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Author: Karim Aderghal Publisher: ISBN: Category : Languages : en Pages : 0
Book Description
In this thesis, we are interested in the automatic classification of brain MRI images to diagnose Alzheimer's disease (AD). We aim to build intelligent models that provide decisions about a patient's disease state to the clinician based on visual features extracted from MRI images. The goal is to classify patients (subjects) into three main categories: healthy subjects (NC), subjects with mild cognitive impairment (MCI), and subjects with Alzheimer's disease (AD). We use deep learning methods, specifically convolutional neural networks (CNN) based on visual biomarkers from multimodal MRI images (structural MRI and DTI), to detect structural changes in the brain hippocampal region of the limbic cortex. We propose an approach called "2-D+e" applied to our ROI (Region-of-Interest): the hippocampus. This approach allows extracting 2D slices from three planes (sagittal, coronal, and axial) of our region by preserving the spatial dependencies between adjacent slices according to each dimension. We present a complete study of different artificial data augmentation methods and different data balancing approaches to analyze the impact of these conditions on our models during the training phase. We propose our methods for combining information from different sources (projections/modalities), including two fusion strategies (early fusion and late fusion). Finally, we present transfer learning schemes by introducing three frameworks: (i) a cross-modal scheme (using sMRI and DTI), (ii) a cross-domain scheme that involves external data (MNIST), and (iii) a hybrid scheme with these two methods (i) and (ii). Our proposed methods are suitable for using shallow CNNs for multimodal MRI images. They give encouraging results even if the model is trained on small datasets, which is often the case in medical image analysis.
Author: Karim Aderghal Publisher: ISBN: Category : Languages : en Pages : 0
Book Description
In this thesis, we are interested in the automatic classification of brain MRI images to diagnose Alzheimer's disease (AD). We aim to build intelligent models that provide decisions about a patient's disease state to the clinician based on visual features extracted from MRI images. The goal is to classify patients (subjects) into three main categories: healthy subjects (NC), subjects with mild cognitive impairment (MCI), and subjects with Alzheimer's disease (AD). We use deep learning methods, specifically convolutional neural networks (CNN) based on visual biomarkers from multimodal MRI images (structural MRI and DTI), to detect structural changes in the brain hippocampal region of the limbic cortex. We propose an approach called "2-D+e" applied to our ROI (Region-of-Interest): the hippocampus. This approach allows extracting 2D slices from three planes (sagittal, coronal, and axial) of our region by preserving the spatial dependencies between adjacent slices according to each dimension. We present a complete study of different artificial data augmentation methods and different data balancing approaches to analyze the impact of these conditions on our models during the training phase. We propose our methods for combining information from different sources (projections/modalities), including two fusion strategies (early fusion and late fusion). Finally, we present transfer learning schemes by introducing three frameworks: (i) a cross-modal scheme (using sMRI and DTI), (ii) a cross-domain scheme that involves external data (MNIST), and (iii) a hybrid scheme with these two methods (i) and (ii). Our proposed methods are suitable for using shallow CNNs for multimodal MRI images. They give encouraging results even if the model is trained on small datasets, which is often the case in medical image analysis.
Author: Danail Stoyanov Publisher: Springer ISBN: 3030008894 Category : Computers Languages : en Pages : 401
Book Description
This book constitutes the refereed joint proceedings of the 4th International Workshop on Deep Learning in Medical Image Analysis, DLMIA 2018, and the 8th International Workshop on Multimodal Learning for Clinical Decision Support, ML-CDS 2018, held in conjunction with the 21st International Conference on Medical Imaging and Computer-Assisted Intervention, MICCAI 2018, in Granada, Spain, in September 2018. The 39 full papers presented at DLMIA 2018 and the 4 full papers presented at ML-CDS 2018 were carefully reviewed and selected from 85 submissions to DLMIA and 6 submissions to ML-CDS. The DLMIA papers focus on the design and use of deep learning methods in medical imaging. The ML-CDS papers discuss new techniques of multimodal mining/retrieval and their use in clinical decision support.
Author: Jyotismita Chaki Publisher: Academic Press ISBN: 0323983952 Category : Science Languages : en Pages : 260
Book Description
Brain Tumor MRI Image Segmentation Using Deep Learning Techniques offers a description of deep learning approaches used for the segmentation of brain tumors. The book demonstrates core concepts of deep learning algorithms by using diagrams, data tables and examples to illustrate brain tumor segmentation. After introducing basic concepts of deep learning-based brain tumor segmentation, sections cover techniques for modeling, segmentation and properties. A focus is placed on the application of different types of convolutional neural networks, like single path, multi path, fully convolutional network, cascade convolutional neural networks, Long Short-Term Memory - Recurrent Neural Network and Gated Recurrent Units, and more. The book also highlights how the use of deep neural networks can address new questions and protocols, as well as improve upon existing challenges in brain tumor segmentation. Provides readers with an understanding of deep learning-based approaches in the field of brain tumor segmentation, including preprocessing techniques Integrates recent advancements in the field, including the transformation of low-resolution brain tumor images into super-resolution images using deep learning-based methods, single path Convolutional Neural Network based brain tumor segmentation, and much more Includes coverage of Long Short-Term Memory (LSTM) based Recurrent Neural Network (RNN), Gated Recurrent Units (GRU) based Recurrent Neural Network (RNN), Generative Adversarial Networks (GAN), Auto Encoder based brain tumor segmentation, and Ensemble deep learning Model based brain tumor segmentation Covers research Issues and the future of deep learning-based brain tumor segmentation
Author: M. Jorge Cardoso Publisher: Springer ISBN: 3319675583 Category : Computers Languages : en Pages : 399
Book Description
This book constitutes the refereed joint proceedings of the Third International Workshop on Deep Learning in Medical Image Analysis, DLMIA 2017, and the 6th International Workshop on Multimodal Learning for Clinical Decision Support, ML-CDS 2017, held in conjunction with the 20th International Conference on Medical Imaging and Computer-Assisted Intervention, MICCAI 2017, in Québec City, QC, Canada, in September 2017. The 38 full papers presented at DLMIA 2017 and the 5 full papers presented at ML-CDS 2017 were carefully reviewed and selected. The DLMIA papers focus on the design and use of deep learning methods in medical imaging. The ML-CDS papers discuss new techniques of multimodal mining/retrieval and their use in clinical decision support.
