Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download The Speed Culture PDF full book. Access full book title The Speed Culture by Lester Grinspoon. Download full books in PDF and EPUB format.
Author: Lester Grinspoon Publisher: Harvard University Press ISBN: 9780674831926 Category : Medical Languages : en Pages : 360
Book Description
Describes the popular rationals for and social forces motivating amphetamine use in America and the often physically and psychologically damaging effects of the drugs.
Author: Lester Grinspoon Publisher: Harvard University Press ISBN: 9780674831926 Category : Medical Languages : en Pages : 360
Book Description
Describes the popular rationals for and social forces motivating amphetamine use in America and the often physically and psychologically damaging effects of the drugs.
Author: Miriam Beloglovsky Publisher: Redleaf Press ISBN: 1605544655 Category : Education Languages : en Pages : 295
Book Description
Loose parts capture children's curiosity, give free reign to their imagination, and encourage creativity. This form of play allows infants to be in control and recognize the power of their bodies and actions. A variety of new and innovative loose parts ideas are paired with beautiful photography to inspire safe loose parts play in your infant and toddler environments. Captivating classroom stories and proven science provide the context for how this style of play supports children's development and learning. This book is perect for Montessori and Reggio-inspired programs and educators.
Author: Chris Holland Publisher: SAS Institute ISBN: 1642952419 Category : Computers Languages : en Pages : 358
Book Description
For decades researchers and programmers have used SAS to analyze, summarize, and report clinical trial data. Now Chris Holland and Jack Shostak have updated their popular Implementing CDISC Using SAS, the first comprehensive book on applying clinical research data and metadata to the Clinical Data Interchange Standards Consortium (CDISC) standards. Implementing CDISC Using SAS: An End-to-End Guide, Revised Second Edition, is an all-inclusive guide on how to implement and analyze the Study Data Tabulation Model (SDTM) and the Analysis Data Model (ADaM) data and prepare clinical trial data for regulatory submission. Updated to reflect the 2017 FDA mandate for adherence to CDISC standards, this new edition covers creating and using metadata, developing conversion specifications, implementing and validating SDTM and ADaM data, determining solutions for legacy data conversions, and preparing data for regulatory submission. The book covers products such as Base SAS, SAS Clinical Data Integration, and the SAS Clinical Standards Toolkit, as well as JMP Clinical. Topics included in this edition include an implementation of the Define-XML 2.0 standard, new SDTM domains, validation with Pinnacle 21 software, event narratives in JMP Clinical, STDM and ADAM metadata spreadsheets, and of course new versions of SAS and JMP software. The second edition was revised to add the latest C-Codes from the most recent release as well as update the make_define macro that accompanies this book in order to add the capability to handle C-Codes. The metadata spreadsheets were updated accordingly. Any manager or user of clinical trial data in this day and age is likely to benefit from knowing how to either put data into a CDISC standard or analyzing and finding data once it is in a CDISC format. If you are one such person--a data manager, clinical and/or statistical programmer, biostatistician, or even a clinician--then this book is for you.
Author: Congressional Budget Office Publisher: Lulu.com ISBN: 1304121445 Category : Science Languages : en Pages : 65
Book Description
Perceptions that the pace of new-drug development has slowed and that the pharmaceutical industry is highly profitable have sparked concerns that significant problems loom for future drug development. This Congressional Budget Office (CBO) study-prepared at the request of the Senate Majority Leader-reviews basic facts about the drug industry's recent spending on research and development (R&D) and its output of new drugs. The study also examines issues relating to the costs of R&D, the federal government's role in pharmaceutical research, the performance of the pharmaceutical industry in developing innovative drugs, and the role of expected profits in private firms' decisions about investing in drug R&D. In keeping with CBO's mandate to provide objective, impartial analysis, the study makes no recommendations. David H. Austin prepared this report under the supervision of Joseph Kile and David Moore. Colin Baker provided valuable consultation...
Author: Kavi Kishor P.B. Publisher: Springer ISBN: 8132218809 Category : Science Languages : en Pages : 296
Book Description
A common approach to understanding the functional repertoire of a genome is through functional genomics. With systems biology burgeoning, bioinformatics has grown to a larger extent for plant genomes where several applications in the form of protein-protein interactions (PPI) are used to predict the function of proteins. With plant genes evolutionarily conserved, the science of bioinformatics in agriculture has caught interest with myriad of applications taken from bench side to in silico studies. A multitude of technologies in the form of gene analysis, biochemical pathways and molecular techniques have been exploited to an extent that they consume less time and have been cost-effective to use. As genomes are being sequenced, there is an increased amount of expression data being generated from time to time matching the need to link the expression profiles and phenotypic variation to the underlying genomic variation. This would allow us to identify candidate genes and understand the molecular basis/phenotypic variation of traits. While many bioinformatics methods like expression and whole genome sequence data of organisms in biological databases have been used in plants, we felt a common reference showcasing the reviews for such analysis is wanting. We envisage that this dearth would be facilitated in the form of this Springer book on Agricultural Bioinformatics. We thank all the authors and the publishers Springer, Germany for providing us an opportunity to review the bioinformatics works that the authors have carried in the recent past and hope the readers would find this book attention grabbing.
