Author: Wenlin Lee
Publisher:
ISBN:
Category :
Languages : en
Pages : 282
Book Description
Design and Synthesis of Novel [beta]-Lactam Antibiotics
Design and Synthesis of Novel Monocylic Beta-lactam as Antimycobacterial Agents
Author: Amal Amry
Publisher:
ISBN:
Category : Beta lactam antibiotics
Languages : en
Pages : 94
Book Description
Publisher:
ISBN:
Category : Beta lactam antibiotics
Languages : en
Pages : 94
Book Description
The Synthesis of Novel Compounds Related to Beta-lactam Antibiotics
Synthesis of β-Lactam Antibiotics
Author: Alle Bruggink
Publisher: Springer Science & Business Media
ISBN: 9401008507
Category : Science
Languages : en
Pages : 328
Book Description
Penicillins and cephalosporins have a long history in combating bacterial infections. Despite new infectious diseases and occurring resistance, beta-lactam antibiotics will for many years to come continue to play a prominent role in our therapeutic arsenal. This book covers the industrial development of the chemical and biochemical processes used to manufacture these products, as well as looking ahead to possible future processes. The interplay between synthetic organic chemistry with the understanding and application of enzymes, modeling of fermentation processes and integration through (bio-) chemical process engineering is illustrated. In-depth scientific approaches to biocatalysis and biocatalyst development including enzyme kinetics, enzyme crystal studies and semi-rational enzyme mutations are also presented. Metabolic pathway analysis and modeling of fermentation process are treated as well as molecular precision in synthetic approaches to beta-lactams, their precursors and derivatives. Process technology studies including new reactor concepts, possible short-cut routes and improved down-stream-processing methods complete a broad view on the scope and limitations of the presently developed industrial processes including an intriguing insight into future process possibilities. This book represents an excellent case study on the transformation of traditional, stoïchiometric, organic synthesis and classical fermentations into modern (bio-) catalysis and biosynthesis based on insights in metabolic pathways and enzyme actions.
Publisher: Springer Science & Business Media
ISBN: 9401008507
Category : Science
Languages : en
Pages : 328
Book Description
Penicillins and cephalosporins have a long history in combating bacterial infections. Despite new infectious diseases and occurring resistance, beta-lactam antibiotics will for many years to come continue to play a prominent role in our therapeutic arsenal. This book covers the industrial development of the chemical and biochemical processes used to manufacture these products, as well as looking ahead to possible future processes. The interplay between synthetic organic chemistry with the understanding and application of enzymes, modeling of fermentation processes and integration through (bio-) chemical process engineering is illustrated. In-depth scientific approaches to biocatalysis and biocatalyst development including enzyme kinetics, enzyme crystal studies and semi-rational enzyme mutations are also presented. Metabolic pathway analysis and modeling of fermentation process are treated as well as molecular precision in synthetic approaches to beta-lactams, their precursors and derivatives. Process technology studies including new reactor concepts, possible short-cut routes and improved down-stream-processing methods complete a broad view on the scope and limitations of the presently developed industrial processes including an intriguing insight into future process possibilities. This book represents an excellent case study on the transformation of traditional, stoïchiometric, organic synthesis and classical fermentations into modern (bio-) catalysis and biosynthesis based on insights in metabolic pathways and enzyme actions.
Design and Synthesis of Novel Triple Action NO-containing Monocyclic Beta-lactams
Author: Allison Lauren Blum
Publisher:
ISBN:
Category : Beta lactam antibiotics
Languages : en
Pages : 88
Book Description
Publisher:
ISBN:
Category : Beta lactam antibiotics
Languages : en
Pages : 88
Book Description
The synthesis of novel compounds related to β-lactam antibiotics
Novel Beta-Lactam Inhibitors Design -- Synthesis and Modeling Study
Synthesis of Novel [beta]-lactam Conjugates as New Antibiotic Antineoplastic Agents
Author: Julkernine Mohammad Khondoker
Publisher:
ISBN:
Category :
Languages : en
Pages : 314
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 314
Book Description
Beta-Lactams
Author: Bimal K. Banik
Publisher: Springer
ISBN: 3319556215
Category : Science
Languages : en
Pages : 423
Book Description
This book presents an essential overview of beta-lactams and their medicinal value and use in the preparation of other biologically active compounds. Written by internationally respected authors, the individual chapters explore beta-lactams’ synthesis, their mechanism of formation, biological effects, and function as base materials for other heterocycles of major importance.
Publisher: Springer
ISBN: 3319556215
Category : Science
Languages : en
Pages : 423
Book Description
This book presents an essential overview of beta-lactams and their medicinal value and use in the preparation of other biologically active compounds. Written by internationally respected authors, the individual chapters explore beta-lactams’ synthesis, their mechanism of formation, biological effects, and function as base materials for other heterocycles of major importance.
The Chemistry of [beta]-lactams
Author: Michael I. Page
Publisher: Springer Science & Business Media
ISBN:
Category : Medical
Languages : en
Pages : 380
Book Description
This volume provides a review of developments in the chemistry of beta-lactams, particularly in the synthesis, reactivity and mechanisms of reaction, including novel beta-lactam structures and non-beta-lactam analogues.
Publisher: Springer Science & Business Media
ISBN:
Category : Medical
Languages : en
Pages : 380
Book Description
This volume provides a review of developments in the chemistry of beta-lactams, particularly in the synthesis, reactivity and mechanisms of reaction, including novel beta-lactam structures and non-beta-lactam analogues.