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Author: Mauro Monteiro Correia Publisher: Springer Nature ISBN: 3030254860 Category : Medical Languages : en Pages : 597
Book Description
Colorectal cancer is the third most commonly diagnosed condition in oncology, affecting around 1.23 million individuals per year, according to recent statistics. Of these patients, about 50% will develop liver metastases and approximately 20% will present a stage IV disease at diagnosis. These statistics make colorectal liver metastases (CLM) an issue of major importance in current oncology. The area of CLM is subject to great and continuous advances, as its pathophysiologic mechanisms are better understood and more therapeutic and surgical options are developed. Consequently, all professionals involved with the diagnosis, treatment and follow up of CLM should be kept up to date with the latest advances on the field, to provide high standard medical care to their patients. This book is designed to present the state-of-the-art in CLM management and, in doing so, to review the current evidence on CLM, discussing all important topics in the field. Coverage is broad and comprehensive, encompassing introductory topics (history, definitions, epidemiology, etc.), basic science subjects (molecular biology, genetics, dissemination process, etc.) and practical clinical topics (tumor behavior, diagnosis, drug therapy, radiation therapy, surgery, ablation, multidisciplinary teams, etc.). Although comprehensive on the coverage and selection of topics, each chapter is concise and objective, dissecting topics in a practical and direct format. Evidences and recommendations are included. Chapters display a brief introduction of the common knowledge, go straight to the detailed revision of the most recent years of the literature, and end with practical closing observations. This book is a tool for professionals (general and cancer surgeons, HPB surgeons, clinical oncologists, gastroenterologists and medical residents) and interns who search for a qualified and reader friendly revision on topics concerning Colorectal Cancer Liver Metastases.
Author: Mauro Monteiro Correia Publisher: Springer Nature ISBN: 3030254860 Category : Medical Languages : en Pages : 597
Book Description
Colorectal cancer is the third most commonly diagnosed condition in oncology, affecting around 1.23 million individuals per year, according to recent statistics. Of these patients, about 50% will develop liver metastases and approximately 20% will present a stage IV disease at diagnosis. These statistics make colorectal liver metastases (CLM) an issue of major importance in current oncology. The area of CLM is subject to great and continuous advances, as its pathophysiologic mechanisms are better understood and more therapeutic and surgical options are developed. Consequently, all professionals involved with the diagnosis, treatment and follow up of CLM should be kept up to date with the latest advances on the field, to provide high standard medical care to their patients. This book is designed to present the state-of-the-art in CLM management and, in doing so, to review the current evidence on CLM, discussing all important topics in the field. Coverage is broad and comprehensive, encompassing introductory topics (history, definitions, epidemiology, etc.), basic science subjects (molecular biology, genetics, dissemination process, etc.) and practical clinical topics (tumor behavior, diagnosis, drug therapy, radiation therapy, surgery, ablation, multidisciplinary teams, etc.). Although comprehensive on the coverage and selection of topics, each chapter is concise and objective, dissecting topics in a practical and direct format. Evidences and recommendations are included. Chapters display a brief introduction of the common knowledge, go straight to the detailed revision of the most recent years of the literature, and end with practical closing observations. This book is a tool for professionals (general and cancer surgeons, HPB surgeons, clinical oncologists, gastroenterologists and medical residents) and interns who search for a qualified and reader friendly revision on topics concerning Colorectal Cancer Liver Metastases.
Author: U. Metzger Publisher: Springer Science & Business Media ISBN: 3642824323 Category : Medical Languages : en Pages : 170
Book Description
One reason for failure to cure solid tumors by surgery appears to be the impossibility of controlling metastases that are present but latent at the time of operation. This failure is a common clinical experience with aggressive neoplasms. but it is not always appreciated in tumors with longer survival times. e. g .• breast and colon cancer. In addition. recent evidence indicates that after resection of a primary tumor micrometas tases from it might be enhanced by suppression of immune and reticu loendothelial functions of the host. Other factors, such as increase of coagulability and stress in the perioperative period, can also promote tumor growth. The development of new metastases might be facilitated by cells forced into the circulation during operative manipulations. Such events could be important for the outcome of treatment and it is suggested that preventive measures should be directed to this systemic component of solid tumors. Radical surgery can reduce the number of tumor cells to a subclinical 3 6 stage (10 to 10 cells) in which chemotherapy might be more effective than in advanced stages. Chemotherapy, on the other hand, might aggravate the surgical morbidity by influencing the wound healing pro cess, by decreasing the immune response, and/or by toxicity to the bone marrow and to the gastrointestinal tract, for example.
