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Computation in Living Cells

Computation in Living Cells PDF Author: Andrzej Ehrenfeucht
Publisher: Springer Science & Business Media
ISBN: 3662063719
Category : Science
Languages : en
Pages : 202

Book Description
This is the first monograph on computation in living cells - one of the central and fastest growing areas of research in this field. Gene assembly in ciliates (unicellular organisms) is a splendid example of such computations. This work has helped to clarify important biological aspects of gene assembly, yielded novel insights into the nature of computation, and broadened our understanding of what computation is about. The monograph gives an accessible account of both the biology and the formal analysis of the gene assembly process. It can be used as a textbook for either graduate courses or seminars.

Computation in Living Cells

Computation in Living Cells PDF Author: Andrzej Ehrenfeucht
Publisher: Springer Science & Business Media
ISBN: 3662063719
Category : Science
Languages : en
Pages : 202

Book Description
This is the first monograph on computation in living cells - one of the central and fastest growing areas of research in this field. Gene assembly in ciliates (unicellular organisms) is a splendid example of such computations. This work has helped to clarify important biological aspects of gene assembly, yielded novel insights into the nature of computation, and broadened our understanding of what computation is about. The monograph gives an accessible account of both the biology and the formal analysis of the gene assembly process. It can be used as a textbook for either graduate courses or seminars.

Wetware

Wetware PDF Author: Dennis Bray
Publisher: Yale University Press
ISBN: 0300155441
Category : Science
Languages : en
Pages : 280

Book Description
“A beautifully written journey into the mechanics of the world of the cell, and even beyond, exploring the analogy with computers in a surprising way” (Denis Noble, author of Dance to the Tune of Life). How does a single-cell creature, such as an amoeba, lead such a sophisticated life? How does it hunt living prey, respond to lights, sounds, and smells, and display complex sequences of movements without the benefit of a nervous system? This book offers a startling and original answer. In clear, jargon-free language, Dennis Bray taps the findings from the discipline of systems biology to show that the internal chemistry of living cells is a form of computation. Cells are built out of molecular circuits that perform logical operations, as electronic devices do, but with unique properties. Bray argues that the computational juice of cells provides the basis for all distinctive properties of living systems: it allows organisms to embody in their internal structure an image of the world, and this accounts for their adaptability, responsiveness, and intelligence. In Wetware, Bray offers imaginative, wide-ranging, and perceptive critiques of robotics and complexity theory, as well as many entertaining and telling anecdotes. For the general reader, the practicing scientist, and all others with an interest in the nature of life, this book is an exciting portal to some of biology’s latest discoveries and ideas. “Drawing on the similarities between Pac-Man and an amoeba and efforts to model the human brain, this absorbing read shows that biologists and engineers have a lot to learn from working together.” —Discover magazine “Wetware will get the reader thinking.” —Science magazine

Computational Cell Biology

Computational Cell Biology PDF Author: Christopher P. Fall
Publisher: Springer Science & Business Media
ISBN: 0387224599
Category : Science
Languages : en
Pages : 484

Book Description
This textbook provides an introduction to dynamic modeling in molecular cell biology, taking a computational and intuitive approach. Detailed illustrations, examples, and exercises are included throughout the text. Appendices containing mathematical and computational techniques are provided as a reference tool.

Data Book on Mechanical Properties of Living Cells, Tissues, and Organs

Data Book on Mechanical Properties of Living Cells, Tissues, and Organs PDF Author: Hiroyuki Abe
Publisher: Springer Science & Business Media
ISBN: 4431658629
Category : Technology & Engineering
Languages : en
Pages : 443

Book Description
A research project entitled Biomechanics of Structure and Function of Living Cells, Tissues, and Organs was launched in Japan in 1992. This data book presents the original, up-to-date information resulting from the research project, supplemented by some of the important basic data published previously. The aim of collecting the information is to offer accurate and useful data on the mechanical properties of living materials to biomechanical scientists, biomedical engineers, medical scientists, and clinicians. The data are presented in graphs and tables (one type of data per page) arranged in an easily accessible manner, along with details of the origin of the material and the experimental method. Together with its two companion volumes, Biomechanics: Functional Adaptation and Remodeling and Computational Biomechanics, the Data Book on Mechanical Properties of Living Cells, Tissues, and Organs is a timely and valuable contribution to the rapidly growing field of biomechanics.

