Author: Takao Hasegawa
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages :

View

Book Description
Clinical and Research Applications of Optical Coherence Tomography Imaging in Coronary Artery Disease.

Author: Baskot Branislav
Publisher: IntechOpen
ISBN: 9789535110439
Category : Medical
Languages : en
Pages : 484

View

Book Description
The mortality from ischemic heart disease has decreased in recent years. The better understanding of risk factors associated with development of coronary artery disease has significantly contributed to this decline. Improvements in medical and interventional therapy have reduced the complications associated with acute myocardial infarction as well as revascularization. After the introduction of imaging modalities, the noninvasive characterization of regional function, perfusion and metabolism allowed for more sophisticated tissue characterization to identify reversible dysfunction with high diagnostic and prognostic accuracy. We now can legitimately claim that computed tomography angiography (CTA) of the coronary arteries is available. In the evaluation of patients with suspected coronary artery disease, many guidelines today consider CTA an alternative to stress testing. However the nuclear technique most frequently used by cardiologists is myocardial perfusion imaging (MPI). The combination of a nuclear camera with CTA allows for the attainment of coronary anatomic, cardiac function and MPI from one piece of equipment. Assessing cardiac viability is now fairly routine with these enhancements to cardiac imaging. Traditional coronary angiography presents a variety of limitations related to image acquisition, content, interpretation, and patient safety. Barriers to such improvements include the paucity of clinical outcomes studies related to new imaging technology, the need for physician and staff member training, and the costs associated with acquiring and effectively using these advances in coronary angiography. This issue is full of important information that every cardiologist needs to now.

Author: Evelyn Regar
Publisher: CRC Press
ISBN: 1841846112
Category : Medical
Languages : en
Pages : 356

View

Book Description
Given that for centuries, the standard tool to understand diseases in tissues was the microscope and that its major limitation was that only excised tissue could be used, recent technology now permits the examination of diseased tissue in vivo. Optical coherence tomography (OCT) has promising potential when applied to coronary artery disease. OCT has the capability to identify coronary plaque and to distinguish between plaques that are stable and unstable. If the plaques are stable then OCT can direct percutaneous intervention (angioplasty or stenting). Optical coherence tomography is a light-based imaging technology that allows for very high resolution imaging in biological tissues. It has been first applied in ophthalmology, where it soon became the golden standard for the assessment of (epi-) retinal processes. The unique imaging capabilities have raised the interest of researchers and clinicians in the field of cardiovascular disease, since OCT offers unique possibilities to study atherosclerosis pathophysiology in vivo. With over 1.1M Americans having a heart attack this year because of unstable plaque rupture, OCT may have an increasingly important role in the early diagnosis of coronary artery disease. This unique publication offers the reader the basic background to OCT and its role in the diagnosis and management of coronary artery disease. The Handbook of Optical Coherence Tomography in Cardiovascular Research introduces the cardiovascular application of this technology. Clinicians, biologists, engineers and physicist are discussing different aspects of cardiovascular OCT application in a multidisciplinary approach. The handbook offers the readership a concise overview on the current state of the art of vascular OCT imaging and sheds light on a variety of exciting new developments. The physics, technical principles of OCT and its application in a broad spectrum of cardiovascular research areas are summarized by highly recognized specialists. The potential of OCT in peripheral and coronary arteries and in developmental cardiology are described. Each research area is introduced by a clinical expert in the field followed by discussion of different aspects from an engineering, biomedical and clinical perspective. Specifically, the current capabilities for plaque characterization, detection of vulnerable plaque, guidance of interventional procedures, Doppler-assessment, and molecular contrast imaging are being described. The Handbook of Optical Coherence Tomography in Cardiovascular Research targets researchers and clinicians involved in the field of atherosclerosis. The summary of basic physics, engineering solutions, pre-clinical and clinical application covers all relevant aspects and will be a valuable reference source.