Author: Mayur Mallya Publisher: ISBN: Category : Languages : en Pages : 0
Book Description
Medical imaging is a cornerstone of therapy and diagnosis in modern medicine. However, the choice of imaging modality for a particular theranostic task typically involves trade-offs between the feasibility of using a particular modality (e.g., short wait times, low cost, fast acquisition, reduced radiation/invasiveness) and the expected performance on a clinical task (e.g., diagnostic accuracy, efficacy of treatment planning and guidance). The goal of this thesis is to examine the ability to apply the knowledge learned from the less feasible but better-performing (superior) modality to guide the utilization of the more-feasible yet under-performing (inferior) modality and steer it towards improved performance. To this end, we develop a lightweight guidance model - an autoencoder-like deep neural network - that learns a mapping from the latent representation of the inferior modality to the latent representation of its superior counterpart. With the incorporation of this model in the classification framework of the inferior modality, we aim to compensate for the absence of the superior modality during inference time. We focus on the application of deep learning for image-based diagnosis and examine the advantages of our method in the context of two clinical applications: multi-task skin lesion classification from clinical and dermoscopic images and brain tumor classification from multi-sequence magnetic resonance imaging (MRI) and histopathology images. For both these scenarios, we show a boost in the diagnostic performance of the inferior modality without requiring the superior modality. Furthermore, in the case of brain tumor classification, our method outperforms the model trained on the superior modality while producing comparable results to the model that uses both modalities during inference.
Author: S. Kevin Zhou Publisher: Academic Press ISBN: 0323858880 Category : Computers Languages : en Pages : 544
Book Description
Deep Learning for Medical Image Analysis, Second Edition is a great learning resource for academic and industry researchers and graduate students taking courses on machine learning and deep learning for computer vision and medical image computing and analysis. Deep learning provides exciting solutions for medical image analysis problems and is a key method for future applications. This book gives a clear understanding of the principles and methods of neural network and deep learning concepts, showing how the algorithms that integrate deep learning as a core component are applied to medical image detection, segmentation, registration, and computer-aided analysis. · Covers common research problems in medical image analysis and their challenges · Describes the latest deep learning methods and the theories behind approaches for medical image analysis · Teaches how algorithms are applied to a broad range of application areas including cardiac, neural and functional, colonoscopy, OCTA applications and model assessment · Includes a Foreword written by Nicholas Ayache
Author: Ayman El-Baz Publisher: CRC Press ISBN: 1351380737 Category : Computers Languages : en Pages : 330
Book Description
There is an urgent need to develop and integrate new statistical, mathematical, visualization, and computational models with the ability to analyze Big Data in order to retrieve useful information to aid clinicians in accurately diagnosing and treating patients. The main focus of this book is to review and summarize state-of-the-art big data and deep learning approaches to analyze and integrate multiple data types for the creation of a decision matrix to aid clinicians in the early diagnosis and identification of high risk patients for human diseases and disorders. Leading researchers will contribute original research book chapters analyzing efforts to solve these important problems.
Author: Alejandro Frangi Publisher: Academic Press ISBN: 0128136588 Category : Technology & Engineering Languages : en Pages : 700
Book Description
Medical Image Analysis presents practical knowledge on medical image computing and analysis as written by top educators and experts. This text is a modern, practical, self-contained reference that conveys a mix of fundamental methodological concepts within different medical domains. Sections cover core representations and properties of digital images and image enhancement techniques, advanced image computing methods (including segmentation, registration, motion and shape analysis), machine learning, how medical image computing (MIC) is used in clinical and medical research, and how to identify alternative strategies and employ software tools to solve typical problems in MIC. Provides an authoritative description of key concepts and methods Includes tutorial-based sections that clearly explain principles and their application to different medical domains Presents a representative selection of topics to match a modern and relevant approach to medical image computing
Author: Karim Aderghal
Author: Karim Aderghal
Author: Danail Stoyanov
Author: Jyotismita Chaki
Author: M. Jorge Cardoso
Author: Bjoern Menze
Author: Yuhui Zheng
Author: Mayur Mallya
Author: S. Kevin Zhou
Author: Ayman El-Baz
Author: Alejandro Frangi