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Characterization of a Noninvasive, in Vivo, Microscopic Hyperspectral Imaging System for Microvascular Visualization

Characterization of a Noninvasive, in Vivo, Microscopic Hyperspectral Imaging System for Microvascular Visualization PDF Author: Bhavesh Shah
Publisher:
ISBN: 9780542610493
Category : Biomedical engineering
Languages : en
Pages :

Book Description
Instrumentation with clinical implications for imaging the human oculus was developed, based upon the hyperspectral imaging modality. The novel, non invasive, microscopic multi-modal hyperspectral imaging system, which operates in the visible as well as near infrared region, is capable of generating images illustrating spatial distribution of oxyhemoglobin contributions. The device principally comprises of a liquid crystal tunable filter and a focal plane array detector that is integrated to the slit lamp microscope. A proof of principle clinical study involving ten healthy subjects was undertaken to image the microvascular structure within the dermal tissue within the near infrared region, however these results are not validated. The spectral range used in the study was 650--1050nm, with a spectral resolution of 5nm, magnification of 10X to obtain a 35 ms acquisition time and a spatial resolution of 0.054 mm at binning of 1 x 1. The successful dermal microvascular study paved way for imaging the human eye using the visible region, wherein the anterior scleral surface was visualized in seven healthy subjects to spatially map the oxyhemoglobin contributions in the microvasculature perfusing the sclera. The spectral range used in the human eye study was 520--602nm, with a spectral resolution of 2nm, magnification of 10X to obtain a 5 ms acquisition time and a spatial resolution of 0.038 mm at binning of 2 x 2.

Characterization of a Noninvasive, in Vivo, Microscopic Hyperspectral Imaging System for Microvascular Visualization

Characterization of a Noninvasive, in Vivo, Microscopic Hyperspectral Imaging System for Microvascular Visualization PDF Author: Bhavesh Shah
Publisher:
ISBN: 9780542610493
Category : Biomedical engineering
Languages : en
Pages :

Book Description
Instrumentation with clinical implications for imaging the human oculus was developed, based upon the hyperspectral imaging modality. The novel, non invasive, microscopic multi-modal hyperspectral imaging system, which operates in the visible as well as near infrared region, is capable of generating images illustrating spatial distribution of oxyhemoglobin contributions. The device principally comprises of a liquid crystal tunable filter and a focal plane array detector that is integrated to the slit lamp microscope. A proof of principle clinical study involving ten healthy subjects was undertaken to image the microvascular structure within the dermal tissue within the near infrared region, however these results are not validated. The spectral range used in the study was 650--1050nm, with a spectral resolution of 5nm, magnification of 10X to obtain a 35 ms acquisition time and a spatial resolution of 0.054 mm at binning of 1 x 1. The successful dermal microvascular study paved way for imaging the human eye using the visible region, wherein the anterior scleral surface was visualized in seven healthy subjects to spatially map the oxyhemoglobin contributions in the microvasculature perfusing the sclera. The spectral range used in the human eye study was 520--602nm, with a spectral resolution of 2nm, magnification of 10X to obtain a 5 ms acquisition time and a spatial resolution of 0.038 mm at binning of 2 x 2.

Techniques and Applications of Hyperspectral Image Analysis

Techniques and Applications of Hyperspectral Image Analysis PDF Author: Hans Grahn
Publisher: John Wiley & Sons
ISBN: 9780470010877
Category : Science
Languages : en
Pages : 390

Book Description
Techniques and Applications of Hyperspectral Image Analysis gives an introduction to the field of image analysis using hyperspectral techniques, and includes definitions and instrument descriptions. Other imaging topics that are covered are segmentation, regression and classification. The book discusses how high quality images of large data files can be structured and archived. Imaging techniques also demand accurate calibration, and are covered in sections about multivariate calibration techniques. The book explains the most important instruments for hyperspectral imaging in more technical detail. A number of applications from medical and chemical imaging are presented and there is an emphasis on data analysis including modeling, data visualization, model testing and statistical interpretation.

Characterization of Hyperspectral Imaging System

Characterization of Hyperspectral Imaging System PDF Author: Nicholas Bautista Targhetta
Publisher:
ISBN:
Category : Imaging systems
Languages : en
Pages : 120

Book Description


Visualization in Biomedical Microscopies

Visualization in Biomedical Microscopies PDF Author: Andres Kriete
Publisher: Wiley-VCH
ISBN: 9783527284450
Category : Science
Languages : en
Pages : 405

Book Description
This book is a guide to biomedical visualization in microscopy, a new method of computer-aided three-dimensional imaging. Aspects of computer graphics, image analysis, specimen preparation, and microscopy technology are combined in this multiauthored work to provide thorough coverage of the most important biomedical applications of visualization. Examples include three-dimensional imaging of serial mechanical sections in light and electron microscopy as well as non-invasive sections in microtomography and confocal microscopy. Special emphasis is placed on advanced 3-D imaging with laser scanning microscopes. An exciting new technique presented here is four-dimensional visualization: the time- resolved imaging of in-vivo microstructures. Serving as an excellent introductory text and reference source for microscopists, computer scientists, and researchers in biology and clinical medicine, this book also contains over 150 illustrations, many in color, as well as a fold-out poster of a computer-generated image of cell mitosis.

