Author: Antony Bacic Publisher: Academic Press ISBN: 9780080920542 Category : Science Languages : en Pages : 350
Book Description
Chemistry, Biochemistry, and Biology of 1-3 Beta Glucans and Related Polysaccharides presents a comprehensive, systematic and authoritative survey of information about a family of chemically related, but functionally diverse, naturally occurring polysaccharides--the (1-3)-glucans. International contributors describe the chemical and physicochemical properties of these glucans and their derivatives and the molecular biological and structural aspects of the enzymes involved in their formation and breakdown. A detailed analysis of their physiological roles in the various biological situations in which they are found will be provided. Additionally, evolutionary relationships among the family of these glucans will be described. Topics of medical relevance include detailing the glucans' interactions with the immune system and research for cancer therapy applications Web resource links allow scientists to explore additional beta glucan research Separate indexes divided into Species and Subject for enhanced searchability
Author: Václav Větvička Publisher: Bentham Science Publishers ISBN: 1608052109 Category : Science Languages : en Pages : 91
Book Description
"?-Glucan is generally considered to be a very safe immunomodulator. It is a well-known biological response modifier (BRM) that has been used as an adjuvant therapy for cancer since 1980, mostly in Japan. ?-Glucan enhances the innate host defense against c"
Author: Shih-Houng Young Publisher: CRC Press ISBN: 9780203020814 Category : Medical Languages : en Pages : 244
Book Description
The investigation of indoor air quality has shown that microbial contamination is often a problem in buildings. Recent evidence indicates that fungi are often a part of the picture. A component of the fungal cell wall, 1 3-glucans not only affect human health, they are a marker for the existence of fungi in environmental samples. Toxicology
Author: Vaclav Vetvicka Publisher: Bentham Science Publishers ISBN: 1608052605 Category : Science Languages : en Pages : 213
Book Description
Despite of the efforts of pharmaceutical researchers to find new medicaments, nature offers many substances with healing properties—beta-glucans belong to this group of compounds. The second volume of the e-book series, Biology and Chemistry of Beta-Glucan, provides new knowledge about these important polysaccharides. In order to understand the role of beta-glucans, it is necessary to control the purity and to determine their composition and structure. This volume presents modern chemical and separation methods which are applied in structural analysis of glucans. As a result of structural analyses, it can be concluded that beta-glucans of different origin vary in chain length, number and types of branching. The book further discusses the biological effects of tailored oligomers and synthetic beta-glucans, including innovative use of enzymatic processes in the synthesis of these compounds. This volume also discusses a hypothesis of beta-glucans’ increasing impact on the photodynamic therapy. In spite of many scientific papers describing the positive role of beta-glucans in protection against diseases, certain epidemiological data suggest that specific illnesses can be related to beta-glucan exposure. The fact of whether or not beta-glucan is an accompanying substance of these biologically active agents is also questioned. Biology and Chemistry of Beta-Glucan: Volume 2 focuses on the strictly scientific basis on the effects of beta-glucan on human health as well as other possibilities of beta-glucan application, such as protection of aquaculture against diseases.
Author: Bruce A. Stone Publisher: La Trobe University Institute of Latin American Studies ISBN: Category : Science Languages : en Pages : 818
Book Description
This book presents a comprehensive and systematic survey on (1-3)-B-glucans. Glucans with the (1-3)-B-glucosidic linkage as a major feature, are present in most higher plants and many lower plants and microorganisms. They may occur as major structural or storage components or be formed at very specific sites in response to particular developmental events or stimuli. In many cases their functional role is a mystery, in others it is well established. Their distribution and physiological involvement indicates that they are important to fields such as agriculture and biotechnology, and may also have an impact in medicine, through their role in immunology and cancer therapy.
Author: Desiree Nedra Karunaratne Publisher: BoD – Books on Demand ISBN: 9535108190 Category : Science Languages : en Pages : 652
Book Description
The complex world of polysaccharides is a compilation of the characteristics of a variety of polysaccharides from plants, animals and microorganisms. The diversity of these polysaccharides arises from the structural variations and the monosaccharide content which is under genetic control. The chemical and physical properties have made them useful in many pharmaceutical, food and industrial applications. These properties of the polysaccharides determine their biological activity and their function in various applications. The role played by polysaccharides in preservation and protection of food, as carriers of nutrients and drugs, their ability to interact with molecules both for efficient delivery as well as improving textures of food colloids and their use as therapeutics are some of the functions discussed.
Author: Severian Dumitriu Publisher: CRC Press ISBN: 1420030825 Category : Medical Languages : en Pages : 1210
Book Description
Completely revised and expanded to reflect the latest advancements in the field, Polysaccharides: Structural Diversity and Functional Versatility, Second Edition outlines fundamental concepts in the structure, function, chemistry, and stability of polysaccharides and reveals new analytical techniques and applications currently impacting the cosmeti
Author: Bertram O. Fraser-Reid Publisher: Springer Science & Business Media ISBN: 3642568742 Category : Science Languages : en Pages : 2817
Book Description
Glycostructures play a highly diverse and crucial role in a myriad of organisms and systems in biology, physiology, medicine, and bioengineering and technology. Only in recent years have the tools been developed to partly understand the highly complex functions and chemistry behind them. In this set the editors present up-to-date information on glycostructures, their chemistry and chemical biology, in the form of a comprehensive survey. The text is accompanied by over 2000 figures, chemical structures and reaction schemes and more than 9000 references. The accompanying CD-ROM enables, besides text searches, searches for structures, schemes, and other information.
Author: Jean-Paul Latgé Publisher: Springer Nature ISBN: 3030499286 Category : Science Languages : en Pages : 369
Book Description
This book illustrates, that the fungal cell wall is critical for the biology and ecology of all fungi and especially for human fungal pathogens. Readers will learn, that the composition of the fungal cell wall is a unique structure, which cannot be found in the human host. Consequently, the chapters outline, how the immune systems of both animals and humans have evolved to recognize conserved and unique elements of the fungal cell wall. As an application example, the authors also show, that the three-dimensional structures of the cell wall are excellent targets for the development of antifungal agents and chemotherapeutic strategies. With the combination of biological findings and medical outlooks, this volume is a fascinating read for scientists, clinicians and biomedical students.
Author: Atta-ur-Rahman Publisher: Elsevier ISBN: 0444639365 Category : Science Languages : en Pages : 454
Book Description
Studies in Natural Products Chemistry, Volume 53, covers the synthesis, testing, and recording of the medicinal properties of natural products, providing cutting-edge accounts of the fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis, and pharmacology of a diverse array of bioactive natural products. Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then determine the structures and biological activity of natural products rapidly, thus opening up exciting opportunities in the field of new drug development to the pharmaceutical industry that are discussed and highlighted in this series. Focuses on the chemistry of bioactive natural products Contains contributions by leading authorities in the field Presents sources of new pharmacophores