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Author: Andrea L. Bonnicksen Publisher: Georgetown University Press ISBN: 1589017196 Category : Medical Languages : en Pages : 182
Book Description
In his 2006 State of the Union speech, President George W. Bush asked the U.S. Congress to prohibit the "most egregious abuses of medical research," such as the "creation of animal–human hybrids." The president's message echoed that of a 2004 report by the President's Council on Bioethics, which recommended that hybrid human–animal embryos be banned by Congress. Discussions of early interspecies research, in which cells or DNA are interchanged between humans and nonhumans at early stages of development, can often devolve into sweeping statements, colorful imagery, and confusing policy. Although today's policy advisory groups are becoming more informed, debate is still limited by the interchangeable use of terms such as chimeras and hybrids, a tendency to treat all forms of interspecies alike, the failure to distinguish between laboratory research and procreation, and not enough serious policy justification. Andrea Bonnicksen seeks to understand reasons behind support of and disdain for interspecies research in such areas as chimerism, hybridization, interspecies nuclear transfer, cross-species embryo transfer, and transgenics. She highlights two claims critics make against early interspecies studies: that the research will violate human dignity and that it can lead to procreation. Are these claims sufficient to justify restrictive policy? Bonnicksen carefully illustrates the challenges of making policy for sensitive and often sensationalized research—research that touches deep-seated values and that probes the boundary between human and nonhuman animals.
Author: Andrea L. Bonnicksen Publisher: Georgetown University Press ISBN: 1589017196 Category : Medical Languages : en Pages : 182
Book Description
In his 2006 State of the Union speech, President George W. Bush asked the U.S. Congress to prohibit the "most egregious abuses of medical research," such as the "creation of animal–human hybrids." The president's message echoed that of a 2004 report by the President's Council on Bioethics, which recommended that hybrid human–animal embryos be banned by Congress. Discussions of early interspecies research, in which cells or DNA are interchanged between humans and nonhumans at early stages of development, can often devolve into sweeping statements, colorful imagery, and confusing policy. Although today's policy advisory groups are becoming more informed, debate is still limited by the interchangeable use of terms such as chimeras and hybrids, a tendency to treat all forms of interspecies alike, the failure to distinguish between laboratory research and procreation, and not enough serious policy justification. Andrea Bonnicksen seeks to understand reasons behind support of and disdain for interspecies research in such areas as chimerism, hybridization, interspecies nuclear transfer, cross-species embryo transfer, and transgenics. She highlights two claims critics make against early interspecies studies: that the research will violate human dignity and that it can lead to procreation. Are these claims sufficient to justify restrictive policy? Bonnicksen carefully illustrates the challenges of making policy for sensitive and often sensationalized research—research that touches deep-seated values and that probes the boundary between human and nonhuman animals.
Author: Jochen Taupitz Publisher: Springer Science & Business Media ISBN: 3540938699 Category : Law Languages : en Pages : 1032
Book Description
National, European and international concepts and strategies concerning the legal and ethical framework of chimera and hybrid research are still largely missing, even though they are absolutely necessary in order to use the potential of chimera and hybrid research effectively and efficiently for the benefit of science and society. The outcome of the CHIMBRIDS-Project successfully sheds light on the chances and risks of this research and provides legal solutions to existing problems in order to help decision-makers fulfil their tasks in an informed and efficient manner. This comprehensive volume details the complete results, contributed by 40 scholars from 10 member states of the European Union, Canada, China, Israel, Japan, Switzerland and the US, with descriptive reports of the legal situation in specific countries and in-depth analysis of all scientific, medical, ethical and legal implications of chimera and hybrid research.
Author: Insoo Hyun Publisher: Humana ISBN: 9781493995264 Category : Science Languages : en Pages : 234
Book Description
This volume addresses challenging new questions surrounding stem cell-based chimera research. This book is organized into three parts: Part One provides readers with a summary of different human donor cell types. The chapters in this section discuss ways to evaluate new types of pluripotent stem cells; the derivation of naïve and primed pluripotent stem cells from mouse preimplantation embryos; and the ethical and regulatory complexities of informed consent for the procurement of somatic cells. Part Two discusses methods for generating chimeras. The chapters here look at chick models and human-chick organizer grafts; generating human-pig interspecies chimeras; and techniques for transplanting mouse neural stem cells into a mouse disease model for stroke. Part Three concludes the book with a look at ongoing ethical controversies and new scientific directions. Chapters in this part cover the ethics of crossing the xenobarrier; animal welfare; experimentation with spermatogonial stem cells; and cautious approaches to human-monkey chimera studies to further understand complex human brain disorders. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Chimera Research: Methods and Protocols is a valuable resource for scientists interesting in using chimeras as a research tool while also taking into consideration their complex ethical scopes.