Author: Annapoorna Kini
Publisher: Springer
ISBN: 3319626663
Category : Medical
Languages : en
Pages : 109

View

Book Description
This atlas is a practical and fully illustrated guide to the use of intravascular OCT in diagnosis and treatment of coronary artery disease. It consists of two parts. The first part of the book provides a systematic introduction to coronary imaging with OCT. It describes how to interpret images and describes abnormal findings seen in atherosclerosis, complications after intervention, and stent assessment. The second part of the book presents real-life case studies that show how OCT is used in clinical practice in Mount Sinai to assess the disease, select appropriate treatment, and evaluate complications and results. Each case includes a brief clinical history, procedure summary, angiography and OCT images, including video material, and a discussion of how OCT affected the clinical decision-making process.

Author: Hiram G. Bezerra
Publisher: CRC Press
ISBN: 1351667688
Category : Medical
Languages : en
Pages : 305

View

Book Description
This book, written by premier authors in the field of OCT intravascular imaging, covers the best practices for using OCT to provide high resolution cross-sectional viewing for atherosclerotic plaque assessment, stent strut coverage and apposition, assessment in stent restenosis evaluation, and PCI guide and optimization. Fully illustrated thorughout in a handy, cath-lab side handbook supplemented by online movie clips, OCT Made Easy includes case studies, angiography, CT correlations, and simple techniques for getting the best image.

Author: Dr. Hakim. K. Saboowala
Publisher: Dr.Hakim Saboowala
ISBN:
Category : Medical
Languages : en
Pages : 50

View

Book Description
Need to know about Optical Coherence Tomography (OCT): A Novel, Promising Imaging Modality, for examining Coronary arteries having 10-fold higher resolution than IVUS. In cardiology, OCT is an optical analog of for IVUS examination is replaced intravascular ultrasound (IVUS), used to examine the coronary arteries. Ultrasound employed by near-infrared light with a wavelength of about 1,300 nm, which is absorbed by red blood cells, water, lipids, and protein at relatively low levels. Through a rotating glass fiber-optic system, coherent infrared light can be directed and reflected within the tissue to create a detailed tissue image with extraordinarily high resolution, and IVUS-like cross-sectional tomographic images can be obtained. OCT and IVUS differ in several respects. The resolution of OCT (to 10-20 µm) is about 10-fold higher than that of IVUS (to 100-150 µm), but the maximum depth of tissue penetration is lower with OCT (1-2 mm) than with IVUS (4-8 mm). Another important difference is related to the strong attenuation of light by blood, which originates from two sources: absorption by: · haemoglobin and · scattering by red blood cells. To examine coronary arteries, blood must first be removed during an OCT examination to eliminate massive scattering of light by red blood cells. Thus, an attempt has been made to discuss the role of OTC in Cardiology along with several relevant Tables and Illustrations for better understanding! …Dr. H. K. Saboowala. M.B.(Bom) .M.R.S.H.(London

Author: Matthew J. Price
Publisher: Elsevier Health Sciences
ISBN: 0323391044
Category : Medical
Languages : en
Pages : 185

View

Book Description
This issue of Interventional Cardiology Clinics, edited by Matthew J. Price, is devoted to Intravascular Imaging. Dr. Price assembled a group of expert contributors to review the following topics: IVUS for the assessment of coronary lesion severity and optimization of PCI; IVUS for the diagnosis and treatment of left main coronary artery disease; Fundamentals of OCT: image acquisition and interpretation; Technique and Best Practices for Intracoronary OCT; Assessment and quantitation of stent results by intracoronary OCT; PCI planning and optimization with intracoronary OCT; Advances in Automated Assessment of Intracoronary OCT and Their Clinical Application; Diagnosis and evaluation of stent thrombosis using OCT; Acute and long-term evaluation of bioresorbable scaffolds by OCT; Role of OCT in the diagnosis, evaluation, and management of spontaneous coronary artery dissection; and Neointimal Coverage after Drug-Eluting Stent Implantation: Insights from Optical Coherence Tomography.

