Contribution de l'hyperglycémie au risque cardiovasculaire des diabétiques de type 2 PDF Download

Author: Florence Poggi-Travert
Publisher:
ISBN:
Category :
Languages : fr
Pages : 324

View

Book Description
Il s’agit de travaux de Recherche Clinique sur la thématique « Une intervention chez des diabétiques de type 2 entraînant le retour à une glycémie normale permet elle le retour à un risque cardiovasculaire proche de celui de la population générale ? ». Le travail présenté, réalisé de 2004 à 2007 sous la direction du Pr Marre, en collaboration avec l’ Université de Sydney contribue à y répondre. L’essai ADVANCE auquel j’ai participé, portait sur 11000 patients diabétiques de type 2 et comparait l’effet d’une intensification du traitement hypoglycémiant sur le risque de développer ou d’aggraver une complication micro/macrovasculaire du diabète. Cette étude a été menée à son terme, nous avons obtenu des résultats interprétables et les avons publiés dans une revue importante : Intensive Blood Glucose Control and Vascular Outcomes in Patients with Type 2 Diabetes - N Engl J Med. 2008 Jun 12; 358(24):2560-2572. Le contexte, le protocole, les aspects stratégiques et opérationnels, les résultats, et les discussions qui s’y rattachent sont développés dans cette thèse. Un programme d’analyses et de protocoles à suivre est également introduit.

Author: Robert Haïat
Publisher:
ISBN: 9782876715127
Category :
Languages : fr
Pages : 93

View

Book Description
Tous les cliniciens savent combien il est essentiel d'avoir des repères au moment de fixer une prescription qui engage l'avenir du patient. Tel est l'objectif de cet aide-mémoire qui contient les clefs thérapeutiques essentielles du diabète de type 2 et de ses complications, telles qu'elles ressortent des grands essais cliniques et des recommandations publiés dans la littérature médicale. La Collection Opus propose une approche actualisée et didactique des grands thèmes de santé publique dont la synthèse représente la base indispensable à toute pratique médicale.

Author: Anne-Sophie Boutillier
Publisher:
ISBN:
Category :
Languages : fr
Pages : 210

View

Book Description
Le diabète de type 2 représente la forme la plus répandue du diabète. Sur le plan mondial, le diabète de type 2 touche environ 2,5 % de la population adulte. En France, le diabète de type 2 concerne environ 1,7 millions d’individus, 10 % de la population au-delà de 60 ans et 15 % après 70 ans. L’absence de symptômes cliniques au début de la maladie en fait une pathologie souvent tardivement diagnostiquée, après l’installation des complications. Ces dernières se manifestent sous forme de pathologies métaboliques ou vasculaires, les plus graves étant les atteintes cardiovasculaires. Le traitement du diabète de type 2 vise ainsi un double objectif : maintenir l’équilibre glycémique et lutter contre les facteurs de risque vasculaire, jouant un rôle déterminant dans la constitution de la macro-angiopathie. La prise en compte du risque cardiovasculaire du diabétique, occupant une place de plus en plus importante dans la stratégie thérapeutique, dépasse maintenant la simple utilisation d’antidiabétiques oraux. De nombreuses études cliniques, concernant les antidiabétiques oraux et les statines, permettent d’affirmer qu’une approche agressive vis-à-vis de tous les facteurs de risque permet de réduire significativement la survenue des complications cardiovasculaires. De tels résultats pourraient conduire, dans l’avenir, à considérer le diabète de type 2 comme une pathologie cardiovasculaire à part entière.

Author:
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 128

View

Book Description

Author: Makoto Nagano
Publisher: New York : Raven Press
ISBN:
Category : Medical
Languages : en
Pages : 568

View

Book Description

Author: Peter Barnes
Publisher: CRC Press
ISBN: 9781853176425
Category : Medical
Languages : en
Pages : 164

View

Book Description
This text gives a comprehensive discussion of the range of treatments available in asthma therapy and aims to provide a reference manual for both the specialist and trainee in respiratory medicine.

