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Author: Vadim Komkov Publisher: Academic Press ISBN: 0080960006 Category : Technology & Engineering Languages : en Pages : 399
Book Description
The book is organized into four chapters. The first three treat distinct types of design variables, and the fourth presents a built-up structure formulation that combines the other three. The first chapter treats finite-dimensional problems, in which the state variable is a finite-dimensional vector of structure displacements and the design parameters. The structual state equations are matrix equations for static response, vibration, and buckling of structures and matrix differential equations for transient dynamic response of structures, which design variables appearing in the coefficient matrices.
Author: Vadim Komkov Publisher: Academic Press ISBN: 0080960006 Category : Technology & Engineering Languages : en Pages : 399
Book Description
The book is organized into four chapters. The first three treat distinct types of design variables, and the fourth presents a built-up structure formulation that combines the other three. The first chapter treats finite-dimensional problems, in which the state variable is a finite-dimensional vector of structure displacements and the design parameters. The structual state equations are matrix equations for static response, vibration, and buckling of structures and matrix differential equations for transient dynamic response of structures, which design variables appearing in the coefficient matrices.
Author: Mark W. Lipsey Publisher: SAGE ISBN: 9780803930636 Category : Business & Economics Languages : en Pages : 216
Book Description
All researchers face an important challenge - designing research that will have sufficient sensitivity to detect those effects it purports to investigate. Through careful explanations and selection of examples, this title examines the concept of design sensitivity and explains statistical power and the elements that determine it.
Author: Agency for Health Care Research and Quality (U.S.) Publisher: Government Printing Office ISBN: 1587634236 Category : Medical Languages : en Pages : 236
Book Description
This User’s Guide is a resource for investigators and stakeholders who develop and review observational comparative effectiveness research protocols. It explains how to (1) identify key considerations and best practices for research design; (2) build a protocol based on these standards and best practices; and (3) judge the adequacy and completeness of a protocol. Eleven chapters cover all aspects of research design, including: developing study objectives, defining and refining study questions, addressing the heterogeneity of treatment effect, characterizing exposure, selecting a comparator, defining and measuring outcomes, and identifying optimal data sources. Checklists of guidance and key considerations for protocols are provided at the end of each chapter. The User’s Guide was created by researchers affiliated with AHRQ’s Effective Health Care Program, particularly those who participated in AHRQ’s DEcIDE (Developing Evidence to Inform Decisions About Effectiveness) program. Chapters were subject to multiple internal and external independent reviews. More more information, please consult the Agency website: www.effectivehealthcare.ahrq.gov)
Author: Andrea Saltelli Publisher: John Wiley & Sons ISBN: 047087094X Category : Mathematics Languages : en Pages : 232
Book Description
Sensitivity analysis should be considered a pre-requisite for statistical model building in any scientific discipline where modelling takes place. For a non-expert, choosing the method of analysis for their model is complex, and depends on a number of factors. This book guides the non-expert through their problem in order to enable them to choose and apply the most appropriate method. It offers a review of the state-of-the-art in sensitivity analysis, and is suitable for a wide range of practitioners. It is focussed on the use of SIMLAB – a widely distributed freely-available sensitivity analysis software package developed by the authors – for solving problems in sensitivity analysis of statistical models. Other key features: Provides an accessible overview of the current most widely used methods for sensitivity analysis. Opens with a detailed worked example to explain the motivation behind the book. Includes a range of examples to help illustrate the concepts discussed. Focuses on implementation of the methods in the software SIMLAB - a freely-available sensitivity analysis software package developed by the authors. Contains a large number of references to sources for further reading. Authored by the leading authorities on sensitivity analysis.
Author: Andrea Saltelli Publisher: John Wiley & Sons ISBN: 9780470725177 Category : Mathematics Languages : en Pages : 304
Book Description
Complex mathematical and computational models are used in all areas of society and technology and yet model based science is increasingly contested or refuted, especially when models are applied to controversial themes in domains such as health, the environment or the economy. More stringent standards of proofs are demanded from model-based numbers, especially when these numbers represent potential financial losses, threats to human health or the state of the environment. Quantitative sensitivity analysis is generally agreed to be one such standard. Mathematical models are good at mapping assumptions into inferences. A modeller makes assumptions about laws pertaining to the system, about its status and a plethora of other, often arcane, system variables and internal model settings. To what extent can we rely on the model-based inference when most of these assumptions are fraught with uncertainties? Global Sensitivity Analysis offers an accessible treatment of such problems via quantitative sensitivity analysis, beginning with the first principles and guiding the reader through the full range of recommended practices with a rich set of solved exercises. The text explains the motivation for sensitivity analysis, reviews the required statistical concepts, and provides a guide to potential applications. The book: Provides a self-contained treatment of the subject, allowing readers to learn and practice global sensitivity analysis without further materials. Presents ways to frame the analysis, interpret its results, and avoid potential pitfalls. Features numerous exercises and solved problems to help illustrate the applications. Is authored by leading sensitivity analysis practitioners, combining a range of disciplinary backgrounds. Postgraduate students and practitioners in a wide range of subjects, including statistics, mathematics, engineering, physics, chemistry, environmental sciences, biology, toxicology, actuarial sciences, and econometrics will find much of use here. This book will prove equally valuable to engineers working on risk analysis and to financial analysts concerned with pricing and hedging.