Author: Tsakanikas, Vasilios D.
Publisher: IGI Global
ISBN: 1613500963
Category : Computers
Languages : en
Pages : 478

View

Book Description
Limitations of angiography, the traditional invasive method for assessing vascular pathology, have led to an interest in alternative invasive techniques that visualize the arterial wall and allow characterization of plaque type. These alternative techniques, which include intravascular ultrasound, angioscopy, thermography, optical coherence tomography, near infrared spectroscopy, and intravascular magnetic resonance imaging are able to provide valuable information regarding plaque vulnerability, the composition of plaque, and luminal morphology. Intravascular Imaging: Current Applications and Research Developments presents all available intravascular imaging techniques and analyzes their impact in clinical practice and research. This publication aims to inform medical specialists, biomedical engineers, bioinfomaticians, and researchers of current developments and future trends in intravascular imaging techniques, promoting continued evolution of this discipline.

Author: Ik-Kyung Jang
Publisher: Springer Nature
ISBN: 3030257118
Category : Medical
Languages : en
Pages : 198

View

Book Description
This heavily revised second edition comprehensively reviews the use of optical coherence tomography (OCT) in cardiovascular practice. It provides detailed guidance on how to properly interpret OCT images and successfully utilise it in daily clinical practice Chapters cover the development and physics associated with OCT, relevant interpretation skills, OCT imaging artifacts, plaque erosion, bioabsorbable stent, the detection of vulnerable plaque, and the use of OCT imaging in unison with other modalities such as phase contrast imaging (PCI). Areas of potential future development are also covered Cardiovascular OCT Imaging enables interventional cardiologists and cardiologists to quickly become both familiar and develop a detailed understanding of this technology to improve patient care and treatment outcome. It is a valuable reference for all practising and trainee medical professionals in cardiology, and in particular those who specialize in interventional cardiology.

Author: Evelyn Regar
Publisher: CRC Press
ISBN: 9780415383486
Category : Medical
Languages : en
Pages : 776

View

Book Description
Given that for centuries, the standard tool to understand diseases in tissues was the microscope and that its major limitation was that only excised tissue could be used, recent technology now permits the examination of diseased tissue in vivo. Optical coherence tomography (OCT) has promising potential when applied to coronary artery disease. OCT has the capability to identify coronary plaque and to distinguish between plaques that are stable and unstable. If the plaques are stable then OCT can direct percutaneous intervention (angioplasty or stenting). Optical coherence tomography is a light-based imaging technology that allows for very high resolution imaging in biological tissues. It has been first applied in ophthalmology, where it soon became the golden standard for the assessment of (epi-) retinal processes. The unique imaging capabilities have raised the interest of researchers and clinicians in the field of cardiovascular disease, since OCT offers unique possibilities to study atherosclerosis pathophysiology in vivo. With over 1.1M Americans having a heart attack this year because of unstable plaque rupture, OCT may have an increasingly important role in the early diagnosis of coronary artery disease. This unique publication offers the reader the basic background to OCT and its role in the diagnosis and management of coronary artery disease. The Handbook of Optical Coherence Tomography in Cardiovascular Research introduces the cardiovascular application of this technology. Clinicians, biologists, engineers and physicist are discussing different aspects of cardiovascular OCT application in a multidisciplinary approach. The handbook offers the readership a concise overview on the current state of the art of vascular OCT imaging and sheds light on a variety of exciting new developments. The physics, technical principles of OCT and its application in a broad spectrum of cardiovascular research areas are summarized by highly recognized specialists. The potential of OCT in peripheral and coronary arteries and in developmental cardiology are described. Each research area is introduced by a clinical expert in the field followed by discussion of different aspects from an engineering, biomedical and clinical perspective. Specifically, the current capabilities for plaque characterization, detection of vulnerable plaque, guidance of interventional procedures, Doppler-assessment, and molecular contrast imaging are being described. The Handbook of Optical Coherence Tomography in Cardiovascular Research targets researchers and clinicians involved in the field of atherosclerosis. The summary of basic physics, engineering solutions, pre-clinical and clinical application covers all relevant aspects and will be a valuable reference source.