Current Concepts of Intestinal Failure PDF Download

Author: Risto J. Rintala
Publisher: Springer
ISBN: 331942551X
Category : Medical
Languages : en
Pages : 164

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Book Description
This book provides readers with a succinct but comprehensive overview of current concepts relating to intestinal failure, including its treatment, with a particular focus on recent advancements. The opening chapters address basic aspects of intestinal failure, including etiology, clinical pathophysiology, physiology of intestinal adaptation, and intestinal microbiota. The complications of intestinal failure, such as bacterial overgrowth and intestinal failure-associated liver disease, are then discussed. A series of chapters specifically address important strategies in the nutritional, pharmacological, and surgical treatment of intestinal failure as well as the concept of intestinal rehabilitation. Finally, two significant emerging developments are considered: regenerative medicine and distraction enterogenesis. The authors are internationally recognized experts from Europe and North America who are ideally placed to describe current knowledge and progress in the field.

Author: Mandy L. Corrigan
Publisher: Academic Press
ISBN: 0128143312
Category : Technology & Engineering
Languages : en
Pages : 255

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Book Description
Adult Short Bowel Syndrome: Nutritional, Medical, and Surgical Management serves as a practical guide to the medical, surgical and nutritional care of complex patients with Short Bowel Syndrome (SBS), providing information on SBS with the most up-to-date, evidence-based data available. Additionally, the book presents global perspectives and highlights emerging areas of research that are influencing the care of patients with SBS. Intended for nutritionists, dieticians, physicians (specifically, general practitioners, gastroenterologists, and surgeons), nurse practitioners, pharmacists, students and researchers, this book serves as a quick reference on the medical, surgical and nutritional care of complex patients with short bowel syndrome. - Presents emerging areas of research related to Short Bowel Syndrome (gut microbiome, pre/probiotics), as well as current applications in clinical practice - Compiles an overview, classification and complications of the Short Bowel Syndrome disease state - Contains effective dietary concepts (including rationale and use of oral rehydration solutions) for managing malabsorption caused by Short Bowel Syndrome - Includes medical and pharmaceutical management techniques to compliment nutrition interventions - Discusses surgical options for consideration in patients with Short Bowel Syndrome - Highlights international perspectives on treatment and care

Author: Alan N. Langnas
Publisher: John Wiley & Sons
ISBN: 1405195797
Category : Medical
Languages : en
Pages : 416

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Book Description
Intestinal failure is a challenging, emerging field that has beenthe subject of much research and debate in recent years and hasonly recently become widely accepted as a distinct clinicalsyndrome. This comprehensive book provides an in-depth review ofscientific theory and clinical practice relating to intestinalfailure with specific emphasis on assessment and management as partof a multidisciplinary team. Compiled by an internationallyrecognised editorial team, the book provides a practical how-toguide to the management of adult and pediatric patients withintestinal failure, focusing on quality-of-life issues that are atthe heart of patient care. World experts from centers of excellence share their clinicalexperience and expertise, offering the first ever authoritativeresource on intestinal failure All aspects of patient management are covered, from diagnosisand medical and surgical management (including transplantation) tonutritional consideration and psychosocial aspects of care Numerous illustrations, flow diagrams and summary boxescomplement the text and emphasize important concepts, providing anaccessible approach to this complex field This landmark book is essential reading for anygastroenterologists, surgeons, transplant teams or clinicalnutritionists involved in the care of patients with intestinalfailure.

Author: Kimberly A. Davis
Publisher: Springer
ISBN: 149391121X
Category : Medical
Languages : en
Pages : 303

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Book Description
This volume is a comprehensive, state-of-the-art review for clinicians with an interest in the peri-operative nutritional management of all surgical patients. The text reviews normal physiology, the pathophysiology of starvation and surgical stressors, and focuses on appropriate nutritional repletion for various common disease states. Specifically, the text addresses the severe metabolic demands created by systemic inflammation, infection, and major insults such as trauma and burns. In addition, the book addresses the growing problem of obesity in surgical populations, including appropriate strategies directed towards the metabolic management of these patients. The text is designed for clinicians across levels of training and provides clear and concise evidence based guidelines for the metabolic management and nutritional support of the surgical patient. Written by experts in the field, Surgical Metabolism: The Metabolic Care of the Surgical Patient is a valuable resource for all clinicians involved in the care of the critically ill.

Author: Irving Taylor
Publisher: JP Medical Ltd
ISBN: 935152146X
Category : Medical
Languages : en
Pages : 240

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Book Description
Latest volume in the annually-publishing series that reviews current topics in general surgery and its major subspecialties. Contributions from recognised experts, the majority from throughout the UK, this new volume provides excellent revision material for professional examinations, and helps consultant surgeons keep up to date across the specialty.

Author: Christopher P. Duggan
Publisher: CRC Press
ISBN: 1439813914
Category : Medical
Languages : en
Pages : 564

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Book Description
A complex disease entity, intestinal failure (IF) has only recently become accepted as a distinct clinical syndrome. Improvements across a wide range of disciplines-including critical care and organ transplantation as well as surgical, medical, and nutritional therapies-have led to a steady rise in survival and quality of life for patients with IF.