Author: National Research Council Publisher: National Academies Press ISBN: 030918651X Category : Medical Languages : en Pages : 163
Book Description
Randomized clinical trials are the primary tool for evaluating new medical interventions. Randomization provides for a fair comparison between treatment and control groups, balancing out, on average, distributions of known and unknown factors among the participants. Unfortunately, these studies often lack a substantial percentage of data. This missing data reduces the benefit provided by the randomization and introduces potential biases in the comparison of the treatment groups. Missing data can arise for a variety of reasons, including the inability or unwillingness of participants to meet appointments for evaluation. And in some studies, some or all of data collection ceases when participants discontinue study treatment. Existing guidelines for the design and conduct of clinical trials, and the analysis of the resulting data, provide only limited advice on how to handle missing data. Thus, approaches to the analysis of data with an appreciable amount of missing values tend to be ad hoc and variable. The Prevention and Treatment of Missing Data in Clinical Trials concludes that a more principled approach to design and analysis in the presence of missing data is both needed and possible. Such an approach needs to focus on two critical elements: (1) careful design and conduct to limit the amount and impact of missing data and (2) analysis that makes full use of information on all randomized participants and is based on careful attention to the assumptions about the nature of the missing data underlying estimates of treatment effects. In addition to the highest priority recommendations, the book offers more detailed recommendations on the conduct of clinical trials and techniques for analysis of trial data.
Author: Emmanuel Laporte Publisher: Springer Science & Business Media ISBN: 1461200695 Category : Technology & Engineering Languages : en Pages : 202
Book Description
Sensitivity analysis and optimal shape design are key issues in engineering that have been affected by advances in numerical tools currently available. This book, and its supplementary online files, presents basic optimization techniques that can be used to compute the sensitivity of a given design to local change, or to improve its performance by local optimization of these data. The relevance and scope of these techniques have improved dramatically in recent years because of progress in discretization strategies, optimization algorithms, automatic differentiation, software availability, and the power of personal computers. Numerical Methods in Sensitivity Analysis and Shape Optimization will be of interest to graduate students involved in mathematical modeling and simulation, as well as engineers and researchers in applied mathematics looking for an up-to-date introduction to optimization techniques, sensitivity analysis, and optimal design.
Author: Assem Deif Publisher: Springer Science & Business Media ISBN: 364282739X Category : Technology & Engineering Languages : en Pages : 235
Book Description
A text surveying perturbation techniques and sensitivity analysis of linear systems is an ambitious undertaking, considering the lack of basic comprehensive texts on the subject. A wide-ranging and global coverage of the topic is as yet missing, despite the existence of numerous monographs dealing with specific topics but generally of use to only a narrow category of people. In fact, most works approach this subject from the numerical analysis point of view. Indeed, researchers in this field have been most concerned with this topic, although engineers and scholars in all fields may find it equally interesting. One can state, without great exaggeration, that a great deal of engineering work is devoted to testing systems' sensitivity to changes in design parameters. As a rule, high-sensitivity elements are those which should be designed with utmost care. On the other hand, as the mathematical modelling serving for the design process is usually idealized and often inaccurately formulated, some unforeseen alterations may cause the system to behave in a slightly different manner. Sensitivity analysis can help the engineer innovate ways to minimize such system discrepancy, since it starts from the assumption of such a discrepancy between the ideal and the actual system.
Author: J. A. Jurado Publisher: WIT Press ISBN: 184564056X Category : Technology & Engineering Languages : en Pages : 369
Book Description
This book is dedicated to the study of an aeroelastic phenomenon of cable supported long span bridges known as flutter, and proposes very innovative design methodologies, such as sensitivity analysis and optimization techniques, already utilized successfully in automobile and aerospace industries. The topic of long-span suspension and cable-stayed bridges is currently of great importance. These types of bridge pose great technical difficulties due to their slenderness and often great dimension. Therefore, these bridges tend to have problems caused by natural forces such as wind loads, some of which we have witnessed in our history, and we are currently seeing a very high incidence of bridge construction to overcome geographical obstacles such as bays, straits, or great estuaries. Therefore, it seems very appropriate to write a book showing the current capability of analysis and design, when up until now, the information could only be found partially in technical articles. This book will be useful for bridge design engineers as well as researchers working in the field. This book only requires previous knowledge of structural finite element models and dynamics, and it is advisable to have some previous knowledge in bridge engineering. Nevertheless, this book is very self-contained in such a way that all the information necessary to understand the theoretical developments is presented without the need of additional bibliography.
Author: Vadim Komkov
Author: Vadim Komkov
Author: Mark W. Lipsey
Author: Agency for Health Care Research and Quality (U.S.)
Author: Andrea Saltelli
Author: Andrea Saltelli
Author: National Research Council
Author: Emmanuel Laporte
Author: Assem Deif
Author: J. A. Jurado
Author: Lisa G. Stanley