Author: Michael J. Klepper Publisher: Jones & Bartlett Publishers ISBN: 1449671551 Category : Medical Languages : en Pages : 332
Book Description
Drug Safety Data: How to Analyze, Summarize and Interpret to Determine Risk was selected for The First Clinical Research Bookshelf - Essential reading for clinical research professionals by the Journal of Clinical Research Best Practices. Drug Safety Data: How to Analyze, Summarize and Interpret to Determine Risk provides drug safety/pharmacovogilance professionals, pharmaceutical and clinical research scientists, statisticians, programmers, medical writers, and technicians with an accessible, practical framework for the analysis, summary and interpretation of drug safety data. The only guide of its kind, Drug Safety Data: How to Analyze, Summarize and Interpret to Determine Risk is an invaluable reference for pre- and post-marketing risk assessment. With decades of pharmaceutical research and drug safety expertise, authors Dr. Klepper and Dr. Cobert discuss how quality planning, safety training, and data standardization result in significant cost, time, and resource savings. Through illustrative, step-by-step instruction, Drug Safety Data: How to Analyze, Summarize and Interpret to Determine Risk is the definitive guide to drug safety data analysis and reporting. Key features include: * Step-by-step instruction on how to analyze, summarize and interpret safety data for mandatory governmental safety reports * Pragmatic tips...and mistakes to avoid * Simple explanations of what safety data are collected, and what the data mean * Practical approaches to determining a drug effect and understanding its clinical significance * Guidance for determining risk throughout the lifecycle of a drug, biologic or nutraceutical * Examples of user-friendly data displays that enhance safety signal identification * Ways to improve data quality and reduce the time, resources and costs involved in mandatory safety reporting * Relevant material for the required training of drug safety/pharmacovigilance professionals * SPECIAL FEATURE: Actual examples of an Integrated Analysis of Safety (IAS) -used in the preparation of the Integrated Summary of Safety (ISS) and the Summary of Clinical Safety (SCS) reports -, and the Periodic Safety Update Report (PSUR)
Author: Jochen Schomacher Publisher: Thieme ISBN: 3131714611 Category : Medical Languages : en Pages : 750
Book Description
Proven and effective orthopedic therapy techniques for musculoskeletal disorders Orthopedic Manual Therapy presents a systematic, step-by-step guide to manual therapy for disorders of the extremities and spine. Readers will find detailed examination and treatment techniques, the newest scientific and clinical advances, and updates on pain physiology, biomechanics, neurodynamics, and the biopsychosocial model of disease as the foundation for manual therapy. Special Features Describes every procedure in well structured, logical sequences of assessment, classification, and intervention, including core questions for patients Covers examination and treatment of all joints, from the toes to the shoulder girdle, with new information on the sacro-iliac joint tests, as well as additional new techniques for the wrist and the hindfoot Provides more than 500 full-color, step-by-step photographs that illustrate every technique for treating functional disorders of the locomotor system Explains the important topic of arthrokinematics (movement of the adjacent joint surfaces) and its role in the mechanics of manual therapy Offers a practical documentation template for recording each articulation and communicating findings to colleagues or physicians Access to 20 instructive videos on the Thieme MediaCenter that demonstrate procedures in real-life clinical situations Complete with case studies, checklists, and study questions, this practical, didactic book is ideal as both a textbook and a reference. Students and practitioners of physical and manual therapy will find it essential for gaining the knowledge and decision-making skills to treat any musculoskeletal disorder related to posture and movement.
Author: Kat Barrett Publisher: eXtasy Books ISBN: 1487403895 Category : Fiction Languages : en Pages : 278
Book Description
Aria Bastion is aging without the power of Keir's love. Jace has become her keeper, but he can do nothing to offset the foreseeable death in her future. When nineteen-year-old sorcerer Laniar Storm walks into their lives, he may be the key to give Aria and Jace a new future. Laniar's young body holds a secret that Aria and Jace are the last to discover. Can he overcome his own insecurity to find a place in the lives of the two highest powers Jasta has ever known? When the power again calls strife into their lives, can Jace and Laniar work together to save Aria's body and mind, or will the dark claws of death sink their talons into her after all?
Author: Mukund S. Chorghade Publisher: Wiley-Interscience ISBN: 9780471398486 Category : Science Languages : en Pages : 476
Book Description
From first principles to real-world applications -- here is the first comprehensive guide to drug discovery and development Modern drug discovery and development require the collaborative efforts of specialists in a broadarray of scientific, technical, and business disciplines--from biochemistry to molecular biology, organic chemistry to medicinal chemistry, pharmacology to marketing. Yet surprisingly, until now, there were no authoritative references offering a complete, fully integrated picture of the process. The only comprehensive guide of its kind, this groundbreaking two-volume resource provides an overview of the entire sequence of operations involved in drug discovery and development--from initial conceptualization to commercialization to clinicians and medical practitioners. Volume 1: Drug Discovery describes all the steps in the discovery process, including conceptualizing a drug, creating a library of candidates for testing, screening candidates for in vitro and in vivo activity, conducting and analyzing the results of clinical trials, and modifying a drug as necessary. Volume 2: Drug Development delves into the nitty-gritty details of optimizing the synthetic route, drug manufacturing, outsourcing, and marketing--including drug coloring and delivery methods. Featuring contributions from a world-class team of experts, Drug Discovery and Development: * Features fascinating case studies, including the discovery and development of erythromycin analogs, Tagamet, and Ultiva (remifentanil) * Discusses the discovery of medications for bacterial infections, Parkinson's disease, psoriasis, peptic ulcers, atopic dermatitis, asthma, and cancer * Includes chapters on combinatorial chemistry, molecular biology-based drug discovery, genomics, and chemogenomics Drug Discovery and Development is an indispensable working resource for industrialchemists, biologists, biochemists, and executives who work in the pharmaceutical industry.
Author: Lester Grinspoon
Author: Lester Grinspoon
Author: Miriam Beloglovsky
Author: Chris Holland
Author: Congressional Budget Office
Author: Kavi Kishor P.B.
Author: Michael J. Klepper
Author: Jochen Schomacher
Author: Kat Barrett
Author: Kevin Huo
Author: Mukund S. Chorghade