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Genetic Disorders Among Arab Populations

Genetic Disorders Among Arab Populations PDF Author: Ahmad S. Teebi
Publisher:
ISBN: 9780195093056
Category : Medical
Languages : en
Pages : 538

Book Description
Few regions of the world have a more varied physiography or a richer ethnic, religious, social, and cultural mix than the Arab world. As a consequence, Arabs are genetically diverse despite their linguistic and religious cohesion. High but variable rates of inbreeding prevail in all Arab countries with numerous examples of isolates among them. These include some Bedouin groups, Nubians, Druze, Jews, and others. Arab populations have high frequencies of autosomal recessive disorders, homozygosity of autosomal dominant and X-linked traits, and a wealth of new syndromes and variants, the majority of which are autosomal recessive. Genetic disorders that cause major health problems include hemoglobinopathies, neurogenetic disorders, inherited metabolic diseases, and inborn error of morphogenesis. Because of their characteristically high prevalence, some of these disorders are considered markers for Arab populations. This book presents the unique profile of genetic disorders and variants in Arabs. In addition, it describes their unusual demographic pattern including fertility rates and other population dimensions, family structure, magnitude and effects of consanguineous marriages and indicators of health and disease. Genetic counseling and the distinctive cultural and religious attitudes towards various genetic issues are also presented. Disorders that have increased tribal occurrences or are limited to large kindreds, as well as small geographic or religious isolates, are highlighted to facilitate their recognition, study, and management.

Genetic Disorders Among Arab Populations

Genetic Disorders Among Arab Populations PDF Author: Ahmad S. Teebi
Publisher:
ISBN: 9780195093056
Category : Medical
Languages : en
Pages : 538

Book Description
Few regions of the world have a more varied physiography or a richer ethnic, religious, social, and cultural mix than the Arab world. As a consequence, Arabs are genetically diverse despite their linguistic and religious cohesion. High but variable rates of inbreeding prevail in all Arab countries with numerous examples of isolates among them. These include some Bedouin groups, Nubians, Druze, Jews, and others. Arab populations have high frequencies of autosomal recessive disorders, homozygosity of autosomal dominant and X-linked traits, and a wealth of new syndromes and variants, the majority of which are autosomal recessive. Genetic disorders that cause major health problems include hemoglobinopathies, neurogenetic disorders, inherited metabolic diseases, and inborn error of morphogenesis. Because of their characteristically high prevalence, some of these disorders are considered markers for Arab populations. This book presents the unique profile of genetic disorders and variants in Arabs. In addition, it describes their unusual demographic pattern including fertility rates and other population dimensions, family structure, magnitude and effects of consanguineous marriages and indicators of health and disease. Genetic counseling and the distinctive cultural and religious attitudes towards various genetic issues are also presented. Disorders that have increased tribal occurrences or are limited to large kindreds, as well as small geographic or religious isolates, are highlighted to facilitate their recognition, study, and management.

Consanguinity in Context

Consanguinity in Context PDF Author: Alan H. Bittles
Publisher: Cambridge University Press
ISBN: 1107376939
Category : Science
Languages : en
Pages : 325

Book Description
An essential guide to this major contemporary issue, Consanguinity in Context is a uniquely comprehensive account of intra-familial marriage. Detailed information on past and present religious, social and legal practices and prohibitions is presented as a backdrop to the preferences and beliefs of the 1100+ million people in consanguineous unions. Chapters on population genetics, and the role of consanguinity in reproductive behaviour and genetic variation, set the scene for critical analyses of the influence of consanguinity on health in the early years of life. The discussion on consanguinity and disorders of adulthood is the first review of its kind and is particularly relevant given the ageing of the global population. Incest is treated as a separate issue, with historical and present-day examples examined. The final three chapters deal in detail with practical issues, including genetic testing, education and counselling, national and international legislation and imperatives, and the future of consanguineous marriage worldwide.

Consanguineous Marriages in the American Population

Consanguineous Marriages in the American Population PDF Author: George Byron Louis Arner
Publisher: New York : Columbia University Press, Longmans, Green, agents ; London : P.S. King
ISBN:
Category : Social Science
Languages : en
Pages : 120

Book Description


Consanguineous Marriages in the American Population

Consanguineous Marriages in the American Population PDF Author: George Byron Louis Arner
Publisher: Blacksleet River
ISBN: 1449977235
Category : Consanguinity
Languages : en
Pages : 104

Book Description


Vogel and Motulsky's Human Genetics

Vogel and Motulsky's Human Genetics PDF Author: Michael Speicher
Publisher: Springer Science & Business Media
ISBN: 3540376542
Category : Medical
Languages : en
Pages : 1006

Book Description
The fourth edition of this classical reference book can once again be relied upon to present a cohesive and up-to-date exposition of all aspects of human and medical genetics. Human genetics has become one of the main basic sciences in medicine, and molecular genetics is increasingly becoming a major part of this field. This new edition integrates a wealth of new information - mainly describing the influence of the "molecular revolution" - including the principles of epigenetic processes which together create the phenotype of a human being. Other revisions are an improved layout, sub-division into a larger number of chapters, as well as two-colour print throughout for ease of reference, and many of the figures are now in full colour. For graduates and those already working in medical genetics.

