Combination therapy in MS PDF Download

Author: Yvette Corinne Zwick
Publisher: Schattauer Verlag
ISBN: 9783794524365
Category :
Languages : en
Pages : 60

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Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309072859
Category : Medical
Languages : en
Pages : 457

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Book Description
Multiple sclerosis is a chronic and often disabling disease of the nervous system, affecting about 1 million people worldwide. Even though it has been known for over a hundred years, no cause or cure has yet been discovered-but now there is hope. New therapies have been shown to slow the disease progress in some patients, and the pace of discoveries about the cellular machinery of the brain and spinal cord has accelerated. This book presents a comprehensive overview of multiple sclerosis today, as researchers seek to understand its processes, develop therapies that will slow or halt the disease and perhaps repair damage, offer relief for specific symptoms, and improve the abilities of MS patients to function in their daily lives. The panel reviews existing knowledge and identifies key research questions, focusing on: Research strategies that have the greatest potential to understand the biological mechanisms of recovery and to translate findings into specific strategies for therapy. How people adapt to MS and the research needed to improve the lives of people with MS. Management of disease symptoms (cognitive impairment, depression, spasticity, vision problems, and others). The committee also discusses ways to build and financially support the MS research enterprise, including a look at challenges inherent in designing clinical trials. This book will be important to MS researchers, research funders, health care advocates for MS research and treatment, and interested patients and their families.

Author: Nicole N. M. Trager
Publisher:
ISBN:
Category :
Languages : en
Pages : 137

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Book Description

Author: Ian S. Zagon
Publisher:
ISBN: 9780994438133
Category :
Languages : en
Pages : 137

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Book Description

Author: Michael Olek
Publisher: Springer Science & Business Media
ISBN: 1592598552
Category : Medical
Languages : en
Pages : 253

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Book Description
A synthesis of current concepts about the evaluation, treatment, and future directions in MS. On the evaluation side, the authors review the use of MRI, magnetic resonance spectroscopy, functional MRI, and three-dimensional MRI, and consider the rapidly developing body of pathologic information they have yielded. On the treatment side, the focus is on recently approved medications (Novantrone), new indications for medications (CHAMPS Trial), medications in development (Oral Interferon Tau, Oral Copaxone, and Oral Cellcept), immunosuppressive therapy for both progressive disease and symptomatic therapy; the current medications for treating relapsing-remitting MS (Avonex, Betaseron, and Copaxone) are also discussed. For future directions, the authors present the current best thinking, as well as the latest discoveries in immunology relating to MS, including groundbreaking B-cell research and its applications to specific immunotherapies, and the use of immune markers for tracking the disease.

Author: Eli Minkoff
Publisher: CRC Press
ISBN: 0203012054
Category : Medical
Languages : en
Pages : 928

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Book Description
Since the publication of the previous edition of this volume, there has been substantial progress in a number of areas of multiple sclerosis (MS) research. Although immunosuppressive treatments continue to be developed and refined, more targeted immunomodulatory therapies are surfacing as we learn more about how the immune system works in health an

Author: Richard Rudick
Publisher: CRC Press
ISBN: 9780415805827
Category : Medical
Languages : en
Pages : 598

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Book Description
This textbook examines the most important aspects of multiple sclerosis that impact on clinical trial design, on the development of new disease therapies and on patient care. The international team of contributors discuss the clinical course of multiple sclerosis, its clinical heterogeneity, the presence of subclinical disease activity which occurs during the early stages of the disease. Multiple sclerosis presents clinical challenges: from unexpected and irregular relapses to profressive deterioration.

Author: Richard A. Rudick
Publisher: CRC Press
ISBN: 9781841842264
Category : Medical
Languages : en
Pages : 784

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Book Description
This revised textbook examines the most important aspects of multiple sclerosis that impact on clinical trial design, on the development of new disease therapies, and, most importantly, on patient care. An international team of contributors discusses the clinical course of multiple sclerosis, its clinical heterogeneity, and the presence of subclinical disease activity which occurs during the early stages of the disease. There have been substantial advances in the field since the first edition was published in 1999. There are new chapters on functional imaging, the issues involved in long-term follow-up studies, cyclophosphamide, sex hormones and pregnancy-related factors, complementary and alternative treatments, management of cognitive impairment, treatment of pain, and rehabilitative approaches. Chapters on MS pathogenesis, imaging, the interferons, glatiramer acetate, mitoxantrone, IVIg, plasma exchange, stem cell transplantation, combination therapies, and newly-emerging treatments have been updated. This book is essential for any clinician who works with MS patients.

Author: Richard A. Rudick
Publisher: CRC Press
ISBN: 9781135414023
Category : Medical
Languages : en
Pages : 784

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Book Description
This revised textbook examines the most important aspects of multiple sclerosis that impact on clinical trial design, on the development of new disease therapies, and, most importantly, on patient care. An international team of contributors discusses the clinical course of multiple sclerosis, its clinical heterogeneity, and the presence of subclinical disease activity which occurs during the early stages of the disease. There have been substantial advances in the field since the first edition was published in 1999. There are new chapters on functional imaging, the issues involved in long-term follow-up studies, cyclophosphamide, sex hormones and pregnancy-related factors, complementary and alternative treatments, management of cognitive impairment, treatment of pain, and rehabilitative approaches. Chapters on MS pathogenesis, imaging, the interferons, glatiramer acetate, mitoxantrone, IVIg, plasma exchange, stem cell transplantation, combination therapies, and newly-emerging treatments have been updated. This book is essential for any clinician who works with MS patients.

Author: Jonathan Howard, MD
Publisher: Springer Publishing Company
ISBN: 0826177476
Category : Health & Fitness
Languages : en
Pages : 124

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Book Description
If you or a loved one has been diagnosed with multiple sclerosis, this book should be your first stop. Written in easy-to-understand language by an MS specialist, this guide explores the questions that patients and their families typically ask—from disease basics, to treatment options, managing relapses, and lifestyle concerns, including diet and working. Whether newly diagnosed or coping with the unpredictable day-to-day, this valuable reference will arm you with the latest information. Designed to be a thorough, yet concise summary of all aspects of MS, the book simplifies complex medical topics and is based on the latest science. For patients at any stage and the people who support them, Multiple Sclerosis: Questions and Answers for Patients and Loved Ones provides the answers you need to understand this disease, its challenges, and the medical treatments and other tools now available for managing it successfully. Key Features: Complete guide with straightforward answers to the most frequently asked questions by MS patients Up-to-date information on treatment options, including the benefits and drawbacks of new MS medications and who should be taking them Addresses special topics, such as pregnancy in combination with MS treatments and working after diagnosis Presents an overview of symptoms with tips on how to combat them Offers useful advice about symptom management and lifestyle changes to meet the physical and emotional challenges MS brings