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Click Chemistry for Biotechnology and Materials Science

Click Chemistry for Biotechnology and Materials Science PDF Author: Joerg Lahann
Publisher: John Wiley & Sons
ISBN: 0470699701
Category : Technology & Engineering
Languages : en
Pages : 437

Book Description
Mimicking natural biochemical processes, click chemistry is a modular approach to organic synthesis, joining together small chemical units quickly, efficiently and predictably. In contrast to complex traditional synthesis, click reactions offer high selectivity and yields, near-perfect reliability and exceptional tolerance towards a wide range of functional groups and reaction conditions. These ‘spring loaded’ reactions are achieved by using a high thermodynamic driving force, and are attracting tremendous attention throughout the chemical community. Originally introduced with the focus on drug discovery, the concept has been successfully applied to materials science, polymer chemistry and biotechnology. The first book to consider this topic, Click Chemistry for Biotechnology and Materials Science examines the fundamentals of click chemistry, its application to the precise design and synthesis of macromolecules, and its numerous applications in materials science and biotechnology. The book surveys the current research, discusses emerging trends and future applications, and provides an important nucleation point for research. Edited by one of the top 100 young innovators with the greatest potential to have an impact on technology in the 21st century according to Technology Review and with contributions from pioneers in the field, Click Chemistry for Biotechnology and Materials Science provides an ideal reference for anyone wanting to learn more about click reactions.

Click Chemistry for Biotechnology and Materials Science

Click Chemistry for Biotechnology and Materials Science PDF Author: Joerg Lahann
Publisher: John Wiley & Sons
ISBN: 0470699701
Category : Technology & Engineering
Languages : en
Pages : 437

Book Description
Mimicking natural biochemical processes, click chemistry is a modular approach to organic synthesis, joining together small chemical units quickly, efficiently and predictably. In contrast to complex traditional synthesis, click reactions offer high selectivity and yields, near-perfect reliability and exceptional tolerance towards a wide range of functional groups and reaction conditions. These ‘spring loaded’ reactions are achieved by using a high thermodynamic driving force, and are attracting tremendous attention throughout the chemical community. Originally introduced with the focus on drug discovery, the concept has been successfully applied to materials science, polymer chemistry and biotechnology. The first book to consider this topic, Click Chemistry for Biotechnology and Materials Science examines the fundamentals of click chemistry, its application to the precise design and synthesis of macromolecules, and its numerous applications in materials science and biotechnology. The book surveys the current research, discusses emerging trends and future applications, and provides an important nucleation point for research. Edited by one of the top 100 young innovators with the greatest potential to have an impact on technology in the 21st century according to Technology Review and with contributions from pioneers in the field, Click Chemistry for Biotechnology and Materials Science provides an ideal reference for anyone wanting to learn more about click reactions.

Click Chemistry for Biotechnology and Materials Science

Click Chemistry for Biotechnology and Materials Science PDF Author: Joerg Lahann
Publisher: John Wiley & Sons
ISBN: 9780470748855
Category : Technology & Engineering
Languages : en
Pages : 432

Book Description
Mimicking natural biochemical processes, click chemistry is a modular approach to organic synthesis, joining together small chemical units quickly, efficiently and predictably. In contrast to complex traditional synthesis, click reactions offer high selectivity and yields, near-perfect reliability and exceptional tolerance towards a wide range of functional groups and reaction conditions. These ‘spring loaded’ reactions are achieved by using a high thermodynamic driving force, and are attracting tremendous attention throughout the chemical community. Originally introduced with the focus on drug discovery, the concept has been successfully applied to materials science, polymer chemistry and biotechnology. The first book to consider this topic, Click Chemistry for Biotechnology and Materials Science examines the fundamentals of click chemistry, its application to the precise design and synthesis of macromolecules, and its numerous applications in materials science and biotechnology. The book surveys the current research, discusses emerging trends and future applications, and provides an important nucleation point for research. Edited by one of the top 100 young innovators with the greatest potential to have an impact on technology in the 21st century according to Technology Review and with contributions from pioneers in the field, Click Chemistry for Biotechnology and Materials Science provides an ideal reference for anyone wanting to learn more about click reactions.

