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Author: Derek H. R. Barton Publisher: Pergamon ISBN: Category : Science Languages : en Pages : 492
Book Description
Hardbound. This volume covers the dramatic advances which have been made in the lasttwo decades in the understanding of isoprenoid biosynthesis at thechemical, biochemical, and molecular genetic level. Tens of thousands ofisoprenoid metabolites - from pinenes to cholesterol, from ubiquinone tocarotene, from phytols to prenylated proteins, from dolichols togibberellins - have been isolated from essentially all forms of life, including prokaryotes, eukaryotes, and archaebacteria: from Escherichiacoli to mammals, from extremophiles and fungi to marine and terrestrialplants. All of these isoprenoids can be derived from a single, five-carbonacyclic precursor, isopentenyl diphosphate. Early chapters in this Volumedetail the key findings that have led to an understanding of the metabolicpathways leading to isopentenyl diphosphate, including both the classicalroute involving mevalonic acid as well as the recently discoveredpyruvate-triose phosphat
Author: Derek H. R. Barton Publisher: Pergamon ISBN: Category : Science Languages : en Pages : 492
Book Description
Hardbound. This volume covers the dramatic advances which have been made in the lasttwo decades in the understanding of isoprenoid biosynthesis at thechemical, biochemical, and molecular genetic level. Tens of thousands ofisoprenoid metabolites - from pinenes to cholesterol, from ubiquinone tocarotene, from phytols to prenylated proteins, from dolichols togibberellins - have been isolated from essentially all forms of life, including prokaryotes, eukaryotes, and archaebacteria: from Escherichiacoli to mammals, from extremophiles and fungi to marine and terrestrialplants. All of these isoprenoids can be derived from a single, five-carbonacyclic precursor, isopentenyl diphosphate. Early chapters in this Volumedetail the key findings that have led to an understanding of the metabolicpathways leading to isopentenyl diphosphate, including both the classicalroute involving mevalonic acid as well as the recently discoveredpyruvate-triose phosphat
Author: Anne E. Osbourn Publisher: Springer Science & Business Media ISBN: 0387854983 Category : Science Languages : en Pages : 588
Book Description
Plants produce a huge array of natural products (secondary metabolites). These compounds have important ecological functions, providing protection against attack by herbivores and microbes and serving as attractants for pollinators and seed-dispersing agents. They may also contribute to competition and invasiveness by suppressing the growth of neighboring plant species (a phenomenon known as allelopathy). Humans exploit natural products as sources of drugs, flavoring agents, fragrances and for a wide range of other applications. Rapid progress has been made in recent years in understanding natural product synthesis, regulation and function and the evolution of metabolic diversity. It is timely to bring this information together with contemporary advances in chemistry, plant biology, ecology, agronomy and human health to provide a comprehensive guide to plant-derived natural products. Plant-derived natural products: synthesis, function and application provides an informative and accessible overview of the different facets of the field, ranging from an introduction to the different classes of natural products through developments in natural product chemistry and biology to ecological interactions and the significance of plant-derived natural products for humans. In the final section of the book a series of chapters on new trends covers metabolic engineering, genome-wide approaches, the metabolic consequences of genetic modification, developments in traditional medicines and nutraceuticals, natural products as leads for drug discovery and novel non-food crops.
Author: Finian J. Leeper Publisher: Springer ISBN: 354048146X Category : Technology & Engineering Languages : en Pages : 255
Book Description
This book is the second of two volumes that deal with discovery of chemical pathways of biosynthesis of natural products (secondary metabolites). The first volume covered the use of isotopes in biosynthetic research and the formation of enzyme cofactors and reduced polyketides. This second volume describes biosynthesis of aromatic (unreduced) polyketides, enzymes responsible for cyclization of terpenoids (isoprenoids), and biochemical generation of selected classes of alkaloids (prenylated tryptophan, tropane, pyrrolizidine). Knowledge of the pathways and the techniques to elucidate them opens the door to combinatorial biosynthesis as well as to the production of targeted pharmaceutical agents utilizing a combination of chemistry, molecular biology and protein biochemistry.