Chapter A New Compact VNIR Hyperspectral Imaging System for Non-Invasive Analysis in the FineArt and Architecture Fields

Chapter A New Compact VNIR Hyperspectral Imaging System for Non-Invasive Analysis in the FineArt and Architecture Fields PDF Author: Marcello Picollo
Publisher:
ISBN: 9788864537078
Category :
Languages : en
Pages : 0

Book Description
A new compact Specim IQ hyperspectral camera working in the 400-1000 nm range has been launched on the market. Its use in the investigation of different artworks and under diverse environmental conditions will be presented.

Chapter A New Compact VNIR Hyperspectral Imaging System for Non-Invasive Analysis in the FineArt and Architecture Fields

Chapter A New Compact VNIR Hyperspectral Imaging System for Non-Invasive Analysis in the FineArt and Architecture Fields PDF Author:
Publisher:
ISBN: 9788864537078
Category :
Languages : en
Pages : 0

Book Description
A new compact Specim IQ hyperspectral camera working in the 400-1000 nm range has been launched on the market. Its use in the investigation of different artworks and under diverse environmental conditions will be presented.

Index Medicus

Index Medicus PDF Author:
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 2432

Book Description
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.

Imaging in Dermatology

Imaging in Dermatology PDF Author: Michael R. Hamblin
Publisher: Academic Press
ISBN: 0128028599
Category : Science
Languages : en
Pages : 562

Book Description
Imaging in Dermatology covers a large number of topics in dermatological imaging, the use of lasers in dermatology studies, and the implications of using these technologies in research. Written by the experts working in these exciting fields, the book explicitly addresses not only current applications of nanotechnology, but also discusses future trends of these ever-growing and rapidly changing fields, providing clinicians and researchers with a clear understanding of the advantages and challenges of laser and imaging technologies in skin medicine today, along with the cellular and molecular effects of these technologies. - Outlines the fundamentals of imaging and lasers for dermatology in clinical and research settings - Provides knowledge of current and future applications of dermatological imaging and lasers - Coherently structured book written by the experts working in the fields covered

Encyclopedia of Cell Biology

Encyclopedia of Cell Biology PDF Author:
Publisher: Academic Press
ISBN: 0123947960
Category : Science
Languages : en
Pages : 2972

Book Description
The Encyclopedia of Cell Biology, Four Volume Set offers a broad overview of cell biology, offering reputable, foundational content for researchers and students across the biological and medical sciences. This important work includes 285 articles from domain experts covering every aspect of cell biology, with fully annotated figures, abundant illustrations, videos, and references for further reading. Each entry is built with a layered approach to the content, providing basic information for those new to the area and more detailed material for the more experienced researcher. With authored contributions by experts in the field, the Encyclopedia of Cell Biology provides a fully cross-referenced, one-stop resource for students, researchers, and teaching faculty across the biological and medical sciences. Fully annotated color images and videos for full comprehension of concepts, with layered content for readers from different levels of experience Includes information on cytokinesis, cell biology, cell mechanics, cytoskeleton dynamics, stem cells, prokaryotic cell biology, RNA biology, aging, cell growth, cell Injury, and more In-depth linking to Academic Press/Elsevier content and additional links to outside websites and resources for further reading A one-stop resource for students, researchers, and teaching faculty across the biological and medical sciences

Medical Image Analysis

Medical Image Analysis PDF Author: Alejandro Frangi
Publisher: Academic Press
ISBN: 0128136588
Category : Technology & Engineering
Languages : en
Pages : 700

Book Description
Medical Image Analysis presents practical knowledge on medical image computing and analysis as written by top educators and experts. This text is a modern, practical, self-contained reference that conveys a mix of fundamental methodological concepts within different medical domains. Sections cover core representations and properties of digital images and image enhancement techniques, advanced image computing methods (including segmentation, registration, motion and shape analysis), machine learning, how medical image computing (MIC) is used in clinical and medical research, and how to identify alternative strategies and employ software tools to solve typical problems in MIC. - An authoritative presentation of key concepts and methods from experts in the field - Sections clearly explaining key methodological principles within relevant medical applications - Self-contained chapters enable the text to be used on courses with differing structures - A representative selection of modern topics and techniques in medical image computing - Focus on medical image computing as an enabling technology to tackle unmet clinical needs - Presentation of traditional and machine learning approaches to medical image computing