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Author: Jie Jack Li Publisher: ISBN: 9780197609866 Category : Antiviral agents Languages : en Pages : 0
Book Description
"COVID-19 reminds us how acutely the virus can impact humanity. In fact, viruses existed long before the emergence of homo sapiens. In this book on the history of antiviral drug discovery, the human aspects are highlighted. In Chapter 1, the author regales us with several episodes where history was shaped by viruses causing smallpox, yellow fever, etc. The fascinating history of the first discovery of virus, tobacco mosaic virus, was also recounted. Chapters 2-5 covered four classes of viruses such as HIV, hepatitis viruses, influenza viruses and coronaviruses. Each chapter begins how the virus was discovered, followed by vaccine development, and then focuses on the discovery of small molecule antiviral drugs. For chemistry aficionados, the end of the book is replete with abundant of bibliography for further understanding of the minutia of the stories, followed by molecular structures of the antiviral drugs. This book is of interest to anyone who wants to know the science behind virus, vaccines and antiviral drugs. It is especially useful for healthcare professionals who are interested in knowing how viruses, vaccines and antiviral drugs are discovered"--
Author: Jie Jack Li Publisher: ISBN: 9780197609866 Category : Antiviral agents Languages : en Pages : 0
Book Description
"COVID-19 reminds us how acutely the virus can impact humanity. In fact, viruses existed long before the emergence of homo sapiens. In this book on the history of antiviral drug discovery, the human aspects are highlighted. In Chapter 1, the author regales us with several episodes where history was shaped by viruses causing smallpox, yellow fever, etc. The fascinating history of the first discovery of virus, tobacco mosaic virus, was also recounted. Chapters 2-5 covered four classes of viruses such as HIV, hepatitis viruses, influenza viruses and coronaviruses. Each chapter begins how the virus was discovered, followed by vaccine development, and then focuses on the discovery of small molecule antiviral drugs. For chemistry aficionados, the end of the book is replete with abundant of bibliography for further understanding of the minutia of the stories, followed by molecular structures of the antiviral drugs. This book is of interest to anyone who wants to know the science behind virus, vaccines and antiviral drugs. It is especially useful for healthcare professionals who are interested in knowing how viruses, vaccines and antiviral drugs are discovered"--
Author: Tom Shachtman Publisher: HMH ISBN: 0547525958 Category : Science Languages : en Pages : 275
Book Description
“A lovely, fascinating book, which brings science to life.” —Alan Lightman Combining science, history, and adventure, Tom Shachtman “holds the reader’s attention with the skill of a novelist” as he chronicles the story of humans’ four-centuries-long quest to master the secrets of cold (Scientific American). “A disarming portrait of an exquisite, ferocious, world-ending extreme,” Absolute Zero and the Conquest of Cold demonstrates how temperature science produced astonishing scientific insights and applications that have revolutionized civilization (Kirkus Reviews). It also illustrates how scientific advancement, fueled by fortuitous discoveries and the efforts of determined individuals, has allowed people to adapt to—and change—the environments in which they live and work, shaping man’s very understanding of, and relationship, with the world. This “truly wonderful book” was adapted into an acclaimed documentary underwritten by the National Science Foundation and the Alfred P. Sloan Foundation, directed by British Emmy Award winner David Dugan, and aired on the BBC and PBS’s Nova in 2008 (Library Journal). “An absorbing account to chill out with.” —Booklist
Author: Andrea Smith Publisher: Duke University Press ISBN: 0822374811 Category : Social Science Languages : en Pages : 127
Book Description
In this revolutionary text, prominent Native American studies scholar and activist Andrea Smith reveals the connections between different forms of violence—perpetrated by the state and by society at large—and documents their impact on Native women. Beginning with the impact of the abuses inflicted on Native American children at state-sanctioned boarding schools from the 1880s to the 1980s, Smith adroitly expands our conception of violence to include the widespread appropriation of Indian cultural practices by whites and other non-Natives; environmental racism; and population control. Smith deftly connects these and other examples of historical and contemporary colonialism to the high rates of violence against Native American women—the most likely to suffer from poverty-related illness and to survive rape and partner abuse. Smith also outlines radical and innovative strategies for eliminating gendered violence.
Author: Jie Jack Li Publisher: Oxford University Press ISBN: 0199362602 Category : Medical Languages : en Pages : 219
Book Description
Drugs like Lipitor, Plavix, Taxol, and Zoloft are integral in today's medicinal world. These widely used products save lives and improve the quality of lives, playing a crucial role in everything from cholesterol management to cancer treatment. These advances in medicine were brought into existence after nuanced process of creation, featuring a wide range of chemical and pharmacological experimentation and discovery. Top Drugs: Their History, Pharmacology, and Synthesis provides an in-depth study on ten prominent drugs, outlining the chemistry behind each one's creation. Jie Jack Li, a medicinal chemist and an expert on drug discovery, offers a thorough analysis of the landscape of current drug development. The comprehensive text is divided by health issues, including cardiovascular, cancer, metabolic diseases, and infectious diseases. Each section features individual chapters on significant drugs, outlining the chemistry and history of the drug's discovery. Li begins each chapter with the product's history, providing necessary context. Li then proceeds to describe the mechanism of action, structure-activity relationship (SAR), bioavailability, metabolism, toxicology, the discovery route, and the process route. Top Drugs: Their History, Pharmacology, and Synthesis will acclimate students, scientists, and interested laypersons to the world of chemistry and drug discovery.
