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Author: M. Lambert Publisher: Springer Science & Business Media ISBN: 1468413279 Category : Science Languages : en Pages : 654
Book Description
This volume contains edited contributions from the speakers at the NATO Advanced Research Workshop on "DNA Repair Mechanisms and Their Biological Implications in Mammalian Cells" held October 1-6, 1988, at the Abbaye Royale de Fontevraud, Fontevraud France. The meeting was dedicated to Paul Howard-Flanders (Yale University, New Haven, CT. , 1919-1988), whose seminal con tributions to the DNA repair field include the cO-discovery of the excision repair pathway, the elucidation of post-repli cation repair in E. coli, the isolation of the lexA and recC mutants, and his extensive work on the enzymology of RecA. A plethora of recent developments in DNA repair mechan isms and related processes in mammalian cells have advanced our understanding of this field in a number of different areas and have given new emphasis to the ways these systems both resemble DNA repair processes in other groups of organisms in some respects yet are strikingly different from them in others. Within the past decade there have been a number of international conferences on DNA damage and repair mechanisms but none has been focused on these processes in mammalian cells.
Author: M. Lambert Publisher: Springer Science & Business Media ISBN: 1468413279 Category : Science Languages : en Pages : 654
Book Description
This volume contains edited contributions from the speakers at the NATO Advanced Research Workshop on "DNA Repair Mechanisms and Their Biological Implications in Mammalian Cells" held October 1-6, 1988, at the Abbaye Royale de Fontevraud, Fontevraud France. The meeting was dedicated to Paul Howard-Flanders (Yale University, New Haven, CT. , 1919-1988), whose seminal con tributions to the DNA repair field include the cO-discovery of the excision repair pathway, the elucidation of post-repli cation repair in E. coli, the isolation of the lexA and recC mutants, and his extensive work on the enzymology of RecA. A plethora of recent developments in DNA repair mechan isms and related processes in mammalian cells have advanced our understanding of this field in a number of different areas and have given new emphasis to the ways these systems both resemble DNA repair processes in other groups of organisms in some respects yet are strikingly different from them in others. Within the past decade there have been a number of international conferences on DNA damage and repair mechanisms but none has been focused on these processes in mammalian cells.
Author: Jac A. Nickoloff Publisher: Springer Science & Business Media ISBN: 1592590950 Category : Science Languages : en Pages : 417
Book Description
Jac A. Nickoloff and Merl F. Hoekstra update and expand their two earlier acclaimed volumes (Vol. I: DNA Repair in Prokaryotes and Lower Eukaryotes and Vol. II: DNA Repair in Higher Eurkaryotes) with cutting-edge reviews by leading authorities of primary experimental findings about DNA repair processes in cancer biology. The reviews cover a wide range of topics from viruses and prokaryotes to higher eukaryotes, and include several new topics, among them the role of recombination in replication of damaged DNA, X-ray crystallographic analysis of DNA repair protein structures, DNA repair proteins and teleomere function, and the roles of BRCA1 and BRCA2 in DNA repair. Authoritative and up-to-date, DNA Damage and Repair, Vol. III: Advances from Phage to Humans surveys the rapidly moving research in DNA damage and repair, and explains the important functional relationships among different DNA repair pathways and the relationship between DNA repair pathways, cancer etiology, and cancer therapies.