Author: John Romeo Publisher: Elsevier ISBN: 0080474330 Category : Science Languages : en Pages : 280
Book Description
The chapters presented in Secondary Metabolism in Model Systems are a microcosm of what the recent completion, or near completion, of various genome projects are enabling biochemists to understand not only about control and regulation of secondary metabolism, and how various pathways relate to each other, but also about its relation to primary metabolism. A major paradigm shift is occurring in the way researchers need to view "secondary" metabolism in the future.It is also clear that model systems, such as the ones discussed in the symposium, are providing new information and insight almost faster than researchers can process it! The volumes in this series contain articles on developing topics of interest to scientists, students and individuals interested in recent developments in the biochemistry, chemistry and molecular biology of plants. An excellent series volume covering the advances in understanding of gene functions, a high profile area of research due to recent genome projects This book provides essential information on new model systems available to biochemists The chapters in this volume are based on the papers presented in the symposium entitled "Secondary Metabolism in Model Systems"
Author: Charles Ainsworth Publisher: John Wiley & Sons ISBN: 1405172401 Category : Science Languages : en Pages : 320
Book Description
The flowering plants now dominate the terrestrial ecosystems of theplanet, and there are good reasons for supposing that the floweritself has been a major contributing factor to the spread of theAngiosperms. The flowers of higher plants not only contain theorgans of plant reproduction but are of fundamental importance ingiving rise to fruits and seeds which constitute a major componentof the human diet. This volume opens with a chapter describing a model for theevolution of the Angiosperm flower. Chapters 2 to 5 describe thecore development of the flower and include floral induction, floralpattering and organ initiation, floral shape and size, andinflorescence architecture. Chapters 6 to 8 focus on morespecialised aspects of floral development: monoecy, cytoplasmicmale sterility and flowering in perennials. Chapters 9 and 10address more functional aspects: flower colour and scent. The bookconcludes, appropriately, with a chapter on flowersenescence. Applied aspects are stressed wherever appropriate, and the book isdirected at researchers and professionals in plant genetics,developmental and molecular biology. The volume has been designed to complement an earlier volume in ourAnnual Plant Reviews series, O'Neill, S. D. and Roberts, J. A.(2002) Plant Reproduction.
Author: Christopher B Johnson Publisher: CRC Press ISBN: 9780789019738 Category : Science Languages : en Pages : 464
Book Description
The field of medicinal/aromatic plant breeding is growing and changing?this resource will help you stay up to date! In this essential book, researchers from large and small laboratories and institutions throughout Europe and the Mediterranean region explore recent developments in the selection and breeding of aromatic and medicinal plants. They take varied approaches?from traditional breeding to the use of molecular markers?and complement them with up-to-date information on biodiversity and resource conservation. From the editors: ?It is widely recognized that a strategy of `conservation through use,? by which plant collection via wild harvesting is replaced by controlled cultivation, is the best way forward if we are to balance human demands with the necessary conservation of the biodiversity represented by these species. That provides one major driving force for research in this field. Another concerns the very real need for improving the quality control of products on the market, both to satisfy consumer demand and to conform with the (justifiably) increasing requirements for standardization and precise identification of the composition of the plant materials being sold for human use. We hope that this volume will give readers a taste of the exciting developments in the field.? Breeding Research on Aromatic and Medicinal Plants examines: breeding for resistance and abiotic factors manipulating natural product accumulation through genetic engineering biochemical and molecular regulation of essential oil accumulation economic and legal considerations that breeders will encounter the ethical aspects of breeding these plants
Author: Bimal Krishna Banik Publisher: CRC Press ISBN: 1000823490 Category : Science Languages : en Pages : 633
Book Description
Activities and biological relationships of terpenes. An accurate assessment of where and what terpenes can lead to. Discusses how microbes, in particular the actinomycetales, have well over 400 different gene clusters that produce terpenes. Arranged by biological activities and usage. Provides information on eukaryotic enzymes that have been shown to be a source of “ethnobotanical” terpenes
Author: Robert L. Wixom Publisher: John Wiley & Sons ISBN: 1118060296 Category : Science Languages : en Pages : 357
Book Description
Leading researchers discuss the past and present of chromatography More than one hundred years after Mikhail Tswett pioneered adsorption chromatography, his separation technique has developed into an important branch of scientific study. Providing a full portrait of the discipline, Chromatography: A Science of Discovery bridges the gap between early, twentieth-century chromatography and the cutting edge of today’s research. Featuring contributions from more than fifty award-winning chromatographers, Chromatography offers a multifaceted look at the development and maturation of this field into its current state, as well as its importance across various scientific endeavors. The coverage includes: Consideration of chromatography as a unified science rather than just a separation method Key breakthroughs, revolutions, and paradigm shifts in chromatography Profiles of Nobel laureates who used chromatography in their research, and the role it played Recent advances in column technology Chromatography’s contributions to the agricultural, space, biological/medical sciences; pharmaceutical science; and environmental, natural products, and chemical analysis Future trends in chromatography With numerous references and an engaging series of voices, Chromatography: A Science of Discovery offers a diverse look at an essential area of science. It is a unique and invaluable resource for researchers, students, and other interested readers who seek a broader understanding of this field.