Author: Simon Scarrow Publisher: ISBN: 9780747272830 Category : Great Britain Languages : en Pages : 310
Book Description
When Centurion Macro arrives on the shores of Britain to take part in the Emperor Claudius's invasion in the summer of AD 43, he knows he will be facing one of the toughest campaigns of his battle-scarred career. But nothing could have prepared him for the brutality and bravery of the British warriors. In a series of bloody battles, Macro and his young subordinate, Optio Cato, and the desperately outnumbered Roman army, must find and defeat the enemy before he can grow strong enough to overwhelm the legions. But the Britons are not the only foe facing Macro and Cato. A sinister organisation opposed to the Emperor is secretly betraying the brave men of the legions. And when rumours of an assassination attempt coincide with the Emperor's arrival on British soil, the soldiers realise they are up against a force more ruthless than their acknowledged enemy, and that time is running out if they are to prevent Claudius's glorious victory turning to disaster.
Author: Robert W. Merry Publisher: Simon and Schuster ISBN: 074329744X Category : Biography & Autobiography Languages : en Pages : 592
Book Description
ROBERT MERRY’S BRILLIANT AND HIGHLY ACCLAIMED HISTORY OF A CRUCIAL EPOCH IN U.S. HISTORY. In a one-term presidency, James K. Polk completed the story of America’s Manifest Destiny—extending its territory across the continent by threatening England with war and manufacturing a controversial and unpopular two-year war with Mexico.
Author: A. J. Prats Publisher: Cornell University Press ISBN: 9780801487545 Category : Indians in motion pictures Languages : en Pages : 348
Book Description
This incisive, provocative, and wide-ranging book casts a critical eye on the representation of Native Americans in the Western film since the genre's beginnings. Armando José Prats shows the ways in which film reflects cultural transformations in the course of America's historical encounter with "the Indian." He also explores the relation between the myth of conquest and American history. Among the films he discusses at length are Northwest Passage, Stagecoach, The Searchers, Hombre, Hondo, Ulzana's Raid, The Last of the Mohicans, and Dances With Wolves.Throughout, Prats emphasizes the irony that the Western seems to be able to represent Native Americans only by rendering them absent. In addition, he points out that Native Americans who appear in Westerns are almost always male; Native women rarely figure into the plot, and are often portrayed by white women rendered "Indian" by narrative necessity. Invisible Natives offers an intriguing view of the possibilities and consequences--as well as the historical sources and cultural origins--of the Western's strategies for evading the actual portrayal of Native Americans.
Author: Robert Fisk Publisher: Vintage ISBN: 0307428710 Category : History Languages : en Pages : 1415
Book Description
A sweeping and dramatic history of the last half century of conflict in the Middle East from an award-winning journalist who has covered the region for over forty years, The Great War for Civilisation unflinchingly chronicles the tragedy of the region from the Algerian Civil War to the Iranian Revolution; from the American hostage crisis in Beirut to the Iran-Iraq War; from the 1991 Gulf War to the American invasion of Iraq in 2003. A book of searing drama as well as lucid, incisive analysis, The Great War for Civilisation is a work of major importance for today's world.
Author: Werner Herzog Publisher: Harper Collins ISBN: 0062016466 Category : Biography & Autobiography Languages : en Pages : 324
Book Description
“Hypnotic….It is ever tempting to try to fathom his restless spirit and his determination to challenge fate.” —Janet Maslin, New York Times Werner Herzog (Grizzly Man) is one of the most revered and enigmatic filmmakers of our time, and Fitzcarraldo is one of his most honored and admired films. More than just Herzog’s journal of the making of the monumental, problematical motion picture, which involved, among other things, major cast changes and reshoots, and the hauling (without the use of special effects) of a 360-ton steamship over a mountain , Conquest of the Useless is a work of art unto itself, an Amazonian fever dream that emerged from the delirium of the jungle. With fascinating observations about crew and players—including Herzog’s lead, the somewhat demented internationally renowned star Klaus Kinski—and breathtaking insights into the filmmaking process that are uniquely Werner Herzog, Conquest of the Useless is an eye-opening look into the mind of a cinematic master.
Author: Jie Jack Li
Author: Jie Jack Li
Author: Tom Shachtman
Author: Andrea Smith
Author: Jie Jack Li
Author: Simon Scarrow
Author: Robert W. Merry
Author: A. J. Prats
Author: Robert Fisk
Author: Joseph Morony
Author: Werner Herzog