Cytokine Cell Biology PDF Download

Author: Fran Balkwill
Publisher: OUP Oxford
ISBN: 0191566101
Category : Science
Languages : en
Pages : 288

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Book Description
Cytokine Cellular Biology focuses on cell biology techniques for studying cytokines, cytokine receptors, and cytokine driven processes. Assays for human B cell responses, leucocyte migration, haematopoietic growth factors, macrophage activation by cytokines, RIA, IRMA, and ELISA assays, and quantitative biological assays for cytokines are all covered in detail. There are also updated chapters on studying cytokine regulation of endothelial cells; the measurement of proliferative, cytostatic, and cytolytic activity of cytokines; and the development of antibodies to cytokines. In addition there is a new chapter on the use of flow ctyometry and intracellular fluorescent staining. Written by experts in the field, Cytokine Molecular Biology and Cytokine Cellular Biology form a comprehensive and essential guide to cytokine research.

Author: Joost J. Oppenheim
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 624

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Book Description
Cytokines are regulatory polypeptides synthesized by a variety of cells in response to injury, inflammation or infection and which act on different tissues by changing gene expression and cellular metabolism. This book provides the results from recent in vitro studies of the structure and function of various cytokines. It offers an up-to-date overview of the latest advances in cytokine research, including research developments dealing with colony stimulating factors, interferons and growth and differentiation factors - as well as classical hormones such as insulin, neurokinin, somatomedin and parathormones. Several newly identified cytokine receptor structures are also discussed, as are certain activities of the recently discovered 8,000-10,000 m.w. cytokine family.

Author: Fran Balkwill
Publisher: OUP Oxford
ISBN: 0191566098
Category : Science
Languages : en
Pages : 224

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Book Description
Cytokine Molecular Biology concentrates on molecular biology techniques for the study of cytokines, cytokine receptors, and cytokine driven processes. Updated topics from the previous edition are: the cloning and expressing cytokine genes;; the detection of cytokine mRNA; receptor binding studies; the PC-specific phosphslipase C and sphingomylinases. In addition, new topics covered are the purification, sequencing, and synthesis of cytokines; studying cytokine gene polymorphisms; the use of proteomics in cytokine research; and the Jak/STAT and MAPK signalling pathways. Written by experts in the field, Cytokine Molecular Biology and Cytokine Cellular Biology form a comprehensive and essential guide to cytokine research.

Author: Richard M. Ransohoff
Publisher: CRC Press
ISBN: 9780849316227
Category : Medical
Languages : en
Pages : 396

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Book Description
Provides Insight into How Cytokine Action Impacts the Physiology and Pathology of the CNS. As with the first edition of Cytokines and the CNS, this completely updated and revised edition introduces neurobiologists to cytokine biology and immunologists to the unique functions of cytokines in CNS physiology. The dramatically accelerating interest in cytokines and cytokine/chemokine signaling over the past several years has encouraged an explosion of literature on cytokines. The similarity between factors involved in inflammation or immunity, and those implicated in neural development, physiology, and repair has become so apparent that familiarity with cytokines must now be considered an essential element in the neurobiologist’s cognitive tool-kit. Conversely, for immunobiologists, the concepts elaborated by neurobiologists to understand developmental patterning and networked organ function continue to evolve in such a way that comprehension of cytokine action in the CNS can only enhance a further understanding of immune system function. Cytokines and the CNS, Second Edition is patterned after the first edition; however, the wealth of knowledge now available adds a tremendous amount of insight and new implications. To guarantee a fresh perspective, the editors made a conscious choice to utilize an entirely new set of contributors, all experts in various aspects of cytokine research. Cytokines and the CNS, Second Edition starts with a chapter on the CNS, focusing on pathological reactions to insult. Next, come three chapters on cytokine biology, followed by four chapters that integrate cytokine biology into basic CNS processes (development; inflammation; immunity; degeneration/repair), after which five chapters apply this body of knowledge to disease or pathology. The book closes with a look at the application of cytokine biology to the treatment of disease, a brand new area of research.

Author: Anthony R. Mire-Sluis
Publisher: Academic Press
ISBN: 0080530214
Category : Medical
Languages : en
Pages : 609

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Book Description
This book provides comprehensive coverage of the cytokines from a pharmacological approach. The chapters are presented in a consistent format allowing easy cross-reference, with sample diagrams and a summary table of essential facts for each chapter at the end of the book. Cytokines is unique in stressing cytokine biology and the application of research data to provide disease therapy. With 33 detailed and up-to-date chapters about individual cytokines, this comprehensive reference will provide both clinicians and researchers in immunology and pharmacology with invaluable information. Genetic information and sequences Protein structure Cell sources and production Biological activity Cytokine receptor structure and signal transduction Discussion of the role of cytokines in disease and the potential for therapy Summary table of essential facts Comprehensive bibliography

Author: Masoud H. Manjili
Publisher:
ISBN: 9781621009290
Category : Cytokines
Languages : en
Pages : 0

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Book Description
Cells of the immune system communicate with each other, and respond to abnormal conditions by releasing soluble proteins, named cytokines. Abnormal or dangerous conditions include infection, trauma and injury, neurological disorders, and cancer. The balance between pro- and anti-inflammatory cytokines can comfort or exacerbate the symptoms in these diseases. This book focuses on counter-regulatory and the role of cytokines in different diseases. The goal is to understand contribution of cytokines in the progression of the disease as well as therapeutic potential of cytokines in the treatment of the disease by understanding cytokine counter-regulation.

Author: Bruce Alberts
Publisher:
ISBN: 9780815332183
Category : Cytology
Languages : en
Pages : 0

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Book Description

Author: Rafael Fernandez-Botran
Publisher: CRC Press
ISBN: 1420041355
Category : Medical
Languages : en
Pages : 269

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Book Description
A step-by-step guide to commonly used procedures, Methods in Cellular Immunology addresses both human and murine models, in addition to such topics as PCR and apoptosis. The basic format of the original version has been maintained, and the goal remains the same: to make it a useful and easy-to-use tool for investigators employing cellular immunolog

Author: Constantin A. Bona
Publisher: CRC Press
ISBN: 0203305132
Category : Science
Languages : en
Pages : 864

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Book Description
The field of cytokine research is expanding at a rapid pace Contributions from the major leading groups in the world on the structure and biological properties of cytokine and cytokine receptors, as well as integrated reviews on cytokines in various physiological and pathological conditions were presented in three issues of International Reviews of Immunology This collection of articles provided a unique source of information However, important discoveries are emerging very rapidly and some of the reviews written in 1997 are already outdated In this book, the editors assemble reviews that have been updated by their authors to include all the recent publications and unpublished data from the authors' laboratories This volume should serve as an excellent reference source for all those concerned by the multiple faces of cytokines in basic research and in the clinic

Author: Zlatko Dembic
Publisher: Academic Press
ISBN: 0124200109
Category : Medical
Languages : en
Pages : 323

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Book Description
The Cytokines of the Immune System catalogs cytokines and links them to physiology and pathology, providing a welcome and hugely timely tool for scientists in all related fields. In cataloguing cytokines, it lists their potential for therapeutic use, links them to disease treatments needing further research and development, and shows their utility for learning about the immune system. This book offers a new approach in the study of cytokines by combining detailed guidebook-style cytokine description, disease linking, and presentation of immunologic roles. Supplies new ideas for basic and clinical research Provides cytokine descriptions in a guidebook-style, cataloging the origins, structures, functions, receptors, disease-linkage, and therapeutic potentials Offers a textbook-style view on the immune system with the immunologic role of each cytokine