Author: Publisher:
ISBN:
Category : Antineoplastic agents
Languages : en
Pages : 162
Book Description
First Conference on DNA Topoisomerases in Cancer Chemotherapy
Author: Publisher:
ISBN:
Category : Antineoplastic agents
Languages : en
Pages : 162
Book Description
DNA Topoisomerases in Cancer
Author: Milan PotmesilPublisher: Oxford University Press, USA
ISBN:
Category : Medical
Languages : en
Pages : 364
Book Description
DNA Topoisomerases are a unique class of enzymes that are responsible for the control and modification of DNA topology (tertiary structure); one example of their function is the transformation of chromosomes from a supercoiled condensed state to uncoiled strands and vice versa. They are of interest both for their intrinsic role in cell biology (i.e. control of cell division) and also because some anticancer drugs, such as camptothecin, act by inhibiting their action.
NCI Monographs
Author: Molecular Biology of DNA Topoisomerases and Its Application to Chemotherapy
Author: Toshiwo AndohPublisher: CRC Press
ISBN: 9780849349706
Category : Medical
Languages : en
Pages : 400
Book Description
Molecular Biology of DNA Topoisomerases and Its Application to Chemotherapy is based on conference proceedings from the International Symposium on DNA Topoisomerases in Chemotherapy, held in Nagoya, Japan, in November 1991. The book opens with a discussion of the structural and functional properties of various types of DNA topoisomerases identified in prokaryotes and eukaryotes, in addition to their roles as cellular targets of anticancer and antimicrobial agents. Other topics addressed include the genetics and biology of DNA topoisomerases, inhibitors of microbial DNA topoisomerases and drug resistance, inhibitors of mammalian DNA topoisomerases and drug resistance, and preclinical and clinical studies of DNA topoisomerase inhibitors. Molecular Biology of DNA Topoisomerases and Its Application to Chemotherapy will broaden the understanding of biology and genetics of DNA topoisomerases and contribute to the development of antimicrobial and anticancer agents-inhibitors of topoisomerases. It will be invaluable for oncologists, molecular biologists, cellular biologists, geneticists, biochemists, and pharmaceutical researchers.
Journal of the National Cancer Institute
Author: Current Catalog
Author: National Library of Medicine (U.S.)Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1628
Book Description
First multi-year cumulation covers six years: 1965-70.
Research Awards Index
Author: Biomedical Index to PHS-supported Research: pt. A. Subject access A-H
Author: Biomedical Index to PHS-supported Research
Author: National Library of Medicine Current Catalog
Author: National Library of Medicine (U.S.)Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1178
Book Description