Comparative Immunology of Marine Mammals PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Comparative Immunology of Marine Mammals PDF full book. Access full book title Comparative Immunology of Marine Mammals by Giovanni Di Guardo. Download full books in PDF and EPUB format.
Author: Giovanni Di Guardo Publisher: Frontiers Media SA ISBN: 2889632032 Category : Languages : en Pages : 101
Book Description
Marine mammals (MMs) are regarded as valuable bioindicators with tremendous potential for public health. However, many aspects of their immune system remain poorly understood. Monitoring immune responses of MMs is pivotal for the health assessment of both individuals and populations, as well as providing the scientific basis for analyzing the anthropogenic environmental impact on marine ecosystems and marine-terrestrial interphases. For instance, the increasing susceptibility of Mediterranean whale and dolphin populations to various diseases has been linked to a possible negative influence of multiple environmental factors on the immune system of MMs. The currently limited knowledge on MM immunology has mainly centered on: (i) lymphocyte transformation assays; (ii) natural killer cell activity; (iii) phagocytic activity and respiratory burst; (iv) humoral immune responses; (v) cytokines and (vi) acute phase immune responses. Therefore, further research is essential for deepening our understanding of the specificity of the host immune response in MMs, with a particular emphasis on the genesis and dynamics of (i) cytokine ‘networks’ or ‘signatures’; (ii) transcriptional regulation of immune cells and (iii) major immunomodulators. High-throughput molecular techniques, such as transcriptomic analysis and RNA sequencing, may enable the characterization of immune gene responses at the transcriptomic level. This integrative and holistic approach requires sophisticated tools and methods capable of unveiling the diversity of immune cells and immunologically relevant molecules that orchestrate environmental adaptation and immune protection against pathogens in MMs. This Research Topic aims to provide a comprehensive overview of the current knowledge of MM immunology with a particular emphasis on structural and functional studies at the protein and cellular level. We wish to encourage and coordinate studies and investigations in order to fill gaps of knowledge in this field. This article collection aims to help gain more data regarding: a) The characterization of the immune system in several species of MMs, i.e. cetaceans, pinnipeds and sirenians; b) The interplay between the host immune system and the most relevant pathogens, e.g., Morbillivirus, Brucella, Toxoplasma gondii and c) The possible interplay between the immune system and contaminants.
Author: Giovanni Di Guardo Publisher: Frontiers Media SA ISBN: 2889632032 Category : Languages : en Pages : 101
Book Description
Marine mammals (MMs) are regarded as valuable bioindicators with tremendous potential for public health. However, many aspects of their immune system remain poorly understood. Monitoring immune responses of MMs is pivotal for the health assessment of both individuals and populations, as well as providing the scientific basis for analyzing the anthropogenic environmental impact on marine ecosystems and marine-terrestrial interphases. For instance, the increasing susceptibility of Mediterranean whale and dolphin populations to various diseases has been linked to a possible negative influence of multiple environmental factors on the immune system of MMs. The currently limited knowledge on MM immunology has mainly centered on: (i) lymphocyte transformation assays; (ii) natural killer cell activity; (iii) phagocytic activity and respiratory burst; (iv) humoral immune responses; (v) cytokines and (vi) acute phase immune responses. Therefore, further research is essential for deepening our understanding of the specificity of the host immune response in MMs, with a particular emphasis on the genesis and dynamics of (i) cytokine ‘networks’ or ‘signatures’; (ii) transcriptional regulation of immune cells and (iii) major immunomodulators. High-throughput molecular techniques, such as transcriptomic analysis and RNA sequencing, may enable the characterization of immune gene responses at the transcriptomic level. This integrative and holistic approach requires sophisticated tools and methods capable of unveiling the diversity of immune cells and immunologically relevant molecules that orchestrate environmental adaptation and immune protection against pathogens in MMs. This Research Topic aims to provide a comprehensive overview of the current knowledge of MM immunology with a particular emphasis on structural and functional studies at the protein and cellular level. We wish to encourage and coordinate studies and investigations in order to fill gaps of knowledge in this field. This article collection aims to help gain more data regarding: a) The characterization of the immune system in several species of MMs, i.e. cetaceans, pinnipeds and sirenians; b) The interplay between the host immune system and the most relevant pathogens, e.g., Morbillivirus, Brucella, Toxoplasma gondii and c) The possible interplay between the immune system and contaminants.