Author: Richard A. E. Tilney-Bassett Publisher: Cambridge University Press ISBN: 9780521427876 Category : Science Languages : en Pages : 208
Book Description
This book, which was originally published in 1986, introduces the reader to the main steps in the analysis of chimeras, explains their structural and developmental basis, and the ways of classifying and manipulating them. The twelve chapters separate types of chimeras according to their origin - by grafting or polyploidy; their structure - sectorial or periclinal; or according to the varied parts of the plant most affected - tubers, leaves, flowers or fruit. Throughout the book care is taken to distinguish between the activity of the growing-point in determining chimera structure, and the role of gene expression in determining appearance. Examples of the experimental uses of chimeras are given and of the valuable role they can play in studying fundamental questions of anatomical development; the disadvantages of chimeras in mutation breeding are discussed too.
Author: National Research Council Publisher: National Academies Press ISBN: 030916785X Category : Science Languages : en Pages : 223
Book Description
Expanding on the National Research Council's Guide for the Care and Use of Laboratory Animals, this book deals specifically with mammals in neuroscience and behavioral research laboratories. It offers flexible guidelines for the care of these animals, and guidance on adapting these guidelines to various situations without hindering the research process. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research offers a more in-depth treatment of concerns specific to these disciplines than any previous guide on animal care and use. It treats on such important subjects as: The important role that the researcher and veterinarian play in developing animal protocols. Methods for assessing and ensuring an animal's well-being. General animal-care elements as they apply to neuroscience and behavioral research, and common animal welfare challenges this research can pose. The use of professional judgment and careful interpretation of regulations and guidelines to develop performance standards ensuring animal well-being and high-quality research. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research treats the development and evaluation of animal-use protocols as a decision-making process, not just a decision. To this end, it presents the most current, in-depth information about the best practices for animal care and use, as they pertain to the intricacies of neuroscience and behavioral research.
Author: Andy Lavender Publisher: Routledge ISBN: 1136467203 Category : Performing Arts Languages : en Pages : 248
Book Description
Performance in the Twenty-First Century: Theatres of Engagement addresses the reshaping of theatre and performance after postmodernism. Andy Lavender argues provocatively that after the ‘classic’ postmodern tropes of detachment, irony, and contingency, performance in the twenty-first century engages more overtly with meaning, politics and society. It involves a newly pronounced form of personal experience, often implicating the body and/or one’s sense of self. This volume examines a range of performance events, including work by both emergent and internationally significant companies and artists such as Rimini Protokoll, Blast Theory, dreamthinkspeak, Zecora Ura, Punchdrunk, Ontroerend Goed, Kris Verdonck, Dries Verhoeven, Rabih Mroué, Derren Brown and David Blaine. It also considers a wider range of cultural phenomena such as online social networking, sports events, installations, games-based work and theme parks, where principles of performance are in play. Performance in the Twenty-First Century is a compelling and provocative resource for anybody interested in discovering how performance theory can be applied to cutting-edge culture, and indeed the world around them.
Author: Rafi Youatt Publisher: University of Michigan Press ISBN: 047212644X Category : Political Science Languages : en Pages : 209
Book Description
This book explores the ways that international politics is a form of interspecies politics, one that involves the interactions, ideas, and practices of multiple species, both human and nonhuman, to generate differences and create commonalities. While we frequently think of having an international politics “of” the environment, a deep and thoroughgoing anthropocentrism guides our idea of what political life can be, which prevents us from thinking about a politics “with” the environment. This anthropocentric assumption about politics drives both ecological degradation and deep forms of interhuman injustice and hierarchy. Interspecies Politics challenges that assumption, arguing that a truly ecological account of interstate life requires us to think about politics as an activity that crosses species lines. It therefore explores a postanthropocentric account of international politics, focusing on a series of cases and interspecies practices in the American borderlands, ranging from the US-Mexico border in southern Texas, to Guantánamo Bay in Cuba, to Isle Royale, near the US-Canadian border. The book draws on international relations, environmental political theory, anthropology, and animal studies, to show how key international dimensions of states—sovereignty, territory, security, rights—are better understood as forms of interspecies assemblage that both generate new forms of multispecies inclusion, and structure forms of violence and hierarchy against human and nonhuman alike.
Author: Holly Tucker Publisher: W. W. Norton & Company ISBN: 0393080420 Category : Science Languages : en Pages : 337
Book Description
"Excellent…Tucker’s chronicle of the world of 17th-century science in London and Paris is fascinating." —The Economist In December 1667, maverick physician Jean Denis transfused calf’s blood into one of Paris’s most notorious madmen. Days later, the madman was dead and Denis was framed for murder. A riveting exposé of the fierce debates, deadly politics, and cutthroat rivalries behind the first transfusion experiments, Blood Work takes us from dissection rooms in palaces to the streets of Paris, providing an unforgettable portrait of an era that wrestled with the same questions about morality and experimentation that haunt medical science today.
Author: C. Ben Mitchell Publisher: B&H Publishing Group ISBN: 143367114X Category : Religion Languages : en Pages : 222
Book Description
A biblically informed guidebook for Christians facing difficult health care decisions, from the making of life (infertility, organ donation, cloning) and taking of life (abortion, euthanasia) to the technologically driven faking of life (genetic engineering, etc.).
Author: Michael Bess Publisher: Beacon Press ISBN: 0807066621 Category : Medical Languages : en Pages : 322
Book Description
A panoramic overview of biotechnologies that can endlessly boost human capabilities and the drastic changes these “superhuman” traits could trigger Biotechnology is moving fast. In the coming decades, advanced pharmaceuticals, bioelectronics, and genetic interventions will be used not only to heal the sick but to boost human physical and mental performance to unprecedented levels. People will have access to pills that make them stronger and faster, informatic devices will interface seamlessly with the human brain, and epigenetic modification may allow people to reshape their own physical and mental identities at will. Until recently, such major technological watersheds—like the development of metal tools or the industrialization of manufacturing—came about incrementally over centuries or longer. People and social systems had time to adapt: they gradually developed new values, norms, and habits to accommodate the transformed material conditions. But contemporary society is dangerously unprepared for the dramatic changes it is about to experience down this road on which it is already advancing at an accelerating pace. The results will no doubt be mixed. People will live longer, healthier lives, will fine-tune their own thought processes, and will generate staggeringly complex and subtle forms of knowledge and insight. But these technologies also threaten to widen the rift between rich and poor, to generate new forms of social and economic division, and to force people to engage in constant cycles of upgrades and boosts merely to keep up. Individuals who boost their traits beyond a certain threshold may acquire such extreme capabilities that they will no longer be recognized as unambiguously human. In this important and timely book, prize-winning historian Michael Bess provides a clear, nontechnical overview of cutting-edge biotechnology and paints a vivid portrait of a near-future society in which bioenhancement has become a part of everyday life. He surveys the ethical questions raised by the enhancement enterprise and explores the space for human agency in dealing with the challenges that these technologies will present. Headed your way over the coming decades: new biotechnologies that can powerfully alter your body and mind. The possibilities are tantalizing: • Rejuvenation therapies offering much longer lives (160 and even beyond) in full vigor and mental acuity • Cognitive enhancement through chemical or bioelectronic means (the rough equivalent of doubling or tripling IQ scores) • Epigenetic tools for altering some of your genetically influenced traits at any point in your lifetime (body shape, athletic ability, intelligence, personality) • Bioelectronic devices for modulating your own brain processes, including your “pleasure centers” (a potentially non-stop high) • Direct control of machines by thought, and perhaps direct communication with other people, brain-to-brain (a new dimension of sharing and intimacy) But some of the potential consequences are also alarming: • A growing rift between the biologically enhanced and those who can’t afford such modifications • A constant cycle of upgrades and boosts as the bar of “normal” rises ever higher—“Humans 95, Humans XP, Humans 8” • The fragmentation of humankind into rival “bioenhancement clusters” • A gradually blurring boundary between “person” and “product” • Extreme forms of self-modification, with some individuals no longer recognized as unambiguously human
Author: Andrea L. Bonnicksen
Author: Andrea L. Bonnicksen
Author: Jochen Taupitz
Author: Insoo Hyun
Author: Richard A. E. Tilney-Bassett
Author: National Research Council
Author: Andy Lavender
Author: Rafi Youatt
Author: Holly Tucker
Author: C. Ben Mitchell
Author: Michael Bess