Author: Nicole Beauchemin Publisher: Springer ISBN: 9789400732933 Category : Medical Languages : en Pages : 416
Book Description
Colorectal cancer is the third most common cancer worldwide, and in many parts of the western world, it is the second leading cause of cancer-related deaths. This book covers colon cancer metastasis from the most fundamental aspects to clinical practice. Major topics include physiopathology, genetic and epigenetic controls, cancer initiating cells, epithelial-mesenchymal transition, growth factors and signalling, cell adhesion, natures of liver metastasis, angiogenesis and lymphangiogenesis, inflammatory response, prognostic markers, sentinel node and staging, and finally diagnosis and treatment. Each chapter has been contributed by leaders in the field. A key feature is that it connects with a large readership including students, fundamentalists and clinicians. Another specific feature of the book is that the chapters are written in a didactic and illustrative fashion. These characteristics coupled with the choice of the topics and authors, makes this book a reference in the field. It represents an essential acquisition for medical libraries, clinicians as well as medical and graduate students.
Author: Robert C. Bast, Jr. Publisher: John Wiley & Sons ISBN: 111900084X Category : Medical Languages : en Pages : 2004
Book Description
Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates
Author: Omer Engin Publisher: Springer Nature ISBN: 3030572730 Category : Medical Languages : en Pages : 724
Book Description
This thoroughly revised and extended second edition of the book clearly explains the nature of colon polyps and their relationship to colorectal cancer in light of new developments. It discusses in detail new topics, including polyp development, risk factors and prevention measures, and also describes surgical, medical oncology and radiotherapy treatments of colon cancer. In cases of advanced colon cancer, it clearly demonstrates how to perform surgical interventions in the presence of urinary tract metastases and gynecologic organ metastases. The book also includes chapters on medical treatment and radiotherapy in distant metastases of colorectal cancer. Further, it presents resection of liver metastases and transplantation options. Carefully examining the risk factors, and the treatment of colon cancer from the early to the advanced stages, the book is invaluable not only for medical specialists and students, but also for general readers and patients.
Author: Frances C. Wright Publisher: Springer Nature ISBN: 3030483630 Category : Medical Languages : en Pages : 526
Book Description
This third edition manual provides a comprehensive, insightful, evidenced-based review of general surgical oncology and serves as a valuable resource for general surgeons in training, practicing general surgeons, and surgical oncologists. The volume describes a multidisciplinary approach that integrates clinical, radiologic, and pathologic data in formulating practical clinical management, and offers a practical approach to the most common situations when treating cancer patients. Each chapter focuses on an individual malignancy and describes the presentation of the malignancy, integrated management based on stage, landmark trials, and suggestions for who to discuss at multidisciplinary cancer conferences. Multiple tables in each chapter provide a concise yet comprehensive summary of the current status of the field. Clinical “pearls” or tips and tricks from high volume surgeons at the University of Toronto are also discussed. The third edition of the Surgical Oncology Manual will serve as a critical resource for general surgeons in training and practicing surgeons dealing with this challenging field.
Author: Yong Du Publisher: Springer ISBN: 3319548379 Category : Medical Languages : en Pages : 89
Book Description
This book is a pocket guide to the science and practice of PET/CT imaging of colorectal malignancies. The role of PET/CT in these patients, the characteristic PET/CT findings, and the advantages and limitations of this hybrid modality are all clearly described. In addition, information is provided on clinical presentation, diagnosis, staging, pathology, management, and radiological imaging. The book is published within the Springer series Clinicians' Guides to Radionuclide Hybrid Imaging, which is aimed at nuclear medicine/radiology residents and physicians, referring clinicians, radiographers/technologists, and nurses who routinely work in nuclear medicine and participate in multidisciplinary meetings. Compiled under the auspices of the British Nuclear Medicine Society, the series is the joint work of many colleagues and professionals worldwide who share a common vision and purpose in promoting and supporting nuclear medicine as an important imaging specialty for the diagnosis and management of oncological and non-oncological conditions.
Author: Tim Cross Publisher: Springer ISBN: 3319922165 Category : Medical Languages : en Pages : 312
Book Description
This book explores in detail the primary liver cancers of hepatocellular carcinoma and cholangiocarcinoma examining the pathogenesis of disease along with diagnosis and current management options together with exploration of future treatment strategies and areas of controversy. Furthermore, the book highlights management of the common secondary malignancies and touches on benign liver tumours and how to best manage these. Written in a clear and didactic style, this volume includes summaries of the key learning points and questions so that the reader can gauge their knowledge and understanding. This book is aimed to broaden the knowledge base of primary care physicians, general physicians along with specialists in hepatology, oncology and hepato-biliary surgery
Author: Mauro Monteiro Correia
Author: Mauro Monteiro Correia
Author: U. Metzger
Author: Nicole Beauchemin
Author: Robert C. Bast, Jr.
Author: Omer Engin
Author: Frances C. Wright
Author: Diana B. Petitti
Author: Yong Du
Author: Gerhard J. Müller
Author: Tim Cross