Author: A. Castellani Publisher: Springer Science & Business Media ISBN: 1475750161 Category : Science Languages : en Pages : 377
Book Description
The First International Congress on DNA Damage and Repair was held in Rome, Italy, July 12-17, 1987. It was organized by the Italian Com mission for Nuclear Alternative Energy Sources. The subject of DNA damage and repair involves almost all the fields ofbidogical sciences. Some of the more prominent ones include carcino genesis, photobiology, radiation biology, aging, enzymology, genetics, and molecular biology. These individual fields have their own interna tional meetings and although the meetings often have sessions devoted to DNA repair, they do not bring together a wide diversity of international workers in the field to exchange ideas. The purpose of the Congress was to facilitate such an exchange among scientists representing many fields of endeavor and many countries. The 37 manuscripts in this volume, presented by the invited spea kers during the four and half days of the Congress, encompass the field of DNA damage and repair. They cover biological systems ranging from mo lecules to humans and deal with damages and repair after treatment of cells with various types of radiations, chemicals, and exogenous and en dogenous oxidative damages. The Congress and its Proceedings are dedicated to two international leaders in the field of DNA damage and repair, Alexander Hollaender of the United States and Adriano Buzzati Traverso of Italy. Hollaender, who died in December 1986, was one of the first investigators to recognize the damage to DNA was important in cell killing and mutagenesis. His early work indicated that cells could recover from radiation injury.
Author: Hayes Publisher: CRC Press ISBN: 9789057021671 Category : Science Languages : en Pages : 432
Book Description
"Molecular Genetics of Drug Resistance" forms a vital and timely review of the genetic processes behind drug resistance. Starting with an overview of the area, each chapter focuses on a particular target with important sections on drug resistance in malaria and in cancer.
Author: Solange Peters Publisher: Springer ISBN: 3319060627 Category : Medical Languages : en Pages : 255
Book Description
This book provides an up-to-date review of current management techniques for Non-Small Cell Lung Cancer. It addresses all of the latest issues that have been raised by the discovery of oncogenic drivers and the improvement of diagnosis and therapeutic methods, including new radiotherapy techniques and anticancer strategies like immunotherapy. New strategies for patients with molecular alterations and the management of particular types of cases are also highlighted. Written by recognized experts in their field, the book represents a unique and valuable resource in the field of lung cancer, both for those currently in training and for those already in clinical or research practice.
Author: Yukioki Kuroda Publisher: Springer Science & Business Media ISBN: 1461595614 Category : Medical Languages : en Pages : 480
Book Description
The papers are arranged in eight sections, addressing: antimutagens in food; antimutagens and anticarcinogens in environmental toxicology; free radicals; antitumor initiators; antitumor promoters; aspects of mammalian and human genetics; molecular aspects of mutagenesis and antimutageneis; and oncog
Author: Charlene A. McQueen Publisher: Pergamon ISBN: 9780080423012 Category : Science Languages : en Pages : 524
Book Description
Comprehensive Toxicology - the first comprehensive reference work in toxicology, is an in-depth, state-of-the-art review of toxicology of unrivalled quality. It is designed to encompass investigation from a molecular level to the intact organism. Presented in a 13-volume printed form.
Author: Peter Altmeyer Publisher: Springer Science & Business Media ISBN: 3642607713 Category : Medical Languages : en Pages : 1476
Book Description
UV radiation is recognized as the major risk factor for skin can cer. For the last three decades the incidence and mortality of skin cancer have been increasing steadily in almost all parts of the world. Unfortunately, there have been very few advances in the management and treatment of skin cancer. In comparison to other malignant tumors, skin cancer offers the unique opportuni ty to identify this tumor at an early stage. Thus, there is strong interest in preventing death by early diagnosis and prompt treat ment. The proceedings of the International Congress on Skin Cancer and UV Radiation which was held in Bochum Germany in October 1996, reflect the newest scientific standards in the field of skin cancer. The conference in Bochum was a platform for leading scientists from all over the world to discuss the complexity and diversity of UV radiation in its interaction with the skin. Starting with basic science like physiology, immunology, and molecular biochemistry of the skin as influenced by UV radiati on, the book presents a profound survey into the field of skin can cer by focusing on the latest scientific results in prevention, early detection, treatment, and epidemiology. The congress in Bochum in 1996 was organized to provide a starting point for coordinated European strategies against skin cancer with internationally renown scientists.
Author: M. Lambert
Author: M. Lambert
Author: 
Author: Jac A. Nickoloff
Author: A. Castellani
Author: Hayes
Author: Solange Peters
Author: Yukioki Kuroda
Author: Charlene A. McQueen
Author: Peter Altmeyer
Author: