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Author: Ann Arvin Publisher: Cambridge University Press ISBN: 1139461648 Category : Medical Languages : en Pages : 1325
Book Description
This comprehensive account of the human herpesviruses provides an encyclopedic overview of their basic virology and clinical manifestations. This group of viruses includes human simplex type 1 and 2, Epstein–Barr virus, Kaposi's Sarcoma-associated herpesvirus, cytomegalovirus, HHV6A, 6B and 7, and varicella-zoster virus. The viral diseases and cancers they cause are significant and often recurrent. Their prevalence in the developed world accounts for a major burden of disease, and as a result there is a great deal of research into the pathophysiology of infection and immunobiology. Another important area covered within this volume concerns antiviral therapy and the development of vaccines. All these aspects are covered in depth, both scientifically and in terms of clinical guidelines for patient care. The text is illustrated generously throughout and is fully referenced to the latest research and developments.
Author: Ann Arvin Publisher: Cambridge University Press ISBN: 1139461648 Category : Medical Languages : en Pages : 1325
Book Description
This comprehensive account of the human herpesviruses provides an encyclopedic overview of their basic virology and clinical manifestations. This group of viruses includes human simplex type 1 and 2, Epstein–Barr virus, Kaposi's Sarcoma-associated herpesvirus, cytomegalovirus, HHV6A, 6B and 7, and varicella-zoster virus. The viral diseases and cancers they cause are significant and often recurrent. Their prevalence in the developed world accounts for a major burden of disease, and as a result there is a great deal of research into the pathophysiology of infection and immunobiology. Another important area covered within this volume concerns antiviral therapy and the development of vaccines. All these aspects are covered in depth, both scientifically and in terms of clinical guidelines for patient care. The text is illustrated generously throughout and is fully referenced to the latest research and developments.
Author: Thomas E. Shenk Publisher: Springer Science & Business Media ISBN: 3540773495 Category : Medical Languages : en Pages : 477
Book Description
This volume has gathered some of the experts in the field to review aspects of our understanding of CMV and to offer perspectives of the current problems associated with CMV. The editors and authors hope that the chapters will lead to a better understanding of the virus that will assist in the development of new and unique antivirals, a protective vaccine, and a full understanding of CMV's involvement in human disease.
Author: John E. Craighead Publisher: Academic Press ISBN: 0080538487 Category : Medical Languages : en Pages : 466
Book Description
Pathology and Pathogenesis of Human Viral Disease is a comprehensive reference that examines virus-induced clinical disease of humans in the context of the responsible virus and its epidemiology. Encompassing everything from cold and flu viruses to sexually transmitted diseases, this important resource describes the cellular and tissue pathological changes attributable to infection in the context of the pathogenic mechanisms involved. The author provides a comprehensive review of the older and contemporary literature, considering both the common and much rarer complications of infection. Pathology and Pathogenesis of Human Viral Disease is written from the unique perspective of the clinical pathologist. It will help clinicians and pathologists gain a better understanding of changes that occur in viral infected cells, tissues, and organs. It will also serve as a pathology source book for virologists, internists, and pediatricians. Provides a comprehensive, worldwide perspective of viral disease pathology Bridges the fields of pathology and virology; integrating clinical disease with cell and tissue pathology Addresses topics from the perspective of the clinical pathologist Illustrates unique, viral induced pathological lesions Considers common and uncommon complications of infection
Author: James K. McDougall Publisher: Springer Science & Business Media ISBN: 3642749801 Category : Medical Languages : en Pages : 280
Book Description
Named for the enlarged, inclusion-bearing cells characteristic of infection by these viruses, cytomegaloviruses present a significant challenge to both microbiologist and immunologist. Although most primary infections in humans are subclinical, cytomegalovirus can be associated with a wide spectrum of disease, particularly when infection occurs in the immuno compromised individual or as a result of congenital or perinatal infection. Although reinfection with cytomegalovirus has been demonstrated, most recurrent and persistent infections result from the reactivation of latent virus. Cytomegaloviruses, like other members of the Herpesviridae family, have the capacity to establish latency after a primary infection but the mechanisms for establishing the nonreplicating but reactivat able state have not been defined. The factors responsible for the spectrum of manifestations of cytomegalovirus infection are largely undetermined but host immunological function, route of infection, and size of inoculum all contribute to the extent and severity of disease. Cytomegaloviruses have the largest genomes in the herpes virus family, approximately 240 kilo base pairs, providing a potential coding capacity for more than 200 proteins of which less than one-fourth have been mapped and described. There are many similarities to other herpes viruses in genome structure and gene expression; for example, three temporal classes of genes can be identified as rx (immediate-early), f3 (early), and y (late) products. The first five chapters of this volume review and describe recent developments in understanding the trans cription and regulation of these gene classes.
