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Author: Albert E. McPherson Publisher: ISBN: Category : Plates (Engineering) Languages : en Pages : 584
Book Description
A fixture is described for making normal-pressure tests of flat plates 5 inches in diameter in which particular care was taken to obtain rigid clamping at the edges. Results are give for 19 plates, ranging in thickness from 0.015 to 0.072 inch. The center deflections and the extreme-fiber stresses at low pressures were found to agree with theoretical values; the center deflections at high pressures were 4 to 12 percent greater than the theoretical values. Empirical curves are derived of the pressure for the beginning of permanent set as a function of the dimensions of the plate and the tensile properties of the material.
Author: Albert E. McPherson Publisher: ISBN: Category : Plates (Engineering) Languages : en Pages : 584
Book Description
A fixture is described for making normal-pressure tests of flat plates 5 inches in diameter in which particular care was taken to obtain rigid clamping at the edges. Results are give for 19 plates, ranging in thickness from 0.015 to 0.072 inch. The center deflections and the extreme-fiber stresses at low pressures were found to agree with theoretical values; the center deflections at high pressures were 4 to 12 percent greater than the theoretical values. Empirical curves are derived of the pressure for the beginning of permanent set as a function of the dimensions of the plate and the tensile properties of the material.
Author: Thomas G Smith Publisher: Springer ISBN: 1461476011 Category : Medical Languages : en Pages : 263
Book Description
Edited and authored by international experts on voltage and patch clamping, this volume is designed to help anyone undertaking experiments requiring the use of these techniques. The only book of its kind to bring together this wealth of information on theory as well as practical techniques, this is a volume that no one involved in voltage and patch clamping can afford to be without.
Author: Peter Molnar Publisher: Springer Science & Business Media ISBN: 1603270906 Category : Medical Languages : en Pages : 319
Book Description
Patch Clamp Methods and Protocols surveys the typical patch clamp applications and advises scientists on identifying problems and selecting the best technique in each instance. The experiments described require a basic level of electrophysiological training and aid the researcher in pursuing new areas of electrophysiology and using the patch clamp technique effectively. Patch Clamp Methods and Protocols is divided into three sections that cover the major areas of patch clamp application: Pharmacology, Physiology, and Biophysics. The first section provides examples and step by step instructions on how to use whole-cell and single-channel patch clamp methods for testing drugs in industrial settings. The second section provides a wide selection of patch clamp applications in physiological studies. The last part focuses on the biophysical applications of the patch clamp method using single channel recordings or statistical analysis of whole-cell currents in order to obtain parameters that describe ion channel properties or transmitter release. Individual techniques are explored within the area that they are applied most often. Researchers will find Patch Clamp Methods and Protocols to be an invaluable aid in the design and execution of a wide variety of patch clamp experiments, both on their own and in conjunction with other state-of-the-art methodologies.
Author: Areles Molleman Publisher: John Wiley & Sons ISBN: 0470856513 Category : Science Languages : en Pages : 186
Book Description
Patch clamping is a widely applied electrophysiological technique for the study of ion channels; membrane proteins that regulate the flow of ions across cellular membranes and therefore influence the physiology of all cells. Patch Clamping aims to cover the basic principles and practical applications of this important technique. Starting with a review of the history of patch clamping, the text then goes on to cover the basic principles, platforms, equipment and environmental control, and will also include coverage of preparation types, recording modes and analysis of results. This book will explain the basic principles and practical application of patch clamp electrophysiology Written in a non-technical style to ensure its broad appeal to novice users Takes a practical approach This self-contained guide provides everything a practising patch clamp electrophysiologist needs to know to master this technique, including an overview of membrane biophysics, standard experimental design, data analysis, and technical concerns
Author: CLAMP, Publisher: VIZ Media LLC ISBN: 142158753X Category : Comics & Graphic Novels Languages : en Pages : 204
Book Description
The CLAMP School is famous not just for being the world's most prestigious academy, but also for its students' penchant for partying. Scarcely a week goes by whent here isn't a festival, dance or athletic event. With so much going on, there's plenty of opportunity for something to go wrong--fortunately the CLAMP School Detectives are eager to protect all the school's goings on...especially ones in which young ladies are likely to attend. Nokoru Imonoyama is founder and leader of the group--an uber-genius who can detect a woman in distress from two kilometers away. Suoh Takamura is a class secretary and a martial arts master. Akira Ijyuin may be the youngest detective, but he's also one of the world's top chefs. Celebrations, apparitions and gastronomic sensations--they're all part of the job for the CLAMP School Detectives! -- VIZ Media
Author: Alain Destexhe Publisher: Springer Science & Business Media ISBN: 0387892796 Category : Medical Languages : en Pages : 428
Book Description
Dynamic-clamp is a fascinating electrophysiology technique that consists of merging living neurons with computational models. The dynamic-clamp (also called “conductance injection”) allows experimentalists and theoreticians to challenge neurons (or any other type of cell) with complex conductance stimuli generated by a computer. The technique can be implemented from neural simulation environments and a variety of custom-made or commercial systems. The real-time interaction between the computer and cell also enables the design of recording paradigms with unprecedented accuracy via a computational model of the electrode. Dynamic-Clamp: From Principles to Applications contains contributions from leading researchers in the field, who investigate these paradigms at the cellular or network level, in vivo and in vitro, and in different brain regions and cardiac cells. Topics discussed include the addition of artificially-generated synaptic activity to neurons; adding, amplifying or neutralizing voltage-dependent conductances; creating hybrid networks with real and artificial cells; attaching simulated dendritic tree structures to the living cell; and connecting different neurons. This book will be of interest to experimental biophysicists, neurophysiologists, and cardiac physiologists, as well as theoreticians, engineers, and computational neuroscientists. Graduate and undergraduate students will also find up-to-date coverage of physiological problems and how they are investigated.
Author: Albert E. McPherson
Author: Albert E. McPherson
Author: John L. Sewall
Author: Thomas G Smith
Author: Peter Molnar
Author: Lester Gray French
Author: USA Patent Office
Author: Areles Molleman
Author: CLAMP,
Author: 
Author: Alain Destexhe