Ultra Low Power Bioelectronics

Ultra Low Power Bioelectronics PDF Author: Rahul Sarpeshkar
Publisher: Cambridge University Press
ISBN: 1139485237
Category : Technology & Engineering
Languages : en
Pages : 909

Book Description
This book provides, for the first time, a broad and deep treatment of the fields of both ultra low power electronics and bioelectronics. It discusses fundamental principles and circuits for ultra low power electronic design and their applications in biomedical systems. It also discusses how ultra energy efficient cellular and neural systems in biology can inspire revolutionary low power architectures in mixed-signal and RF electronics. The book presents a unique, unifying view of ultra low power analog and digital electronics and emphasizes the use of the ultra energy efficient subthreshold regime of transistor operation in both. Chapters on batteries, energy harvesting, and the future of energy provide an understanding of fundamental relationships between energy use and energy generation at small scales and at large scales. A wealth of insights and examples from brain implants, cochlear implants, bio-molecular sensing, cardiac devices, and bio-inspired systems make the book useful and engaging for students and practicing engineers.

Cell-Free Synthetic Biology

Cell-Free Synthetic Biology PDF Author: Yuan Lu
Publisher: Springer
ISBN: 9811311714
Category : Technology & Engineering
Languages : en
Pages : 42

Book Description
This book describes advanced studies in cell-free synthetic biology, an emerging biotechnology that focuses on cell-free protein synthesis and cell-free systems for fundamental and industrial research in areas such as genetic circuit design, small-molecule synthesis, complicated-macromolecule synthesis, unnatural-macromolecule synthesis, high-throughput screening, artificial cells, and biomaterials. Cell-free synthetic biology is now an integral part of developing fields like nanotechnology, materials science, and personalized medicine. The book discusses the main research directions in the development of cell-free systems, as well as a number of applications of cell-free synthetic biology, ranging from structural biology to the human health industry. It is intended for students and researchers in life sciences, synthetic biology, bioengineering, and chemical engineering.

Cell Movements

Cell Movements PDF Author: Dennis Bray
Publisher: Garland Science
ISBN: 9780815332824
Category : Cells
Languages : en
Pages : 396

Book Description
This book vividly describes how complex and integrated movements can arise from the properties and behaviors of biological molecules. It provides a uniquely integrated account in which the latest findings from biophysics and molecular biology are put into the context of living cells. This second edition is updated throughout with recent advances in the field and has a completely revised and redrawn art program. The text is suitable for advanced undergraduates, graduate students, and for professionals wishing for an overview of this field.

The Science and Applications of Synthetic and Systems Biology

The Science and Applications of Synthetic and Systems Biology PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309219396
Category : Science
Languages : en
Pages : 570

Book Description
Many potential applications of synthetic and systems biology are relevant to the challenges associated with the detection, surveillance, and responses to emerging and re-emerging infectious diseases. On March 14 and 15, 2011, the Institute of Medicine's (IOM's) Forum on Microbial Threats convened a public workshop in Washington, DC, to explore the current state of the science of synthetic biology, including its dependency on systems biology; discussed the different approaches that scientists are taking to engineer, or reengineer, biological systems; and discussed how the tools and approaches of synthetic and systems biology were being applied to mitigate the risks associated with emerging infectious diseases. The Science and Applications of Synthetic and Systems Biology is organized into sections as a topic-by-topic distillation of the presentations and discussions that took place at the workshop. Its purpose is to present information from relevant experience, to delineate a range of pivotal issues and their respective challenges, and to offer differing perspectives on the topic as discussed and described by the workshop participants. This report also includes a collection of individually authored papers and commentary.

An Introduction to Systems Biology

An Introduction to Systems Biology PDF Author: Uri Alon
Publisher: CRC Press
ISBN: 1584886420
Category : Mathematics
Languages : en
Pages : 324

Book Description
Thorough and accessible, this book presents the design principles of biological systems, and highlights the recurring circuit elements that make up biological networks. It provides a simple mathematical framework which can be used to understand and even design biological circuits. The textavoids specialist terms, focusing instead on several well-studied biological systems that concisely demonstrate key principles. An Introduction to Systems Biology: Design Principles of Biological Circuits builds a solid foundation for the intuitive understanding of general principles. It encourages the reader to ask why a system is designed in a particular way and then proceeds to answer with simplified models.

Cell Biology by the Numbers

Cell Biology by the Numbers PDF Author: Ron Milo
Publisher: Garland Science
ISBN: 1317230698
Category : Science
Languages : en
Pages : 399

Book Description
A Top 25 CHOICE 2016 Title, and recipient of the CHOICE Outstanding Academic Title (OAT) Award. How much energy is released in ATP hydrolysis? How many mRNAs are in a cell? How genetically similar are two random people? What is faster, transcription or translation?Cell Biology by the Numbers explores these questions and dozens of others provid