Author: Ian R Tizard Publisher: Elsevier ISBN: 0323952208 Category : Medical Languages : en Pages : 460
Book Description
Comparative Mammalian Immunology: The Evolution and Diversity of the Immune Systems of Mammals provides a review on the current knowledge of mammalian immune systems from a comparative viewpoint. This reference encompasses recent work on the immune systems of marine mammals, bats and marsupials in addition to other lesser-known species, with the immune systems of humans and laboratory mice as components of chapters on primates and rodents respectively. The book also makes use of the most recent studies on the genomic sequences of the mammals to identify both common and unique features of each mammal's immune system. The book elucidates the complex, but coordinated and controlled series of interactions involving cells and molecules that has evolved to protect the host against disease. Mammals consist of a highly diverse group of animals in which the immune system has been subjected to a variety of selective pressures. This is reflected in differences in the organization and function of their immune systems, and is especially seen in those gene families characterized by complexity and polymorphism. Demonstrates multiple diverse pathways and mechanisms to optimize resistance and survival in the face of infectious diseases Shows the clear patterns of emergence of different immunologic traits among the diverse orders of mammals Reflects issues with innate or adaptive immune systems Serves as a comprehensive review of the current state of knowledge of the immune system of each mammalian order
Author: Edwin L. Cooper Publisher: Springer ISBN: 3319767682 Category : Medical Languages : en Pages : 1048
Book Description
Immunologists, perhaps understandably, most often concentrate on the human immune system, an anthropocentric focus that has resulted in a dearth of information about the immune function of all other species within the animal kingdom. However, knowledge of animal immune function could help not only to better understand human immunology, but perhaps more importantly, it could help to treat and avoid the blights that affect animals, which consequently affect humans. Take for example the mass death of honeybees in recent years – their demise, resulting in much less pollination, poses a serious threat to numerous crops, and thus the food supply. There is a similar disappearance of frogs internationally, signaling ecological problems, among them fungal infections. This book aims to fill this void by describing and discussing what is known about non-human immunology. It covers various major animal phyla, its chapters organized in a progression from the simplest unicellular organisms to the most complex vertebrates, mammals. Chapters are written by experts, covering the latest findings and new research being conducted about each phylum. Edwin L. Cooper is a Distinguished Professor in the Laboratory of Comparative Immunology, Department of Neurobiology at UCLA’s David Geffen School of Medicine.
Author: Edwin B. Howard Publisher: CRC Press ISBN: 1351092324 Category : Medical Languages : en Pages : 256
Book Description
These volumes provide information which will be helpful to comparative pathologists, veterinarians, and all marine scientists and other individuals who are interested in the study of marine mammals, and the diseases they develop in both their feral and captive environment.This publication is a reflection of the observations of the various authors, some of whom have pioneered in this field, and is an attempt to update the available information concerning the natural diseases, and the corresponding pathologic changes in marine mammals.
Author: Howard Publisher: CRC Press ISBN: 1351092316 Category : Medical Languages : en Pages : 254
Book Description
These volumes provide information which will be helpful to comparative pathologists, veterinarians, and all marine scientists and other individuals who are interested in the study of marine mammals, and the diseases they develop in both their feral and captive environment.This publication is a reflection of the observations of the various authors, some of whom have pioneered in this field, and is an attempt to update the available information concerning the natural diseases, and the corresponding pathologic changes in marine mammals.
Author: Michael A. Castellini Publisher: CRC Press ISBN: 1482242699 Category : Medical Languages : en Pages : 384
Book Description
Suppose you were designing a marine mammal. What would you need to think about to allow it to live in the ocean? How would you keep it warm? What would you design to allow it to dive for very long periods to extreme depths? Where would it find water to drink? How would you minimize the cost of swimming, and how would it find its prey in the deep an
Author: Publisher: ISBN: Category : Languages : en Pages : 3
Book Description
Knowledge of the interrelationship of stress, immunology and infectious disease is basic to management of preventive medicine programs. Diagnostic and prognostic indicators of the dynamics of this interrelationship are not as well defined in marine mammals as they are in terrestrial animals. Our objectives were to correlate a newly developed immune system indicator, radioimmunoassay of immunoglobulins, with some indicators of stress: erythrocyte sedimentation rate, serum cortisol levels, eosinophil numbers, free iron in serum, blood gasses and more traditional complete blood counts, to determine some effects of stressors on the immune system of five newly collected Tursiops truncatus gilli. This data was analyzed and related to the dolphins' response to changes in bacteria cultured from their blow holes. Analysis of periodic blood samples indicated increased sedimentation rates within one week and decreasing sperm iron correlated with the change in bacterial flora from Vibrio alginolyticus, (normal in dolphins in Hawaii), to coagulase positive, Beta hemolytic, penicillin resistant Staphlycoccus aureus. Several other parameters were measured and correlated with the progression of disease processes, from the collection data through adjustments to captivity. Application of new technology in stress assessment, epidemiology and immunology of marine mammals was important in health management decisions for these newly captured dolphins. Reprints. (sdw).
Author: Giovanni Di Guardo
Author: Giovanni Di Guardo
Author: Ian R Tizard
Author: Gyri T. Haugland
Author: Edwin L. Cooper
Author: Edwin B. Howard
Author: Howard
Author: Michael A. Castellini
Author: 
Author: National Institutes of Health (U.S.). Division of Research Grants
Author: