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Author: Sandra Knowles Weller Publisher: Caister Academic Press Limited ISBN: 9781904455769 Category : Science Languages : en Pages : 0
Book Description
Alphaherpesviruses are a fascinating group of DNA viruses that includes important human pathogens such as herpes simplex virus type 1 (HSV-1), HSV-2, and varicella-zoster virus (VZV): the causative agents of cold sores, genital ulcerous disease, and chickenpox/shingles, respectively. A key attribute of these viruses is their ability to establish lifelong latent infection in the peripheral nervous system of the host. Such persistence requires subversion of the host's immune system and intrinsic antiviral defense mechanisms. Understanding the mechanisms of the immune evasion and what triggers viral reactivation is a major challenge for today's researchers. This has prompted enormous research efforts into understanding the molecular and cellular biology of these viruses. This up-to-date and comprehensive volume aims to distill the most important research in this area providing a timely overview of the field. Topics covered include: transcriptional regulation, DNA replication, translational control, virus entry and capsid assembly, the role of microRNAs in infection and oncolytic vectors for cancer therapy. In addition there is coverage of virus-host interactions, including apoptosis, subversion of host protein quality control and DNA damage response pathways, autophagy, establishment and reactivation from latency, interferon responses, immunity and vaccine development. Essential reading for everyone working with alphaherpesviruses and of interest to all virologists working on latent infections.
Author: Sandra Knowles Weller Publisher: Caister Academic Press Limited ISBN: 9781904455769 Category : Science Languages : en Pages : 0
Book Description
Alphaherpesviruses are a fascinating group of DNA viruses that includes important human pathogens such as herpes simplex virus type 1 (HSV-1), HSV-2, and varicella-zoster virus (VZV): the causative agents of cold sores, genital ulcerous disease, and chickenpox/shingles, respectively. A key attribute of these viruses is their ability to establish lifelong latent infection in the peripheral nervous system of the host. Such persistence requires subversion of the host's immune system and intrinsic antiviral defense mechanisms. Understanding the mechanisms of the immune evasion and what triggers viral reactivation is a major challenge for today's researchers. This has prompted enormous research efforts into understanding the molecular and cellular biology of these viruses. This up-to-date and comprehensive volume aims to distill the most important research in this area providing a timely overview of the field. Topics covered include: transcriptional regulation, DNA replication, translational control, virus entry and capsid assembly, the role of microRNAs in infection and oncolytic vectors for cancer therapy. In addition there is coverage of virus-host interactions, including apoptosis, subversion of host protein quality control and DNA damage response pathways, autophagy, establishment and reactivation from latency, interferon responses, immunity and vaccine development. Essential reading for everyone working with alphaherpesviruses and of interest to all virologists working on latent infections.
Author: Publisher: ISBN: Category : Medicine Languages : en Pages : 836
Book Description
Includes section, "Recent book acquisitions" (varies: Recent United States publications) formerly published separately by the U.S. Army Medical Library.
Author: David Ward Publisher: Fairleigh Dickinson Univ Press ISBN: 9780838636763 Category : History Languages : en Pages : 260
Book Description
This book is an in-depth analysis of three of the most crucial years in twentieth-century Italian history, the years 1943-46. After more than two decades of a Fascist regime and a disastrous war experience during which Italy changed sides, these years saw the laying of the political and cultural foundations for what has since become known as Italy's First Republic. Drawing on texts from the literature, film, journalism, and political debate of the period, Antifascisms offers a thorough survey of the personalities and positions that informed the decisions taken in this crucial phase of modern Italian history.
Author: Publisher: Chronicle Books ISBN: 1452181896 Category : Humor Languages : en Pages : 114
Book Description
Featuring 30 types of breasts, The Boob Book is an illustrated celebration of womanhood and the boobs that come with it. Scattered throughout are boob miscellany: a boob personality flow chart, boob facts, boob self-care tips, a roundup of bras, types of nipples, a boob doodle, and illustrated ways we show off the goods. This joyful book features breasts of all colors and sizes—from "The Handful" to "The Mom-To-Be" to "The Small but Mighty"—showing women that every boob type is weird, beautiful, and natural. • An illustrated love letter to a girl's breast friend • Filled with fun and interactive boob-related miscellany, like a boob personality test (are you a "Chillaxer" or a "Handful"?), boob facts, and breast self-care tips • Light, celebratory, and a little cheeky—but ultimately sincere Let's hear it for our bosom buddies. Our mammary mamas. Our breasts-in-arms. From small and mighty to large and in charge to long, short, hairy, bumpy, or any boobs in between, this book uplifts them all. • A perfect book for women of all generations—from friends to mothers and daughters—or anyone who wants to send some extra support and love to their ladies • Ideal for anyone who needs a boob-size boost • Great for those who enjoyed Feminist Activity Book by Gemma Correll, Celebrating You: (And the Beautiful Person You Are) by M. H. Clark, and Gross Anatomy: Dispatches from the Front (and Back) by Mara Altman
Author: Sandra Knowles Weller
Author: Sandra Knowles Weller
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Author: David Ward
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