CNS Recovery after Structural and/or Physiological/Psychological Damage

CNS Recovery after Structural and/or Physiological/Psychological Damage PDF Author: Marie Moftah
Publisher: Frontiers Media SA
ISBN: 2889450406
Category :
Languages : en
Pages : 109

Book Description
There is an assumption that environmental threats could cause important damages in central nervous system. As a consequence, several forms of brain structural plasticity could be affected. The environmentally mediated risks include generally physical (such as brain and spinal cord injury) and psychological / psychosocial influences (e.g. stress). In general, the response of the organism to these environmental challenges passes via adaptive responses to maintain homeostasis or functional recovery. These processes engage the immune system, the autonomic nervous system (ANS) besides the hypothalamo-hypophyseo-adrenal (HPA) axis via specific hormones, neurotransmitters, neuropeptides and other factors which participate, in several cases, in structural remodeling in particular brain areas. To what extent a brain and / or spinal cord recovery after structural and / or physiological / psychological damage could occur and by which mechanisms, this is the goal of this Research Topic. It concerns neurogenesis, growth factors and their receptors, and morphological plasticity. On the other hand, it is well known that stress experienced an obvious impact on many behavioral and physiological aspects. Thus, environmental stress affects neuroendocrine structure and function and hence such aspects may influence brain development. Knowing normal organization of neurotensin receptors’ system during postnatal development in human infant will help understanding the dysfunction of this neuropetidergic system in “sudden infant syndrome” victims. Stress could affect also other non-neuroendocrine regions and systems. GABA is one of the classical neurotransmitter sensitive to stress either when applied acutely or repetitively as well as its receptor GABAA. Furthermore, the modulation of this receptor complex notably by neurosteroids is also affected by acute stress. These steroids seem to play a role in the resilience retained by the stressed brain. Their modulatory role will be studied in the context of chronic stress in rats. Finally, one of the major impacts of stress besides changes in psychological behavior is the alteration of food intake control causing in final eating disorders. This alteration is the result of changes occurring in activity of brain regions involved in stress responses (principally HPA and ANS) and which are also involved in food intake control. The series of studies presented here, will try to explain how different stress paradigms affect this function and the eventual interactions of glucocorticoids with orexigenic (neuropetide Y: NPY/Agouti Related Peptide: AgRP) and anorexigenic peptides (Pre-opiomelanocortin peptide: POMC/Cocaine Amphetamine regulatory Transcript peptide: CART).

Recovery from Brain Damage

Recovery from Brain Damage PDF Author: Stanley Finger
Publisher: Springer Science & Business Media
ISBN: 1461577233
Category : Psychology
Languages : en
Pages : 429

Book Description
It has long been recognized that damage to the mammalian central nervous system may be followed by behavioral recovery, but only re cently has close attention been directed to specific factors which may enhance or retard restitution. This is evident in the rapidly growing number of journal articles and scientific paper sessions dealing with "recovery of function," as well as in the publicity given by the popular press to some of the findings in this field. The present text seeks to examine the foundations of brain lesion research, to review recent material on a number of factors which ap pear to contribute to recovery after brain damage, and to present mod els which have been proposed to account for these effects. In order to best accomplish these goals, a number of key workers in these areas were asked to examine and describe research literatures dealing with specific problems or methodological manipulations associated with brain damage and behavior, using their own experiments and those of others to illustrate important points. In addition, significant interpre tive and theoretical issues were to be evaluated in each chapter.