Science of Synthesis: Click Chemistry

Science of Synthesis: Click Chemistry PDF Author: Floris P. J. T. Rutjes
Publisher: Thieme
ISBN: 3132442151
Category : Science
Languages : en
Pages : 750

Book Description
This reference work presents the state-of-the-art in the field of click chemistry, collecting the most useful, practical, and reliable methods. Click chemistry is a discipline that has grown rapidly since the introduction of this term by Barry Sharpless and Huisgen approximately two decades ago. Initially, click reactions mostly involved copper-catalyzed azide-alkyne cycloadditions and their applications to connect molecules, but gradually new types of click reactions were developed which also allowed a much wider range of applications throughout the chemical, biological, and materials sciences. This volume provides an overview of the most widely used click reactions and their scope and limitations. Written by pioneers and leaders in the field and including representative applications and experimental procedures. Newcomers to the field are enabled to instantly apply these reactions in synthesis.

Biomimetic Materials Chemistry

Biomimetic Materials Chemistry PDF Author: Stephen Mann
Publisher: John Wiley & Sons
ISBN: 9780471185970
Category : Technology & Engineering
Languages : en
Pages : 412

Book Description
* Provides new insights into materials science * Indicates the value of biology in materials science * Demonstrates how new interdisciplinary studies are influencing the fields of materials science and chemistry * Surveys this new field and shows what progress has been made as well as indicating the potential of these applications * Leading scientists review biomimetic approaches to the synthesis and processing of nanoparticles, thin patterned films, ceramics, and organic-inorganic composites * Focuses on molecule synthesis, templating, organized construction and microstructural processing of biomimetic materials related titles are: - Meyers: Molecular Biology and Biotechnology - Silver: Biocompatibility Vol.1: Polymers

Click Chemistry

Click Chemistry PDF Author: Floris Rutjes
Publisher: Wiley-VCH
ISBN: 9783527320851
Category : Biotechnology
Languages : en
Pages : 400

Book Description
This timely and much-needed publication highlights the advantages and limitations of the click approach, making this information available in one "easy-to-digest" volume. Edited by the pioneers in the field and with a list of authors reading like the "Who's Who" of click chemistry, the book assembles reviews from practitioners who have used this technique in their research. They span the fields of metal-catalyzed transformations, medicinal and bioorganic chemistry, materials and polymer science. Equally important for beginners and experienced researchers, this is the definite, first and only reference source for everyone working in the field. With a preface by Nobel prizewinner Barry Sharpless, the father of click chemistry.

Complex Macromolecular Architectures

Complex Macromolecular Architectures PDF Author: Nikos Hadjichristidis
Publisher: John Wiley & Sons
ISBN: 0470828277
Category : Science
Languages : en
Pages : 840

