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Author: Philippa H. Francis-West Publisher: Springer Science & Business Media ISBN: 3642555705 Category : Science Languages : en Pages : 217
Book Description
Craniofacial development is a multistep and intricate process initially involving a number of inductive interactions that control neural and neural crest development, which are followed by a series of epithelial-mesenchymal interactions that control outgrowth, patterning, and skeletal differentiation. Certain aspects of craniofacial development are unique developmental processes in higher vertebrates. First, in higher vertebrates the cranial neural crest, in contrast to the trunk neural crest, gives rise to the skeletal structures. These skeletal elements include those comprising mem brane bone and secondary cartilage, which with the exception of the clavicle are tissue types found exclusively in the head in higher vertebrates. Second, with the exception of the tongue, the origin of the musculature is distinct from other regions of the body. The body and tongue muscles are formed from the segmented epithelial somites whilst the head musculature is formed from unsegmented paraxial and prechordal mesoderm. Furthermore, the signalling cascades that control myogenic differentia tion appear to be distinct as determined by gene expression and the response of myogenic cells to growth factors. Finally, the neurogenic placodes, which give rise to the sensory organs and some cranial ganglia, are only found in the head. Over recent years, there have been significant advances in our knowledge of the molecular proc esses that control craniofacial development in a number of animal models. This has given insight into the genes that control many aspects of head development from the initial induction of the head to the final stages of differentiation.
Author: Philippa H. Francis-West Publisher: Springer Science & Business Media ISBN: 3642555705 Category : Science Languages : en Pages : 217
Book Description
Craniofacial development is a multistep and intricate process initially involving a number of inductive interactions that control neural and neural crest development, which are followed by a series of epithelial-mesenchymal interactions that control outgrowth, patterning, and skeletal differentiation. Certain aspects of craniofacial development are unique developmental processes in higher vertebrates. First, in higher vertebrates the cranial neural crest, in contrast to the trunk neural crest, gives rise to the skeletal structures. These skeletal elements include those comprising mem brane bone and secondary cartilage, which with the exception of the clavicle are tissue types found exclusively in the head in higher vertebrates. Second, with the exception of the tongue, the origin of the musculature is distinct from other regions of the body. The body and tongue muscles are formed from the segmented epithelial somites whilst the head musculature is formed from unsegmented paraxial and prechordal mesoderm. Furthermore, the signalling cascades that control myogenic differentia tion appear to be distinct as determined by gene expression and the response of myogenic cells to growth factors. Finally, the neurogenic placodes, which give rise to the sensory organs and some cranial ganglia, are only found in the head. Over recent years, there have been significant advances in our knowledge of the molecular proc esses that control craniofacial development in a number of animal models. This has given insight into the genes that control many aspects of head development from the initial induction of the head to the final stages of differentiation.
Author: Sebastian Dworkin Publisher: Humana ISBN: 9781071618493 Category : Science Languages : en Pages : 0
Book Description
This volume explores scientific methodologies currently employed to integrate observational developmental biology, tissue explant and cell-based approaches and genetic/molecular technologies to develop a holistic understanding of craniofacial development. Chapters guide readers through the use of disparate models to study formation of the head and face (c. elegans, zebrafish, mouse, alongside human imaging approaches), together with cell culture, tissue explant and in vivo cell imaging and analysis techniques. At the molecular level, chapters include analysing gene expression using in-situ hybridisation and single-cell RNA-Sequencing (scRNA-SEQ), as well as genetic modification techniques such as CRISPR/Cas9-mediated deletion. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Craniofacial Development: Methods and Protocols aims to be a guide in the field of craniofacial development for senior and new researchers looking to expand their existing research programs to encompass novel techniques.
Author: Geoffrey H. Sperber, Geoffrey D. Guttmann, Steven M. Sperber Publisher: PMPH-USA ISBN: 9781550091274 Category : Embryology, Human Languages : en Pages : 236
Book Description
The accompanying CD-ROM includes the complete text and illustrations from the print volume, as well as three-dimensional movies that show reconstructions of embryos.
Author: George T.J. Huang Publisher: John Wiley & Sons ISBN: 1118279239 Category : Science Languages : en Pages : 578
Book Description
Stem Cells, Craniofacial Development and Regeneration is an introduction to stem cells with an emphasis on their role in craniofacial development. Divided into five sections, chapters build from basic introductory information on the definition and characteristics of stem cells to more indepth explorations of their role in craniofacial development. Section I covers embryonic and adult stem cells with a focus on the craniofacial region, while sections II-IV cover the development and regeneration of craniofacial bone, tooth, temporomandibular joint, salivary glands and muscle. Concluding chapters describe the current, cutting-edge research utilizing stem cells for craniofacial tissue bioengineering to treat lost or damaged tissue. The authoritative resource for dentistry students as well as craniofacial researchers at the graduate and post-graduate level, Stem Cells, Craniofacial Development and Regeneration explores the rapidly expanding field of stem cells and regeneration from the perspective of the dentistry and craniofacial community, and points the way forward in areas of tissue bioengineering and craniofacial stem cell therapies.
