Commissioning of the Treatment Planning System RayStation at the Heidelberg Ion-Beam Therapy Center PDF Download

Author: Benedikt Kopp
Publisher:
ISBN:
Category :
Languages : en
Pages :

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The Heidelberg Ion-Beam Therapy Center (HIT) uses the Raster Scan technique for proton and carbon ions. The treatment planning system (TPS) RayStation, Raysearch Laboratories, will be integrated into the application system IONTRIS, Siemens Healthineers.As TPS commissioning for proton and carbon ions various cases of target volumes were optimized with the clinical TPS Syngo RT Planning, Siemens Healthineers, using a Pencil Beam (PB) algorithm. Dose distributions rising from simple geometries like cubic volumes in water to complex cases like anthropomorphic Rando Alderson head phantom and double-wedge phantom were recalculated in RayStation using a PB algorithm for Carbons and Monte Carlo (MC) for Protons. RayStation dose distributions were compared with syngo TPS calculations and to measurements with a 24 Pin-Point chamber array in a water phantom and for complex geometries with the 2D array Octavius1000SRS, both PTW.For Protons both TPS were comparable for simple geometries. The RayStation MC algorithm better describes the lateral spread of the proton beam passing a range modulator and an air gap of 20 cm. For complex geometries, including cases with lateral inhomogeneities or oblique entrance, the RayStation MC shows better agreement with the measurements. The carbon PB calculation is on the same level of precision as the Syngo TPS for all geometries.Still based on preliminary basis data, the RayStation dose calculation yields excellent results. We are looking forward to integrating RayStation into clinical routine and making use of its powerful tools.

Author: Junetsu Mizoe
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ISBN:
Category :
Languages : en
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Purpose] To ensure safe operation of the new carbon ion therapy system Osaka-HIMAK (Heavy-Ion Medical Accelerator in Kansai). [Methods] Osaka Heavy-ion Therapy Center has three treatment rooms. Two of them (room 2 and 3) have horizontal and vertical ports, and another one (room 1) has horizontal and 45-degree ports. The two ports in the same room share a nozzle, which includes dose monitors, range shifters and ripple filters, and moves between the ports rotating around the isocenter. The respiratory-gated irradiation system is introduced in the room 1 and 2, and in-room CT will be installed in the room 2. The clinical commissioning had been done for the patient positioning system, the respiratory-gated irradiation system (and method), the beam delivery (raster scanning) system, and the treatment planning system (RayStation Doctor for delineation and evaluation, and VQA for planning). We adopt the mixed-beam model as the biological model for treatment planning, and the so-called Schneideru2019s method to derive the conversion table between CT value and the relative stopping power ratio.[Results] The clinical commissioning of the room 3 had been completed by 15 October 2018, and the first treatment was carried out in 16 October. The treatment in the room 1 and 2 were also started sequentially after the clinical commissioning of each room was completed.[Conclusion] The eleventh carbon ion therapy facility had safely started the treatment in October 2018.

Author: Jui Wan
Publisher:
ISBN:
Category :
Languages : en
Pages : 76

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RayStation, a new treatment planning system (TPS), was purchased and recently commissioned for clinical use by the institution. As part of the commissioning process, an accurate model of the TrueBeam linear accelerator was made prior to clinical acceptances. Data collection, importing measurements, beam modeling, point dose verifications and clinical plan comparisons are procedures that must be done in order to complete the commissioning of photon and electron energies. During the beam modeling process, various parameters were modified to achieve close matches between the computed and measured PDD curves, as well as measured and computed beam profiles. The tolerance objectives were to have computed data deviating from the measured data within the 2% in fall-off regions, 3% tolerance within in-field and out-of-field regions, and 10% tolerance in build-up regions and penumbra regions [1] . The dosimetric validation procedure followed. Point dose measurements were completed using both the ArcCHECK phantom and the water tank. The majority of the results met the set criteria except for some measurements blocked by MLC leaves or jaws when taken adjacent to the edge of fields. To further confirm the goodness of modeled beams, clinical treatment plans developed with the previously clinically commissioned Pinnacle TPS and imported into the RayStation TPS to generate new plans with same beam arrangements and control points and used as comparisons. After clinical commissioning was completed for RayStation software, a feasibility of using FFF beams to deliver identical or superior beam profile provided by conventional flattened beams of the same energy was investigated. The objective of this research was to show that through sliding window treatment planning, one can create optimized plans and hence no longer the technology of flattening filter is required in modern linear accelerators. To explore this topic, a two stage analysis was carried out. First, delivering doses in a water cube with 10 × 10 to 30 × 30 cm2 open-field 6 MV flattened beams and also create 0.1cm thick square plane structures to be used when undergo the optimization process with 6 FFF beams. Then scaling doses to prescribe 100 cGy at the center of the plane for comparison purpose. The overall uniformity of line profile for FFF beams across the CAX at 10 cm depth showed 1% to 2% superior to flattened beams. For the clinical treatment plans comparison, ten patients were selected with five head and neck cancer plans as well as five lung and mediastinum cancer plans. Original plans were all completed with 6 MV flattened beams and approved by radiation oncologists. New plans were accomplished with 6 FFF beams and same coverages of PTVs were achieved. Most of average mean doses to critical structures and normal tissue volumes receiving 5%, 10%, 20% and 30% of the prescription dose were reduced with FFF plans with slightly increased average max doses.

Author: Serban Morcovescu
Publisher:
ISBN:
Category : Electron beams
Languages : en
Pages : 380

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Author: Yoshiro Ieko
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Languages : en
Pages :

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Construction of seventh carbon-ion therapy facility in Japan, East Japan Heavy Ion Center, Faculty of Medicine, Yamagata University, is near completion. The building is 45 m u00d7 45 m u00d7 27 m cubic design, smallest facility in the world, and connects directly to general hospital. A main synchrotron accelerator (a maximum energy of 430 MeV/u) with newly designed dipole magnets is located on the basement floor. There are two treatment rooms, horizontal and 360u02da rotating gantry, on the 2nd floor. Rotating gantry is even smaller than NIRS gantry using the superconducting technique and shortened scanning system. We chose RayStation (RaySearch Laboratories AB) as the treatment planning system which has very fast dose calculation engine to accurately calculate dose. In 2019, building construction and system installation will be completed, and acceptance testing and clinical commissioning will begin. After the commissioning work, first patient will be treated in spring 2020.

Author: Andrea Mairani
Publisher:
ISBN:
Category :
Languages : en
Pages :

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Since 2009, over 5000 patients have been treated with proton (1H) and carbon (12C) ion beams at the Heidelberg Ion Therapy Center (HIT). By 2020, HIT will begin the first clinical raster-scanning particle therapy program using helium (4He) ions, which exhibit favorable biophysical properties intermediate of clinically used light and heavy ions. Today, a commercial treatment planning system (TPS) for 4He ions does not exist. This calls for an extensive development, testing and verification of a TPS for 4He ions, exploring both physical and biological dose models.This year, a GPU-based dose computation code for particle therapy (FRoG) was developed at HIT. Due to its parallelized computation scheme, sophisticated beam model and outstanding performance in conditions with anatomical complexity, FRoG performs forward dose calculations within minutes (in contrast to full simulation with hour-long runtimes) in excellent agreement with the clinical gold standard Monte Carlo simulations and measurements. Recent efforts focus on dose optimization (both physical and biological) for raster-scanning 4He ions beam therapy. A fully functional TPS within the FRoG framework will be devised and clinically integrated for 4He ion beams.Furthermore, biological phenomena of 4He ion beams remains poorly explored since the shutdown of clinical trials at the Lawrence Berkely National Laboratory in the early 1990u2019s. Potential biophysical and mechanistic approaches to modeling the relative biological effectives (RBE) in the clinic are under investigation in preparations for the first in-man treatment with raster-scanning 4He ion beams.

Author: International Atomic Energy Agency
Publisher:
ISBN: 9789201005083
Category : Psychology
Languages : en
Pages : 67

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This publication is intended as a guide for the clinical commissioning of radiotherapy treatment planning systems (RTPSs) and provides a simple protocol for these tasks. The procedures for clinical commissioning tests cover typical treatment techniques used in the radiotherapy hospitals and are based on the use of a specific phantom. The purpose of this testing is twofold. Firstly, the tests will provide an educational opportunity for the user to become familiar with the operation of the RTPS. Secondly, the tests will demonstrate to the user that the logistic chain starting from CT scanning, anatomic modelling, treatment planning and MU calculation is operable and leads to the desired results with sufficient accuracy.

Author: IAEA.
Publisher:
ISBN: 9789204006162
Category :
Languages : ru
Pages : 277

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Book Description
This publication is intended as a guide for the clinical commissioning of radiotherapy treatment planning systems (RTPSs) and provides a simple protocol for these tasks. The procedures for clinical commissioning tests cover typical treatment techniques used in radiotherapy hospitals and are based on the use of a specific phantom. The purpose of this testing is twofold. Firstly, the tests will provide an educational opportunity for the user to become familiar with the operation of the RTPS. Secondly, the tests will demonstrate to the user that the logistic chain starting from computed tomography (CT) scanning, anatomic modelling, treatment planning and monitor unit/ time (MU) calculation is operable for typical treatment techniques and leads to the desired results with sufficient accuracy.

Author: Stewart Mein
Publisher:
ISBN:
Category :
Languages : en
Pages :

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The Danish Centre for Particle Therapy (DCPT) will treat its first patient soon. To facilitate a rapid and robust dose calculation that also functions as an independent secondary dose calculation, Fast dose Recalculation on GPU (FRoG), has been implemented at DCPT. FRoG, which has been developed in-house at the Heidelberg Ion Therapy Center (HIT) and the Centro Nazionale di Adroterapia Oncologica (CNAO), has previously shown excellent agreement with both gold standard Monte Carlo (MC) simulations and measurements due to its superior beam splitting algorithm and triple Gaussian beam model. CNAO and HIT are both synchrotron-based facilities whereas the DCPT uses a cyclotron and beam delivery provided by Varian Medical Systems. Minor adjustments in the codebase had to be made to enable FRoG at DCPT. Furthermore, DCPTs beam shape and integrated depth dose distributions (iDDDs) were modelled in FLUKA MC to generate LET and iDDD distributions for FRoG base data. Figure 1 shows FLUKA-generated iDDDs against measurements at DCPT, demonstrating excellent agreement. Continuous energy selection used at DCPT was implemented by means of Bragg Peak interpolation between commissioned iDDDs. Initial validation studies show good agreement between measurements and FRoG predictions. Extensive validations against measurements and the clinically used treatment planning system of DCPT (Eclipse, Varian Medical Systems, Palo Alto, CA, USA) are currently underway. With the FRoG framework, comprehensive large-scale studies on plan robustness, dose delivery and biological effect can be performed at DCPT within a clinically reasonable time-frame due to FRoGs extensive GPU utilization and flexible dose engine.

Author: International Atomic Energy Agency
Publisher: Technical Reports Series
ISBN:
Category : Business & Economics
Languages : en
Pages : 318

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Book Description
The relatively low cost of equipment has made treatment planning systems (TPSs) widely available in industrialised and developing countries. This report is intended to support hospitals in developing procedures for the commissioning and quality assurance of computerised TPSs, covering four key issues relating to education, verification, documentation and communication.