Book Description
The field of CMA (complex macromolecular architecture) stands at the cutting edge of materials science, and has been a locus of intense research activity in recent years. This book gives an extensive description of the synthesis, characterization, and self-assembly of recently-developed advanced architectural materials with a number of potential applications. The architectural polymers, including bio-conjugated hybrid polymers with poly(amino acid)s and gluco-polymers, star-branched and dendrimer-like hyperbranched polymers, cyclic polymers, dendrigraft polymers, rod-coil and helix-coil block copolymers, are introduced chapter by chapter in the book. In particular, the book also emphasizes the topic of synthetic breakthroughs by living/controlled polymerization since 2000. Furthermore, renowned authors contribute on special topics such as helical polyisocyanates, metallopolymers, stereospecific polymers, hydrogen-bonded supramolecular polymers, conjugated polymers, and polyrotaxanes, which have attracted considerable interest as novel polymer materials with potential future applications. In addition, recent advances in reactive blending achieved with well-defined end-functionalized polymers are discussed from an industrial point of view. Topics on polymer-based nanotechnologies, including self-assembled architectures and suprastructures, nano-structured materials and devices, nanofabrication, surface nanostructures, and their AFM imaging analysis of hetero-phased polymers are also included. Provides comprehensive coverage of recently developed advanced architectural materials Covers hot new areas such as: click chemistry; chain walking; polyhomologation; ADMET Edited by highly regarded scientists in the field Contains contributions from 26 leading experts from Europe, North America, and Asia Researchers in academia and industry specializing in polymer chemistry will find this book to be an ideal survey of the most recent advances in the area. The book is also suitable as supplementary reading for students enrolled in Polymer Synthetic Chemistry, Polymer Synthesis, Polymer Design, Advanced Polymer Chemistry, Soft Matter Science, and Materials Science courses. Color versions of selected figures can be found at www.wiley.com/go/hadjichristidis

Coupling and Decoupling of Diverse Molecular Units in Glycosciences

Coupling and Decoupling of Diverse Molecular Units in Glycosciences PDF Author: Zbigniew J. Witczak
Publisher: Springer
ISBN: 3319655876
Category : Science
Languages : en
Pages : 340

Book Description
This unique book covers the latest developments in coupling and decoupling of biomolecules containing functionalized carbohydrate components, being one of the first collections in this important area of applied medicinal chemistry. Connecting molecules, often referred as bio-conjugation, has become one of the most often performed procedures in modern medicinal chemistry. Sometimes, when the connected molecules are not useful anymore, they must be disconnected. The molecules that must be connected (coupled) may belong to both small and large molecules and include such constructs as glycoproteins, glycopeptides and glycans. In this work, more than 15 experts address a comprehensive range of potential and current uses of in vitro and in vivo bio-conjugation methodologies, leading to a variety of glycoconjugates. The analytical aspects of bio-conjugation are also here discussed. Medicinal and organic chemists from graduate level onwards will understand the appeal of this important book.

Organic Nanochemistry

Organic Nanochemistry PDF Author: Yuming Zhao
Publisher: John Wiley & Sons
ISBN: 111887045X
Category : Science
Languages : en
Pages : 292

Book Description
ORGANIC NANOCHEMISTRY How-to guide for entry-level practitioners to quickly learn the cutting-edge research concepts and methodologies of modern organic nanochemistry Organic Nanochemistry describes the fundamentals of organic nanochemistry research, encompassing modern synthetic reactions, supramolecular strategies, nanostructure and property characterization techniques, and state-of-the-art data analysis and processing methods, along with synthetic chemistry as applied to organic nanomaterials and molecular devices. Accompanying each of these principles are case studies (from basic design to detailed experimental implementation) to help the reader fully comprehend the concepts and methods involved. Various theories suitable for nanoscale simulations, including quantum mechanics, semi-empirical quantum mechanics, and molecular dynamics theories, are discussed at an introductory level. Computational examples are provided, allowing interested readers to grasp essential modelling techniques for better understanding of organic nanochemistry. The content is paired with online supplementary material that includes instructional materials and guides to using common scientific software for computational modelling and simulations. Written by a highly qualified professor, Organic Nanochemistry includes discussion on: Key concepts and theories of organic chemistry, which are essential to understand the fundamental properties of organic molecular and supramolecular systems Useful synthetic methodologies for the synthesis and functionalization of organic nanomaterials, and the chemistry and application of exotic carbon nanomaterials Supramolecular aspects in organic nanochemistry, especially the well-developed disciplines of host-guest chemistry and organic self-assembly chemistry Construction and testing of molecular devices and molecular machines and state-of-the-art computational modelling methods for properties of nanoscale organic systems Guiding the reader on a journey from familiar chemical concepts and principles to cutting-edge research of nano-science and technology, Organic Nanochemistry serves as an excellent textbook learning resource for advanced and graduate students, as well as a self-study guide or how-to reference for practicing chemists.