Forbidden Relatives

Forbidden Relatives PDF Author: Martin Ottenheimer
Publisher: University of Illinois Press
ISBN: 9780252065408
Category : Law
Languages : en
Pages : 194

Book Description
CONTENIDO: Laws prohibiting the marriage of relatives -- The reasons for U.S. laws against first cousin marriage -- European laws prohibiting the marriage of relatives -- European views of cousin marriage -- The evolutionary factor -- Biogenetics and first cousin marriage -- Culture and cousin marriage.

Negotiating Risk

Negotiating Risk PDF Author: Alison Shaw
Publisher: Berghahn Books
ISBN: 9781845455484
Category : Medical
Languages : en
Pages : 298

Book Description
Drawing on fieldwork with British Pakistani clients of a UK genetics service, this book explores the personal and social implications of a 'genetic diagnosis'. Through case material and comparative discussion, the book identifies practical ethical dilemmas raised by new genetic knowledge and shows how, while being shaped by culture, these issues also cross-cut differences of culture, religion and ethnicity. The book also demonstrates how identifying a population-level elevated 'risk' of genetic disorders in an ethnic minority population can reinforce existing social divisions and cultural stereotypes. The book addresses questions about the relationship between genetic risk and clinical practice that will be relevant to health workers and policy makers.

Migration, Ethnicity, Race, and Health in Multicultural Societies

Migration, Ethnicity, Race, and Health in Multicultural Societies PDF Author: Raj S. Bhopal
Publisher:
ISBN: 0199667861
Category : Medical
Languages : en
Pages : 388

Book Description
This book discusses the concepts of migration, race, and ethnicity and demonstrates how these can be applied in scientific research, policy making, health service planning, and health promotion. Extensive examples are used to demonstrate the application of the theory.

The WEIRDest People in the World

The WEIRDest People in the World PDF Author: Joseph Henrich
Publisher: Farrar, Straus and Giroux
ISBN: 0374710457
Category : Psychology
Languages : en
Pages : 420

Book Description
A New York Times Notable Book of 2020 A Bloomberg Best Non-Fiction Book of 2020 A Behavioral Scientist Notable Book of 2020 A Human Behavior & Evolution Society Must-Read Popular Evolution Book of 2020 A bold, epic account of how the co-evolution of psychology and culture created the peculiar Western mind that has profoundly shaped the modern world. Perhaps you are WEIRD: raised in a society that is Western, Educated, Industrialized, Rich, and Democratic. If so, you’re rather psychologically peculiar. Unlike much of the world today, and most people who have ever lived, WEIRD people are highly individualistic, self-obsessed, control-oriented, nonconformist, and analytical. They focus on themselves—their attributes, accomplishments, and aspirations—over their relationships and social roles. How did WEIRD populations become so psychologically distinct? What role did these psychological differences play in the industrial revolution and the global expansion of Europe during the last few centuries? In The WEIRDest People in the World, Joseph Henrich draws on cutting-edge research in anthropology, psychology, economics, and evolutionary biology to explore these questions and more. He illuminates the origins and evolution of family structures, marriage, and religion, and the profound impact these cultural transformations had on human psychology. Mapping these shifts through ancient history and late antiquity, Henrich reveals that the most fundamental institutions of kinship and marriage changed dramatically under pressure from the Roman Catholic Church. It was these changes that gave rise to the WEIRD psychology that would coevolve with impersonal markets, occupational specialization, and free competition—laying the foundation for the modern world. Provocative and engaging in both its broad scope and its surprising details, The WEIRDest People in the World explores how culture, institutions, and psychology shape one another, and explains what this means for both our most personal sense of who we are as individuals and also the large-scale social, political, and economic forces that drive human history. Includes black-and-white illustrations.

Growing Up Global

Growing Up Global PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 030909528X
Category : Social Science
Languages : en
Pages : 721

Book Description
The challenges for young people making the transition to adulthood are greater today than ever before. Globalization, with its power to reach across national boundaries and into the smallest communities, carries with it the transformative power of new markets and new technology. At the same time, globalization brings with it new ideas and lifestyles that can conflict with traditional norms and values. And while the economic benefits are potentially enormous, the actual course of globalization has not been without its critics who charge that, to date, the gains have been very unevenly distributed, generating a new set of problems associated with rising inequality and social polarization. Regardless of how the globalization debate is resolved, it is clear that as broad global forces transform the world in which the next generation will live and work, the choices that today's young people make or others make on their behalf will facilitate or constrain their success as adults. Traditional expectations regarding future employment prospects and life experiences are no longer valid. Growing Up Global examines how the transition to adulthood is changing in developing countries, and what the implications of these changes might be for those responsible for designing youth policies and programs, in particular, those affecting adolescent reproductive health. The report sets forth a framework that identifies criteria for successful transitions in the context of contemporary global changes for five key adult roles: adult worker, citizen and community participant, spouse, parent, and household manager.