Translational Research in Traumatic Brain Injury

Translational Research in Traumatic Brain Injury PDF Author: Daniel Laskowitz
Publisher: CRC Press
ISBN: 1498766579
Category : Medical
Languages : en
Pages : 388

Book Description
Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the developme

Physiological Psychology

Physiological Psychology PDF Author: Prof. Dr. Bilal Semih Bozdemir
Publisher: Prof. Dr. Bilal Semih Bozdemir
ISBN:
Category : Psychology
Languages : en
Pages : 489

Book Description
Physiological Psychology: The Intersection of Mind and Body What is Physiological Psychology? The Brain: Structure and Function The Central Nervous System (CNS) The Peripheral Nervous System (PNS) The Endocrine System Sensory Perception Vision: The Eyes and the Visual Cortex Audition: The Ears and the Auditory Cortex Somatosensation: Touch, Proprioception, and the Somatosensory Cortex Gustation: Taste and the Gustatory Cortex Olfaction: Smell and the Olfactory Cortex Motor Control and the Motor Cortex Motivation and the Limbic System Emotion and the Limbic System Sleep and the Circadian Rhythm Learning and Memory Neuroplasticity: The Adaptable Brain Stress and the Physiological Response Mental Disorders and the Brain Psychoactive Drugs and the Brain Neuroimaging Techniques Ethical Considerations in Physiological Psychology Careers in Physiological Psychology The Future of Physiological Psychology Integrating Mind and Body: The Holistic Approach Conclusion: The Importance of Physiological Psychology

Research Awards Index

Research Awards Index PDF Author:
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 874

Book Description


Research Grants Index

Research Grants Index PDF Author: National Institutes of Health (U.S.). Division of Research Grants
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1212

Book Description


Preoperative Events

Preoperative Events PDF Author: Jay Schulkin
Publisher: Psychology Press
ISBN: 1317786106
Category : Psychology
Languages : en
Pages : 368

Book Description
Preoperative Events switches the focus from post-operative rehabilitation to preoperative experiences and personal histories to lessen the consequences of brain damage. These papers document the relationship between preoperative experience and postoperative performance and discuss a variety of protective preoperative experiences that can ameliorate the deleterious effects of brain damage.

Pituitary Adenylate Cyclase-Activating Polypeptide

Pituitary Adenylate Cyclase-Activating Polypeptide PDF Author: Hubert Vaudry
Publisher: Springer Science & Business Media
ISBN: 9781402073069
Category : Medical
Languages : en
Pages : 432

Book Description
Pituitary Adenylate Cyclase-Activating Polypeptide is the first volume to be written on the neuropeptide PACAP. It covers all domains of PACAP from molecular and cellular aspects to physiological activities and promises for new therapeutic strategies. Pituitary Adenylate Cyclase-Activating Polypeptide is the twentieth volume published in the Endocrine Updates book series under the Series Editorship of Shlomo Melmed, MD.

Cognitive Rehabilitation

Cognitive Rehabilitation PDF Author: Lance E. Trexler
Publisher: Springer Science & Business Media
ISBN: 1468442503
Category : Psychology
Languages : en
Pages : 282

Book Description
The present volume has come about through an awareness of the absence of any cohesive and substantive source on the treatment of cognitive dysfunction following brain insult. I initiated the devel opment of our annual symposium Models and Techniques of Cognitive Rehabilitation, on which the present volume is based, so as to educate myself, as well as others, about the state of the art in modifying cognitive processes in the brain, injured. I became aware of the need for interventive strategies for the brain, injured while a graduate student. Brain functions had, for a long time, always fascinated me, but from an academic perspective. I was confronted with the clinical consequences of brain injury while administering batteries of neuro psychological tests, and this experience added another dimension to my interest in brain functions. I felt grossly inadequate because I was able to rather eloquently describe changes in brain-behavior relations with neuropsychological tests, but could only generate re commendations based solely on the use of compensatory strategies and occasionally on some unfounded, and probably naive, remedial guess. A literature search at this time yielded devastating, little informa tion. The next several years were characterized by a pseudo-obsession, occurring at times without total awareness, with methods and tech niques which might alter impaired brain-behavior relations. Completing graduate school, however, required that these thoughts take a secondary position relative to more typical graduate student thoughts.

Federal Register

Federal Register PDF Author:
Publisher:
ISBN:
Category : Administrative law
Languages : en
Pages : 1056

Book Description