Author: Katherine Renpenning, MScN
Publisher: Springer Publishing Company
ISBN: 0826107796
Category : Medical
Languages : en
Pages : 253

View

Book Description
"This is an excellent review of the development of self-care deficit theory and the use of self-care in nursing practice. Explanations of the various theories and theory terms are well done and written at a level that novice theorists can relate to. The authors demonstrate how self-care science can be fiscally and effectively applied to the care of patients/clients."--Doody's Medical Reviews Dorothea Orem's Self-Care Theory has been used as a foundation for nursing practice in healthcare institutions and as the basis of curricula in nursing schools for decades. This book explores the high-level theory of the application of Orem's Self-Care Theory, and how it can improve patient outcomes as well as cost-effectiveness of nursing care delivery. Written for nursing theorists, researchers, administrators, and graduate students, the text addresses the relationship of self-care theory and evidence-based care in nursing, and provides a solution to improving contemporary healthcare outcomes. The book is divided into three sections. Section one discusses the reason for the existence of the nursing profession, and identifies the performance of self-care. Section two covers three nursing practice sciences-wholly compensatory nursing, partly compensatory nursing, and supportive educative nursing. Section three offer suggestions on how health care organizations can incorporate this broadened perspective of what constitutes evidence based practice and on-going research methodology into every-day delivery of nursing services. Key Features: Includes case examples to illustrate the application of theory to nursing practice Provides a current, cost-effective resource for implementing Orem's Self-Care Deficit Theory for effective evidence-based practice Builds the link between the application of Orem's Self Care Theory and improved patient and fiscal healthcare outcomes

Author: Derek LeRoith
Publisher: Lippincott Williams & Wilkins
ISBN: 9780781740975
Category : Medical
Languages : es
Pages : 1606

View

Book Description
Thoroughly revised and updated, this Third Edition encompasses the most recent advances in molecular and cellular research and describes the newest therapeutic modalities for type 1 and type 2 diabetes mellitus. Chapters by leading experts integrate the latest basic science and clinical research on diabetes mellitus and its complications. The text is divided into ten major sections, including extensive sections on therapeutics, diabetes during pregnancy, and complications. New chapters cover stem cell therapy for type 1 diabetes; genetics and treatment of obesity; new therapies to promote insulin action; vasculopathy; islet cell protocols; triglycerides in muscle; hypoglycemia in the adult; and the Diabetes Prevention Program.

Author: Dr Malcolm Kendrick
Publisher: Kings Road Publishing
ISBN: 1843582368
Category : Health & Fitness
Languages : en
Pages : 337

View

Book Description
Statins are widely prescribed to lower blood cholesterol levels and claim to offer unparalleled protection against heart disease. Believed to be completely safe and capable of preventing a whole series of other conditions, they are the most profitable drug in the history of medicine. In this groundbreaking book, GP Malcolm Kendrick exposes the truth behind the hype. He will change the way we think about cholesterol forever. Rubbishing the diet-heart hypothesis, in which clinical trials 'prove' that high cholesterol causes heart disease and a high-fat diet leads to heart disease, Kendrick lambastes a powerful pharmaceutical industry and unquestioning medical profession, who, he claims, perpetuate the madcap concepts of 'good' and 'bad' cholesterol and cholesterol levels to convince millions of people to unnecessarily spend billions of pounds on statins. Clearly and comprehensively debunking assumptions on what constitute a healthy lifestyle and diet, "The Great Cholesterol Con" is the accessible, indispensable and absorbing case against statins and for a more common-sense approach to heart disease and general wellbeing. No more over-hyped miracle drugs; no more garlic, red wine, anti-oxidants, fruit or vegetables; even a vegetarian diet is rejected in this controversial yet authoritative critique of how we have been mislead over how food and drugs affect our coronary health. Here, for the first time, is the invaluable guide for anyone who though there was a miracle cure for heart disease, "The Great Cholesterol Con" is a fascinating breakthrough that will set dynamite under the whole area.

Author: Norman Sharpe
Publisher: CRC Press
ISBN: 9781853178672
Category : Medical
Languages : en
Pages : 288

View

Book Description
The 19 chapters which comprise this text cover all aspects of heart failure, and are extremely readable and well-organized. The references selected for each chapter are highly sufficient and there is excellent coverage of all the pharmaceutical treatments, which have proven effective in the management of heart failure; moreover, there are chapters on the non-pharmacological management as well. The book instructs the physician in how to use the newer drugs, either singly or in combination and the clinical trials chapter gives the reader a balanced view of what is happening in research.