praised for its broad, practical coverage, the second edition of this popular text incorporated the major statistical models and issues relevant to epidemiological studies. Epidemiology: Study Design and Data Analysis, Third Edition continues to focus on the quantitative aspects of epidemiological research. Updated and expanded, this edition shows students how statistical principles and techniques can help solve epidemiological problems. New to the Third Edition New chapter on risk scores and clinical decision rules New chapter on computer-intensive methods, including the bootstrap, permutation tests, and missing value imputation New sections on binomial regression models, competing risk, information criteria, propensity scoring, and splines Many more exercises and examples using both Stata and SAS More than 60 new figures After introducing study design and reviewing all the standard methods, this self-contained book takes students through analytical methods for both general and specific epidemiological study designs, including cohort, case-control, and intervention studies. In addition to classical methods, it now covers modern methods that exploit the enormous power of contemporary computers. The book also addresses the problem of determining the appropriate size for a study, discusses statistical modeling in epidemiology, covers methods for comparing and summarizing the evidence from several studies, and explains how to use statistical models in risk forecasting and assessing new biomarkers. The author illustrates the techniques with numerous real-world examples and interprets results in a practical way. He also includes an extensive list of references for further reading along with exercises to reinforce understanding. Web Resource A wealth of supporting material can be downloaded from the book’s CRC Press web page, including: Real-life data sets used in the text SAS and Stata programs used for examples in the text SAS and Stata programs for special techniques covered Sample size spreadsheet