Human Herpesviruses PDF Download

Author: Ann Arvin
Publisher: Cambridge University Press
ISBN: 1139461648
Category : Medical
Languages : en
Pages : 1325

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Book Description
This comprehensive account of the human herpesviruses provides an encyclopedic overview of their basic virology and clinical manifestations. This group of viruses includes human simplex type 1 and 2, Epstein–Barr virus, Kaposi's Sarcoma-associated herpesvirus, cytomegalovirus, HHV6A, 6B and 7, and varicella-zoster virus. The viral diseases and cancers they cause are significant and often recurrent. Their prevalence in the developed world accounts for a major burden of disease, and as a result there is a great deal of research into the pathophysiology of infection and immunobiology. Another important area covered within this volume concerns antiviral therapy and the development of vaccines. All these aspects are covered in depth, both scientifically and in terms of clinical guidelines for patient care. The text is illustrated generously throughout and is fully referenced to the latest research and developments.

Author: Stephen L. Sacks
Publisher: IOS Press
ISBN: 9789051992274
Category : Antiviral agents
Languages : en
Pages : 402

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Book Description
Much has been said about managing herpesvirus infections since the discovery of acyclovir more than 15 years ago. This book aims to bring practical advice to the key clinician who is faced with managing these infections. It addresses questions like: there are antiviral treatments for many of these infections, but who should be getting these drugs and who should not? What are the advantages, if any, of the new drugs over the old ones? Which patients should be targeted for intervention? What is the clinical reality of antiviral resistance? Where do the up and coming vaccines fit into the picture? When should therapy be discontinued or reassessed? How are patients presenting other than chorioretinitis in AIDS or pneumonitis in transplantation? The contributing clinician scientists deal with these questions and many more. Listed by Biological Abstracts/RRM, BIOSIS, volume 48, issue 8, August 1995 Covered by Current Contents, Life Sciences (ISI), volume 39, no. 2, Januari 1996, p. 12

Author: Peter M. Howley
Publisher: Lippincott Williams & Wilkins
ISBN: 1975112555
Category : Medical
Languages : en
Pages : 2597

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Book Description
Now in four convenient volumes, Field’s Virology remains the most authoritative reference in this fast-changing field, providing definitive coverage of virology, including virus biology as well as replication and medical aspects of specific virus families. This volume of Field’s Virology: Emerging Viruses, 7th Edition covers recent changes in emerging viruses, providing new or extensively revised chapters that reflect these advances in this dynamic field.

Author: Aydan Jones
Publisher: Hayle Medical
ISBN: 9781646475391
Category : Medical
Languages : en
Pages : 0

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Book Description
Herpesvirus refers to a type of virus that belongs to the herpesviridae family. It has been classified into eight different types which include herpes simplex type I (HSV-1), herpes simplex type II (HSV-2), varicella-zoster virus (VZV/HHV-3), Epstein-Barr virus (EBV/HHV-4), cytomegalovirus (CMV/HHV-5), herpesvirus type 6 (HBLV/HHV-6), herpesvirus type 7 (HHV-7) and Kaposi's sarcoma herpesvirus (KSHV/HHV-8). Both direct and serologic techniques are used to diagnose the human herpesvirus 6 (HHV-6) infection. One of the most prominent techniques used for quantifying viral DNA in blood, organs and other body fluids is real-time PCR. There is currently no officially approved treatment for herpes infections. However, supportive therapy including sufficient hydration and acetaminophen for fever is recommended in all patients with symptomatic HHV-6 infection. This book is compiled in such a manner, that it will provide in-depth knowledge about the diagnosis and management of human herpesviruses. It will help new researchers by foregrounding their knowledge about this virus. The book will provide comprehensive knowledge to medical students and professionals.

Author: Erik de Clercq
Publisher: Springer Science & Business Media
ISBN: 1461317150
Category : Medical
Languages : en
Pages : 420

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Book Description
Antiviral chemotherapy has come of age, and, after an initial slow pro gress, the development of new antiviral agents has proceeded at a more rapid pace and the perspectives for their clinical use have increased considerably. Now, 25 years after the first antiviral assay (idoxuridine) was introduced in the clinic, it is fitting to commemorate the beginning of the antivirals' era. In its introductory chapter B.E. Juel-Jensen touches on what may be con sidered as five of the most fundamental requirements of an antiviral drug : efficacy, relative non-toxicity, easy solubility, ready availability and rea sonable cost. Surely, the antiviral drugs that have so far been used in the clinic could still be improved upon as one or more of these five essential demands are concerned. How is all began is narrated by W.H. Prusoff. The first antiviral drugs to be used in humans were methisazone and idoxuridine, the former, which is now of archival interest, in the prevention of smallpox, the latter, which was approved for clinical use in the United States in 1962, for the topical treatment of herpetic keratitis. In terms of potency, also because of solubility reasons, idoxuridine has been superseded by trifluridine in the topical treatment of herpes simplex epithelial keratitis. H.E. Kaufman did not find trifluridine or acyclovir ef fective in the treatment of deep stromal keratitis or iritis and he reckons that other antiviral drugs (i.e. bromovinyldeoxyuridine) would not be effec tive either.

