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Crystal-Induced Arthropathies. Gout and Pseudogout

Crystal-Induced Arthropathies. Gout and Pseudogout PDF Author: Patrick Kimuyu
Publisher: GRIN Verlag
ISBN: 3668623627
Category : Medical
Languages : en
Pages : 22

Book Description
Seminar paper from the year 2018 in the subject Medicine - Epidemiology, grade: 1, Egerton University, language: English, abstract: Gout and pseudogout are believed to the most prevalent crystal-induced arthropathies in humans. These disorders occur due to the deposition of crystals in the joints and soft tissues. This results into periarticular and articular inflammation and injury. Some of the most common crystals that are responsible for arthropathies such as gout and pseudogout include hydroxyapatite, monosodium urate (MSU), calcium oxalate and calcium pyrophosphate dehydrate (CPPD) (Rothschild, 2014). In practice, gout and pseudogout are relatively different despite the fact that they are crystal-induced arthropathies, and their difference can be explained by their definitions. Gout is defined as a crystal deposition disease that is characterized by the precipitation and super-saturation of monosodium urate (MSU) in tissues. This deposition of monosodium urate crystals causes inflammation of the joints and soft tissues, and this is attributable to tissue damage. Therefore, gout is characterized by sub-acute or acute attacks of joints or the inflammation of soft tissues resulting from the deposition of monosodium urate. The clinical course of gout involves an underlying metabolic aberrancy referred to as hyperuricemia which is defined as the serum urate level of more than 6.8 mg/dL (Al-Ashkar, 2010). On the other hand, pseudogout is defined as a clinical syndrome that resembles gout, and it is caused by the deposition of calcium pyrophosphate dehydrate crystals in soft tissues and joints, resulting into the inflammation and cartilage tissue damage. Therefore, the term pseudogout emanates from the nature of its clinical presentation in which acute attacks of the joints resembles those observed in gout (Al-Ashkar, 2010). However, it is worth noting that, in pseudogout, chondrocalcinosis is the most distinctive feature for the syndrome although some patients with chondrocalcinosis do not present with pseudogout. This seminar paper focuses on gout and pseudogout.

Crystal-Induced Arthropathies. Gout and Pseudogout

Crystal-Induced Arthropathies. Gout and Pseudogout PDF Author: Patrick Kimuyu
Publisher: GRIN Verlag
ISBN: 3668623627
Category : Medical
Languages : en
Pages : 22

Book Description
Seminar paper from the year 2018 in the subject Medicine - Epidemiology, grade: 1, Egerton University, language: English, abstract: Gout and pseudogout are believed to the most prevalent crystal-induced arthropathies in humans. These disorders occur due to the deposition of crystals in the joints and soft tissues. This results into periarticular and articular inflammation and injury. Some of the most common crystals that are responsible for arthropathies such as gout and pseudogout include hydroxyapatite, monosodium urate (MSU), calcium oxalate and calcium pyrophosphate dehydrate (CPPD) (Rothschild, 2014). In practice, gout and pseudogout are relatively different despite the fact that they are crystal-induced arthropathies, and their difference can be explained by their definitions. Gout is defined as a crystal deposition disease that is characterized by the precipitation and super-saturation of monosodium urate (MSU) in tissues. This deposition of monosodium urate crystals causes inflammation of the joints and soft tissues, and this is attributable to tissue damage. Therefore, gout is characterized by sub-acute or acute attacks of joints or the inflammation of soft tissues resulting from the deposition of monosodium urate. The clinical course of gout involves an underlying metabolic aberrancy referred to as hyperuricemia which is defined as the serum urate level of more than 6.8 mg/dL (Al-Ashkar, 2010). On the other hand, pseudogout is defined as a clinical syndrome that resembles gout, and it is caused by the deposition of calcium pyrophosphate dehydrate crystals in soft tissues and joints, resulting into the inflammation and cartilage tissue damage. Therefore, the term pseudogout emanates from the nature of its clinical presentation in which acute attacks of the joints resembles those observed in gout (Al-Ashkar, 2010). However, it is worth noting that, in pseudogout, chondrocalcinosis is the most distinctive feature for the syndrome although some patients with chondrocalcinosis do not present with pseudogout. This seminar paper focuses on gout and pseudogout.

Gout and Other Crystal Arthropathies

Gout and Other Crystal Arthropathies PDF Author: Robert Terkeltaub
Publisher: Elsevier Health Sciences
ISBN: 1437728642
Category : Medical
Languages : en
Pages : 374

Book Description
Gout and Other Crystal Arthropathies, by Dr. Robert Terkeltaub, presents the state-of-the-art, clinically-focused coverage you need to manage these increasingly prevalent diseases. Diagnose the full range of crystal arthropathies-including pseudogout, intercritical gout, hyperuricemia, and gouty arthritis-and treat your patients effectively with discussions of recently-approved drugs like Uloric and those currently under review, such as Kristexxa and Colcryst. With coverage of the latest therapies, preventions, and imaging studies, along with access to the fully searchable text online at www.expertconsult.com, this comprehensive resource is ideal for any physician who diagnoses, treats, and manages gout and crystal-induced arthropathies. Access the fully searchable contents online at www.expertconsult.com. Stay current on recent developments such as uricosuric therapy and inhibitor therapy; gout flare prophylaxis and colchicines; ultrasound in the diagnosis of crystal deposition diseases; imaging of gout, CPPD, and hydroxyapatitie deposition diseases; and uricase therapy of gout. Manage the full range of crystal arthropathies with 25 clinically-focused chapters on pseudogout, intercritical gout, hyperuricemia, gouty arthritis, and more. Treat your patients effectively using the latest information on drug treatments, from the recently-approved Uloric to Kristexx and Colcryst, which are still under review. The tools to you need to diagnose, treat, and manage gout and other crystal arthropathies

Crystal-Induced Arthropathies

Crystal-Induced Arthropathies PDF Author: Robert L. Wortmann
Publisher: CRC Press
ISBN: 9780849393822
Category : Medical
Languages : en
Pages : 0

Book Description
Divided into five expansive sections, this guide provides an in-depth review of crystal-induced arthritis and related disorders. Providing a historical perspective throughout, this work includes detailed descriptions of the clinical features of these diseases, as well as a current overview of their identification, epidemiology, genetics, and underlying pathophysiology. This authoritative guide also reviews case studies, current diagnostic tools, and the prevalence of these conditions while introducing new and emerging therapies for disease management.

Orthopedic Surgery Clerkship

Orthopedic Surgery Clerkship PDF Author: Adam E. M. Eltorai
Publisher: Springer
ISBN: 3319525670
Category : Medical
Languages : en
Pages : 753

Book Description
This quick-reference guide is the first book written specifically for the many third- and fourth-year medical students rotating on an orthopedic surgery service. Organized anatomically, it focuses on the diagnosis and management of the most common pathologic entities. Each chapter covers history, physical examination, imaging, and common diagnoses. For each diagnosis, the book sets out the typical presentation, options for non-operative and operative management, and expected outcomes. Chapters include key illustrations, quick-reference charts, tables, diagrams, and bulleted lists. Each chapter is co-authored by a senior resident or fellow and an established academic physician and is concise enough to be read in two or three hours. Students can read the text from cover to cover to gain a general foundation of knowledge that can be built upon when they begin their rotation, then use specific chapters to review a sub-specialty before starting a new rotation or seeing a patient with a sub-specialty attending. Practical and user-friendly, Orthopedic Surgery Clerkship is the ideal, on-the-spot resource for medical students and practitioners seeking fast facts on diagnosis and management. Its bullet-pointed outline format makes it a perfect quick-reference, and its content breadth covers the most commonly encountered orthopedic problems in practice.

Rheumatology for Primary Care Providers

Rheumatology for Primary Care Providers PDF Author: Yousaf Ali
Publisher: Springer Nature
ISBN: 3030806995
Category : Medical
Languages : en
Pages : 421

Book Description
Current texts in rheumatology are very detailed and designed specifically for rheumatologists. This clear and concise guide is targeted at the busy clinician who comes into contact with both common and uncommon rheumatologic disorders. Many chapters presents a common clinical scenario and include a definition of the disease while outlining incidence and prevalence, common manifestations, treatment and pitfalls. A range of topics are included in the fifteen chapters including osteoarthritis, rheumatoid arthritis, fibromyalgia, metabolic bone disease, gout and scleroderma, among others. Written by experts in the field, Rheumatology for Primary Care Providers is a definitive guide to rheumatology for the primary care physician and non-specialist.

Diagnosis and Treatment in Internal Medicine

Diagnosis and Treatment in Internal Medicine PDF Author: Patrick Davey
Publisher: Oxford University Press
ISBN: 019956874X
Category : Medical
Languages : en
Pages : 1297

Book Description
Diagnosis and Treatment in Internal Medicine equips trainee doctors with the essential skills and core knowledge to establish a diagnosis reliably and quickly, before outlining the management of the clinical condition diagnosed. Organised into three sections, the first provides a vital overview, whilst the second focuses on common presentations and diagnoses. Uniquely, this new book shows readers how to turn symptoms into a list of diagnoses ordered by probability - a differential diagnosis. Experienced consultants who teach trainees every day demonstrate how to derive an ordered differential diagnosis, how to narrow this down to a single diagnosis and if not, how to live with diagnostic uncertainty. The final section provides a comprehensive account of the management of system-based syndromes and diseases. Highly-structured chapters emphasize how common conditions present, how to approach a diagnosis, and how to estimate prognosis, treatment and its effectiveness. An onus is placed on the development of crucial diagnostic skills and the ability to devise evidence-based management plans quickly and accurately, making this an ideal text for core medical trainees.

Acute Medicine

Acute Medicine PDF Author: David C. Sprigings
Publisher: John Wiley and Sons
ISBN: 1444327259
Category : Medical
Languages : en
Pages : 632

Book Description
This extremely popular title has become the definitive pocket guide to the management of medical emergencies for front-line hospital doctors. It provides detailed guidance on the diagnosis and treatment of all common conditions and includes a step-by-step guide to the nine most important practical procedures in acute medicine.

Prosthetic Joint Infections

Prosthetic Joint Infections PDF Author: Trisha Peel
Publisher: Springer
ISBN: 3319652508
Category : Medical
Languages : en
Pages : 270

Book Description
This book outlines the most updated clinical guidelines that are vital for the prevention infections and care of patients with joint infections following a replacement surgery, one of the highest volume medical interventions globally. Sections address the diagnosis, management approaches and prevention of prosthetic joint infections. Written by experts in the field, this text provides a brief overview of the literature and current recommendations in each of the specified areas. Given the rapidly evolving state-of-play in this clinical area, this compendium grows increasingly important to clinicians in their management decisions. Prosthetic Joint Infections is a valuable resource for infectious disease specialists, epidemiologists, surgeons, and orthopedic specialists who may work with patients with prosthetic joint infections.

Mayo Clinic on Arthritis

Mayo Clinic on Arthritis PDF Author: Gene G. Hunder
Publisher:
ISBN:
Category : Family & Relationships
Languages : en
Pages : 208

Book Description
Covers the causes and symptoms of arthritis; offers tips on pain control, diet, and exercise; and describes such treatment options as medications, surgical procedures, and alternative therapies.

Clinical Foundations of Musculoskeletal Medicine

Clinical Foundations of Musculoskeletal Medicine PDF Author: Robert J. Esther
Publisher: Springer Nature
ISBN: 303042894X
Category : Medical
Languages : en
Pages : 421

Book Description
Musculoskeletal (MSK) disorders have a high prevalence and are one of the main reasons for patients to consult with a provider. For a range of issues from injury to back pain to rheumatic disease, musculoskeletal pathology is the second most common reason for a patient to see a primary care provider. However, despite their prevalence and significant socioeconomic impact, musculoskeletal disorders are relatively undertaught in medical schools in the United States. While all medical, nursing and physician assistant students receive exposure to some MSK content, in many medical schools this material does not receive curricular exposure commensurate with its prevalence. This practical textbook fills in that gap. All aspects of musculoskeletal disease and its management are presented concisely for quick reference and review, with each chapter opening with clear goals and objectives. The text begins with a discussion of the anatomy and physiology of bone, cartilage and muscle, including imaging techniques and interpretation. Musculoskeletal infections, tumors and vascular conditions are then covered, along with common rheumatic conditions such as rheumatoid and osteoarthritis, metabolic bone disease, and age-specific and traumatic conditions. Finally, the upper and lower extremity and spine are thoroughly discussed in terms of anatomy/pathoanatomy, common clinical conditions, physical exam, and common radiographic and clinical correlations. The main audience for Clinical Foundations of Musculoskeletal Medicine is medical students seeking to improve their understanding of common musculoskeletal conditions. Given the relevance of musculoskeletal conditions to a range of providers, this book can also be used for the musculoskeletal education of allied professionals such as physician assistants (PA) and nurse practitioner students. It could likewise serve as a resource for practicing medical professionals to develop and enhance their knowledge in this content area.