Author: Matthias Johannes Reddehase Publisher: ISBN: 9781913652388 Category : Languages : en Pages :
Book Description
In this book leading international experts provide comprehensive and authoritative reviews on every aspect of current research. By integrating viral genomics, proteomics, immunology and molecular biology with the emerging knowledge of the genomics of the host organism, penetrating new insights into the virus-host interaction are provided. The focus of the book is on the molecular and genomic aspects and the authors provide an insight into the current understanding of the subject and the future direction of research. Topics covered include disease mechanisms, genomics, proteomics, BAC mutagenes.
Author: David W. Kimberlin Publisher: ISBN: 9781610025218 Category : Languages : en Pages : 1100
Book Description
The AAP's authoritative guide on preventing, recognizing, and treating more than 200 childhood infectious diseases. Developed by the AAP's Committee on Infectious Diseases as well as the expertise of the CDC, the FDA, and hundreds of physician contributors.
Author: National Center for Health Statistics (U.S.) Publisher: ISBN: Category : Medical Languages : en Pages : 420
Book Description
Describes the plan and operation of the third National Health and Nutrition Survey. The sample for this study of the U.S. population was selected from households in 81 counties across the United States. About 40,000 persons 2 months of age and over were selected, including large samples of both young and old persons. About 12,000 of the sample persons were black Americans, 12,000 were Mexican-Americans, and the remaining 16,000 were of all other race and ethnicity groups. All selected persons were asked to complete an extensive interview and an examination in a large mobile examination center. The survey period is 1988-94, consisting of two phases of equal length and sample size. Both Phase 1 and Phase 2 were random samples of the U.S. population living in households.
Author: Robert W Maitta Publisher: Elsevier Health Sciences ISBN: 0323544592 Category : Medical Languages : en Pages : 350
Book Description
Offering a concise overview of transfusion medicine, including best practices for specific clinical settings, this practical resource by Dr. Robert W. Maitta covers the key information you need to know. Holistic, multidisciplinary coverage and a succinct, easy-to-read format make it essential reading for transfusion specialists, as well as practitioners in other specialties whose patients undergo blood transfusions. Covers the latest advancements in transfusion therapies, hematopoietic stem cells, infectious and non-infectious complications of transfusions, and future directions in transfusion medicine. Discusses special populations, including organ transplant patients; pediatric, obstetric, and geriatric patients; and patients undergoing emergency care. Consolidates fundamental clinical concepts and current practice of transfusion medicine into one convenient resource.
Author: Per Ljungman Publisher: Springer ISBN: 3319287974 Category : Medical Languages : en Pages : 983
Book Description
As the number of patients undergoing hematotopoietic or solid organ transplantation increases, a deep understanding of the field of transplant infectious diseases grows increasingly vital. With its extensively revised and updated review of surgical infections, treatment, prevention, and practice, this book is the ultimate guide to advances in the field of transplant infections that are rapidly implemented into practice both in diagnostic technologies, new therapies, new transplant practices, and challenges such as the threat of multiresistant bacteria and the increasing use of transplantation in the developing parts of the world. Written by experts in their fields, this book is the only comprehensive source of cutting-edge information on transplant infections and has been a trusted guide to medical professionals worldwide for nearly two decades. Transplant Infections is of paramount value to infectious disease specialists, transplant physicians, medical students, fellows, residents, and all medical professionals working with surgical patients.
Author: Alfred S. Evans Publisher: Springer Science & Business Media ISBN: 1468447270 Category : Medical Languages : en Pages : 744
Book Description
also occurs. New outbreaks of yellow fever have occurred in Colombia and Trinidad and new outbreaks of rift valley fever have occurred in Egypt. Chapter 6, Arenaviruses: The biochemical and physical properties have now been clar ified, and they show a remarkable uniformity in the various viruses constituting the group. The possibility that prenatal infection with LCM may result in hydrocephalus and chorioretinitis has been raised. Serologic surveys have suggested the existence of Lassa virus infection in Guinea, Central African Empire, Mali, Senegal, Cameroon, and Benin, in addition to earlier identification in Nigeria, Liberia, and Sierra Leone. Chapter 7, Coronaviruses: New studies have confirmed the important role of these viruses in common respiratory illnesses of children and adults. The viruses are now known to contain a single positive strand of RNA. About 50% of corona virus infections result in clinical illness. About 5% of common colds are caused by strain DC 43 in winter. Chapter 8, Cytomegalovirus: Sections on pathogenesis of CMV in relation to organ transplantation and mononucleosis, as well as sections on the risk and features of con genital infection and disease, have been expanded. There are encouraging preliminary results with a live CMV vaccine, but the questions of viral persistence and oncogenicity require further evaluation.
Author: Ann Arvin
Author: Ann Arvin
Author: Thomas E. Shenk
Author: John E. Craighead
Author: James K. McDougall
Author: Matthias Johannes Reddehase
Author: David W. Kimberlin
Author: National Center for Health Statistics (U.S.)
Author: Robert W Maitta
Author: Per Ljungman
Author: Alfred S. Evans