Author: Adrian Mindel
Publisher: Springer Science & Business Media
ISBN: 1447116836
Category : Medical
Languages : en
Pages : 166

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Book Description
Herpes Simplex Virus is the fifth monograph to be published in the Bloomsbury Series of Clinical Science. It provides an authoritative review of the key issues related to this common clinical problem. The characteristics of the virus, its epidemiology and the diag nosis and management of the various forms of infection are all considered. Adrian Mindel is an international authority on this subject; he joined the Academic Department of Genito-urinary Medicine at the Middlesex Hospital in 1980 and has been actively involved in HSV research since that time. His major research interests include the epidemiology and treatment of genital herpes, the epidemi ology of neo-natal herpes and the many and varied features of HSV infections in immuno-compromised patients. The continuing aim of the Bloomsbury Series is to identify the growing areas of clinical research and relate these to current and future medical practice. In Herpes Simplex Virus such aspirations have been successfully achieved. London, May 1989 Jack Tinker Preface There has been considerable interest in herpes simplex viruses (HSV) over recent years. Amongst the many reasons for this are the introduction of safe and efficacious therapy, the recognition that HSV may cause life-threatening infections in neonates and immunocompromised patients, the observation that genital herpes is one of the commonest viral sexually transmitted diseases and the possible association of HSV with cervical cancer.

Author: David Chelmow
Publisher: Cambridge University Press
ISBN: 1107675413
Category : Medical
Languages : en
Pages : 321

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Book Description
Presents almost 100 common and uncommon gynecologic problems encountered in urgent and emergency settings with an emphasis on practical management.

Author: Robert A. Norman
Publisher: Springer Science & Business Media
ISBN: 1447145798
Category : Medical
Languages : en
Pages : 334

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Book Description
This is a comprehensive, practical, densely illustrated diagnostic and therapeutic guide for all geriatric dermatology providers. The book comprises 50 chapters and over 600 color photographs on topics ranging from common conditions such as basal cell carcinoma, rosacea, and seborrheic dermatitis to unusual conditions such as angiosarcoma, dermatofibrosarcoma protuberans, and porphyria cutanea tarda. Sections include: - Inflammatory conditions (including contact dermatitis, alopecia, erythema multiforme, pemphigus, bullous pemphigoid, porphyria, pruritus, psoriasis, rosacea, seborrhea, urticaria, xerosis, and more) - Infections (fungus, herpes simplex and zoster, scabies, lice, and warts) - Skin signs in systemic disease (skin tags, cutaneous metastases, xanthomas) - Regional dermatoses (intertrigo, leg ulcers, pressure sores) - Benign tumors (chondrodermatitis, cysts, ganglion, fibrous papule, seborrheic keratoses, lentigines, and benign vascular lesions) - Pre-malignant and malignant tumors (actinic keratoses, angiosarcoma, basal cell carcinoma, dermatofibroma and dermatofibrosarcoma protuberans, intraepidermal neoplasia, Kaposi's sarcoma, keratoacanthoma, lentigo maligna, cutaneous lymphoma, Mycosis fiungoides, melanoma, nevi and moles, and squamous cell carcinoma)

Author: B. E. Juel-Jensen
Publisher: Butterworth-Heinemann
ISBN: 1483163156
Category : Medical
Languages : en
Pages : 211

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Book Description
Herpes Simplex Varicella and Zoster: Clinical Manifestations and Treatment provides an authoritative and updated clinical observation on two viruses—herpes simplex varicella and zoster. This book focuses on the similarities in tissue tropisms and character of the lesions of the two viruses. This text not only outlines the various disease patterns but gives guidance to rational treatment with antiviral agents. The topics covered include the historical background of the two viruses; description and clinical manifestations of infection in man of herpes simplex (HSV) and varicella-zoster (V-Z); definition of B virus (herpesvirus simiae); recurrent infection zoster; and treatment. This publication is intended for clinicians, but can also be a good reference for medical students and individuals conducting research in the field of virology, specifically on venereal diseases.

Author: C. Peter N. Watson
Publisher: Elsevier Publishing Company
ISBN:
Category : Medical
Languages : en
Pages : 296

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Book Description
This work brings together knowledge about the pain of herpes zoster and postherpetic neuralgia. The volume aims to expand knowledge not only of this specialized syndrome, but of every kind of chronic pain. It deals with all the basic scientific information on the acute and chronic stages of herpes zoster, as well as knowledge of all the possible treatments for this terrible affliction. A variety of treatment modalities are described, and more people are now obtaining relief than was thought possible a decade ago. research, leading to a more thorough understanding of the problems and to pain relief for those who continue to suffer.