Author: Publisher: Academic Press ISBN: 0124166113 Category : Science Languages : en Pages : 754
Book Description
Craniofacial Development, the latest volume of Current Topics in Developmental Biology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods in Craniofacial Development, and includes sections on such topics as microRNAs in craniofacial development and epigenetic regulation in craniofacial development. Provides a comprehensive book on craniofacial development and tissue regeneration Authored by leading experts in this field Carefully organized to cover an array of topics critical in helping readers learn the most important aspects of craniofacial development and tissue regeneration
Author: David P. Rice Publisher: Karger Medical and Scientific Publishers ISBN: 3805583265 Category : Medical Languages : en Pages : 249
Book Description
"In this volume craniofacial developmental and evolutionary biologists, oral and maxillofacial surgeons, orthodontists as well as pediatric and plastic surgeons will find a wealth of recent information on the field of craniofacial development, deformity and its treatment."--BOOK JACKET.
Author: Geoffrey H. Sperber Publisher: PMPH-USA ISBN: 9781607950325 Category : Developmental genetics Languages : en Pages : 264
Book Description
Provides clinicians with a basic background for treating craniofacial anomalies. Includes a CD-ROM with entire text and illustrations of the book in fully searchable PDF files Accompanying CD also contains three-dimensional movies that show reconstructions of embryos
Author: J Timothy Wright Publisher: Springer ISBN: 3319130579 Category : Medical Languages : en Pages : 131
Book Description
This book provides the practitioner with a framework for establishing a diagnosis and developing a suitable treatment plan in patients presenting with a range of developmental defects of the teeth. The conditions covered include failure of tooth eruption, hypodontia, premature tooth exfoliation, defects of enamel development, and defects of dentin development, with full consideration of both syndromic and non-syndromic defects. In each case the phenotype and genotype are first described, followed by diagnostic information, including the availability of genetic testing, and treatment options. Summarizing tables are used to highlight the key diagnostic features, and helpful illustrated case presentations are included. Cleft palate is also addressed, with details on etiology, phenotypes, treatment timing and approaches, and dental management. The closing chapter provides stimulating reflections on potential future directions in the diagnosis and treatment of these disorders.
Author: Geoffrey H. Sperber Publisher: Pmph USA Limited ISBN: 9781607952824 Category : Facial bones Languages : en Pages : 276
Book Description
The field of embryology has experienced a period of explosive growth since the previous edition of this book was published nearly a decade ago. The insights of genetic expression in determining the unfolding of the embryonic layers have revolutionised our understanding of some of the mechanisms of embryogenesis. As implied by the title of the new edition, Craniofacial Embryogenetics and Development, genetics is linked with embryology in this text. Virtually all embryological development has an underlying genetic component, and the basic science of genetics is the key in uncovering the many mysteries of embryogenesis. The tools of molecular genetics have provided insights into developmental mechanisms that allow us the ability to identify transient regions of genetic expression patterns. Unraveling the precise biochemical and mechanical interactions of discrete regions in the unfolding embryonic components remains a dauntingly-complex challenge to understanding the conversion of the genome into the phenome. The addition of genetic information gleaned from other mammalian species might aid in dissecting human embryology into comprehensible components to understand normal and abnormal development. This new edition is dedicated to this objective and will prove invaluable to plastic and orofacial surgeons, otolaryngologists, orthodontists, neonatal pediatricians, speech pathologists, teratologists, embryologists, and anatomists. Key Features: Provides clinicians with a basic background for assessing and treating craniofacial anomalies. Describes recent technical advances in optical projection tomography, photoacoustic and 3D imaging, small-angle X-ray scattered (SAXS) tomography and morphometrics and their impact on embryogenetics.
Author: Philippa H. Francis-West
Author: Philippa H. Francis-West
Author: Sebastian Dworkin
Author: Erika Kuchler
Author: Geoffrey H. Sperber, Geoffrey D. Guttmann, Steven M. Sperber
Author: George T.J. Huang
Author: 
Author: David P. Rice
Author: Geoffrey H. Sperber
Author: J Timothy Wright
Author: Geoffrey H. Sperber