Chemistry of Polymeric Metal Chelates

Chemistry of Polymeric Metal Chelates PDF Author: Gulzhian I. Dzhardimalieva
Publisher: Springer
ISBN: 3319560247
Category : Technology & Engineering
Languages : en
Pages : 1036

Book Description
This book deals with the chemistry of polymeric metal chelates. The main results and the production and chemical structure of polymers with chelate units as well as the specificity of metal complex binding of different structure are presented here. This book also reveals the transformations which components undergo in the course of chelation. Special attention is paid not only to synthetic but also to natural (including living) systems. The usage of polymeric metal chelates and their development are examined. The related research was performed for chelates with chain structure. This book is useful to researchers being active in synthesis and design of macromolecular metal chelates

Materials Chemistry

Materials Chemistry PDF Author: Bradley D. Fahlman
Publisher: Springer Science & Business Media
ISBN: 9400706936
Category : Technology & Engineering
Languages : en
Pages : 742

Book Description
The 2nd edition of Materials Chemistry builds on the strengths that were recognized by a 2008 Textbook Excellence Award from the Text and Academic Authors Association (TAA). Materials Chemistry addresses inorganic-, organic-, and nano-based materials from a structure vs. property treatment, providing a suitable breadth and depth coverage of the rapidly evolving materials field — in a concise format. The 2nd edition continues to offer innovative coverage and practical perspective throughout, e.g.: the opening solid-state chemistry chapter uses color illustrations of crystalline unit cells and digital photos of models to clarify their structures. This edition features more archetypical unit cells and includes fundamental principles of X-ray crystallography and band theory. In addition, an ample amorphous-solids section has been expanded to include more details regarding zeolite syntheses, as well as ceramics classifications and their biomaterial applications. The subsequent metals chapter has been re-organized for clarity, and continues to treat the full spectrum of powder metallurgical methods, complex phase behaviors of the Fe-C system and steels, and topics such as corrosion and shape-memory properties. The mining/processing of metals has also been expanded to include photographs of various processes occurring in an actual steelmaking plant. The semiconductor chapter addresses evolution and limitations/solutions of modern transistors, as well as IC fabrication and photovoltaics. Building on the fundamentals presented earlier, more details regarding the band structure of semiconductors is now included, as well as discussions of GaAs vs. Si for microelectronics applications, and surface reconstruction nomenclature. The emerging field of ‘soft lithographic’ patterning is now included in this chapter, and thin film deposition methodologies are also greatly expanded to now include more fundamental aspects of chemical vapor deposition (CVD) and atomic layer deposition (ALD). The polymer and ‘soft’ materials chapter represents the largest expansion for the 2nd edition. This chapter describes all polymeric classes including dendritic polymers, as well as important additives such as plasticizers and flame-retardants, and emerging applications such as molecular magnets and self-repairing polymers. This edition now features ‘click chemistry’ polymerization, silicones, conductive polymers and biomaterials applications such as biodegradable polymers, biomedical devices, drug delivery, and contact lenses. Final chapters on nanomaterials and materials-characterization techniques are also carefully surveyed, focusing on nomenclature, synthetic techniques, and applications taken from the latest scientific literature. The 2nd edition has been significantly updated to now include nanotoxicity, vapor-phase growth of 0-D nanostructures, and more details regarding synthetic techniques and mechanisms for solution-phase growth of various nanomaterials. Graphene, recognized by the 2010 Nobel Prize in Physics, is now also included in this edition. Most appropriate for Junior/Senior undergraduate students, as well as first-year graduate students in chemistry, physics, or engineering fields, Materials Chemistry may also serve as a valuable reference to industrial researchers. Each chapter concludes with a section that describes important materials applications, and an updated list of thought-provoking questions. The appendices have also been updated with additional laboratory modules for materials synthesis (e.g., porous silicon) and a comprehensive timeline of major materials developments.