Author: Godfrey Lule
Publisher: BoD – Books on Demand
ISBN: 9533079576
Category : Medical
Languages : en
Pages : 292

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Book Description
The 21st Century has seen a resurgence of research of the gastrointestinal tract, especially since it was established that it plays a central role as an immune system organ and consequentially has a huge impact on causation, impact and transmission of most human ailments. New diseases such as the Acquired Immunodeficiency Syndrome, hepatitis and tumours of the gastrointestinal tract have emerged and they are currently subjects of intensive research and topics of scientific papers published worldwide. Old diseases like diarrhea have become extremely complex to diagnose with new and old pathogens, drugs, tumours and malabsorptive disorders accounting for the confusion. This book has set out algorithms on how to approach such conditions in a systematic way both to reach a diagnosis and to make patient management cheaper and more efficient. "Current Concepts in Colonic Disorders" attempts to put all the new information into proper perspective with emphasis on aetiopathogenesis and providing rational approach to management of various old and new diseases. As the book editor, I have found this first edition extremely interesting and easy to understand. Comments on how to improve the content and manner of presentation for future editions are extremely welcome.

Author: Sushil K. Sarna
Publisher: Biota Publishing
ISBN: 1615041516
Category : Medical
Languages : en
Pages : 159

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Book Description
Three distinct types of contractions perform colonic motility functions. Rhythmic phasic contractions (RPCs) cause slow net distal propulsion with extensive mixing/turning over. Infrequently occurring giant migrating contractions (GMCs) produce mass movements. Tonic contractions aid RPCs in their motor function. The spatiotemporal patterns of these contractions differ markedly. The amplitude and distance of propagation of a GMC are several-fold larger than those of an RPC. The enteric neurons and smooth muscle cells are the core regulators of all three types of contractions. The regulation of contractions by these mechanisms is modifiable by extrinsic factors: CNS, autonomic neurons, hormones, inflammatory mediators, and stress mediators. Only the GMCs produce descending inhibition, which accommodates the large bolus being propelled without increasing muscle tone. The strong compression of the colon wall generates afferent signals that are below nociceptive threshold in healthy subjects. However, these signals become nociceptive; if the amplitudes of GMCs increase, afferent nerves become hypersensitive, or descending inhibition is impaired. The GMCs also provide the force for rapid propulsion of feces and descending inhibition to relax the internal anal sphincter during defecation. The dysregulation of GMCs is a major factor in colonic motility disorders: irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), and diverticular disease (DD). Frequent mass movements by GMCs cause diarrhea in diarrhea predominant IBS, IBD, and DD, while a decrease in the frequency of GMCs causes constipation. The GMCs generate the afferent signals for intermittent short-lived episodes of abdominal cramping in these disorders. Epigenetic dysregulation due to adverse events in early life is one of the major factors in generating the symptoms of IBS in adulthood.

Author: Arvind Venkat
Publisher: John Wiley & Sons
ISBN: 1119971586
Category : Medical
Languages : en
Pages : 306

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Book Description
With growing numbers of chronically ill patients surviving longer and receiving novel medical and surgical treatments, emergency departments are increasingly the venue for associated acute presentations. How can emergency physicians respond to these challenging and emerging conditions? This book focuses on the unusual and complex disease presentations not covered in detail in the standard textbooks, helping you manage patients with conditions such as congenital heart disease, cystic fibrosis, morbid obesity, intellectual disability and intestinal failure. Not only does this book provide guidance on evaluation and diagnosis, but it also addresses the practical issues of acute management and continuing referral. The individual chapters are written by high profile emergency physicians, in conjunction with appropriate specialists, and include authoritative evidence to back up the clinical information.

Author: Andreas Radbruch
Publisher: Springer Science & Business Media
ISBN: 3540297146
Category : Medical
Languages : en
Pages : 287

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Book Description
The immune system has been known to be capable of distinguishing self from non-self since the pioneering work of Paul Erhlich more than a century ago. Originally described in experiments studying blood transfusion comp- ibility, the principle of “horror autotoxicus” is still valid, although today the phenomenon is usually described in terms of tolerance or ignorance. A great deal has been learned about the various processes preventing self-reactivity normally. These include processes that operate during immune cell ontogeny and subsequently on reactivity of mature lymphocytes in the periphery. They encompass mechanisms that are intrinsic to potentially reactive lymphocytes and can result in central or peripheral deletion or the alteration of functional potential. In addition, there are in?uences that are extrinsic to potentially auto-reactive lymphocytes, including the function of regulatory cells, d- ferentiation state of antigen-presenting cells, availability of self-antigen, the cytokine and chemokine milieu, as well as the traf?cking patterns involved in generating productive immune interactions. It is clear that the immune system devotes a considerable effort to the avoidance of the development of potentially pathogenic self-reactivity. Despite this, the development of self-reactivity is relatively common. - though the development of autoimmune disease is less frequent, autoimmune diseases, such as rheumatoid arthritis, multiple sclerosis, systemic lupus e- thematosus, psoriasis, thyroiditis, and myasthenia gravis, are all too common, and can cause considerable morbidity and even mortality.